Clinical trials: Long-term Sedation for Mechanical Ventilation
Intubated Requiring Sedation for Greater Than 48 Hours
AnaConDa Long Term Sedation Study
Heavy sedation or sleep is a common problem within the intensive care unit (ICU) using our standard intravenous medications. This commonly leads to confusion, low blood pressure, slow wake up and removal of the artificial…
- Trial name
- VALTS (NCT01983800)
- Testing
- Isoflurane, Propofol/midazolam
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Mechanical Ventilation, Complication
Midazolam Used Alone or Sequential Use of Midazolam and Propofol/Dexmedetomidine in Mechanically Ventilated Patients
The purpose of this study was to evaluate effects, safety and cost of midazolam used alone or sequential use of midazolam and propofol/dexmedetomidine for long-term sedation in critically ill, mechanically ventilated patients.
- Conditions
- Mechanical Ventilation, Complication, Delirium
- Trial name
- NCT02528513
- Testing
- midazolam, Fentanyl, propofol
- Where
- China
- Volunteers
- 240 people
- Sponsor
- West China Hospital
Poisoning by Inhaled Anaesthetic, Fluoride Poisoning
Sevoflurane- Safety in Long-term Sedation Procedures
Patients needing intensive care often require sedative drugs to reduce anxiety and agitation during ventilator care and invasive therapeutic and diagnostic procedures.
- Conditions
- Poisoning by Inhaled Anaesthetic, Fluoride Poisoning, Recovery From Sedation, Renal Function
- Trial name
- NCT01802255
- Testing
- Sevoflurane, Midazolam
- Where
- Spain
- Sponsor
- F Javier Belda
Long-term Sedation for Mechanical Ventilation, Critically Ill Intensive Care Unit Patients
Remimazolam vs Propofol for Long-Term Sedation in Mechanically Ventilated ICU Patients
This multicenter, randomized, controlled, non-inferiority trial is designed to determine whether remimazolam is non-inferior to propofol for prolonged sedation in adult ICU patients requiring mechanical ventilation for ≥48 hours.
- Trial name
- RePro-ICU (NCT07880548)
- Testing
- Remimazolam group, Propofol group
- Where
- 21 sites in China
- Volunteers
- 274 people
- Sponsor
- Sun Yat-sen University