Clinical trials: Lower Urinary Tract Symptoms (LUTS), active
HoLEP, Trifecta Achievement
Predictors of Trifecta Achievement After HoLEP
Holmium laser enucleation of the prostate (HoLEP) is a surgical treatment option for men experiencing bothersome lower urinary tract symptoms due to an enlarged prostate.
- Conditions
- HoLEP, Trifecta Achievement, Urinary Incontinence Following Surgical Procedure, Clavien Dindo Surgical Complication Scale
- Trial name
- ReMIUS-BPO (NCT07429994)
- Testing
- Transurethral Holmium Laser Enuclation of the Prostate
- Where
- Turkey (Türkiye)
- Volunteers
- 604 people
- Sponsor
- Ondokuz Mayıs University
Benign Prostatic Hyperplasia, Bladder Outlet Obstruction
Thulium Laser Enucleation With Bladder Neck Incision for Small-Volume Benign Prostatic Hyperplasia
This study will evaluate the safety and effectiveness of different surgical treatments for men with small-volume benign prostatic hyperplasia (BPH).
- Conditions
- Benign Prostatic Hyperplasia, Bladder Outlet Obstruction, Lower Urinary Tract Symptoms (LUTS)
- Trial name
- ThuLEP-BNI (NCT07569874)
- Testing
- Thulium Laser Enucleation of the Prostate Combined With Bladder Neck Incision, Thulium Laser Enucleation of the Prostate, Transurethral Resection of the Prostate
- Where
- China
- Volunteers
- 932 people
- Sponsor
- Chinese PLA General Hospital
BPH With Symptomatic Lower Urinary Tract Symptoms
ProVee Urethral Expander System IDE Study (ProVIDE)
A study to evaluate the safety, performance, and effectiveness of the ProVee Urethral Expander System (Investigational Device) when used in subjects with symptomatic urinary obstruction related to benign prostatic hyperplasia…
- Trial name
- ProVIDE (NCT05186740)
- Testing
- ProVee Urethral Expander System, Urethral Access Sheath
- Where
- 16 sites in United States, Canada and 1 more
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- ProVerum Medical
Urinary Incontinence (UI), Lower Urinary Tract Symptoms (LUTS)
Reducing Disparities in Urinary Control Symptoms for Minority Women
The study is designed to address the disparity in available conservative/behavioral treatments for UI/LUTS. The program was developed by experts from urogynecology, psychology, and physical therapy then modified based on focus…
- Conditions
- Urinary Incontinence (UI), Lower Urinary Tract Symptoms (LUTS), Pelvic Floor Disorder
- Trial name
- SUPPORT (NCT06798311)
- Testing
- SUPPORT workbook
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Chicago
Benign Prostate Hypertrophy(BPH), LUTS(Lower Urinary Tract Symptoms)
MISTER Study: Minimally Invasive Steam Therapy - Russian Effectiveness Registry
Rezūm is a minimally invasive procedure that uses water vapor (steam) to treat urinary symptoms caused by an enlarged prostate (benign prostatic hyperplasia, BPH).
- Trial name
- MISTER (NCT07723378)
- Testing
- Rezūm
- Where
- Russia
- Volunteers
- 1,400 people
- Sponsor
- Sechenov University
Lower Urinary Tract Symptom, Voiding Dysfunction
Association Between Qmax/eGFR Ratio and LUTS Severity in Men Over 40
This study will look at how well a measure called the Qmax/eGFR ratio is related to the severity of urination problems in men over the age of 40.
- Conditions
- Lower Urinary Tract Symptom, Voiding Dysfunction, Male Urological Health, Renal Function
- Trial name
- NCT07055425
- Volunteers
- 100 people
- Sponsor
- Marmara University
Benign Prostatic Hyperplasia
Enhanced Clinical Decisions for Management of Benign Prostatic Hyperplasia Using Patient-Reported Outcomes
The goal of this project is to use newly developed patient-reported outcomes to improve the clinical care of patients with benign prostatic hyperplasia.
