Clinical trials: Lower Extremity Lymphoedema
Lymphedema
Assessment of Unilateral Lymphoedema of the Leg
To demonstrate that ImpediMed L-Dex U400 can be used to assess unilateral Lymphoedema of the leg using the same principles for arms.
- Trial name
- NCT00757406
- Where
- Australia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ImpediMed Limited
Venous Stasis Ulcer, Quality of Patient Care
Venous Leg Ulcer and Lymphedema Registry
This is an observational, longitudinal real world registry of venous leg ulcers created from electronic health record data obtained in the course of clinical care.
- Trial name
- VLULR (NCT02813187)
- Testing
- cellular and tissue based therapy, debridement, advanced wound therapy
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- U.S. Wound Registry
Lymphedema
The Effect of Resistance Exercise in Patients With Lower Limb Lymphedema (the LymphEx Study)
The aim of the study is to investigate the short-term (within 2 weeks) effects of resistance exercise with and without compression garments on lower limb lymphedema(LLL).
- Trial name
- LymphEx (NCT07558317)
- Testing
- Resistance exercise
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Carsten Bogh Juhl
Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy
Extracorporeal Shock Wave Therapy in Lower Extremity Lymphedema
Lower extremity lymphedema is a chronic and progressive condition associated with significant functional impairment and reduced quality of life.
- Conditions
- Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy, Edema Leg, Sham-controlled
- Trial name
- NCT07626645
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Lower Extremity Lymphedema
Evaluate Advanced Pneumatic Compression Device With Revised Compression Programming for Lymphedema Treatment
The goal of this pilot study is to learn if a revised method of compression improves lymphatic function compared to the current method of compression.
- Trial name
- NCT07613931
- Testing
- Advanced pneumatic compression device (APCD), Advanced pneumatic compression device (APCD) with revised compression programming, Indocyanine Green (IC-Green)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Tactile Medical
Lymphedema of Leg, Lymphedema, Secondary
Imaging Sodium and Lymphatics in Lymphedema
Recent evidence supports lymphatic regulation of tissue sodium handling, however fundamental gaps persist in knowledge regarding the role of lymphatics in human diseases of sodium dysregulation.
- Conditions
- Lymphedema of Leg, Lymphedema, Secondary, Lymphedema Related Fibrosis
- Trial name
- NCT05242900
- Testing
- Complete decongestive therapy, Standard imaging protocol
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Virginia
Lymphedema
Effect of Intermittent Pneumatic Compression on Ulcer Healing in Subjects With Secondary Lymphedema
This is a randomized, controlled, parallel group, open label, clinical trial to evaluate the effectiveness of intermittent, gradient, pneumatic compression (IPC)on the healing of venous ulcers in subjects diagnosed with chronic…
- Trial name
- NCT01079299
- Testing
- Intermittent, gradient, pneumatic compression device
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Calvary Hospital, Bronx, NY
Lower Limb Lymphedema, Unilateral Leg Edema
Effects of Hydrotherapy on Unilateral Lower Extremity Lymphedema
Lymphedema is a chronic condition that negatively affects patients' quality of life and lower extremity functions, causing swelling and a feeling of heaviness in the extremity, as well as posing an economic burden.
- Trial name
- NCT06839885
- Testing
- Interventional group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Lymphedema, Lower Limb
Can the Osteopathic Pedal Pump Reduce Lymphedema in the Lower Extremities in the Elderly? A Mentorship Project.
Chronic lymphedema is defined as swelling or edema (excess fluid in the interstitial space) that does not fully resolve overnight by elevating the limb or body part to the level of the heart.
- Trial name
- NCT05119517
- Testing
- Osteopathic manipulative medicine pedal pump
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rowan University
Lower Extremity Lymphedema
Platelet Rich Plasma, Complex Decongestive Physiotherapy and Low Level Laser in Treatment of Lower Extremity Lymphoedema
At the end of the study, comparative information about the effects of PRP, complex decongestive physiotherapy and low level laser on edema volume, range of motion, muscle strength, functional capacity and quality of life will be…
- Trial name
- NCT03080207
- Testing
- PRP method, Low Level Laser, Complex Decongestive Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University
Lower Limb Lymphedema, Urogenital Cancer
Lymphoedema and Nocturia/ Nocturnal Polyuria After Pelvic Lymph Node Dissection for Urogenital Cancer
After the treatment of urogenital cancer, a person may develop lymphoedema of the leg(s) and/ or midline region. Lymphoedema is the result of a dysfunction in the lymphatic system and is characterized by excessive retention of…
- Trial name
- UroLymph (NCT05266157)
- Testing
- Manual lymph drainage, Usual care
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lymphedema
Compression Stockings for Lymphedema Prevention in Gynecologic Cancer Patients
The goal of this clinical trial was to evaluate whether compression stockings (23-32 mmHg) reduce the incidence of postoperative lymphedema and accompanying symptoms, as well as to assess the comfort of using compression in women…
- Trial name
- csplwgm (NCT06873984)
- Testing
- compression products
- Where
- 2 sites in Poland
- Volunteers
- 60 people
- Sponsor
- Joanna Kurpiewska-Pieniążek
Lymphedema
Comparative Trial to Monitor Interface Pressure in Relation to Volume Change in Leg Lymphoedema
Although there is no doubt about the need for compression therapy in lymphoedema, it is not investigated in much detail how much pressure is needed to get optimum volume reduction.
- Trial name
- NCT01828606
- Testing
- coban 2 system, coban lite system
- Where
- 3 sites in Denmark, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Nij Smellinghe Hosptial
Lymphoedema, Breast Cancer
Spa Therapy for Upper or Lower Limb Lymphoedema
THERMOEDEME is a comparative, controlled, randomized, multicenter and simple blinded (investigator) trial. The aim of this study is to evaluate effects of spa therapy in phlebology with a therapeutic education program in daily…
- Conditions
- Lymphoedema, Breast Cancer, Malignant Disease, Gynaecological Cancer
- Trial name
- THERMOEDEME (NCT03580109)
- Testing
- Immediate spa treatment, Late spa treatment
- Where
- 13 sites in France
- Volunteers
- 160 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Lower Extremity Lymphedema, Endometrial Cancer
Lymphedema in Endometrial Cancer
Objectives: (1) To determine the incidence of lower-extremity lymphedema after staging surgery for endometrial cancer; (2) to describe lymphedema-related morbidity after staging surgery for endometrial cancer and (3) to evaluate…
- Trial name
- NCT01914276
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Duke University
Cellulitis, Cellulitis of Arm
Handheld Infrared Thermometer to Evaluate Cellulitis
It can be difficult to differentiate cellulitis from non-infectious mimics, like venous stasis. One way of determining the difference is feeling skin surface temperature.
- Conditions
- Cellulitis, Cellulitis of Arm, Cellulitis of Leg
- Trial name
- HI-TEC (NCT03846635)
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Lymphedema
A 3D Tablet Sensor Approach to the Measurement of a Lymphedema
Up to now, the diagnosis of lymphedema remains hard and delayed. It suffers from many limitations such as lack of coordination and formation of the health-care network.
- Trial name
- LO3D (NCT04821440)
- Testing
- Water displacement volumetry, Three dimension volumetry
- Where
- 2 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Brest
Lymphedema, Lower Limb
The Effect of Dynamic Neuromuscular Stabilization Exercises in Patients With Lower Extremity Lymphedema
After lower extremity lymphedema, individuals physical activity levels and functionality remain very low. This decrease can cause balance problems over time.
- Trial name
- NCT06545383
- Testing
- Dynamic Neuromuscular Stabilization Exercises, Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University - Cerrahpasa
Limb Volume, Measuring Edema
Measuring Volume Using a 3D Scanner and iPad to Grade the Swelling of Legs
We used a new and easy-to-measure iPad 3D scanner to measure swelling in lower limbs because current technology is not easily available or affordable.
- Trial name
- NCT06944041
- Testing
- STO3 sensor (Structure Inc., Boulder, CO)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The RANE Center for Venous and Lymphatic Diseases at St. Dominic's Hospital
Chronic Edema, Lymphedema
Boosted Compression for Lower Limb Chronic Edema
Patients: Patients targeted in this proposal comprise individuals afflicted by chronic edema/lymphedema of the lower limbs. Intervention: The intervention entails the incorporation of boosted compression alongside standard care…
- Trial name
- BECOME (NCT07708662)
- Testing
- Conservative edema treatment (complex decongestive therapy), Conservative edema treatment with boosted compression therapy
- Where
- 4 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- Universiteit Antwerpen