Clinical trials: Lumbar Disc Herniation, open to volunteers
Lumbar Disc Herniation With Radiculopathy, Sciatica
FINDISC-Pain, Finnish Discectomy Trial on the Benefits and Harms of Surgery in Patients With Lumbar Disc Herniation
The FINDISC trial studies whether common back operation, microdiscectomy, is effective and safe for treating sciatica caused by a lumbar disc herniation.
- Trial name
- FINDISC-Pain (NCT07418944)
- Testing
- Microdiscectomy
- Where
- Finland
- Volunteers
- 122 people
- Sponsor
- Helsinki University Central Hospital
Sciatica, Lumbar Disc Herniation
Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial
The goal of this clinical trial is to learn if electroacupuncture can improve sleep in people with chronic sciatica caused by lumbar disc herniation. It will also assess the safety of this treatment.
- Conditions
- Sciatica, Lumbar Disc Herniation, Insomnia
- Trial name
- NCT07576348
- Testing
- Electroacupuncture
- Volunteers
- 114 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Lumbar Disc Herniation, Lumbar Disc Disease
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
The purpose of this study is to determine the optimal anesthetic routine for lumbar decompression surgery. General Anesthesia is the standard of care in spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
- Trial name
- NCT05444751
- Testing
- General anesthetic, SA + ESP
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Lumbar Disc Herniation, Obstructive Sleep Apnea Risk Management
Daytime vs Evening Rehabilitation in Lumbar Disc Herniation Patients at High Risk for Obstructive Sleep Apnea
Lumbar disc herniation is a common musculoskeletal condition that negatively affects quality of life, physical function, and daily activities.
- Trial name
- REHAB-TIME (NCT07522021)
- Testing
- Physiotherapy and Exercise Program
- Volunteers
- 60 people
- Sponsor
- Mardin Artuklu University
Lumbar Disc Disease, Low Back Pain
Clinical and MRI Findings in Lumbar Disc Disease
Low back pain related to lumbar disc disease is a very common condition. Doctors frequently use Magnetic Resonance Imaging (MRI) to look at the spine and diagnose these problems.
- Conditions
- Lumbar Disc Disease, Low Back Pain, Lumbar Disc Herniation, Lumbosacral Radiculopathy
- Trial name
- NCT07516613
- Volunteers
- 96 people
- Sponsor
- Assiut University
Vibration, Lumbar Disc Herniation
IASTM and Vibration Effects on Pain, Functionality, and Kinesiophobia in Lumbar Disc Herniation
The aim of this study is to investigate the effects of Instrument-Assisted Soft Tissue Mobilization and vibration massage therapy on pain, functionality, and kinesiophobia in individuals with lumbar disc herniation.
- Conditions
- Vibration, Lumbar Disc Herniation, Soft Tissue Mobilization
- Trial name
- NCT07293676
- Testing
- Exercise, IASTM, Percussion massage therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Lumbar Spinal Stenosis, Lumbar Disc Herniation With Radiculopathy
Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery
This prospective, observational, non-randomized clinical study aims to evaluate the intraoperative and postoperative effects of opioid-free multimodal anesthesia compared with opioid-containing anesthesia methods in adult…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation With Radiculopathy, Lumbar Degenerative Spondylolisthesis, Lumbar Disc Degeneration
- Trial name
- NCT07489001
- Testing
- Opioid-free Anesthesia, Erector Spinae Plane Block, Opioid based Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Marmara University
Lumbar Disc Herniation, Preoperative Anxiety
Comparison of Virtual Reality-Based and Routine Preoperative Education on Surgical Anxiety and Salivary Cortisol
This randomized controlled pilot study aims to compare the effects of virtual reality-based preoperative education and routine preoperative education on surgical anxiety in patients undergoing lumbar disc surgery.
- Trial name
- NCT07443111
- Testing
- Virtual Reality-Based Preoperative Education, Routine Preoperative Education
- Volunteers
- 56 people
- Sponsor
- Bezmialem Vakif University
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis
- Trial name
- NCT05029726
- Testing
- Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- John O'Toole
Motor Deficits, Lumbar Discectomy
Investigation of Preoperative Factors Influencing the Outcome of Motor Deficits in Patients Undergoing Lumbar Microdiskectomy
Lumbar disc herniations may result in lower limb weakness. In such cases, there is a strong indication for surgical intervention through microdiscectomy.
