Clinical trials: Lower Extremity Injuries
Femur Fractures
Types of Fixation of Vancouver B1 Periprosthetic Fractures
The purpose of this study is to compare two different but standard treatments for the fixation of Vancouver B1 periprosthetic. The investigators aim to compare open reduction internal fixation using a locked plating system versus…
- Trial name
- NCT01354535
- Testing
- Isolated Locked Compression Plate, Cable Plating and Strut Allograft with Cerclage Wiring
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- Unity Health Toronto
Pelvic Fracture
A Prospective Study of Early Mechanical Stabilization and Bleeding in Disruption of the Pelvic Ring
The objective of this study is to evaluate the effect of earlier placement of Circumferential Pelvic Compression (CPC) on resuscitative measures required for life-threatening pelvic ring injuries and to guide the development of…
- Trial name
- EMS-BIND (NCT03977168)
- Testing
- Application of circumferential pelvic compression (CPC) device
- Where
- 11 sites in United States
- Volunteers
- 600 people
- Sponsor
- Major Extremity Trauma Research Consortium
Anterior Cruciate Ligament Injuries, Lower Extremity Problem
Knowledge Translation Intervention for ACL Injury Prevention Program in Youth Soccer
Anterior cruciate ligament (ACL) injuries of the knee are common in youth soccer players, and show an even higher prevalence in female soccer players.
- Trial name
- NCT05442879
- Testing
- Knowledge Translation Intervention, Educational handout
- Where
- United States
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Tibia Fracture, Femur Fracture
Bimodal Analgesia as Form of Pain Control Post Long Bone Fracture
The purpose of this prospective randomized study is to evaluate the risks and benefits of using bimodal analgesia, (i.e. Narcotics and NSAIDS) vs Narcotics alone post long bone fracture.
- Conditions
- Tibia Fracture, Femur Fracture, Humerus Fracture
- Trial name
- NCT00240396
- Testing
- Narcotics alone, Narcotics and NSAIDS
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Pain, Postoperative
Preoperative Pain Catastrophizing and Its Association With Postoperative Pain After Lower Limb Trauma Surgery
The Pain Catastrophizing Scale (PCS) is a psychometric tool to identify PC. A positive correlation between PCS scores and various pain outcomes has been reported in acute and chronic pain settings.
- Trial name
- NCT03758560
- Testing
- Pre-operative Nepali version of pain catastrophizing scale (PCS) questionnaire
- Where
- Nepal
- Volunteers
- 135 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Venous Leg Ulcer
Evaluation of Pain Associated With the Removal of Wound Dressing During Care of Venous Leg Ulcer. Comparison of the Efficacy and Safety of Two Dressings Urgotul and TulleGras
Evaluation of the non-inferiority of TulleGras M.S.® versus Urgotul® in pain associated with removal of wound dressing during care of venous leg ulcer
- Trial name
- NCT02104180
- Testing
- Urgotul, TulleGras M.S.
- Where
- 27 sites in France
- Volunteers
- 62 people
- Sponsor
- Mylan Inc.
Educational Problems, Simulation of Physical Illness
Learning Management of Open Fractures on Virtual Patient
A novel virtual world programme with over 240 multiple choice questions was developed to assess the competencies in managing an open fracture of the lower limb according to the British Orthopaedic Association Standards for Trauma…
- Conditions
- Educational Problems, Simulation of Physical Illness, Fractures, Bone, Emergencies
- Trial name
- NCT04605380
- Testing
- Virtual reality online world
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Ankle Fracture
Telerehabilitation in Patients With Ankle Fracture
The objective of this clinical trial is to determine the effectiveness of a telerehabilitation program in the recovery of functionality and quality of life in patients recovering from ankle fracture.
- Trial name
- NCT06811090
- Testing
- Tele-rehabilitation, Hospital rehabilitation
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Instituto Mexicano del Seguro Social
Dementia, Femur Fracture
Care of Older People With Cognitive Impairment or Dementia Hospitalized in Traumatology Units
This is a quasi-experimental design with repeated observations, taken at baseline, post-intervention, and at one and three months post-intervention.
- Conditions
- Dementia, Femur Fracture, Continuity of Patient Care
- Trial name
- CARExDEM (NCT04048980)
- Testing
- CARExDEM
- Where
- Spain
- Volunteers
- 432 people
- Sponsor
- Hospital Clinic of Barcelona
Posterior Malleolus Fractures
Surgical Management of Posterior Malleolar Fractures Using the Direct or Indirect Reduction Techniques
Patients with a posterior malleolar fracture were recruited and assigned to the direct reduction (DR) group or the indirect reduction (IR) group.
