Clinical trials: Lower Extremity Injury
Leg Injuries
Neuromuscular Training to Reduce Sports Injuries Among Children and Adolescents
Sports-related injuries are a serious concern for physically active children and adolescents. Previous research, including ours at Chicago public high schools, shows our neuromuscular training program, the Knee Injury Prevention…
- Trial name
- KIPP (NCT01406054)
- Testing
- neuromuscular exercises
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Ankle Fractures
Ziptight or Tricortical Screw Fixation of Acute Tibiofibular Syndesmotic Injury
Treatment of syndesmotic injury with Weber C fracture. A randomized study comparing ZipTight suture endobutton and one tricortical 3,5 mm syndesmotic screw.
- Trial name
- S16 (NCT02930486)
- Testing
- ZipTight suture endobutton, Tricortical 3.5 mm syndesmotic screw
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Vestre Viken Hospital Trust
Anterior Cruciate Ligament Injury
Effect of Dual Tasks on Gait Symmetry After Anterior Cruciate Ligament Reconstruction
Individuals who received anterior cruciate ligament (ACL) reconstruction demonstrated lower extremity movement asymmetries. The purpose of this study was to determine if psychological impairment was a contributor to lower…
- Trial name
- NCT04461145
- Testing
- command
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Peking University Third Hospital
Major Trauma
Enhanced Rehabilitation After Major Trauma (PROPERLY)
The goal of this study is to assess the feasibility of recruitment, and barriers to delivery of an enhanced rehabilitation service, in patients surviving major trauma.
- Trial name
- PROPERLY (NCT05652790)
- Testing
- Enhanced Rehabilitation Programme, Standard Care
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Manchester University NHS Foundation Trust
Pelvic Fracture, Urethra Tear
Primary Urethral Realignment Versus Suprapubic Cystostomy After Pelvic Fracture Urethral Injury
Pelvic fracture urethral injuries (PFUI) occur in up to 10% of pelvic fractures. It remains controversial whether initial urethral realignment after PFUI decreases rates of urethral obstruction and the need for subsequent…
- Conditions
- Pelvic Fracture, Urethra Tear, Urethra Injury Male, Trauma
- Trial name
- NCT03195179
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Joint Instability, Ankle Sprains
Functional Electrical Stimulation in Chronic Ankle Instability
Individuals with chronic ankle instability (CAI) display neuromuscular deficits such as altered control of posture and gait when compared with healthy controls.
- Conditions
- Joint Instability, Ankle Sprains, Sport Injury
- Trial name
- ESCAIP (NCT04314960)
- Testing
- Functional electrical stimulation device (NESS L300Plus, Bioness, Valencia, CA)
- Where
- Israel
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Shmuel Springer
Hip Fracture, Perioperative Myocardial Injury
Nerve Block and Perioperative Myocardial Injury in Elderly Hip Fracture
This single-center, retrospective cohort study evaluates whether a single preoperative peripheral nerve block can reduce the risk of perioperative myocardial injury in elderly patients undergoing delayed hip fracture surgery…
- Conditions
- Hip Fracture, Perioperative Myocardial Injury, Myocardial Injury After Noncardiac Surgery
- Trial name
- PNB-CARD (NCT07751146)
- Testing
- PNB, Non-PNB
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
ACL Injury
Continuous Vs Single Shot Block After ACL
The investigators will be randomizing patients to either receive an adductor canal block in the operating room postoperatively as single shot of 20-30cc bupivacaine or to have a catheter inserted into the adductor canal which…
- Trial name
- NCT04101682
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Spinal Cord Injury
Lokomat Versus Strength Training in Chronic Incomplete Spinal Cord Injury
The purpose of this pilot study is to investigate whether gait specific robotic supported bodyweight supported treadmill training and lower extremity strength training have similar beneficial effects on walking function and other…
- Trial name
- NCT01087918
- Testing
- RAGT, Strength Training
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- University of Zurich
ACL Injury, Knee Injuries
Subjective Outcomes After ACL Reconstruction With BQT Autograft
The purpose of the study is to compare short-term patient reported outcome measures (PROM) of Bone-Quadriceps-Tendon (BQT) autograft with Semitendinosus-Gracilis (STG) and Bone-Patellar-Tendon-Bone (BPTB) autografts following…
- Trial name
- NCT04901559
- Testing
- Graft type at ACLR
- Volunteers
- 30,000 people
- Sponsor
- Region Zealand
ACL Injury
Immediate Versus Optional Delayed Surgical Repair for Treatment of Acute ACL Injuries
Currently, most patients with an anterior cruciate ligament injury undergo surgery. There is a general belief that surgical reconstruction is necessary to safely return to sports and to prevent early knee osteoarthritis or…
- Trial name
- IODA (NCT05747079)
- Testing
- Rehabilitation, Optional delayed anterior cruciate ligament reconstruction, Immediate anterior cruciate ligament reconstruction
- Where
- Belgium
- Volunteers
- 280 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Postoperative Pain, Lower Limb Injury
Block Duration After Spinal Block and iv Dexamethasone.