- Conditions
- Motor Deficits, Lumbar Discectomy, Muscle Weakness, Paresis
- Trial name
- NCT07413302
- Where
- 3 sites in Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
Lumbar Disc Herniation, Lumbar Radiculopathy
PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation
This prospective observational study aims to evaluate the clinical outcomes of patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD).
- Trial name
- PLDD-TFESI (NCT07400068)
- Testing
- Percutaneous Laser Disc Decompression (PLDD), Transforaminal Anterior Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Mersin University
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Lumbar Disc Herniation
Evaluation of the Effectiveness of Focused Radiofrequency (TECAR) Therapy on Pain, Disability, Function, and Quality of Life in Patients With Lumbar Disc Herniation
Low back pain is a very common health problem in societies, regardless of the underlying cause. Its lifetime prevalence has been reported to be as high as 75-80%.
- Trial name
- TECAR THERAPY (NCT07335718)
- Testing
- TECAR THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara City Hospital Bilkent
Disc Herniation, Disk Herniated Lumbar
Safety And Performance Of Disc Care To Prevent Lumbar Disc Herniation Recurrence
The goal of this clinical investigation is to learn about DISC Care, an Hernia Blocking System, in patients who have undergone lumbar disc hernia surgery.
- Trial name
- ACE-2 (NCT06023719)
- Testing
- DISC Care
- Where
- 7 sites in Spain
- Volunteers
- 30 people
- Sponsor
- NEOS Surgery
Disc Herniations, Disc Herniation, Lumbar
Smartwatch Accuracy for Measuring Vitals and Anxiety Before Disc Surgery
This study aims to verify the accuracy of blood pressure, heart rate, blood oxygen saturation, anxiety level, and sleep cycle data measurements obtained from Samsung smartwatches compared to the currently accepted method used in…
- Conditions
- Disc Herniations, Disc Herniation, Lumbar, Cervical Disc Herniation, Preoperative Anxiety Score
- Trial name
- NCT07322523
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Halil Kalaycı
Lumbar Disc Herniation
Comparison Between Insertion of Bilateral Straight Cages Versus Unilateral Banana Cage in Lumbar Fusion Surgery
To compare the clinical outcomes of bilateral straight cages and unilateral banana cage insertion in lumbar interbody fusion surgery, assess radiological outcomes, including intervertebral disc height, lumbar lordosis angle, and…
- Trial name
- NCT07312747
- Testing
- cages in lumbar fusion surgery
- Volunteers
- 30 people
- Sponsor
- Assiut University
Adult Spinal Deformity, Degenerative Scoliosis
Gait and Paraspinal sEMG in Degenerative Spinal Diseases
This cross-sectional observational study aims to quantitatively compare three-dimensional gait parameters, surface electromyography (EMG) patterns, and radiological parameters among patients with different degenerative spinal…
- Conditions
- Adult Spinal Deformity, Degenerative Scoliosis, Sagittal Deformity, Sagittal Imbalance
- Trial name
- TDGKSEPDSD (NCT07309926)
- Testing
- Gait analysis and surface electromyography analysis
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Lumbar Intervertebral Disc Herniation
A Randomized Trial of Annular Repair With Discectomy Versus Discectomy Alone for Lumbar Disc Herniation
The goal of this study is to explore the indications and application scope of spinal endoscopy combined with annulus fibrosus repair technology, with a focus on verifying the effectiveness of annulus fibrosus suture technology…
- Trial name
- NCT07250581
- Testing
- Repair of the annulus fibrosus
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Lumbar Disc Herniation, Surgery
The Effect of Ney Music on Patients Undergoing Lumbar Disc Surgery
This randomized controlled study aims to investigate the effects of ney music listening, a traditional Turkish wind instrument, on pain, anxiety, sleep quality, and vital signs in patients undergoing lumbar disc herniation…
- Conditions
- Lumbar Disc Herniation, Surgery, Nurse's Role
- Trial name
- NCT07171008
- Testing
- Ney music
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Niran Çoban
Lumbar Disc Herniation, Lumbar Disc Surgery
Effectiveness of Virtual Reality-Assisted Physical Therapy in the Acute Phase After Lumbar Disc Surgery
The goal of this clinical trial is to evaluate the effectiveness of virtual reality-assisted physical therapy in the acute postoperative period after lumbar disc surgery.
- Trial name
- NCT07204197
- Testing
- Virtual Reality-Assisted Physical Therapy, Conventional Physical Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hacettepe University