Running Biomechanicsnmep-runNCT07596420
Structured Neuromuscular Exercise Program
A study testing Structured Neuromuscular Exercise Program in people with Running Biomechanics and Neuromuscular Control, run by Elif Tunç at 1 site in Turkey (Türkiye).
Trial summary
This randomized controlled trial aims to investigate the effects of an 8-week structured neuromuscular exercise program on running performance and lower extremity biomechanics in recreational runners. Read more about this study
- Who is it for?
- Ages 18 to 55 yearsHealthy volunteers can take part
- Conditions the study is for
- Running Biomechanics, Neuromuscular Control, Running-Related Injury Prevention
- What is being tested?
- Structured Neuromuscular Exercise Program
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 24 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- May 2026to Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 55 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Age between 18 and 55 years
- Recreational runners who have been running regularly (at least twice per week for the last 6 months)
- No current musculoskeletal injury limiting running
- Willing to participate in the 8-week neuromuscular exercise program and attend follow-up assessments
- Able to provide informed consent
Who cannot join
- History of lower limb surgery or fracture in the past 6 months
- Neurological, vestibular, or systemic diseases affecting balance or gait
- Current participation in a structured strength or neuromuscular training program
- Pregnancy
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: The Effect of s Structured Neuromuscular Exercise Program on Running Performance and Lower Extremity Biomechanics in Recreational Runners
This randomized controlled trial aims to investigate the effects of an 8-week structured neuromuscular exercise program on running performance and lower extremity biomechanics in recreational runners. The program includes progressive exercises focusing on hip and core strength, balance, plyometric control, and running-specific mobility. Participants will be randomly assigned to an intervention or control group. The intervention group will perform the neuromuscular training twice a week for eight weeks, while the control group will not receive any structured exercise. Pre- and post-intervention assessments will include biomechanical analysis and functional performance tests. The study aims to provide evidence for the preventive and performance-enhancing benefits of neuromuscular training in runners.
Read the detailed description
Running is a repetitive and high-impact activity that places significant mechanical stress on the lower extremities. Improper movement patterns, muscle imbalances, and reduced neuromuscular control have been identified as key contributors to running-related injuries. Previous studies have demonstrated that neuromuscular training can enhance movement efficiency, improve joint stability, and reduce injury risk in athletic populations. However, there is limited evidence on the structured and progressive application of neuromuscular exercise programs specifically designed for recreational runners.
The present randomized controlled trial aims to evaluate the effects of an 8-week structured neuromuscular exercise program on running performance and lower extremity biomechanics in recreational runners. The intervention includes progressive exercises focusing on hip and core strength, dynamic balance, plyometric control, and running-specific mobility. Participants will be randomly assigned to either an intervention or control group. The intervention group will perform the neuromuscular training twice weekly under supervision, while the control group will maintain their usual physical activity routine. Biomechanical assessments and functional performance tests will be conducted before and after the intervention period. This study seeks to provide scientific evidence supporting the preventive and performance-enhancing benefits of neuromuscular training in runners, contributing to injury prevention and performance optimization strategies.
- Conditions
- Running Biomechanics, Neuromuscular Control, Running-Related Injury Prevention, Recreational Runners
- Being tested
- Structured Neuromuscular Exercise Program
- Keywords
- Neuromuscular Exercise, Performance, Balance, Core Strength, Hip Stability, Lower Limb Biomechanics, Injury Prevention, Running Training
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Structured Neuromuscular Exercise ProgramBehavioural
An 8-week structured neuromuscular exercise program including progressive exercises targeting hip and core strength, dynamic balance, plyometric control, and running-specific mobility. The program is performed twice per week under supervision. It is designed to improve running performance, neuromuscular control, and lower limb biomechanics in recreational runners.
