Clinical trials: Lower Extremity
Edema Leg
The Effect of Compression Stockings on Edema and Discomfort During Short Haul Flights
Compression stockings have beneficial effects on the development of venous thromboembolic complications and oedema during long- haul flights.
- Trial name
- NCT03546725
- Testing
- Compression stocking
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Blood Lactic Acid Increased, Hip Fractures
Optimal Blood Sampling Site for Point of Care Lactate Assessment
The study was to compare blood Lactate levels between ear lobe and finger against venous forearm blood sample using the electronic hand held lactate device in hip fracture patients with good cognitive function (AMT >/= 7)
- Trial name
- NCT04291989
- Testing
- Optimal Blood Sampling Site for Point of Care Lactate Assessment using the handled Lactate-Pro 2 device
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Athletic Injuries, Soccer Injury
FIFA 11+ Warm-Up and Injury Risk Classification in Youth Amateur Soccer Players
This randomized controlled trial evaluated whether an eight-week, supervised FIFA 11+ neuromuscular warm-up program improves multifactorial injury risk classification, functional performance, and time-loss injury incidence in…
- Conditions
- Athletic Injuries, Soccer Injury, Lower Extremity Injury, Sprains and Strains
- Trial name
- NCT07713004
- Testing
- FIFA 11+ Neuromuscular Warm-Up Program, Routine Warm-Up
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
ACL Injury, ALL
ACL Reconstruction With/Without ALL Reconstruction
This study will compare Anterior Cruciate Reconstruction with or without Anterolateral Ligament Reconstruction in patients with ACL injury.
- Trial name
- NCT05461625
- Testing
- ACL reconstruction, ALL anatomic, ALL tenodesis
- Where
- Poland
- Volunteers
- 762 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Healthy, Chronic Ankle Instability, CAI
Relationship Between Muscle Strength and Balance
This study aims to examine the relationship between lower extremity muscle strength and balance and to compare these parameters between healthy individuals and individuals with lower extremity injuries.
- Conditions
- Healthy, Chronic Ankle Instability, CAI, Anterior Cruciate Ligament Injury, Muscle Strengh
- Trial name
- NCT07419750
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Biruni University
Orthopedic Disorders, Injury of Anterior Cruciate Ligament
Injection Pressure & Adductor Canal Block
This is a prospective, randomized, single-blinded human clinical trial that will examine how injection pressure influences the spread of a given volume of injectate in the adductor canal, during adductor canal nerve block.
- Trial name
- NCT02563990
- Testing
- High Pressure Injection, Low Pressure Injection
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Miami
Anterior Cruciate Ligament Injuries, Meniscus Lesion
The Effect Of Addıtıonal Surgery On Muscle Strength, Proprıoceptıon And Balance In Anterıor Crucıate Lıgament Surgery
Meniscal tears and RAMP lesions are frequently seen together with ACL injuries. The aim of this study was to evaluate the effects of meniscus repair and RAMP lesion repair ACL reconstruction surgery in terms of muscle strength…
- Trial name
- NCT06319040
- Testing
- Muscle strength measurement, Knee joint proprioception, Balance
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medipol University
Hip Dysplasia
The Influence of Hip Replacement on Lower Extremity Hemodynamics in Crowe IV Hip Dysplasia Patient
Explore the influence of hip replacement on lower extremity hemodynamics in Crowe Ⅳ hip dysplasia patient.
- Trial name
- NCT04157842
- Testing
- total hip replacement with subtrochanteral osteotomy, total hip replacement with no osteotomy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Athletes With Previous Lateral Ankle Sprain(s)
The Spraino Pilot Trial
This pilot study will establish the preliminary effect and safety of using Spraino® to prevent lateral ankle sprains amongst athletes competing in indoor sports at sub-elite level, with a one-year follow-up.
- Trial name
- NCT03311490
- Testing
- Spraino
- Where
- 2 sites in Denmark
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Spraino
Lower Limb Amputation Above Knee (Injury)
The CYBERnetic LowEr Imb coGnitive Ortho-prostheis Plus Plus, 2nd Clinical Study (CLs++)
The aim of the project is to evaluate the efficacy of the Cyberlegs X-leg in people with a unilateral transfemoral (above the knee joint) and transtibial (under the knee joint) amputation.
- Trial name
- NCT04129853
- Testing
- Cyberlegs Xleg
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Hemorrhage, Fracture Femur
Comparative Use of Tranexamic Acid Intravenous and Topical Application in Intertrochanteric Fractures With PFNA
An intertrochanteric (ITF) trochanteric fracture of the femur is an exclusively extra capsular fracture in which the fracture line extends from the greater trochanter to the lesser trochanter.
- Trial name
- NCT04696224
- Testing
- Tranexamic acid, Saline solution
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Anterior Cruciate Ligament Injuries, Lower Extremity Problem
Knowledge Translation Intervention for ACL Injury Prevention Program in Youth Soccer
Anterior cruciate ligament (ACL) injuries of the knee are common in youth soccer players, and show an even higher prevalence in female soccer players.
- Trial name
- NCT05442879
- Testing
- Knowledge Translation Intervention, Educational handout
- Where
- United States
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Lymphedema of Leg, Lymphedema
Inspiratory and Calf Muscles Training in Patients With Leg Lymphedema
Lymphedema results in the accumulation of protein-rich fluid in the subcutaneous tissue as a result of the failure of the lymphatic system, which returns water and protein in the interstitial spaces to the bloodstream.
- Conditions
- Lymphedema of Leg, Lymphedema, Exercise
- Trial name
- NCT05609526
- Testing
- Compression Therapy, Inspiratory muscle training, Calf muscle exercise training
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Ankle Sprain, Ankle Instability
Auto-regulated Blood Flow Restriction in Athletes With Recurrent Ankle Sprain
Ankle injuries, especially lateral ankle sprains, are prevalent in physically active individuals. Blood Flow Restriction Training (BFRT) has emerged as a promising method, employing partial arterial occlusion and full venous…
- Trial name
- NCT06962943
- Testing
- Auto-regulated Blood Flow Restriction Training, Non-regulated Blood Flow Restriction Training, Control group
- Where
- United Arab Emirates
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Stroke
Stroke Rehabilitation Program Based on a Powered Lower Extremity Exoskeleton in Chile
This research will study the effects of a rehabilitation program assisted by a powered lower extremity exoskeleton in patients after stroke.
- Trial name
- NCT04228224
- Testing
- Robot-assisted training with a lower extremity powered exoskeleton (H3 Exoskeleton, Spain), Conventional gait rehabilitation
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
Ankle Sprains
Validation of the Identification of Functional Ankle Instability (IdFAI) in Italian
The purpose of the study is actually the translation, cultural adaptation and psychometric validation in the Italian Version of the Identification of Functional Ankle Instability (IdFAI) English Version for use in outpatient…
- Trial name
- IdFAI-I (NCT04516980)
- Testing
- Questionnaires administration
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Padova
Q-angle, Plantar Loading Patterns
Regional Associations Between Q-Angle and Plantar Loading in Active Young Adults
This observational study aims to examine the association between Q-angle and plantar loading characteristics in physically active young adults.
- Trial name
- NCT07500597
- Testing
- Q-angle and plantar pressure assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Harran University
Edema Leg, Venous Insufficiency of Leg
Discovering the Effect of Venous Insufficiency on Nocturia (DEVINe)
Nocturia, or waking during the night to pass urine, is a multifactorial disease. An important cause of nocturia are peripheral edema due to accumulation of fluid in the lower limbs.
- Conditions
- Edema Leg, Venous Insufficiency of Leg, Nocturia, Bio-Impedance Measurements
- Trial name
- DEVINe Pilot (NCT03928197)
- Testing
- Tilt Test, Inbody S10, Tape measurements
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Knee Injuries
Non- vs Partial Controlled Weightbearing After Multiple Knee Ligament Reconstruction
This is a prospective randomized controlled trial with the purpose to determine if patients undergoing isolated posterior cruciate ligament (PCL) reconstruction, or isolated medial collateral ligament (MCL) reconstruction, or…
- Trial name
- NCT05073276
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Twin Cities Orthopedics
Injury
Stories to Educate Patients With Ankle, Foot, and Knee Injuries
Study will test the use of narratives on patient satisfaction and translation of an evidence-based approach to the use of X-rays for leg injuries in the Emergency Department (ED).
- Trial name
- NCT01810523
- Testing
- Narrative, Control
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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