- Trial name
- NCT05898932
- Testing
- Medical Management, Surgical Management
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Urinary Bladder, Overactive, Prostatic Hyperplasia, Benign
Comparison of Concurrent Endoscopic Prostate Surgery With Botox-A Injection and Postoperative Medical Therapy in BPH Patients With Overactive Bladder Symptoms
Intravesical OnabotulinumtoxinA (BoNT-A) injection performed concurrently with endoscopic prostate surgery provides superior clinical improvement at the 12th postoperative week compared to standard medical therapy in patients…
- Conditions
- Urinary Bladder, Overactive, Prostatic Hyperplasia, Benign, Bladder Outlet Obstruction, Botulinium Toxin-A
- Trial name
- BOPROST (NCT07554989)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Multiple Sclerosis (MS), Neurogenic Bladder Disorder
Essential Oils for Urinary Symptoms in Multiple Sclerosis Patients
The goal of this clinical trial is to learn if essential oil aromatherapy works to improve urinary symptoms in adults with multiple sclerosis. It will also learn about the safety of essential oil use in this population.
- Conditions
- Multiple Sclerosis (MS), Neurogenic Bladder Disorder, Urinary Incontinence (UI), Urinary Urgency
- Trial name
- AROMA-MS (NCT07599189)
- Testing
- Essential Oil Blend (Lavender, Rosemary), Neutral Carrier Oil (Apricot Kernel Oil)
- Where
- 2 sites in Algeria
- Volunteers
- 60 people
- Sponsor
- University of Oran 1
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Silodosin vs Tamsulosin for LUTS Due to BPH: A Randomized Crossover Trial
The goal of this randomized crossover clinical trial is to compare the efficacy and safety of Silodosin versus Tamsulosin in patients with moderate to severe lower urinary tract symptoms due to Benign Prostatic Hyperplasia.
- Trial name
- NCT07467343
- Testing
- Silodosin, Tamsulosin
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Benign Prostatic Hyperplasia
Pelvic Floor Muscle Exercise for Lower Urinary Tract Symptoms After Surgery for Benign Prostatic Hyperplasia.
This study aims to evaluate the effectiveness of pelvic floor muscle exercise (PFME) on improving lower urinary tract symptoms (LUTS), postvoid residual volume (PVR), and quality of life in patients undergoing surgery for benign…
- Trial name
- BPH LUTS PFME (NCT07293442)
- Testing
- pelvic floor muscle exercises
- Where
- 2 sites in Taiwan
- Volunteers
- 46 people
- Sponsor
- Taipei Medical University WanFang Hospital
Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
Anterior Bridge-Preserving Versus Conventional Early Apical Release in Bipolar Enucleation of the Prostate
Bipolar enucleation of the prostate is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence (SUI), Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
- Trial name
- ABPS-EAR-BIPO (NCT07893548)
- Testing
- Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
- Volunteers
- 230 people
- Sponsor
- Benha University
Benign Prostatic Hyperplasia (BPH)
REZŪM vs. Dual Drug Therapy for Symptomatic Benign Prostatic Hyperplasia in Sexually Active Men
The study objective is to compare water vapor thermotherapy with the REZŪM™ System to dual drug therapy for the treatment of symptomatic benign prostatic hyperplasia refractory to alpha-blocker monotherapy in sexually active men.
