Clinical trials: Magnetic Resonance Imaging
Depression - Major Depressive Disorder, Bipolar Disorder (BD)
Flumazenil for Benzodiazepine Reversal in Electroconvulsive Therapy
The goal of this study is to investigate whether administering flumazenil to reverse the effects of benzodiazepines and/or zopiclone during electroconvulsive therapy (ECT) can help reduce cognitive side effects without…
- Conditions
- Depression - Major Depressive Disorder, Bipolar Disorder (BD), Functional Magnetic Resonance Imaging (fMRI), Cognition
- Trial name
- FLEET (NCT07619092)
- Testing
- Flumazenil, Electroconvulsive therapy (ECT)
- Where
- Denmark
- Volunteers
- 145 people
- Sponsor
- Anders Jørgensen
Opioid-Related Disorders, Mobile Applications
Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder
The proposed clinical trial would evaluate the use of smartphone applications ("apps", which have well-established efficacy in reducing cigarette and alcohol use) to prevent relapse among patients receiving medication-assisted…
- Conditions
- Opioid-Related Disorders, Mobile Applications, Opiate Substitution Treatment, Magnetic Resonance Imaging
- Trial name
- NCT05336188
- Testing
- Smartphone
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- University of Arkansas
Multiparametric, Magnetic Resonance Imaging
Multiparametric MRI for Bladder Cancer: Validation of VI-RADS for the Detection of Muscle Invasive Bladder Cancer
This research aimed to determine how accurately multiparametric magnetic resonance imaging (MRI), when interpreted using the VI-RADS scoring system, can distinguish between invasive and non-invasive bladder cancer.
- Conditions
- Multiparametric, Magnetic Resonance Imaging, Validation, Vesical Imaging Reporting and Data System (VI-RADS)
- Trial name
- NCT07578233
- Testing
- Magnetic resonance imaging
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Chewing Problem, Cognitive Decline
Cognitive Changes and Neural Correlates After Rehabilitation of Masticatory Function in Elderly -an Intervention Study
Today in elderly tooth loss and loss of oral function is widespread, but it is an underexplored modifiable risk factor potentially contributing to the development of dementia.
- Conditions
- Chewing Problem, Cognitive Decline, Magnetic Resonance Imaging, Degenerative; Dementia
- Trial name
- NCT04458207
- Testing
- Oral prosthetic rehabilitation
- Where
- 2 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Folktandvården Stockholms län AB
Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET
FAPI PET/CT Imaging in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (FAPI-ARVC))
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease associated with fibrofatty myocardial replacement, ventricular arrhythmias, and an increased risk of sudden cardiac death.
- Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET, Cardiac Magnetic Resonance Imaging
- Trial name
- FAPI-ARVC (NCT07563660)
- Testing
- 68Ga-DOTA-SA-FAPI PET/CT
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Istanbul University - Cerrahpasa
Magnetic Resonance Imaging, Major Depression
Ketamine Alcohol (in Treatment-Resistant Depression)
A single subanesthetic dose infusion of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine has rapid and robust antidepressant effects in patients with treatment-refractory major depressive disorder (TRD).
- Conditions
- Magnetic Resonance Imaging, Major Depression, Alcoholism
- Trial name
- NCT02122562
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mark Niciu
Cardiomyopathy, Dilated, Prognosis
Cardiac Magnetic Resonance-Clinical Prediction Model-Dilated Cardiomyopathy
Dilated cardiomyopathy (DCM) is a common and serious heart disease characterized by left ventricular enlargement and impaired pumping function, with adverse prognosis (including heart failure, arrhythmia, heart-related…
- Conditions
- Cardiomyopathy, Dilated, Prognosis, Magnetic Resonance Imaging, Cardiac, Death, Sudden, Cardiac
- Trial name
- MPS-CMR-DCM (NCT07527715)
- Testing
- left ventricular ejection fraction
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Ketoses, Metabolic, Ketogenic Dieting
Effect of Nutritional Ketosis on Alcohol Metabolism
The research study is being conducted in health controls to better understand the effects of ketosis on brain functioning after 3 different, randomly assigned, 3-day dietary interventions and the acute effects of alcohol after…
- Conditions
- Ketoses, Metabolic, Ketogenic Dieting, Alcohol Intoxication, Magnetic Resonance Imaging
- Trial name
- KAM (NCT06065657)
- Testing
- Ketone Supplement, Control Diet, Ketogenic diet
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke, Magnetic Resonance Imaging
Intravoxel Incoherent Motion Prognostic Value in the Initial Evaluation of Patients With Acute Ischemic Strokes Using 3 Tesla Magnetic Resonance Imaging
Ischemic strokes are the first cause of handicap in adult people, the second cause of dementia and the third cause of death in France.
- Trial name
- IMPROVES (NCT03265860)
- Testing
- IntraVoxel Incoherent Motion sequence
- Where
- France
- Volunteers
- 274 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Magnetic Resonance Imaging
Quantitative T1rho Magnetic Resonance Imaging in Healthy Subjects
T1rho imaging is a new MRI technique that has strong potential in neuroimaging. This technique does not require exogenous contrast agents and has high spatial resolution.
