Clinical trials: Low-Level Light Therapy
Low Level Laser Therapy, Acne Vulgaris
Low Level Laser Versus Polarized Light in the Treatment of Acne Vulgaris
The present study is designed to compare clinically the therapeutic applications between low level laser therapy (excimer laser) and non-laser polarized light (Bioptron prol) in the treatment of Acne vulgaris.
- Trial name
- NCT06867276
- Testing
- Excimer laser, Bioptron Pro 1
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Chronic Low Back Pain, After Lumbar Spine Surgery
Efficacy of Cognitive Functional Therapy in Individuals With Chronic Low Back Pain After Spinal Surgery
Chronic low back pain after spinal surgery is a complex and disabling condition influenced by biopsychosocial factors. Cognitive Functional Therapy (CFT) is a promising intervention targeting these multidimensional aspects.
- Conditions
- Chronic Low Back Pain, After Lumbar Spine Surgery, Failed Back Surgery Syndrome (FBSS)
- Trial name
- NCT07576062
- Testing
- CFT
- Volunteers
- 90 people
- Sponsor
- Centro Universitário Augusto Motta
Burning Mouth Syndrome, Low Level Laser Therapy
Photobiomodulation Therapy vs. Alpha-Lipoic Acid in Burning Mouth Syndrome Treatment
The aim of this study was to evaluate the efficacy of photobiomodulation therapy and alpha-lipoic acid in the treatment of burning mouth syndrome by symptom assessment with visual analogue scale.
- Trial name
- NCT07381361
- Testing
- Low Level Laser Therapy, Alpha Lipoic Acid
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Lu Jiang
Breast Cancer, Skin Cancer
Safety Study Using Photodynamic Therapy Light Therapy for Patients With Chest Wall Progression of Breast Cancer and Satellite Metastases of Melanoma
This research is intended to explore a new approach to therapy when breast cancer recurs in the skin. The treatment, known as continuous low-irradiance photodynamic therapy, or CLIPT, has shown great promise in animal studies.
- Trial name
- CLIPT (NCT00862901)
- Testing
- CLIPT patch
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Tufts Medical Center
Orthodontics, Root Resorption
Effects of PBM on Fixed-appliance Orthodontic Patients
The aim of this study is to investigate the effects of photobiomodulation therapy (PBM) on the dental and periodontal health of patients undergoing fixed-appliance orthodontic treatment, including orthodontically induced root…
- Trial name
- NCT06199674
- Testing
- photobiomodulation therapy, orthodontic fixed-appliance
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
COVID-19, Respiratory Failure
Photobiomodulation Therapy Combined With Static Magnetic Field in Patients With COVID-19
Coronavirus disease 2019 (COVID-19) is a disease caused by a novel coronavirus called SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).
- Trial name
- NCT04386694
- Testing
- Active PBMT/sMF
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Muscular Injury
Effect of Light-emitting Diode (LED) Photobiomodulation Therapy on Muscular Fatigue in University Handball Athletes
Introduction: Low-intensity laser therapy (LBI) is a therapeutic modality with a large number of clinical studies in recent years, taking into account its effectiveness in tissue repair, pain control and, more recently, to…
- Trial name
- NCT03972007
- Testing
- Fotobiomodulation
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Laser Therapy, Urinary Incontinence,Stress
Pilates Method and/or Photobiomodulation in Women With Stress Urinary Incontinence
The present study is a clinical intervention applied to patients with urinary incontinence, with the intention of verifying the effects of the Pilates method associated or not with photobiomodulation with static magnetic field.
- Conditions
- Laser Therapy, Urinary Incontinence,Stress, Pilates Method
- Trial name
- PBMT-IUE (NCT05096936)
- Testing
- Pilates, Photobiomodulation
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Universidade de Caxias do Sul
Dry Eye Syndromes, Meibomian Gland Dysfunction
Mechanisms of Light-based Therapies for Dry Eye Disease
Dry eye disease is a common condition affecting millions worldwide and costing millions in healthcare due to reduced work productivity and quality of life.
- Trial name
- MOLT (NCT06004895)
- Testing
- Actual IPL, LLLT
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Aston University
Myopia, Randomized Controlled Trial (RCT)
The Rebound Effect on Repeated Low-Level Red Light Therapy for Myopia
Myopia is a global public health issue, projected to affect 49.8% of the world population by 2050, increasing risks of cataracts, glaucoma, macular degeneration, and retinal detachment.
