Clinical trials: Lower Extremity
Low Back Pain, Leg Pain
Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis
The purpose of this multi-center, randomized, clinical study is to establish the safety and effectiveness of the TOPS™ System, used following decompression, in the treatment of lower back and leg pain with, or without spinal…
- Conditions
- Low Back Pain, Leg Pain, Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- NCT00405691
- Testing
- "TOPS System" - Total Posterior Arthroplasty Implant
- Where
- 16 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Impliant, Ltd.
Leg Injuries
Effects of Foot Strengthening on the Incidence of Injuries in Long Distance Runners
The main objective of this trial is to investigate the effects of a training protocol for the foot and ankle complex on the prevalence of running related injuries on long distance runners.
- Trial name
- NCT02306148
- Testing
- Foot and ankle strengthening
- Where
- Brazil
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Diabetic Foot Ulcers
Omeza Products in Combination With Standard of Care for the Treatment of Diabetic Foot Ulcers
This study is to evaluate the efficacy of OCM™ used in combination with off-loading devices for the treatment of diabetic foot ulcers.
- Trial name
- NCT05417425
- Testing
- Omeza collagen matrix, Omeza lidocaine lavage, Omeza skin protectant
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Omeza, LLC
Local Hypoalgesia, Distal Hypoalgesia
Exercise-Induced Hypoalgesia Differences Between Upper and Lower Limbs Resistance Training Interventions
This randomized controlled trial with healthy subjects aims to compare exercise-induced hypoalgesia among three groups: one utilizing a lower limb resistance training intervention, another using an upper limb resistance training…
- Conditions
- Local Hypoalgesia, Distal Hypoalgesia, Resistance Training, Pressure Pain Thresholds
- Trial name
- NCT06765486
- Testing
- Lower limb resistance training, Upper limb resistance training
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Knee Injuries, Anterior Cruciate Ligament Injuries
Effect of Neuromuscular Warm-up on Injuries in Female Athletes
The goal of the study is to determine effect of coach-led neuromuscular warm-up on non-contact, lower extremity (LE) injury rates among female athletes in a predominantly non-white public high school system.
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Injuries, Ankle Injuries, Lower Extremity Injuries
- Trial name
- NCT01092286
- Testing
- neuromuscular warm-up
- Where
- United States
- Volunteers
- 1,653 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Joint Instability, Ankle Sprains
Functional Electrical Stimulation in Chronic Ankle Instability
Individuals with chronic ankle instability (CAI) display neuromuscular deficits such as altered control of posture and gait when compared with healthy controls.
- Conditions
- Joint Instability, Ankle Sprains, Sport Injury
- Trial name
- ESCAIP (NCT04314960)
- Testing
- Functional electrical stimulation device (NESS L300Plus, Bioness, Valencia, CA)
- Where
- Israel
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Shmuel Springer
Sport Injury, Anterior Cruciate Ligament Injury
Definition of Biomechanical Indices Measurable During Sport Movements for the Prevention of Primary and Secondary ACL Injury
The aim of the study is to define a set of quantitative parameters related to articular biomechanics, which will be evaluated during some specific motor tasks.
- Conditions
- Sport Injury, Anterior Cruciate Ligament Injury, Biomechanical; Lesion
- Trial name
- BIOS-ACL (NCT03840551)
- Testing
- Biomechanical analysis with inertial sensors (XSENS) and motion capture (BTS)
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Groin Strain
Comparative Effects of Copenhagen and Holmich Exercises in Hip Adductor
Groin pain that relates to the adductor muscle usually represents in the groin region specifically in superior internal thigh. Tears or strains may happen within the muscles itself, tears or strains mainly occurs at…
- Trial name
- NCT05970003
- Testing
- Copenhagen exercises, Holmich exercises
- Where
- Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Osteoarthritis
Visual Feedback Non-weight Bearing Exercise on the Elderly With Knee Osteoarthritis.
Degenerative knee arthritis is the most common chronic arthritis disease. Once the elderly suffer from this disease, it will accelerate the loss of body function and autonomy.
