Clinical trials: Locomotor Activity
Parkinson's Disease
Effects of RAC With Locomotion Training on Cortical Excitability and Behavior in Patients With PD
In this study, 51 subjects include 17 freezers,17 non-freezers and 17 aged-matched healthy subjects will be recruited. We will compare the cortical excitability, gait performance, and stepping-in-place performance before and…
- Trial name
- NCT03656796
- Testing
- Treadmill training with auditory cues, Treadmill training without auditory cues
- Where
- Taiwan
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Traumatic Brain Injury, Gait Disorders, Neurologic
Effect of High-Intensity Gait Training Using a Treadmill on Locomotion Recovery in Traumatic Brain Injury Patients
The project will consist of subjects who have suffered Traumatic Brain Injury (TBI) and who are able to ambulate on treadmill with or without a harness system.
- Trial name
- NCT05622786
- Testing
- HIGT - physical rehab, Low intensity physical therapy
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Aging, Pain, Acute
Effects of Acute Pain on Motor Learning in Young vs Older Adults
To date, the effects of pain on motor learning have not been thoroughly investigated, particularly in older adults. Broadly, the purpose of this research is to investigate the impact of acute pain on locomotor learning and its…
- Conditions
- Aging, Pain, Acute, Cognitive Decline, Motor Activity
- Trial name
- NCT05471557
- Testing
- pain delivery
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Unilateral Amputation of the Lower Limb
Virtual Reality Applied to the Evaluation and Rehabilitation of Locomotion - Study of Tolerance in the Lower Limb Amputee
The adaptability of the locomotor activity allows to face all the modifications of the immediate environment met in the daily activities.
- Trial name
- REVA (NCT05635799)
- Testing
- Analysis of walking on flat ground, Hospital Anxiety Disorder Questionnaire, Analysis of walking on slopes
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Flatfoot
The Influence of Rehabilitation Program on Postural Control, Balance and Gait in Children With Flatfoot
"Idiopathic flat foot is a common condition in children and adolescents. After loading, the heel is adjusted in valgus, the medial longitudinal arch of the foot flattens, and the forefoot is positioned at abducted.
- Trial name
- NCT04840017
- Testing
- rehabilitation exercise
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Multiple Sclerosis
The Neural Mechanisms of Split-belt Treadmill Adaptation in People With Multiple Sclerosis
Majority of people with multiple sclerosis experience difficulty with balance and mobility, leading to an increased risk of falls.
- Trial name
- NCT05878873
- Testing
- Split-belt Treadmill, Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Lower Limb Amputation
Walking Strategies in Usual Locomotion of Lower Limb Amputees
Amputation is a life-altering event with an immediate and obvious effect on daily life activities and quality of life. Asymmetrical movements of the lower limbs and compensatory strategies during walking are associated with an…
- Trial name
- STRAAL (NCT05420623)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- FondationbHopale
Peripheral Arterial Disease
Locomotion and Global Positioning System in Arterial Disease
The maximal walking distance (MWD) performed on treadmill (TT) remains the gold standard in estimating the walking capacity of patients suffering from peripheral arterial disease (PAD) with intermittent claudication, although…
- Trial name
- Starter-GPS (NCT00485147)
- Testing
- Recording of GPS during a free walking in a public park
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Chronic Low Back Pain (non-specific, Uncomplicated), Walking
Exploring Locomotion Behavior of Chronic Non-Specific Low Back Pain (cNSLBP) Patients While Walking Through Apertures in Different Configurations: Influence of Environmental and Social Factors.
The biomechanical parameters studied in chronic non-specific low back pain (cNSLBP) patients in a locomotion task have so far focused on straight line walking.
- Trial name
- PERL3 (NCT06644053)
- Testing
- Quantified analysis of walking during a crossing task through different horizontal openings
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Premature Birth
EEG and NIRS in Preterm Infants
Experimental cross-sectional study of a single application (vojta therapy or massage) in preterm and non-preterm infants to test whether there are differences in brain activation and oxygenation that occur with both techniques…
- Trial name
- NCT05410340
- Testing
- Vojta Therapy, Massotherapy
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Postural Balance
Evaluation of Foot Mechanical Information on Static Task and Locomotion
Sensory foot integration is evaluated by foam under feet both in research and clinical contexts. However, there is no norm defined regarding foam characteristics and this evaluation is mostly performed using a static task.
- Trial name
- NCT05170750
- Testing
- Foams, Foam / Orthopedic insole
- Where
- 2 sites in France
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Child Development
Dual Tasking in Children With Cerebral Palsy and Healthy Children: an EEG Study
Simultaneous execution of motor and cognitive tasks is embedded in the daily life of children. An EEG study will be conducted on healthy children and children with cerebral palsy to study the neural correlates during dual tasking…
- Trial name
- PRALOC (NCT04634292)
- Testing
- EEG
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Traumatic Amputation of Lower Extremity
Characterizing Ankle Function During Sloped Locomotion for Prosthesis Development
The proposed study aims to characterize biological ankle joint function during walking and running on slopes in order to further develop advanced powered ankle-foot prostheses.
- Trial name
- NCT01784003
- Testing
- Powered ankle-foot prosthesis
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Cybersickness
Investigation of the Effects of Two Types of Locomotion in the Virtual Environment
Virtual Reality (VR) is a technology that enables individuals to engage in a computer-generated, three-dimensional (3D) environment by utilizing specialized electronic equipment.
- Trial name
- NCT06206213
- Testing
- Assessment of two different locomotion types.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Mobility Impairment, Community Dwelling Older Adults
Motor Imagery and Turning Practice to Improve Mobility: Pilot Trial
The goal of this clinical trial is to evaluate whether combining in-person turning practice with home-based Motor Imagery Therapy (MIT) is feasible and may improve mobility in community-dwelling older adults aged 65 years and…
- Trial name
- MI-TURN (NCT07705360)
- Testing
- Motor Imagery Therapy, Stress Management Education, Locomotor Turning Practice
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boise State University
Healthy, Spastic Hemiparesis
Soleus Loading Response During Walking
Stroke survivors experience motor deficits, weak voluntary muscle activations, and low weight-bearing capacity that impair ambulation.
- Conditions
- Healthy, Spastic Hemiparesis, Stroke
- Trial name
- NCT05436366
- Testing
- Soleus loading response in able-bodied participants, Soleus loading response in participants with hemiparesis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Victor H. Duenas
Hip Osteoarthritis, Indication for Total Hip Replacement
Evaluation of Locomotor Activity Before and After Total Hip Replacement in Patients With Hip Osteoarthritis.
The investigators believe that the application of non-linear methods of analysis using the ganglion and neural network technique will make it possible to analyse all of the complex data obtained in patients with hip…
- Trial name
- NCT02042586
- Testing
- Analysis of movement before total hip replacement, Analysis of movement after total hip replacement
- Where
- France
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Craniocerebral Trauma
The Acute Effect of Boxing on Balance, Neuropsychological, and Visual Functions
Prior research has investigated the effect of repetitive head trauma as it relates to physiological and psychological function. Boxing is one particular sport which predisposes athletes to a large amount of head impacts.
- Trial name
- NCT02442882
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Spinal Cord Injury
Sympathetic-Somatomotor Coupling in Human Spinal Cord Injury
Significance: The long term objective of this study is to improve physical therapy and fitness programs in people with spinal cord injury.
- Trial name
- NCT02115685
- Testing
- Treadmill Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Multiple Sclerosis
Biomechanical Characterization of the Locomotion in Multiple Sclerosis Patients
Multiple sclerosis (MS) is an inflammatory chronic disease of the central nervous system. Patients are suffering from balance and gait impairments at the early stage of the disease.
- Trial name
- WALKING-SEP (NCT03756142)
- Testing
- Motion Analysis
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University