Clinical trials: Magnetic Resonance
Liver Fibrosis Due to NASH, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Clinical Correlation Evaluation of the LIVERFASt Test for Diagnosing Important Liver Lesions of Fibrosis and Steatosis Against Magnetic Resonance Elastography (MRE) for Liver Fibrosis and MR-based Assessment of Steatosis, in Adult US Population.
This is a retrospective cross-sectional research intended to explore the utility of LIVERFASt in the clinical pathways for the detection of liver fibrosis and steatosis in comparison with the Magnetic Resonance Elastography (MRE)…
- Conditions
- Liver Fibrosis Due to NASH, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Alcohol Liver Disease
- Trial name
- LFMRECT (NCT06797596)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Fibronostics USA, Inc
Primary Progressive Aphasia
HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms
This study aims to evaluate the effectiveness of a therapy called High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for the treatment of the language deficits experienced by people with a type of Primary…
- Trial name
- NCT03805659
- Testing
- HD-tDCS
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical College of Wisconsin
Amnesia, Dementia
Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders
This study is divided into two parts. The first part of the study will use MRI technology to view the brain structure of patients with neurological disorders and normal volunteers.
- Conditions
- Amnesia, Dementia, Healthy, Nervous System Disease
- Trial name
- NCT00001362
- Where
- United States
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Endothelial Dysfunction, Myocardial Perfusion Abnormalities
Cardiac Magnetic Resonance Imaging for Detecting Endothelial Dysfunction
The goal of this research study is to demonstrate that Cardiac Perfusion MRI with Vasomotor Stress may serve as a non-invasive and less risky imaging technique for detecting non-obstructive perfusion deficits and/or abnormalities…
- Conditions
- Endothelial Dysfunction, Myocardial Perfusion Abnormalities, Cardiac MRI Perfusion With Vasomotor Stress, Diabetes
- Trial name
- NCT00808535
- Testing
- Cardiac Perfusion MRI w Vasomotor Stress
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Stroke
Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke
WAKE-UP is an investigator initiated European multicenter randomized controlled clinical trial of MRI based thrombolysis in acute stroke patients with unknown time of symptom onset, e.g.
- Trial name
- WAKE-UP (NCT01525290)
- Testing
- Alteplase
- Where
- 7 sites in Belgium, Denmark and 4 more
- Volunteers
- 501 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hepatoblastoma, Hepatic Hemangioendothelioma
Deep Learning Magnetic Resonance Imaging Radiomics for Diagnostic Value of Hepatic Tumors in Infants
Hepatic tumors in the perinatal period are associated with significant morbidity and mortality in affected patients. The conventional diagnostic tool, such as alpha-fetoprotein (AFP) shows limited value in diagnosis of infantile…
- Trial name
- NCT05170282
- Testing
- Radiomic Algorithm
- Where
- China
- Volunteers
- 200 people
- Sponsor
- West China Hospital
Breast Neoplasms
MRI and Early Decision-making in Chemotherapy for Breast Cancer
Firstly, the investigators aim to show that breast tumour blood flow, measured as part of a standard MRI examination, decreases at the earliest stage of neoadjuvant chemotherapy in those patients who go on to respond to…
- Trial name
- CHERNAC (NCT02449824)
- Testing
- magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Leeds
Healthy, Nervous System Disease
Functional and Metabolic Imaging Using Magnetic Resonance Imaging and Spectroscopy
Technical advances in magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) have provided researchers with the opportunity to study changes of the central nervous system (CNS) and improve diagnosis and…
- Trial name
- NCT00001591
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Dilated Cardiomyopathy, Single-center Study
Cardiac Magnetic Resonance for Risk Stratification in Dilated Cardiomyopathy
Dilated cardiomyopathy (DCM) is an increasingly recognized cause of morbidity and mortality with heterogenous etiologies (eg, genetic, environment) and clinical manifestations, characterized by left ventricular (LV) systolic…
- Trial name
- NCT04990297
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Cancer of the Prostate, Castration-resistant Prostate Cancer
Gadoxetate Sodium Enhanced MRI as a Biomarker for Aggressive Prostate Cancer
The purpose of this research study is to test to see if Gadoxetate Sodium is a useful contrast agent for detecting prostate cancer during magnetic resonance imaging (MRI).
