Clinical trials: Lower Extremity Blood Flow
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Healthy Adult Male, Healthy Adult Females
Investigating Sex Differences in Mitochondrial Function and Leg Blood Flow During Exercise
This study will compare mitochondrial function and leg blood flow during exercise in healthy endurance-trained females and males aged 19-35.
- Trial name
- MITOP (NCT07866651)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Athletes
The Acute Effects of Static and PNF Stretching Exercise With Blood Flow Restriction in Athletes
The study aims to examine the acute effects of static and proprioceptive neuromuscular facilitation stretching exercises with blood flow restriction on hamstring flexibility, muscle strength, and single leg hop in athletes.
- Trial name
- NCT06656858
- Testing
- Static stretching, PNF stretching, Static stretching with BFR
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Anterior Cruciate Ligament Tear, Knee Injuries
Use of Blood Flow Restriction Therapy Following ACL Tear
Evaluating the use of peri-operative blood flow restriction therapy surrounding anterior cruciate ligament tear
- Conditions
- Anterior Cruciate Ligament Tear, Knee Injuries, Sport Injury
- Trial name
- NCT04374968
- Testing
- Blood flood restriction cuff
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Health Behavior, Muscle Strain, Lower Leg
Effect of Tissue Flossing on Recovery Time After Intense Physical Exercise Causing Delayed Onset Muscle Soreness
The aim of the study is to assess whether soft tissue flossing therapy will alleviate eccentric muscle-destroying influences. Men aged 20-25 will be tested.
- Trial name
- NCT05684315
- Testing
- soft tissue flossing therapy
- Where
- Poland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Deep Vein Thrombosis
Improving Lower Limb Blood Flow in Healthy Adult Volunteers
The THRIVE-1 study will examine novel methods for enhancing blood flow in the lower limb using electrical stimulation. Increases in lower limb blood flow improve venous return and thereby reduce venous stasis.
- Trial name
- THRIVE-1 (NCT01981733)
- Testing
- geko
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Blood Flow Restriction Training
Two Time a Week vs. Five Time a Week Blood Flow Restriction Training Program for the Lower Extremity.
This study will randomize healthy adults who regularly perform resistance training exercises for the lower extremities (2x a week) to one of three groups: a blood flow restriction (BFR) exercise group that trains 2x a week, a BFR…
- Trial name
- NCT05342909
- Testing
- 5x a week BFR training group, 2x a week BFR training group
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- George Fox University
Anterior Cruciate Ligament Tear
Personalized Blood Flow Restriction for Anterior Cruciate Ligament Rehabilitation
This is a cross-sectional study on the use of personalized blood flow restriction during rehabilitation exercises and its effects on biomechanics on people who have had an anterior cruciate ligament reconstruction and healthy…
- Trial name
- NCT04635579
- Testing
- Blood flow restriction
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Washington
Delfi Cuff, Fitcuff
The Influences of Blood Flow Restriction on Leg Press
This study will investigate the use of different blood flow restriction cuffs during leg press exercise on arterial stiffness, muscle morphology, performance, and participant perception.
- Conditions
- Delfi Cuff, Fitcuff, Placebo - Control
- Trial name
- NCT07052227
- Testing
- Delfi blood flow restriction cuff, Fitcuffs, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Salisbury University
Venous Thrombosis
A Comparison of the Effects of Neuromuscular Electrical Stimulation and Intermittent Pneumatic Compression on Blood Flow in the Lower Limb
Deep Vein Thrombosis (DVT) is a life threatening condition and a serious concern among hospitalized patients, with death occurring in approximately 6% of cases.
- Trial name
- NCT01894997
- Testing
- Neuromuscular electrical stimulator, AV Impulse System Model 6000
- Where
- Ireland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Healthy
Evaluation of Three Neuromuscular Electrical Stimulation Foot Pad Programmes on Lower Limb Haemodynamics in Healthy Adults
The goal of this clinical investigation is to evaluate the performance of three neuromuscular electrical stimulation (NMES) foot pad programmes in healthy adults.
- Trial name
- TRI-HEX (NCT07666828)
- Testing
- Medic, P1, PM7
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Joey Porter
Chronic Limb Threatening Ischemia
Multimodal Noninvasive Assessment of Peripheral Circulation in Chronic Limb-threatening Ischemia
Assessment of a novel diagnostic method for screening and diagnosing chronic limb-threatening ischemia (CLTI). Using hyperspectral and thermal imaging, the perfusion and oxygenation in the lower limbs will be studied in healthy…
- Trial name
- NCT05786001
- Where
- Finland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tampere University
Neuromuscular Function, Athletic Performance Enhancement
Effects of Blood Flow Restriction Training on Neuromuscular Function and Performance in Artistic Jump Rope Athletes
The goal of this randomized controlled trial is to investigate whether blood flow restriction training can improve physical function and sports performance in artistic jump rope athletes.
- Trial name
- NCT07750977
- Testing
- Blood Flow Restriction Training, Conventional Artistic Jump Rope Training
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Sport
Bone Loss, Hypotensive
Blood Flow and Bone Density in Healthy Adult Women
This project will test the efficacy of using a non-invasive neuromuscular stimulation on the plantar surface of the feet to prevent and/ or reverse bone loss in a sample of healthy adult women.
- Conditions
- Bone Loss, Hypotensive, Lower Limb Fluid Pooling
- Trial name
- NCT00397462
- Testing
- calf muscle pump stimulation
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Binghamton University
Diabetes, Healthy
Non-invasive Measurement of Microvascular Blood Flow During Mild External Compression of the Leg
SPECIFIC AIMS The limbs of diabetic patients are associated with decreases in capillary density, arterial inflow, and local blood flow of the leg.
- Trial name
- NCT01804478
- Testing
- Mild pneumatic compression
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Lower Limb Injury
Blood Flow Restriction Therapy in Lower Limb Extensor Injuries
The primary objective of the study is to determine the efficacy of blood flow restriction therapy on patients with lower limb extensor injuries by measuring pre and post blood flow restriction therapy strength and muscle mass.
- Trial name
- NCT04149977
- Testing
- Physical Therapy with pressure cuff
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Muscle Strength, Muscle Hypertrophy
Effects of BFR Training on Muscle Strength, Thickness, and Motivation in National Adolescent Male Canoe Athletes
The aim of this study is to evaluate the effects of blood flow restriction (BFR) exercises on lower extremity muscle strength, muscle thickness, and sport-specific motivation in adolescent elite male canoe athletes.
- Conditions
- Muscle Strength, Muscle Hypertrophy, Sport Performance
- Trial name
- BRAVE-CAN (NCT06912867)
- Testing
- Blood Flow Restriction (BFR) Exercise Program
- Where
- Cyprus
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Type 2 Diabetes
Type 2 Diabetes and Exercise Function in Single Leg Exercises
This study plans to learn more about the effects of type 2 diabetes (T2DM) on exercise blood flow and muscle oxygen uptake. This study will evaluate \& compare exercise function during single leg plantar flexion exercise in a…
- Trial name
- NCT01793909
- Testing
- Single Leg Exercise Training
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Ankle Sprain, Ankle Instability
Auto-regulated Blood Flow Restriction in Athletes With Recurrent Ankle Sprain
Ankle injuries, especially lateral ankle sprains, are prevalent in physically active individuals. Blood Flow Restriction Training (BFRT) has emerged as a promising method, employing partial arterial occlusion and full venous…
- Trial name
- NCT06962943
- Testing
- Auto-regulated Blood Flow Restriction Training, Non-regulated Blood Flow Restriction Training, Control group
- Where
- United Arab Emirates
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Cardiovascular Disease
Evaluation of Patients With Heart Disease Not Eligible for Research Protocols
An important mission of the National Institutes of Health (NIH) is to develop and carry out research studies designed to improve understanding of disease processes and treatments.
- Trial name
- NCT00001458
- Where
- United States
- Volunteers
- 7,829 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)