- Trial name
- NCT07748546
- Testing
- Repeated low-level red light (RLRL) therapy
- Volunteers
- 159 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Cataract Surgery, Eye Dryness
Low-level Light Therapy Versus Intense Pulsed Light to Prevent Iatrogenic Dry Eye Disease After Cataract Surgery
Dry eye disease (DED) is a frequent ocular surface disease (OSD) of multifactorial origin, characterised by disruption of tear film homeostasis and associated with ocular discomfort and/or visual disturbance.
- Trial name
- EDACS (NCT07055022)
- Testing
- LLLT, IPL
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Clinique Trenel
Low Level Laser Therapy, Pain
Effect of the Diode Laser (940nm) on Orthodontics
To evaluate the effect of the low power density 940nm diode laser in the total relief of dental crowding during the alignment phase and the perception of pain in patients who initiate orthodontic treatment.
- Conditions
- Low Level Laser Therapy, Pain, Crowding, Tooth
- Trial name
- NCT05469451
- Testing
- Low level laser therapy
- Where
- Colombia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria CIEO
High-level Rugby Athletes, Performance
Photobiomodulation Therapy in a Field Test With High-level Rugby Players
Background/Aim: While growing evidence supports the use of photobiomodulation therapy (PBMT) for performance and recovery enhancement, there have only been laboratory-controlled studies.
- Conditions
- High-level Rugby Athletes, Performance, Recovery
- Trial name
- NCT02588768
- Testing
- Photobiomodulation therapy (Phototherapy)
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Breast Cancer, Radio Dermatitis
Photobiomodulation in Radiodermatitis in People With Breast Cancer
Most breast cancer patients undergoing radiotherapy develop radiodermatitis, making it one of the most prevalent adverse events during cancer treatment.
- Trial name
- NCT06990165
- Testing
- Photobiomodulation
- Where
- 2 sites in Brazil
- Volunteers
- 148 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Vulvar Vestibulitis, Vestibulodynia
Cold Laser: A Modality to Promote Vulvar Healing and Pain Relief
The objectives of this pilot study are to demonstrate effectiveness of application of the Erchonia Laser (manufactured by Erchonia Corporation),a non-invasive, non-significant risk low level laser red diode light therapy device…
- Trial name
- NCT02204319
- Testing
- Cold laser
- Volunteers
- 10 people
- Sponsor
- ProHealth Care, Inc
Weight Loss
Study to See How Low Level Laser Light Affects Subcutaneous Fat Around the Hips and Waist
The purpose of this pilot study is to demonstrate the anatomical modulation of subcutaneous fat across the waist and hips that occurs through application of the Erchonia® ML Scanner (MLS) Laser manufactured for non-invasive body…
- Trial name
- NCT01292564
- Testing
- Erchonia MLS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Erchonia Corporation
Wound Heal, Vestibular Abnormality
Comparison of Diode Laser-Assisted Vestibuloplasty And Conventional Vestibuloplasty
Randomized controlled parallel designed clinical study aimed to compare vestibule depth gain and dimensional changes of wound area in individuals who underwent vestibule deepening surgery using diode laser and conventional…
- Conditions
- Wound Heal, Vestibular Abnormality, Low-level Light Therapy, Surgical Wound
- Trial name
- NCT05252260
- Testing
- Diode Laser, Conventional Surgery, Low level laser therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Photobiomodulation Therapy
Photobiomodulation and Implant Stability
Objective: The aim of the present study was to address the following questions: does photobiomodulation therapy (PBMT) improve implant stability and affect microbiota around dental implants in the early stage of osseointegration.
- Trial name
- low-laser (NCT04495335)
- Testing
- photobiomodulation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- T.C. Dumlupınar Üniversitesi
Diabetic Foot Ulcer
Blue Light Photobiomodulation Therapy on Neuroischemic Patients
This is a pilot case/control clinical study on a group of outpatients with diabetic foot lesions aiming to verify the efficacy and safety of the Blue light photobiomodulation therapy with EmoLED medical device, in addition to…
- Trial name
- HERMES (NCT04831606)
- Testing
- debridement, Offloading, Advanced dressing
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Emoled
Head and Neck Cancer, Trismus
Photobiomodulation and Sonophoresis Improving Jaw Mobility and Quality of Life Among Head and Neck Cancer Survivors
Head and neck cancer originate from the several different anatomical subsites especially the squamous cell carcinoma. This involves mainly Oropharynx, Hypopharynx, and Larynx.
- Trial name
- NCT04082793
- Testing
- Photobiomodulation therapy with mandibular exercises, Sonophoresis with mandibular exercises
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel