Clinical trials: Macular Thickness
Hydration Status, Macular Thickness
Hydration Status and Ocular Parameters Study
This study will examine how hydration status (drinking a large amount of water or avoiding water for a short period of time) affects the eye.
- Conditions
- Hydration Status, Macular Thickness, Ocular Biometry
- Trial name
- HYDRI-EYE (NCT07177131)
- Testing
- Relative Dehydration Protocol, Hyperhydration Protocol
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ante Kreso
Idiopathic Macular Hole, Macular Hole
Intraocular Gas Tamponade for Treatment of Large Idiopathic Macular Holes
The goal of this clinical trial is to evaluate the visual and anatomical outcomes of large (410-1000 μm) full-thickness macular holes repair surgery using perfluoropropane (15% C3F8), sulfur hexafluoride (20% SF6) gas tamponade.
- Conditions
- Idiopathic Macular Hole, Macular Hole, Macular Holes, Full Thickness Macular Hole
- Trial name
- NCT06927544
- Testing
- Pars plana vitrectomy
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- The Filatov Institute of Eye Diseases and Tissue Therapy
Epiretinal Membranes, Retinal Detachment
Subjective Pain Scoring for Subtenonal Anesthesia During Vitrectomy
Subtenonal anesthesia is a well-known technique of local anesthesia for patients undergoing pars plana vitrectomies. It was described to be efficient with respect to anesthesia of the eye and it showed less risks compared to…
- Conditions
- Epiretinal Membranes, Retinal Detachment, Full Thickness Macular Hole
- Trial name
- NCT06830070
- Testing
- subjective pain score assessment
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Full Thickness Macular Hole
Full Thickness Macular Hole; Should it be Handled Subacutely?
Full thickness macular hole, FTMH, is a retinal disease involving the fovea that cause central vision loss, metamorphopsia and central scotoma.
- Trial name
- NCT05828251
- Testing
- Vitrectomy (Sequential phakoemulsification and vitrectomy), Combined phako-vitrectomy, Phako (Sequential phakoemulsification and vitrectomy)
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Full Thickness Macular Hole
Foveal Sparing ILM Peeling With ILM Flap Transposition
Foveal sparing internal limiting membrane (ILM) peeling with ILM flap transposition over the macular hole combines the benefits of foveal sparing ILM peeling with ILM flap techniques.
- Trial name
- NCT05897671
- Testing
- retrospective data analysis
- Where
- Austria
- Volunteers
- 42 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Vitreomacular Traction (VMT), Full-thickness Macular Holes (MH)
Effects of Pneumatic Vitreolysis on Macular Hole
Eyes with vitreomacular traction (VMT) and full-thickness macular holes (MH) will be enrolled into a non-randomized cohort treated with pneumatic vitreolysis (PVL) to determine the proportion with VMT release and MH closure and…
- Trial name
- Protocol AH (NCT03677869)
- Testing
- Intraocular gas (C3F8)
- Where
- 45 sites in United States
- Volunteers
- 36 people
- Sponsor
- Jaeb Center for Health Research
OCT Study RNFL and Macular Thickness
Retinal Nerve Fiber Layer Thickness and Macular Thickness in Myopia, Hyperopia and Emmetropia : An OCT Study
The purpose of this study is to investigate the variability of RNFL and macular thickness between myopia , hyper metropia and emmetropia
- Trial name
- NCT05486741
- Testing
- Optical cehernce tomography
- Volunteers
- 450 people
- Sponsor
- Assiut University
Full Thickness Macular Hole
Inverted Flap Versus Internal Limiting Membrane Peeling in Small Full Thickness Macular Holes
Primary outcome: difference of microperimetry retinal sensitivity after primary vitrectomy for idiopathic full thickness macular holes with inverted flap technique versus internal limiting membrane (ILM) peeling technique…
- Trial name
- NCT04498624
- Testing
- inverted flap, peeling internal limiting membrane (ILM)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Turin, Italy
Retinal Detachment, Full Thickness Macular Hole
Inflammasomes in Cell Death in FTMH, ERM, and RRD
Prospective study evaluating the role of inflammasomes in cell death in retinal detachment, full thickness macular hole, and epiretinal membrane.
- Conditions
- Retinal Detachment, Full Thickness Macular Hole, Epiretinal Membrane
- Trial name
- NCT03332758
- Testing
- Pars plana vitrectomy, External drainage
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Allen C. Ho, MD
Cataract;Macular Thickness
The Variations of Macular Thickness in Juvenile Subjects
It is reported that it takes a period form 22 weeks pregnant to the first 45 months of life for macular region to develop from structural formation to functional integrity.
- Trial name
- NCT02653794
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Sun Yat-sen University
Pregnancy, Retinal Nerve Fiber Layer Thickness
Retinal Nerve Fiber Layer and Macular Thickness Changes During Pregnancy
Purpose: Primary: to prospectively measure Retinal Nerve Fiber Layer (RNFL) and macular thickness changes during pregnancy by Optical coherence tomography Secondary: The effect of pregnancy abnormalities on RNFL and macular…
- Conditions
- Pregnancy, Retinal Nerve Fiber Layer Thickness, Macular Thickness
- Trial name
- NCT02154945
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Stage 2 or 3 Full Thickness Macular Hole
Full Thickness Macular Hole and Internal Limiting Membrane Peeling Study
A macular hole is a fairly common problem in the retina and is an important cause of loss of central vision. The aim of this study is to determine whether, in patients with a stage 2 or 3 full thickness macular hole (FTMH)…
- Trial name
- FILMS (NCT00286507)
- Testing
- Vitrectomy, post hyaloid detachment and gas injection with or without ILM peel.
- Where
- 9 sites in Ireland, United Kingdom
- Volunteers
- 141 people
- Sponsor
- University of Aberdeen
Full Thickness Macular Hole
Protocol for RCT of Posturing in Phacovitrectomy for Full Thickness Macular Hole (FTMH)
The purpose of this study is to determine the effect of postoperative posturing on the outcome of macular hole surgery. Current practice is divided; some individuals are advised to posture face-down for 10 days and others are…
- Trial name
- NCT01020760
- Testing
- Face down posture
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- NHS Greater Glasgow and Clyde
Full Thickness Macular Hole
Pilot Randomised Controlled Trial of Posturing Following Surgery for Full-thickness Macular Hole
This is a pilot randomised controlled trial (RCT) to investigate the effect of postoperative face-down positioning on the outcome of macular hole surgery.
- Trial name
- NCT01226160
- Testing
- Postoperative face-down posturing, Postoperative non-posturing group
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Glaucoma Patient, Glaucoma Suspect Patient
The Performances of Spectral Domain Optical Coherence Tomography (OCT) for Distinguishing Glaucomatous Eyes
The purpose of this study is to evaluate performances of each parameters of spectral domain (Cirrus) optical coherence tomography for distinguishing between normal eyes, glaucoma suspect and glaucomatous eyes
- Conditions
- Glaucoma Patient, Glaucoma Suspect Patient, Normal Population, RNFL Thickness by Location
- Trial name
- cirrusOCT (NCT01067482)
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University