- Trial name
- NCT04919486
- Testing
- visual feedback with non-weight bearing exercise, elastic band exercise
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Muscle Contractile Properties, Resistance Exercise
Foot Progression Angle and Leg Press: Vastus Medialis Contractile Responses
This study examined the interaction between rotational foot positioning during leg press and individuals' habitual foot progression angle (FPA) phenotype on the acute contractile response of the vastus medialis muscle
- Conditions
- Muscle Contractile Properties, Resistance Exercise, Foot Progression Angle
- Trial name
- NCT07546851
- Testing
- Congruent Foot Position Leg Press, Incongruent Foot Position Leg Press
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Giresun University
Neuromuscular Control
Distal Thigh Compression Garment Improves Knee Control and Safety Perceptions During Single Leg Triple Hop for Distance
This study measured knee frontal plane projection angle (FPPA) and sports safety and performance perceptions of female athletes during a single leg triple hop for distance for 3 conditions (standard knee sleeve, no device and…
- Trial name
- NCT04863937
- Testing
- Distal Thigh Compression Garment, Knee Sleeve
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Spalding University
Lipedema, Obesity & Overweight
Ultrasonographic Evaluation and Pedobarographic Correlation of Lower Extremity Muscles in Lipedema Patients
The primary aim of this study is to evaluate the lower extremity muscle structure, lower extremity alignment, and foot posture in lipedema; secondly, to reveal the chain relationship and biomechanical problems that may be…
- Trial name
- PODUSG (NCT07724483)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Foot Diseases, Ankle Disorders Injuries
Baropodometric Assessment of the Podiatric Profile of Nursing Students in Clinical Settings
The nursing profession is highly affected by exhausting positions, namely prolonged standing and walking, which are the second work-related factor hindering foot health.
- Trial name
- NCT05197166
- Testing
- Acute Clinical Settings
- Where
- Portugal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Enfermagem de Coimbra
Landing Error Scoring System (LESS)
The Effect of Dynamic Taping to Improve the Landing Strategy in Athletes.
This study will be conducted in three years: In the first year, we would recruit male and female high school soccer athletes to observe the effect of dynamic taping on landing error scoring system under fatigue status.
- Trial name
- NCT05288296
- Testing
- dynamic taping
- Where
- Taiwan
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pain, Ankle Injuries
Erector Spinae Plane Block and Ankle and Foot Surgery
Regional anesthesia is commonly used in orthopedic and surgical procedures in ankle and foot surgery to manage pain. The ultrasound-guided nerve block is a safe and effective regional anesthesia technique that provides effective…
- Trial name
- NCT05708742
- Testing
- Ultrasound, Bupivacaine Hydrochloride, saline solution
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Elders
Turkish Version of Lower Extremity Functional Scale in Elders
This study was conducted in order to analyze the validity and reliability, and psychometric properties of the Turkish version of the Lower Extremity Functional Scale (LEFS-T) in elder adults.
- Trial name
- NCT05035329
- Testing
- Outcome measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
ACL - Anterior Cruciate Ligament Rupture
Assessment of NEURO-K-STARTS Following Primary Anterior Cruciate Ligament (ACL) Reconstruction
Anterior cruciate ligament (ACL) reconstruction is the major treatment option for ACL injuries. Despite this, recurrence rates are high.
- Trial name
- NEURO-K-STARTS (NCT07659613)
- Testing
- NEURO-K-STARTS
- Where
- France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Anterior Cruciate Ligament, Injuries
Arabic Version of Marx Activity Rating and Knee Stability in Sports/Cutting-Pivoting Ability Scales
Anterior cruciate ligament (ACL) injuries are among the most common knee ligament injuries, causing joint instability and impairments.
- Trial name
- NCT05470790
- Testing
- patient reported outcome measures
- Where
- Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Lower Extremity Deep Venous Thrombosis
Comparison of Subcutaneous Heparin and Enoxaparin for Deep Venous Thrombosis (DVT) Prophylaxis in Surgical Intensive Care Patients
Study hypothesis: Subcutaneous enoxaparin is more effective than subcutaneous heparin in preventing the development of DVT in the general surgical intensive care unit population.
- Trial name
- NCT01325779
- Testing
- heparin, enoxaparin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lisa Louwers
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