| Study group | Role | What they receive |
|---|---|---|
| NEUROMUSCULAR EXERCISE GROUP | Experimental | Participants in this group will not receive any structured exercise program during the 8-week intervention period. They will maintain their usual physical activity and running habits. Assessments will be performed at the same pre- and post-intervention time points as the intervention group. Receives: Behavioral: Structured Neuromuscular Exercise Program |
| CONTROL GROUP | No intervention | Participants in this group will not receive any structured exercise program during the 8-week intervention period. They will maintain their usual physical activity and running habits. Assessments will be performed at the same pre- and post-intervention time points as the intervention group. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Running performance
Change in running performance will be assessed using a standardized time-trial test to evaluate the effectiveness of the neuromuscular exercise program in improving endurance and speed in recreational runners.
Measured: Baseline and after 8 weeks of intervention
Secondary outcomes (2)
Dynamic balance
Balance performance will be evaluated using the Y-Balance Test to determine improvements in postural control after the neuromuscular training intervention.
Measured: Baseline and after 8 weeks of intervention
Lower limb strength
hip abductor muscle strength will be measured using handheld dynamometry
Measured: Baseline and after 8 weeks of intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 May 2026
- Study startMay 2026 (estimated)
- Primary completionSep 2026 (estimated)
- Study completionSep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Running BiomechanicsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned to either a neuromuscular exercise intervention group or a control group. Both groups will be assessed before and after the 8-week intervention period.
- Masking
- None (open label)
- Enrolment
- 24 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Elif Tunç
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Elif Tunç, Istinye University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07596420
- Sponsor's protocol ID
- ISTINYE-NMEP-2025
- Acronym
- nmep-run
- Status last verified
- Jan 2026
- First submitted
- 1 Jan 2026
- Last updated
- 19 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data (IPD) will not be shared because the dataset includes identifiable physiological and biomechanical data collected from human participants. Data sharing is restricted by ethical approval and participant consent regulations. Only aggregated results will be reported in publications.
Publications
Hammes D, Aus der Funten K, Kaiser S, Frisen E, Bizzini M, Meyer T. Injury prevention in male veteran football players - a randomised controlled trial using "FIFA 11+". J Sports Sci. 2015;33(9):873-81. doi: 10.1080/02640414.2014.975736. Epub 2014 Nov 5.
PubMed 25370591
Study at a glance
From the registry record, last updated by the sponsor on 19 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of s Structured Neuromuscular Exercise Program on Running Performance and Lower Extremity Biomechanics in Recreational Runners
- ClinicalTrials.gov ID
- NCT07596420
- Acronym / sponsor ID
- nmep-run / ISTINYE-NMEP-2025
- Conditions
- Running Biomechanics, Neuromuscular Control, Running-Related Injury Prevention, Recreational Runners
- Keywords
- Neuromuscular Exercise, Performance, Balance, Core Strength, Hip Stability, Lower Limb Biomechanics, Injury Prevention, Running Training
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 24 participants (estimated)
- Lead sponsor
- Elif TunçUniversity, hospital or other
- Study start
- May 2026 (estimated)
- Primary completion
- Sep 2026 (estimated)
- Study completion
- Sep 2026 (estimated)
- First posted
- 19 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial aims to investigate the effects of an 8-week structured neuromuscular exercise program on running performance and lower extremity biomechanics in recreational runners. The program includes progressive exercises focusing on hip and core strength, balance, plyometric control, and running-specific mobility. Participants will be randomly assigned to an intervention or control group. The intervention group will perform the neuromuscular training twice a week for eight weeks, while the control group will not receive any structured exercise. Pre- and post-intervention assessments will include biomechanical analysis and functional performance tests. The study aims to provide evidence for the preventive and performance-enhancing benefits of neuromuscular training in runners.
Detailed description
Running is a repetitive and high-impact activity that places significant mechanical stress on the lower extremities. Improper movement patterns, muscle imbalances, and reduced neuromuscular control have been identified as key contributors to running-related injuries. Previous studies have demonstrated that neuromuscular training can enhance movement efficiency, improve joint stability, and reduce injury risk in athletic populations. However, there is limited evidence on the structured and progressive application of neuromuscular exercise programs specifically designed for recreational runners.