- Trial name
- NCT02801474
- Testing
- direct fracture reduction and fixation, indirect fracture reduction and fixation
- Where
- China
- Volunteers
- 148 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Leg Ulcers Venous, Dehiscence, Surgical Wound
Blu Light for Ulcers Reduction
Multi-center study on the effectiveness of treatment with a blue light medical device (EmoLED) in the reduction of ulcer surface in 10 weeks.
- Trial name
- BLUR (NCT04018924)
- Testing
- Illumination with blue light (400-430nm) for 60 seconds with a power density of 120mW/sqcm (EmoLED device)
- Where
- 7 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Emoled
Iliotibial Band Syndrome
Comparative Effects of Clamshells and Frog Pump Exercises
Iliotibial band syndrome is where a tendon called iliotibial band gets irritated or swollen from rubbing against hip or knee when it gets too tensed.
- Trial name
- NCT05973708
- Testing
- Clamshell Exercise, Frog pump exercise
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Anterior Cruciate Ligament Rupture, Tendon Injuries
Shear-Wave Elastography of Regenerated Hamstring Tendons After ACL Reconstruction (SWE-ACL)
Anterior cruciate ligament (ACL) reconstruction using autologous hamstring tendon grafts is a commonly performed procedure. Although the semitendinosus and gracilis tendons demonstrate regeneration at the donor site, the…
- Conditions
- Anterior Cruciate Ligament Rupture, Tendon Injuries, Muscle Weakness
- Trial name
- SWE-ACL (NCT07555782)
- Testing
- Shear-Wave Elastography Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Sprain of Ankle
Use of Platelet Rich Plasma Therapy for Acute Ankle Sprains in the Emergency Department
This research study hopes to determine whether or not platelet rich plasma therapy improves healing time of moderate to severe ankle sprain in comparison to standard of care therapy.
- Trial name
- PRP (NCT01518335)
- Testing
- Platelet rich plasma injection
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Albert Einstein Healthcare Network
Running Biomechanics, Neuromuscular Control
Structured Neuromuscular Exercise Program
This randomized controlled trial aims to investigate the effects of an 8-week structured neuromuscular exercise program on running performance and lower extremity biomechanics in recreational runners.
- Conditions
- Running Biomechanics, Neuromuscular Control, Running-Related Injury Prevention, Recreational Runners
- Trial name
- nmep-run (NCT07596420)
- Testing
- Structured Neuromuscular Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Elif Tunç
Ankle Sprain
Ankle Sprain Rehabilitation With the Wii Balance Board
Physical activity and in particular sport is beneficial to health. Nevertheless, some of these activities may create a risk of injury. Ankle sprain is the most common sport related injury.
- Trial name
- NCT01449760
- Testing
- Physical Therapy, Wii Balance Board
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- University Hospital, Geneva
Anterior Cruciate Ligament Injuries, Sports Injury
Neuromusculoskeletal Alterations After ACL Injury
This study investigated how anterior cruciate ligament (ACL) injuries affect not only the knee joint but also brain activity, reaction speed, and psychological readiness to return to sports.
- Conditions
- Anterior Cruciate Ligament Injuries, Sports Injury, Neurocognitive Function
- Trial name
- NEURO-ACL (NCT07163468)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
Femoral Neck Fracture
Full Versus Partial Repairing of Soft Tissue Surrounding the Hip in Arthroplasty for Femoral Neck Fractures
A prospective cohort study to compare full repairing and partial repairing of soft tissue surrounding the hip joint in anteriorolateral approaching arthroplasty concerning hip function.
- Trial name
- NCT02897440
- Testing
- Full Repairng of soft tissue surrounding the hip, Partial Repairng of soft tissue surrounding the hip
- Volunteers
- 30 people
- Sponsor
- First Hospitals affiliated to the China PLA General Hospital
Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament Injury Prevention Protocol in Female Football Players With Dynamic Knee Valgus
Introduction: Women's football has experienced exponential growth over the last ten years. Its popularity is associated with an increase in anterior cruciate ligament injuries (ACL).
- Trial name
- NCT06083818
- Testing
- Application of an anterior cruciate ligament injury prevention protocol for female football players with dynamic knee valgus for 12 weeks.
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Amanda Coves García
Hip Fractures
Effect of Leg Strengthening Exercise After Hip Fracture
The purpose of this trial was to examine the effectiveness of a short-term leg strengthening exercise program compared to attention control on improving leg strength, walking speed and endurance, physical performance, and…
- Trial name
- NCT00997776
- Testing
- progressive resistance exercise, TENS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Arcadia University