Clinical trials: Lung Function
COPD
Differential Trough Effects of 'Triple Therapy' on Pulmonary Function in Chronic Obstructive Pulmonary Disease (COPD)
Different medications are often used in combination for the condition COPD (chronic obstructive pulmonary disease). Some medicines act by opening the airways (bronchodilators) and some act as anti-inflammatories (steroids).
- Trial name
- FARD12 (NCT00996697)
- Testing
- Budesonide/formoterol and tiotropium
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Brian J Lipworth
Stable COPD Patients
Study on the Mechanism of Yifei Moxibustion Improving Immune Function in COPD Based on Plasma Exosome miRNAs
This study adopted a randomized controlled design, enrolling 90 patients and 30 healthy volunteers. The patients were randomly divided into the Yifei Moxibustion group, the conventional Western medicine treatment group, and the…
- Trial name
- NCT07131020
- Testing
- Yifei moxibustion, Conventional Western medicine treatment, TCM syndrome differentiation treatment
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Henan University of Traditional Chinese Medicine
Lung Cancer
A Novel Lung Function Imaging Modality As a Preoperative Evaluation Tool (LIME)
To evaluate the correlation between pre-surgical 4DCT-ventilation imaging and post-surgical lung function.
- Trial name
- NCT03426306
- Testing
- 4DCT-Ventilation
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of Colorado, Denver
Asthma, COPD
The Mixed Phenotype of Asthma and COPD: the Overlap Syndrome
RATIONALE: In asthmatic subjects, smoking can lead to several changes in disease characterictics. in smokers of more than 20 pack-years, chronic obstructive pulmonary disease (COPD) can be associated with asthma, also called…
- Trial name
- NCT03817333
- Where
- Canada
- Volunteers
- 115 people
- Sponsor
- Laval University
Lung Transplantation
Impact of Inspiratory Muscle Training (IMT) With Intermittent Variable Resistance (IVR) Versus Constant Resistance (CR) on Functional Capacity in Lung Transplantation (LTx) Patients (I-TRAIN-LTx Study)
Objectives: Primary Objective: To compare Maximum Inspiratory Pressure (MIP) in lung transplant (LT) patients between the use of inspiratory muscle training (IMT) with intermittent variable resistance (IVR) or constant resistance…
- Trial name
- I-TRAIN-LTx (NCT06963190)
- Testing
- Constant Resistance (CR), Intermittent Variable Resistance (IVR)
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitario Marqués de Valdecilla
Exposure to Electronic Cigarettes
Changes in Psychological and Somatic Parameters Associated With Changing From Smoking to E-cigarettes
The purpose of this study is to investigate whether changing from conventional smoking to electronic cigarettes causes changes in conventional lung function parameters, bronchial reactivity, fractional exhaled nitric oxide…
- Trial name
- EQualLife (NCT02635620)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Lung Cancer (Diagnosis)
The Effects of Low Intensity Endurance Exercise on Improving Mitochondrial Function, Cell Bioelectrical Impedance Phase Angle, Fatigue and Quality of Life in Lung Cancer Patients With Cancer-related Fatigue
To conduct a randomized controlled trial (RCT) targeting lung cancer patients with cancer-related fatigue to achieve the following objectives: Objective 1: To investigate whether a low-intensity endurance exercise intervention…
- Trial name
- NCT07806682
- Testing
- Low-Intensity Endurance Continuous Exercise, Low-Intensity Endurance Interval Exercise
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Taipei Medical University
Pulmonary Hypertension
Mobile Internet-based Remote Home Rehabilitation Improves Prognostic Function and Life Quality in Pulmonary Hypertension
The goal of this clinical trial is to learn the effectiveness of remote home-based exercise rehabilitation using mobile Internet technology for patients with pulmonary hypertension，especically providing early and mid-term results…
- Trial name
- NCT06362382
- Testing
- tele-rehabilitation training, health propaganda and education
- Where
- China
- Volunteers
- 80 people
- Sponsor
- China-Japan Friendship Hospital
Neck Pain
The Effects of Two Different Home-exercise Programmes on Women Suffering Long Term Neck/Shoulder Muscle Pain
The purpose of this study is to investigate the effects of specific neck/shoulder muscle exercises on pain, function, biochemistry and psychological factors in women suffering chronic neck/shoulder pain.
