Clinical trials: Lung Recruitment
Postoperative Complications, Abdominal Surgery
Intraoperative Lung Protective Ventilation Needs Periodic Lung Recruitment Maneuvers
Postoperative Pulmonary Complications (PPC) are common. It severely affects postoperative recovery, particularly in abdominal surgery.
- Conditions
- Postoperative Complications, Abdominal Surgery, Intraoperative Mechanical Ventilation
- Trial name
- REMAIN-1 (NCT05556174)
- Testing
- periodic lung recruitment maneuvers
- Where
- China
- Volunteers
- 1,060 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Shoulder Pain, Laparoscopic Surgery
Reducing Shoulder Tip Pain Following Laparoscopic Surgery
Laparoscopic surgery is becoming a major procedure, owing to smaller incisions, shorter hospitalizations, and less post-operative pain as compared with traditional laparotomies.
- Trial name
- NCT01135836
- Testing
- Pulmonary recruitment maneuver, Intraperitoneal normal saline, Control group
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Surgery, Pain
Evaluation of the Interest of the Instillation of Saline Intraperitoneally (INSI ) Versus Instillation of Naropin the Surgical Site Versus Lung Recruitment Maneuvers ( PVM ) in the Management of Pain After Laparoscopic Cholecystectomy in Ambulatory Care
Known to reduce analgesics and length of hospitalization in conventional surgery, laparoscopy is characterized by frequent post-operative pain and can decrease the patient's quality of immediate postoperative life and sometimes…
- Trial name
- VSD (NCT02819544)
- Testing
- Sodium chloride administration, Ropivacaine administration
- Where
- 2 sites in France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Bariatric Surgery Candidate
Effects of Alveolar Recruitment Strategies on Arterial Oxygenation and Postoperative Inflammatory Response During Laparoscopic Bariatric Surgery: A Randomised Control Trial.
even though the advancement of ambulatory bariatric surgeries, yet the precise spot of recruitment manoeuvres as a secure and efficient approach to enhance the respiratory efficacy of obese patients is still obscured.
- Trial name
- NCT05960071
- Testing
- protective lung strategy with recruitment manoeuvre (RM) - steady PEEP, protective lung strategy with recruitment manoeuvre (RM) - decreasing PEEP
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Atelectasis, Compliance, Patient
Restoration of Pulmonary Compliance After Laparoscopic Gynaecologic Surgery Using a Recruitment Maneuver
To investigate the hypothesis that an alveolar recruitment maneuver after the release of pneumoperitoneum would restore the lung compliance to the baseline values after a laparoscopic gynaecologic surgery.
- Trial name
- NCT06203665
- Testing
- Recruitment Maneuver
- Where
- Greece
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Panagiota Griva
ARDS, Pediatric Respiratory Distress Syndrome
REcruitment MAneuvers and Mechanical Ventilation Guided by EIT in pARDS
There is evidence from randomized controlled trials in adult patients with Acute Respiratory Distress Syndrome (ARDS) suggesting that delivering small tidal volumes with adequate levels of Positive End-Expiratory Pressure (PEEP)…
- Conditions
- ARDS, Pediatric Respiratory Distress Syndrome, Respiratory Disease
- Trial name
- REMAV-EIT (NCT06067152)
- Testing
- EIT measurement, Staircase Recruitment Maneuvers with EIT guided and decremental PEEP trial, Setting of EIT-guided mechanical ventilation
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Surfactant Deficiency Syndrome Neonatal
deMISTify: The Impact of Ventilator Pressure Levels During Minimally Invasive Surfactant Therapy on Lung Aeration in Preterm Infants
Infants born preterm (before 36 weeks' gestation age) have immature lungs and struggle to breathe on their own. They are supported via respiratory machines like ventilators, as well as pharmaceutical aids like surfactant…
- Trial name
- deMISTify (NCT07522346)
- Testing
- Lung Recruitment Manoeuvre prior to Minimally Invasive Surfactant Therapy, Control (Minimally Invasive Surfactant Therapy)
- Where
- Australia
- Volunteers
- 36 people
- Sponsor
- Murdoch Childrens Research Institute
Acute Respiratory Distress Syndrome
How to Predict Lung Recruitment at the Bedside in Patients Affected by Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS)
The investigators aim to compare four different lung recruitment techniques (described in literature) to Computed tomography scan analysis.
- Trial name
- NCT00682942
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Policlinico Hospital
Acute Respiratory Distress Syndrome
EIT- Guided Lung Recruitment in pARDS
Study Title: EIT-Guided Lung Recruitment Maneuvers in Pediatric ARDS: Effects on Ventilation Distribution and Respiratory Mechanics Study Objective: The primary goal of this clinical trial is to determine whether lung recruitment…
- Trial name
- REMAV-EIT (NCT07402174)
- Testing
- Electrical Impedance Tomography (EIT)-Guided Lung Recruitment
- Where
- 2 sites in Italy
- Volunteers
- 8 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Mechanical Ventilation Complication, Postoperative Pulmonary Atelectasis
Perioperative Mechanical Ventilation and Postoperative Monitoring of IPI
This study evaluates the influence of alveolar recruitment maneuver, protocolized liberation from respiratory support and monitoring of Integrated Pulmonary Index on the duration of the mechanical ventilation and the number of…
- Trial name
- WEAN-IPI (NCT02524522)
- Testing
- INTELLiVENT-ASV mode, SIMV mode
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Northern State Medical University
Recruitment
Effects of Two Different Stepwise Lung Recruitment Maneuvers on Patient Hemodynamics During Laproscopic Surgery
Pneumoperitoneum with CO2 insufflation during laparoscopic surgery elevates the intrathoracic pressure through the elevation of the diaphragm, which in turn decreases the lung compliance .Alveolar recruitment (AR) refers to the…
- Trial name
- NCT04082377
- Testing
- Recruitment maneuver with tidal volume (RM TV), Recruitment maneuver by PEEP (RM PEEP)
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Acute Respiratory Distress Syndrome, Acute Lung Injury
Comparison of Two Methods to Estimate the Lung Recruitment
In this study the investigators aim to compare two common methods to estimate the lung recruitment in ALI/ARDS patients.
- Trial name
- NCT00759590
- Testing
- CT scan and Pressure volume curve
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Policlinico Hospital
Cardiac Output, Hemodynamic Optimization
Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers - ICU Patients
The objective of this study was to investigate the hemodynamic effects of two alveolar recruitment maneuver strategies in critical care patients with acute respiratory distress syndrome.
- Conditions
- Cardiac Output, Hemodynamic Optimization, Monitoring Blood Pressure, Stroke Volume
- Trial name
- CHARM-ICU (NCT05365854)
- Testing
- Alveolar Recruitment Maneuver (ARM)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Atelectasis
Lung Recruitment Assessment With Lung Ultrasound In Pediatric Patient Scheduled For Laparoscopic Surgery
Anesthesia-induced atelectasis is a well-known entity observed in approximately 68-100% of pediatric patients undergoing general anesthesia.
- Trial name
- NCT02824146
- Testing
- Lung recruitment maneuver
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Atelectasis, Postoperative Complications
Ultrasound-guided Lung Recruitment Maneuvers for Postoperative Pediatric Atelectasis
In anesthetized children, the incidence of lung collapse with episodes of hypoxemia is high. Diaphragmatic dysfunction induced by general anesthesia is one of the most important factors in the genesis of regional losses of lung…
- Conditions
- Atelectasis, Postoperative Complications, Recruitment, Pediatric
- Trial name
- NCT05777018
- Testing
- conventional recruitment maneuvers, ultrasound-guided recruitment maneuvers
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
ARDS (Acute Respiratory Distress Syndrome)
Influence of Lung Recruitment Potential on Positive End-Expiratory Pressure (PEEP) Titration Strategies in Acute Respiratory Distress Syndrome (ARDS) Patients.
Acute Respiratory Distress Syndrome (ARDS) is characterized by severe hypoxemia and diffuse alveolar collapse, often requiring invasive mechanical ventilation.
- Trial name
- RECRUIT-PEEP (NCT07603310)
- Testing
- Positive End-Expiratory Pressure (PEEP) Titration guided by Static Compliance, Positive End-Expiratory Pressure (PEEP) Titration guided by Transpulmonary Pressure
- Where
- Chile
- Volunteers
- 52 people
- Sponsor
- Hospital Dr. Franco Ravera Zunino
Asthma
Study of the Inflammation and Airway Changes That Occur After Exposure to Allergen in Asthmatics
This protocol describes a single site mechanistic study to investigate microRNAs (miRNAs) that are differentially expressed in the airway epithelium of patients with asthma at baseline and in response to allergen challenge.
- Trial name
- ACE (NCT02230189)
- Testing
- Segmental airway allergen challenge, Bronchoscopy, Methacholine challenge test
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Prescott Woodruff
Lung Cancer
Multinational Observational Study to Describe Diagnostic Stage Shift in Patients With Lung Cancer Using Medical Records
Multinational observational study to describe diagnostic stage shift in patients with lung cancer using medical records. Increased lung cancer screening programs and increased utilization of other screening modalities such as…
- Trial name
- DIASTAG (NCT06842056)
- Volunteers
- 3,000 people
- Sponsor
- AstraZeneca
Postoperative Pulmonary Atelectasis, Negative Pressure Therapy
Evaluation of the Effect of Novel Recruitment Maneuver Therapy for Postoperative Pulmonary Atelectasis
1. Oxygenation index and bedside ultrasound would be used to evaluate the therapeutic effect of novel recruitment maneuver therapy in the patients with pulmonary atelectasis after cardiac surgery. 2.
- Trial name
- NCT06049173
- Testing
- Negative extra-abdominal pressure (NEXAP)-based lung recruitment maneuver, stepwise positive end-expiratory pressure (PEEP)-based lung recruitment maneuver
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Jilai Xiao
Perioperative Complication, Hypoxia
Prevention of Perioperative Pulmonary Complications by Lung Recruitment During Laparoscopic Surgery
Perioperative pulmonary complications such as atelectasis, hypoxemia, and pneumonia after ventilatory management during general anesthesia have a negative impact on patient outcomes.
- Trial name
- NCT04728945
- Testing
- lung recruitment, Standard ventilatory management
- Where
- Japan
- Volunteers
- 80 people
- Sponsor
- Osaka University