- Trial name
- VAPEUR (NCT04838769)
- Testing
- REZŪM, alpha blocker and 5-alpha reductase inhibitor
- Where
- 21 sites in Australia, France
- Volunteers
- 155 people
- Sponsor
- Boston Scientific Corporation
Benign Prostatic Hyperplasia, Localized Prostate Cancer
PRCT001 Aquablation theraPy Outcomes in pRostate Cancer patienTs
The goal of this clinical trial is to assess the performance and safety of the AQUABEAM Robotic System for the resection and removal of prostate tissue in patients experiencing lower urinary tract symptoms (LUTS) and are…
- Trial name
- NCT06051942
- Testing
- Robotic Waterjet Treatment
- Where
- 6 sites in United States, Hong Kong and 2 more
- Volunteers
- 125 people
- Sponsor
- PROCEPT BioRobotics
BPH (Benign Prostatic Hyperplasia)
Tadalafil 5 mg on Storage Lower Urinary Tract Symptoms After Anatomical Endoscopic Enucleation of the Prostate
The aim of this study is to evaluate the impact of daily tadalafil 5 mg on storage lower urinary tract symptoms (LUTS) during the early postoperative period following Anatomical endoscopic enucleation of prostate in a randomized…
- Trial name
- NCT07466030
- Testing
- Tadalafil 5mg (Male), Omiga 3
- Volunteers
- 40 people
- Sponsor
- Assiut University
Lower Urinary Tract Symptoms (LUTS)
Effects of Macanity on Urinary Health in Males With Lower Urinary Tract Symptoms
The goal of this study is to evaluate the effects of Macanity on urinary health in males experiencing LUTS. Males aged over 40 years of age who experience LUTS will be recruited and assigned to a study treatment which they will…
- Trial name
- NCT07816172
- Testing
- Maca Root
- Where
- Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Benign Prostatic Hypertrophy (BPH), Lower Urinary Track Symptoms
Intradetrusor Onabotulinumtoxin A (Botox) at the Time of Transurethral Resection of the Prostate or Transurethral Waterjet Ablation of the Prostate for Mixed Lower Urinary Tract Symptoms
Patients with longstanding obstructive lower urinary tract symptoms (LUTS) due to benign prostatic hypertrophy (BPH) can also develop symptoms of overactive bladder syndrome (OAB).
- Trial name
- NCT07377929
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Benaroya Research Institute
Lower Urinary Tract Symptoms, Prostate Obstruction
Intermittent vs Daily Tamsulosin for LUTS/BPH
Background: Lower urinary tract symptoms (LUTS) are common in aging men, most often due to benign prostatic hyperplasia (BPH), and significantly impair quality of life.
- Trial name
- ARAB (NCT07308002)
- Testing
- Daily Tamsulosin, Intermittent Tamsulosin
- Where
- Egypt
- Volunteers
- 288 people
- Sponsor
- Mansoura University
BPH (Benign Prostatic Hyperplasia), LUTS(Lower Urinary Tract Symptoms)
Transurethral Thermodilatation vs. Prostatic Urethral Lift for Moderate-to-Severe BPH
This clinical trial aims to determine whether Prolieve® (microwave with balloon dilation) is as effective as UroLift® (prostate implants) for treating moderate-to-severe lower urinary tract symptoms in men aged 50-80 with…
- Trial name
- THRIVE (NCT07759752)
- Testing
- Prolieve Transurethral Thermodilatation System, UroLift Prostatic Urethral Lift System
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
Benign Prostatic Hyperplasia (BPH), Obstructive Lower Urinary Tract Symptoms (LUTS)
Prospective Post Market Clinical Trial for the Zenflow Spring System - A Minimally Invasive Treatment for LUTS Associated With BPH.
This is a prospective, randomized, open-label, parallel-group post-market clinical trial (PMCT). The overall objective of this PMCT is to compare the effectiveness, durability, and patient-centered outcomes of the Zenflow Spring…
- Conditions
- Benign Prostatic Hyperplasia (BPH), Obstructive Lower Urinary Tract Symptoms (LUTS), Enlarged Prostate
- Trial name
- NCT07797348
- Testing
- Zenflow Arm: Zenflow Spring System implant procedure, Medical Therapy Tamsulosin
- Volunteers
- 110 people
- Sponsor
- Zenflow, Inc.