- Trial name
- NCT01876680
- Testing
- Stretching and aerobic exercise, Strength training
- Where
- Sweden
- Volunteers
- 57 people
- Sponsor
- Linkoeping University
Lung Diseases
Pressure-controlled vs Volume Controlled Ventilation on RV Function During OLV
The use of pressure controlled ventilation (TV) during one lung ventilation (OLV) for thoracic surgery is associated with comparable oxygenation with volume controlled ventilation (VCV) with added benefits of decreasing airway…
- Trial name
- NCT01763879
- Testing
- The PCV-VCV group, The VCV-PCV group
- Where
- Saudi Arabia
- Volunteers
- 28 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
COPD
PulseHaler Drug Deposition Study in Chronic Obstructive Pulmonary Disease Patients
This study is aimed at finding the effect of PulseHaler™ with Albuterol on Lung Deposition of Aerosol and on Pulmonary Functions in COPD Patients
- Trial name
- NCT01187589
- Testing
- Pulsehaler, Nebulizer & Albuterol 0.5ml
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Respinova LTD
Asthma Acute, Asthma in Children
User-Friendly Spirometer and Mobile App for Self-Management and Home Monitoring of Asthma Patients
The primary goal of this proposal is to use an in-home, smartphone-enabled, hand-held spirometer to determine the FEV1% predicted ranges that predict the Yellow Zone threshold.
- Conditions
- Asthma Acute, Asthma in Children, Asthma Chronic, Asthma Attack
- Trial name
- NCT03642418
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Asthma
Functional Activity of Airway Eosinophils in Allergic Disease
The purpose of this study is to determine how a special white blood cell, the eosinophil, can contribute to asthma. One of the characteristics of asthma is airway inflammation.
- Trial name
- NCT01026532
- Testing
- Segmental Allergen Challenge
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison
Right Ventricular Dysfunction
Right Ventricular Contractility Reserve Following Repair of Tetralogy of Fallot
Background: Residual pulmonary regurgitation following repair of tetralogy of Fallot, in particular the use of a transannular patch, has been shown to correlate with the development of right ventricular dysfunction.
- Trial name
- TOF-Cond (NCT00557934)
- Testing
- dobutamine
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- University Hospital Tuebingen
Airway Obstruction, Asthma
Effects of Combined Respiratory Muscle Training and Steam Inhalation
The purpose of this investigation is to obtain more information on the efficacy and safety of respiratory training methods with WellO2 in patients with asthma and COPD.
- Conditions
- Airway Obstruction, Asthma, COPD
- Trial name
- NCT04584398
- Testing
- Respiratory muscle training with steam inhalation
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- WellO2 Oy
Copd
Sonographic Diaphragm Function in AECOPD
The study will be conducted as a single-center, prospective cohort study. The primary objective of this study is to investigate the responsiveness of sonographic parameters of diaphragm to detect change in Borg score for dyspnea…
- Trial name
- UNDATED (NCT05671198)
- Testing
- Ultrasound of the diaphragm
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Isala
Metastatic Melanoma
Ipilimumab-induced Lung Toxicity: Observational Study
Serial spirometries and measurements of CO-diffusion capacity (DLCO) in patients with MM before and during treatment with ipilimumab are performed.
- Trial name
- Ipi-Lu-Tox (NCT02755233)
- Testing
- Pulmonary Function
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- University of Zurich
Quality of Lifte, Cystic Fibrosis (CF)
Characterisation of a Population of Adults Suffering From Cystic Fibrosis in a Belgian Reference Center
This research project aims to better understand the consequences of diabetes on the quality of life, respiratory function, and nutritional status of patients with cystic fibrosis followed at a Belgian reference center and to…
- Conditions
- Quality of Lifte, Cystic Fibrosis (CF), Diabetes
- Trial name
- NCT07442682
- Where
- Belgium
- Volunteers
- 162 people
- Sponsor
- Erasme University Hospital
COVID-19, Lung Function Decreased
Pulmonary Function and CT Scan Finding in CKD Patients After COVID-19 Infection
COVID-19 is associated with increased morbidity and mortality in patients with chronic kidney disease (CKD) on dialysis. CKD requires particular emphasis during the pandemic due to concern for increased susceptibility to…
- Conditions
- COVID-19, Lung Function Decreased, Xray Complication
- Trial name
- NCT05348759
- Testing
- Pulmonary function test, Chest computer scan
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
COPD, Obstructive Ventilation Disorder
Evaluation of Novel Lung Function Parameters in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Current guideline-based criteria defining COPD do not meet the challenges set by the complex pathophysiology of the disease. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the…
- Conditions
- COPD, Obstructive Ventilation Disorder, Pulmonary Emphysema
- Trial name
- NCT02827721
- Testing
- impulse oscillometry, multiple breath washout test, body plethysmography
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim