Clinical trials: Lung Nodules
Neoplastic Disease, Solid Tumor
Indocyanine Green (ICG) Guided Tumor Resection
This is a study to assess the ability of Indocyanine Green (ICG) to identify neoplastic disease. For many pediatric solid tumors, complete resection of the primary site and/or metastatic deposits is critical for achieving a cure.
- Trial name
- NCT04084067
- Testing
- Indocyanine Green
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- St. Jude Children's Research Hospital
Lung Cancer, Pulmonary Nodule
A Retrospective Multicenter Review to Evaluate the Performance of the Ion Endoluminal System in Sampling Pulmonary Lesions
This study is a retrospective multi-center chart review of patients who underwent an attempted biopsy of one or more pulmonary lesion(s) with the Ion Endoluminal System with the aim of assessing the overall performance of the…
- Trial name
- NCT05160571
- Testing
- Ion Endoluminal System
- Where
- United States
- Volunteers
- 279 people
- Sponsor
- Intuitive Surgical
Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery
Video-guided Versus Conventional Right-sided Double-lumen Tube Placement for Thoracoscopic Surgery
Right-sided double-lumen tubes are used for lung isolation during thoracoscopic surgery but can be difficult to position because of right bronchial anatomy.
- Conditions
- Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery, One-lung Ventilation, Lung Cancer
- Trial name
- NCT07849400
- Testing
- Continuous video-guided right-sided double-lumen tube, Conventional right-sided double-lumen tube
- Where
- 3 sites in China
- Volunteers
- 566 people
- Sponsor
- Diansan Su
COPD, Lung Cancers
Assessment the Effectiveness of BTVA in COPD and Ablation in Pulmonary Nodules by Pulmonary MRI
A Clinical Study Based on Magnetic Resonance Imaging of the Lungs to Assess the Efficacy of Thermal Vapor Ablation and Pulmonary Nodule Ablation in Chronic Obstructive Pulmonary Disease After Surgery.
- Trial name
- NCT07045532
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Chest Hospital
Pulmonary Nodule, Pneumothorax
Safety And Recovery Of Tubeless Strategy In Uniportal VATS Wedge Resection
Brief Summary The goal of this clinical trial is to evaluate the safety and recovery outcomes of different tubeless strategies in adult patients undergoing uniportal video-assisted thoracoscopic (VATS) wedge resection who are…
- Conditions
- Pulmonary Nodule, Pneumothorax, Postoperative Complications
- Trial name
- NCT07395349
- Testing
- Conventional Chest Tube Drainage, Single Intraoperative Aspiration Tubeless, Double Intraoperative Aspiration Tubeless
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Lung Nodule
AI-based Low Dose CBCT Reconstruction for Clinical Application
The goal of this clinical trial is to learn if AI-based low dose CBCT reconstructed images can guide lung puncture effectively. The main questions it aims to answer are: 1.
- Trial name
- NCT06831617
- Testing
- AI-based low dose CBCT reconstructed images system, Conventional CBCT images system
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Non-small Cell Lung Cancer
Electromagnetic Navigational Bronchoscopy Vs. Transthoracic Needle Biopsy for the Sampling of Peripheral Lung Nodules
The use of computed tomography (CT) screening has allowed for early detection of lung cancers as small as 5mm in diameter. Early stage cancers are highly curable with a reported survival of greater than 90% over 5 years after…
- Trial name
- NCT02651506
- Testing
- Electromagnetic Navigation Bronchoscopy, Transthoracic Needle Biopsy
- Sponsor
- St. Joseph's Healthcare Hamilton
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Teachable Moment to Opt-out of Tobacco: Interactive Voice Response Quit Line for Veteran Active Smokers With Lung Nodules
The purpose of this study is to evaluate the effectiveness of a smoking cessation outreach intervention (TeaM OUT) on increasing use of smoking cessation resources in Veterans.
- Conditions
- Solitary Pulmonary Nodule, Multiple Pulmonary Nodules, Tobacco Use
- Trial name
- TeaMOUT (NCT04574518)
- Testing
- TeaM OUT Intervention, Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 223 people
- Sponsor
- VA Office of Research and Development
Pulmonary Nodules, Early-Stage Lung Cancer
Application of Electromagnetic Navigation System in Pulmonary Nodule Localization
This study aims to design and conduct a multicenter, prospective, randomized controlled post-market clinical trial to validate the clinical efficacy of high-precision electromagnetic navigation technology.
- Trial name
- NCT07595120
- Testing
- Electromagnetic Navigation-Guided Percutaneous Localization of Pulmonary Nodules, CT-Guided Percutaneous Localization of Pulmonary Nodules
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Suture, Nodule, Solitary Pulmonary
Semi-barbed Suture for Pulmonary Small Nodules Localization
Hookwire and microcoil are currently the most widely used localization instruments. Although their success rate is relatively high in preoperative localization attempts, they may lead to consequences that negatively affect…
- Conditions
- Suture, Nodule, Solitary Pulmonary, Video-Assisted Thoracoscopic Surgery
- Trial name
- NCT04168359
- Testing
- absorbable semi-barbed suture
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Aerospace General Hospital
Lung Cancer
Respiration Gated Laser Guided CT Lung Nodule Biopsy
The primary outcome of this study is to investigate the accuracy of respiration gated laser guided CT lung nodule biopsy through a prospective randomized trial using a bellows-based breath hold monitoring system.
- Trial name
- GENCTBIOPSY (NCT01236937)
- Testing
- Bellows-based breath hold device
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Lung Abscess
Biomarkers for Diagnosis of Lung Nodules
A need exists for non-invasive testing to aid in clinical decision-making for Computerized Tomography (CT) scan detected lung nodules of indeterminate etiology.
- Trial name
- Nodule (NCT01085864)
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- University of Colorado, Denver
Early-Stage Lung Cancer, NSCLC
A Study Developing a Non-invasive Urine-based Proteomic Model for Early Lung Cancer Detection.
Brief Summary: The goal of this observational study is to develop a non-invasive urine proteomic diagnostic model to improve early-stage lung cancer detection.
- Conditions
- Early-Stage Lung Cancer, NSCLC, Pulmonary Nodule
- Trial name
- UPD-LC (NCT06733311)
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Beijing Chao Yang Hospital
Pulmonary Nodule
Augmented Reality Navigation Versus Traditional CT Guidance for Preoperative Localization of Pulmonary Nodules
This study aims to conduct a large-sample randomized controlled clinical trial, using traditional CT-guided thoracic puncture localization as a comparison, to explore the accuracy, safety and clinical advantages of Intelligent AR…
- Trial name
- NCT06335563
- Testing
- AR glasses-assisted pulmonary nodule puncture localization, CT-guided pulmonary nodule puncture localization
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Cancer of the Lung, Lung Cancer
Circulating Tumor DNA in Patients at High Risk for Lung Cancer
Patients who are about to undergo a diagnostic or therapeutic bronchoscopy or thoracic surgery without a distant history of cancer will have their blood drawn for measurement of circulating tumor DNA (ctDNA) to validate the…
- Conditions
- Cancer of the Lung, Lung Cancer, Lung Neoplasms, Adenocarcinoma of the Lung
- Trial name
- NCT02715102
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Pathway Genomics
Pulmonary Nodules, Lung Neoplasms
A Multicenter Cohort Study of AI-Based Methods for Pulmonary Nodule Diagnosis and Follow-up
This is an observational, multicentre study. The primary objective of this study was to evaluate the diagnostic performance and clinical applicability of artificial intelligence models for pulmonary nodule segmentation…
- Conditions
- Pulmonary Nodules, Lung Neoplasms, Artificial Intelligence (AI)
- Trial name
- NCT07815483
- Volunteers
- 16,880 people
- Sponsor
- Shanghai East Hospital
Multiple Pulmonary Nodules
Fast Track Rehabilitation Following Video-assisted Lung Segmentectomy
Aim of this prospective randomized study is to assess the safety and efficacy of video-assisted lung segmentectomy (Group B) comparing with mini muscle-sparing thoracotomy (group A) during diagnostic process for pulmonary nodules.
- Trial name
- NCT01397045
- Testing
- VATS, Mini thoracotomy
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Theagenio Cancer Hospital
Pulmonary Infection, Pulmonary Nodule
COMBO Endoscopy Oropharyngeal Airway in Sedated Fiberoptic Bronchoscopy for Patients: A Simon Two-Stage Trial
Hypoxia represents the prevailing adverse occurrence during the sedation of patients undergoing fiberoptic bronchoscopy with propofol.
- Conditions
- Pulmonary Infection, Pulmonary Nodule, Endotracheal Tumour, Bronchiectasis
- Trial name
- NCT07063290
- Testing
- the COMBO Endoscopy Oropharyngeal Airway
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Zhejiang University
Moderate Persistent Asthma, Severe Persistent Asthma
Expressions of TRPV1 in Airway of Asthmatics
The purpose of this study is to measure the density of a temperature-sensitive protein, named TRPV1, in the airway mucosa tissue of both non-asthmatic and moderate to severe persistent asthmatic patients.
- Conditions
- Moderate Persistent Asthma, Severe Persistent Asthma, Nodule Solitary Pulmonary, Pulmonary Atelectasis
- Trial name
- TRPV1 (NCT02952066)
- Testing
- Bronchial biopsy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lu Yuan Lee
Tumor
Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors
This is a study to assess the combination of PXD101 and 5-Fluorouracil (5-FU)in patients with advanced solid tumors. The primary goal of the study is to understand the safety, anti-tumor activity, and how the study drug behaves…
- Trial name
- NCT00413322
- Testing
- belinostat, 5-Fluorouracil (5-FU)
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- Valerio Therapeutics