The present randomized controlled trial aims to evaluate the effects of an 8-week structured neuromuscular exercise program on running performance and lower extremity biomechanics in recreational runners. The intervention includes progressive exercises focusing on hip and core strength, dynamic balance, plyometric control, and running-specific mobility. Participants will be randomly assigned to either an intervention or control group. The intervention group will perform the neuromuscular training twice weekly under supervision, while the control group will maintain their usual physical activity routine. Biomechanical assessments and functional performance tests will be conducted before and after the intervention period. This study seeks to provide scientific evidence supporting the preventive and performance-enhancing benefits of neuromuscular training in runners, contributing to injury prevention and performance optimization strategies.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned to either a neuromuscular exercise intervention group or a control group. Both groups will be assessed before and after the 8-week intervention period.
| Arm | Type | Receives |
|---|---|---|
| NEUROMUSCULAR EXERCISE GROUP | Experimental | Behavioral: Structured Neuromuscular Exercise ProgramParticipants in this group will not receive any structured exercise program during the 8-week intervention period. They will maintain their usual physical activity and running habits. Assessments will be performed at the same pre- and post-intervention time points as the intervention group. |
| CONTROL GROUP | No intervention | –Participants in this group will not receive any structured exercise program during the 8-week intervention period. They will maintain their usual physical activity and running habits. Assessments will be performed at the same pre- and post-intervention time points as the intervention group. |
Who may qualify
- Ages
- 18 to 55 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Age between 18 and 55 years
- Recreational runners who have been running regularly (at least twice per week for the last 6 months)
- No current musculoskeletal injury limiting running
- Willing to participate in the 8-week neuromuscular exercise program and attend follow-up assessments
- Able to provide informed consent
Key exclusion criteria (4 listed)
- History of lower limb surgery or fracture in the past 6 months
- Neurological, vestibular, or systemic diseases affecting balance or gait
- Current participation in a structured strength or neuromuscular training program
- Pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Structured Neuromuscular Exercise ProgramAn 8-week structured neuromuscular exercise program including progressive exercises targeting hip and core strength, dynamic balance, plyometric control, and running-specific mobility. The program is performed twice per week under supervision. It is designed to improve running performance, neuromuscular control, and lower limb biomechanics in recreational runners. | Behavioural | NEUROMUSCULAR EXERCISE GROUP |
Primary outcome
Running performance
Time frame: Baseline and after 8 weeks of intervention
Change in running performance will be assessed using a standardized time-trial test to evaluate the effectiveness of the neuromuscular exercise program in improving endurance and speed in recreational runners.
2 secondary outcomes
Dynamic balance
Time frame: Baseline and after 8 weeks of intervention
Lower limb strength
Time frame: Baseline and after 8 weeks of intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 May 2026.
- Background: PubMed 25370591Hammes D, Aus der Funten K, Kaiser S, Frisen E, Bizzini M, Meyer T. Injury prevention in male veteran football players - a randomised controlled trial using "FIFA 11+". J Sports Sci. 2015;33(9):873-81. doi: 10.1080/02640414.2014.975736. Epub 2014 Nov 5.
- Individual participant dataSharing planned: No. Individual participant data (IPD) will not be shared because the dataset includes identifiable physiological and biomechanical data collected from human participants. Data sharing is restricted by ethical approval and participant consent regulations. Only aggregated results will be reported in publications.
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Recruiting
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Healthy
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Structured Neuromuscular Exercise Program in people with Running Biomechanics and Neuromuscular Control, run by Elif Tunç at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 19 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact ELIF TUNC, PhD (090-535-076-3139, fzteliftunc@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Running performance (time frame: Baseline and after 8 weeks of intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07596420, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 May 2026.