- Trial name
- NCT03960788
- Testing
- Gadoxetate Sodium
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Cincinnati
Healthy
Non-contrast Enhanced Cardiac Magnetic Resonance Normal Values and Imaging Protocols
One of the main problems in cardiac magnetic resonance (MR) investigations is the strong dependence of the achieved image quality on optimal settings of sequence parameters and anatomical and physiological situations and it is…
- Trial name
- CMR-TECH (NCT01728597)
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Healthy
The Effect of Ethanol on Brain Activity
This study is divided into two parts; each designed to answer a separate but related question: Which brain regions are activated in humans by the rewarding properties of ethanol administration? Is it possible to demonstrate a…
- Trial name
- NCT00074360
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
MPS IIIB (Sanfilippo B Syndrome)
Evaluation of Blood Brain Barrier Integrity and Structural Abnormalities in MPS IIIB Patients Using Multimodal Magnetic Resonance Imaging
The purpose of the study is to characterize structural abnormalities in the brain and the integrity of the blood brain barrier in patients with mucopolysaccharidosis type IIIB (MPS IIIB).
- Trial name
- NCT02090179
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Bacteremia
T2 and SeptiCyte RAPID Duration Project
Infection with bacteria and other germs in the blood can be deadly. How long germs stay in the blood is important for two reasons.
- Trial name
- NCT04821661
- Where
- 3 sites in Australia
- Volunteers
- 102 people
- Sponsor
- The University of Queensland
Osteoarthritis, Obesity
Multi-parametric Imaging of the Knee in Obese Patients With Knee Osteoarthritis; Weight Maintenance
This is a substudy to a randomised trial investigating the effect of liraglutide on body weight and pain in overweight or obese patients with knee osteoarthritis (NCT02905864).
- Trial name
- IM-LOSEIT-II (NCT02928679)
- Testing
- Liraglutide 3 mg (Saxenda)
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Henrik Gudbergsen
Glioma, Neoplasms
Study on Neuroepithelial Tumor Grading and Pseudoprogression After Glioma Therapy Using Advanced Functional MRI Techniques
Contrast-enhanced MRI is the most common way for evaluating neuroepithelial tumor grading and monitoring for tumor recurrence,but the ability to predict tumor behavior remains very limited.In this study, the investigators will…
- Trial name
- NCT02622620
- Volunteers
- 86 people
- Sponsor
- Tang-Du Hospital
Schizophrenia, Transcranial Magnetic Stimulation
Personalized Dual-target RTMS for Patients with Refractory Schizophrenia
The goal of this clinical trial is to evaluate the efficacy of personalized dual-target rTMS for treating patients with refractory schizophrenia and to investigate its underlying neural mechanisms using functional MRI.
- Conditions
- Schizophrenia, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- NCT06732817
- Testing
- Active rTMS was administered using a transcranial magnetic stimulator (Rapid2; MagStim).
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Anhui Medical University
Primary Dysmenorrhea
Evaluation of the Effect of TMS on Primary Dysmenorrhea
Based on the pain threshold and visual simulation score, primary dysmenorrhea patients will be divided into treatment effective group or non-effective group.According to the functional magnetic resonance imaging, the…
- Trial name
- NCT04168489
- Testing
- active rTMS
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Osteoarthritis, Knee
An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect
In this proposal, we plan to dynamically investigate brain response to verum acupuncture (of two different "doses") and placebo acupuncture, using a paradigm that approximates clinical acupuncture practice across multiple…
- Trial name
- NCT01079390
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Massachusetts General Hospital
Atherosclerosis
Comparison of Magnetic Resonance Angiography and Standard Angiography in Diagnosing Atherosclerosis
This study will evaluate ways to improve magnetic resonance angiography (MRA) for diagnosing atherosclerosis (hardening and narrowing of the arteries).
- Trial name
- NCT00001946
- Testing
- Magnetic resonance angiography
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
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