It has been largely demonstrated that iv dexamethasone prolongs the duration of analgesia after peripheral nerve block. However, data are missing regarding the duration of analgesia after spinal block.
- Trial name
- NCT03527576
- Testing
- Dexamethasone, NaCl 0.0308 MEQ/ML Injectable Solution
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Eric Albrecht
Anterior Cruciate Ligament Injury
Effect of Adding Vastus Medialis Nerve Block to Adductor Canal Block After Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) reconstruction is frequently associated with moderate to severe postoperative pain, which can delay mobilization and rehabilitation.
- Trial name
- VAMA (NCT07683078)
- Testing
- Adductor Canal Block (ACB) Only, Vastus Medialis Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Lower Limb Ischaemia, Aneurysm
Bacterial Growth in Vascular Surgery Wounds
The amount and species of bacteria have been shown to have an effect in wound infections in several fields of surgery (such as gastrointestinal and orthopaedic surgery and the surgery of facial area).
- Trial name
- NCT01505738
- Testing
- bacterial samples
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- North Karelia Central Hospital
Lower Extremity Diabetic Leg Wounds, Lower Extremity Venous Leg Wounds
Clinical Evaluation of the SNaP Wound Care System in Promoting Healing in Chronic Wounds
The purpose of this study is to evaluate a novel topical negative pressure (TNP) wound therapy device called the SNaP® (Smart Negative Pressure) Wound Care System for the treatment of lower extremity diabetic, venous and mixed…
- Conditions
- Lower Extremity Diabetic Leg Wounds, Lower Extremity Venous Leg Wounds, Lower Extremity Mixed Aetiology Leg Wounds
- Trial name
- NCT01417208
- Testing
- SNaP® Wound Care System
- Where
- United Kingdom
- Sponsor
- KCI USA, Inc
Lower Limb Amputation Below Knee (Injury)
Influence of Socket Volume on Prosthesis Performance
The purpose of this study is to investigate how residual limb fluid volume, gait, prosthesis use, perceived comfort, and satisfaction with the prosthesis are affected by size of the prosthetic socket.
- Trial name
- CAD (NCT02124915)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Washington
Radius; Fracture, Lower or Distal End, Tendon Injury - Upper Limb
Screw Lengths in Radius Volar Plates
Background Fractures of the distal radius are among the most common. Major complications, including irritation and rupture of the extensor tendons, may occur if epiphyseal screws of inappropriate length are used.
- Conditions
- Radius; Fracture, Lower or Distal End, Tendon Injury - Upper Limb, Fracture Fixation, Internal
- Trial name
- PESLDRF (NCT03634865)
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Brest
Prosthesis User, Lower Limb Amputation Below Knee (Injury)
Caesar Foot Take-Home Validation Testing
The rationale for this study is to conduct a take-home clinical trial to evaluate the impact of the bimodal Caesar foot in a real-world environment.
- Trial name
- NCT07075198
- Testing
- Caesar Foot
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Liberating Technologies, Inc.
ACL, Anterior Cruciate Ligament
Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction
The goal of this study is to gather pilot data to help inform a future clinical trial. As such, the investigators will employ a randomized clinical trial design, but data will only be collected on 9 total subjects.
- Conditions
- ACL, Anterior Cruciate Ligament, ACL Injury
- Trial name
- Mi-SPA (NCT06529692)
- Testing
- Split-Belt Training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Michigan
Critical Lower Limb Ischemia, Critical Limb Ischemia
Evaluation of Carbothera in the Treatment of Foot Ulcers
Foot ulceration usually precedes more serious foot complications such as infection, gangrene or amputation. The risk of developing foot ulcers has been estimated to be higher in individuals with kidney disease.
- Conditions
- Critical Lower Limb Ischemia, Critical Limb Ischemia, Foot Ulcer, Skin Ulceration
- Trial name
- NCT02239419
- Testing
- CO2-Enriched Tap Water (Carbothera), Non-CO2-Enriched Tap Water
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba