Clinical trials: Locomotor Activity
Simulation of Weightlessness by Anti-Orthostatic Long Term Bed Rest
Toulouse Male Long Term Bed Rest 2001-2002
Microgravity during space flight induces physiological changes that affect astronauts' health and performance. Space flight simulations such as prolonged bed rest can mimic some of these changes and provide study conditions that…
- Trial name
- NCT00311571
- Testing
- Ethidronate, Physical training
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre National d'Etudes Spatiales
Spinal Cord Injury
The ATLET Study: Can Subjects With Incomplete Spinal Cord Injury Learn to Walk?
The ATLET study will assess the effect of manual or robotic body-weight supported locomotor training of patients with stable motor incomplete spinal cord injury (SCI) on gait and overall ADL function as well as on estimated…
- Trial name
- ATLET (NCT00854555)
- Testing
- Locomotor training with robot, Locomotor training with manual assistance
- Where
- 2 sites in Norway
- Volunteers
- 44 people
- Sponsor
- North Norway Rehabilitation Center
Stroke
Robotic Exosuit Augmented Locomotion (REAL) in the Clinic and Community
Previous studies of the exosuit technology have culminated in strong evidence for the gait-restorative effects of soft robotic exosuits for patients post-stroke by means of substitution for lost function.
- Trial name
- REAL-m (NCT05315310)
- Testing
- Soft Exosuit
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Boston University Charles River Campus
Parkinson's Disease
Effects of RAC With Locomotion Training on Cortical Excitability and Behavior in Patients With PD
In this study, 51 subjects include 17 freezers,17 non-freezers and 17 aged-matched healthy subjects will be recruited. We will compare the cortical excitability, gait performance, and stepping-in-place performance before and…
- Trial name
- NCT03656796
- Testing
- Treadmill training with auditory cues, Treadmill training without auditory cues
- Where
- Taiwan
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Traumatic Brain Injury, Gait Disorders, Neurologic
Effect of High-Intensity Gait Training Using a Treadmill on Locomotion Recovery in Traumatic Brain Injury Patients
The project will consist of subjects who have suffered Traumatic Brain Injury (TBI) and who are able to ambulate on treadmill with or without a harness system.
- Trial name
- NCT05622786
- Testing
- HIGT - physical rehab, Low intensity physical therapy
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Parkinson Disease, COPD
The ADAPT-study: Measuring Physical Performance Using Wearable Sensors in Parkinson's Disease and COPD (ADAPT)
The aim of this study is to investigate whether a smartwatch can measure the physical capacity of patients with Parkinson's Disease and COPD in the physiotherapy practice and at home.
- Trial name
- ADAPT (NCT05756075)
- Testing
- Aerobic exercise training
- Where
- 28 sites in Netherlands
- Volunteers
- 154 people
- Sponsor
- Radboud University Medical Center
Spinal Cord Injury, Spinal Cord Injuries
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury
- Trial name
- NCT04460872
- Testing
- Testosterone Enanthate, Locomotor Training
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- North Florida Foundation for Research and Education
Aging, Pain, Acute
Effects of Acute Pain on Motor Learning in Young vs Older Adults
To date, the effects of pain on motor learning have not been thoroughly investigated, particularly in older adults. Broadly, the purpose of this research is to investigate the impact of acute pain on locomotor learning and its…
- Conditions
- Aging, Pain, Acute, Cognitive Decline, Motor Activity
- Trial name
- NCT05471557
- Testing
- pain delivery
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Unilateral Amputation of the Lower Limb
Virtual Reality Applied to the Evaluation and Rehabilitation of Locomotion - Study of Tolerance in the Lower Limb Amputee
The adaptability of the locomotor activity allows to face all the modifications of the immediate environment met in the daily activities.
- Trial name
- REVA (NCT05635799)
- Testing
- Analysis of walking on flat ground, Hospital Anxiety Disorder Questionnaire, Analysis of walking on slopes
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Flatfoot
The Influence of Rehabilitation Program on Postural Control, Balance and Gait in Children With Flatfoot
"Idiopathic flat foot is a common condition in children and adolescents. After loading, the heel is adjusted in valgus, the medial longitudinal arch of the foot flattens, and the forefoot is positioned at abducted.
- Trial name
- NCT04840017
- Testing
- rehabilitation exercise
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Multiple Sclerosis
The Neural Mechanisms of Split-belt Treadmill Adaptation in People With Multiple Sclerosis
Majority of people with multiple sclerosis experience difficulty with balance and mobility, leading to an increased risk of falls.
- Trial name
- NCT05878873
- Testing
- Split-belt Treadmill, Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Lower Limb Amputation
Walking Strategies in Usual Locomotion of Lower Limb Amputees
Amputation is a life-altering event with an immediate and obvious effect on daily life activities and quality of life. Asymmetrical movements of the lower limbs and compensatory strategies during walking are associated with an…
- Trial name
- STRAAL (NCT05420623)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- FondationbHopale
Spinal Cord Injuries
Improving Gait in Patients With Spinal Cord Injuries
This study is part of a larger clinical trial that examines the potential of a 12-week treadmill-training program to improve walking in patients with spinal cord injuries (SCIs).
- Trial name
- NCT00060983
- Testing
- Body weight supported locomotor training, Functional electrical stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stroke
Robot-Assisted Stair Climbing Training
Stair climbing up and down is an essential part of everyday's mobility. Physiotherapy is focused on muscle strengthening, real floor walking and stairs climbing tasks, but these methods do not stress in terms of intensity…
- Trial name
- RASCT (NCT03566901)
- Testing
- G-EO System, Conventional Physiotherapy
- Where
- 2 sites in Italy
- Volunteers
- 72 people
- Sponsor
- Universita di Verona
Cerebral Palsy
Short-Burst Interval Treadmill Training Cerebral Palsy
Ambulatory children with cerebral palsy (CP) walk predominately in low intensity stride rates with little variability, thus limiting their walking activity and ability to participate in daily life.
- Trial name
- NCT04026295
- Testing
- Short Burst Interval Treadmill Training (SBLTT), Traditional Locomotor Treadmill Training (TLTT)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Kristie Bjornson
Peripheral Arterial Disease
Locomotion and Global Positioning System in Arterial Disease
The maximal walking distance (MWD) performed on treadmill (TT) remains the gold standard in estimating the walking capacity of patients suffering from peripheral arterial disease (PAD) with intermittent claudication, although…
- Trial name
- Starter-GPS (NCT00485147)
- Testing
- Recording of GPS during a free walking in a public park
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Rehabilitation, Parkinson Disease
Golden Walk as Measure of Gait Rehabilitation in Parkinson's Disease
Gait is specifically impaired in Parkinson's disease (PD). External auditory cue based on a binary rhythm tested in PD patients disappear when the stimulus is removed.
- Conditions
- Rehabilitation, Parkinson Disease, Locomotion Disorder, Neurologic, Rhythm; Abnormal
- Trial name
- NCT04706572
- Testing
- Stimulation with external auditory bio-feedback
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Parkinson Disease
Effect of L-Dihydoxyphenylserine on Locomotion, Postural Stability, and Fall Risk Reduction in Parkinson Disease
This research study is being done to determine whether treatment with L- Dihydroxyphenylserine (L-DOPS) versus placebo (an inactive substance that looks like study drug) in addition to other Parkinson Disease (PD) drugs will…
- Trial name
- NCT02812147
- Testing
- L-DOPS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Chronic Low Back Pain (non-specific, Uncomplicated), Walking
Exploring Locomotion Behavior of Chronic Non-Specific Low Back Pain (cNSLBP) Patients While Walking Through Apertures in Different Configurations: Influence of Environmental and Social Factors.
The biomechanical parameters studied in chronic non-specific low back pain (cNSLBP) patients in a locomotion task have so far focused on straight line walking.
- Trial name
- PERL3 (NCT06644053)
- Testing
- Quantified analysis of walking during a crossing task through different horizontal openings
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Premature Birth
EEG and NIRS in Preterm Infants
Experimental cross-sectional study of a single application (vojta therapy or massage) in preterm and non-preterm infants to test whether there are differences in brain activation and oxygenation that occur with both techniques…
- Trial name
- NCT05410340
- Testing
- Vojta Therapy, Massotherapy
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Salamanca