- Trial name
- NCT04993196
- Testing
- T1rho imaging
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Transplant, Heart, Magnetic Resonance Imaging
Heart Transplantation - Renewal
Heart transplantation (HTx) is a well-established life-saving procedure but is associated with severe complications. Regular monitoring of heart transplant recipients is thus important for the early detection of these…
- Trial name
- HeartRenewal (NCT05521399)
- Testing
- MRI Sequencing, MRI Testing (pediatric), MRI Testing
- Where
- 2 sites in United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Magnetic Resonance Imaging Sequences
Test and Optimization of New Specific MRI Sequences on an Imager Dedicated to Research
Magnetic Resonance Imaging (MRI) performance depends on equipment performance, equipment maintenance and relevance of MRI sequence used.
- Trial name
- SEQ-IRM (NCT03674645)
- Testing
- MRI acquisitions
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Body Temperature Changes, Pediatric Anesthesia
Temperature Changes During Sedated Pediatric Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is widely used in pediatric patients and frequently requires sedation or general anesthesia. Both sedation and MRI-related environmental factors may influence thermoregulation.
- Conditions
- Body Temperature Changes, Pediatric Anesthesia, Magnetic Resonance Imaging
- Trial name
- NCT07455695
- Testing
- Sedation During MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 285 people
- Sponsor
- Ankara Etlik City Hospital
Magnetic Resonance Imaging
MR Guidance for Liver and Pancreas
This is a single centre, single arm, prospective feasibility study that aims to see whether magnetic resonance imaging (MRI) as a source of image guidance before each radiation treatment fraction is feasible, and also if it may…
- Trial name
- NCT03582189
- Testing
- MRI
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Trigeminal Neuralgia, Trigeminal Nerve Diseases
Artificial Intelligence to Predict Surgical Outcomes and Assess Pain Neuromodulation in Trigeminal Neuralgia Subjects
Trigeminal neuralgia (TN) is the most common cause of facial pain. Medical treatment is the first therapeutic choice whereas surgery, including Gamma Knife radiosurgery (GKRS), is indicated in case of pharmacological therapy…
- Conditions
- Trigeminal Neuralgia, Trigeminal Nerve Diseases, Virtual Reality, Artificial Intelligence
- Trial name
- NCT05810428
- Testing
- GKRS-VR training, Control Group
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Magnetic Resonance Imaging
Validation and Implementation of 3T MRI Research Protocols
The Philips 3T imager installed on the Pavillon Baudot site is an imager dedicated solely to research. It is not located in hospital premises but in INSERM premises for which an authorization for biomedical research has been…
- Trial name
- VALIDIRM (NCT04866940)
- Testing
- Sequences test
- Where
- France
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pancreatic Neoplasm, Magnetic Resonance Imaging
MRE for Diagnosis of Pancreatic Masses
Pancreatic ductal adenocarcinoma (PDAC) accounts for 85-95% of pancreatic cancer and is one of the deadliest tumors in the world, with a survival rate of less than 8%, and identifying key prognostic or predictive factors…
- Trial name
- MREDPCM (NCT06526442)
- Testing
- magnetic resonance imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yu Shi
Conditions Requiring a Brain Magnetic Resonance Imaging, Head Computerized Tomography, or Head Ultrasound
Low Field Magnetic Resonance Imaging Assessment With Outpatients
The objective of the study is to perform imaging assessments of an early stage magnetic resonance imaging (MRI) system on patients using low field magnetic strength.
- Trial name
- NCT05582785
- Testing
- Hyperfine MRI
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Children's Mercy Hospital Kansas City
Cleft Lip and/or Palate, Speech Disorder
Neural Changes After Speech Therapy in Patients With Cleft Palate: A Brain Imaging Study
Cleft palate is one of the most common maxillofacial congenital malformations, which results in severe speech disorders. Compensatory articulation disorder, also known as non-oral articulation disorder (NOA), is considered as the…
- Conditions
- Cleft Lip and/or Palate, Speech Disorder, Speech Therapy, Brain
- Trial name
- fMRI-Speech-CP (NCT07330687)
- Testing
- Structured Speech Training for Decompensation
- Where
- China
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Shufan Zhao
HCM - Hypertrophic Cardiomyopathy, Anderson Fabry Disease
Myocardial Perfusion CMR for Differentiating and Characterizing Hypertrophic Cardiomyopathy Phenotypes
This observational study aims to evaluate myocardial perfusion abnormalities using quantitative and qualitative cardiac magnetic resonance (CMR) perfusion imaging in patients with hypertrophic cardiomyopathy (HCM) phenotypes…
- Conditions
- HCM - Hypertrophic Cardiomyopathy, Anderson Fabry Disease, Cardiac Magnetic Resonance Imaging, Amyloid Cardiomyopathy
- Trial name
- MyoPerf-HCM (NCT07382128)
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna