Clinical trials: Local Control Rate
Surgical Wound Infection
Local Gentamicin Application to Reduce Postoperative Infection Rate
The majority of elderly patients with a displaced fracture of the proximal femur are now treated with a hemiarthroplasty. Prosthetic joint infection is a devastating complication, and the infection rate is high in this group of…
- Trial name
- NCT01287780
- Testing
- Collagen-gentamicin sponge
- Where
- 5 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Oslo University Hospital
Analgesia, Pain, Postoperative
Comparison of Local Anesthetic Dose in Ipack Block Performed in Knee Arthroplasty Operations
The investigators research was designed as a single-center, prospective, randomized study. The patients undergoing knee artrhroplasty surgery in Istanbul University Istanbul Medicine Faculty Department of Orthopedics and…
- Conditions
- Analgesia, Pain, Postoperative, Anesthesia
- Trial name
- NCT05963139
- Testing
- Bupivacaine, Morphine Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Istanbul University
Postoperative Pain
Transversus Abdominis Plane Block Versus Local Anesthetic Infiltration for Pain Control in the Abdominal Surgery
Postoperative analgesia is an important part of the anesthetic care. According to the recent studies, multimodal analgesia can provide better analgesia \& patient satisfaction with fewer side effect.
- Trial name
- TAP (NCT02029755)
- Testing
- transversus abdominis plane block, local infiltration, Patient controlled analgesia
- Where
- Taiwan
- Volunteers
- 108 people
- Sponsor
- Taipei Medical University Hospital
Wound Infection Rate After Surgery, Impact of Wound Infection on Pain and Wound Healing
Impact of Preoperative Local Water-Filtered Infrared-A (wIRA) Irradiation on Postoperative Wound Healing
The purpose of this study is to dermine whether local-water filtered infrared-A (wIRA) irradiation can reduce postoperative wound infection.
- Trial name
- Hydrosun (NCT01654679)
- Testing
- wIRA irradiation, visible light only
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- German Research Foundation
Postoperative Pain, Arthroscopic Shoulder Surgery
Intravenous Dexamethasone Added to Dexmedetomidine After Superior Trunk Block
This prospective, randomized, placebo-controlled, triple-blind trial will evaluate the effect of adding intravenous dexamethasone to intravenous dexmedetomidine on postoperative analgesia after superior trunk block in adult…
- Conditions
- Postoperative Pain, Arthroscopic Shoulder Surgery, Regional Anesthesia
- Trial name
- STB-DEX (NCT07795281)
- Testing
- Intravenous Dexamethasone, Intravenous Dexmedetomidine, Superior Trunk Block
- Volunteers
- 70 people
- Sponsor
- Gaziantep City Hospital
Giant Cell Tumor of Bone
Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone
The purpose of the clinical study is to investigate whether the local delivery of bisphosphonate as a surgical adjuvant can decrease the chance of a giant cell tumor of bone coming back to the same location.
- Trial name
- NCT03295981
- Testing
- Zoledronic Acid
- Where
- 16 sites in United States, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Radial Artery Injury
Effect of Local Anesthesia Position of Lidocaine Injection on the Success Rate of Radial Artery Puncture Tube
Objective: To investigate the effect of lidocaine injection location on the success rate of ultrasound-guided radial artery catheterization in a single-center, randomized, controlled clinical trial.
- Trial name
- NCT06424145
- Testing
- Superior radial artery, Right side of radial artery
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Ting Xu
Humans, Anesthetics, Local
MORphine Use in the Fascia Iliaca Compartment Block With UltraSound
Appropriate management of analgesia for proximal femoral fractures is a common problem in the emergency department (ED). Side effects from morphine usage such as nausea, vomiting, respiratory depression, sedation, and obstipation…
- Conditions
- Humans, Anesthetics, Local, Morphine, Pain Management
- Trial name
- MORFICUS (NCT03846102)
- Testing
- Levobupivacaine, Acetaminophen, Morphine
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- Zuyderland Medisch Centrum
Scoliosis
Effect of Regional Anesthesia or Intravenous Infusion of Lidocaine on Morphine Use After Scoliosis Repair Surgery
The goal of the surgical correction of scoliosis is to prevent progression of the curve or progression of restrictive lung disease. After scoliosis surgery, patients experience severe pain.
- Trial name
- NCT06451562
- Testing
- Lidocaine
- Where
- Israel
- Volunteers
- 105 people
- Sponsor
- Assaf-Harofeh Medical Center
Ewing Sarcoma, Bone Neoplasms
Neoadjuvant Radiotherapy and Surgery for High-Risk Localized Ewing Sarcoma
This is a single-center, single-arm, prospective observational study to evaluate the long-term local control rate, safety, and efficacy of preoperative neoadjuvant radiotherapy (36-45 Gy) followed by sequential radical surgery…
- Trial name
- NCT07620431
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Peking University People's Hospital
Esophageal Cancer, Esophageal Squamous Cell Carcinoma
Brachytherapy With Radiotherapy and Immunotherapy: Guided HDR Trial in Esophageal Squamous Cell Carcinoma
The goal of this clinical trial is to learn if adding high-dose-rate (HDR) brachytherapy can improve outcomes in patients with locally advanced esophageal squamous cell carcinoma (ESCC) who have already received external beam…
- Trial name
- BRIGHT-ESCC (NCT07152678)
- Testing
- Nivolumab (240 mg), Brachytherapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Local Control Rate, Side Effect
Proton Beam Therapy for Unresectable Liver Metastasis
The investigators performed the present study to evaluate the role of proton beam therapy for liver metastasis which is unresectable and unsuitable for radiofrequency ablation (RFA) in terms of local control and safety.
- Trial name
- NCT04456621
- Testing
- PBT
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Samsung Medical Center
Laryngeal Neoplasms, Malignant Neoplasm of Supraglottis Primary
A Multicenter, Randomized, Case-control Study of Unilateral vs Bilateral Neck Dissection for cN0 Supraglottic Laryngeal Cancer
Supraglottic laryngeal carcinoma patients with clinically negative neck (cN0) will be randomized divided into two groups. Patients in case group will undergo unilateral neck dissection (II-IV) while bilateral neck dissection…
- Conditions
- Laryngeal Neoplasms, Malignant Neoplasm of Supraglottis Primary, Neck Dislocation
- Trial name
- NCT03392220
- Testing
- Unilateral Neck Dissection, Bilateral Neck Dissection
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Phthisis Bulbi
Comparison of Local Made and Imported Porous Polyethylene Orbital Implant for Enucleation in Thailand
This study wants to compare between two types of implants in enucleation. Both of them are made from porous polyethylene but have different fabricating techniques.
- Trial name
- NCT01312545
- Testing
- 3DP, Medpor
- Where
- Thailand
- Volunteers
- 105 people
- Sponsor
- Mettapracharak Hospital
Efficiency and Safey of Radial Artery Cannulation
Novel Local Infiltration Anesthesia for Radial Artery Cannulation.
This clinical trial aims to compare the pain scores and cannulation success rates of conventional, bar-shaped, and V-shaped local infiltration anesthesia in participants' radial artery cannulation.
- Trial name
- NCT05735132
- Testing
- Conventional Line-blocking, Bar-blocking, V-blocking
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
Prostate Cancer
US/MRI Fusion Local Anestesia TransPerineal Prostate Biopsies for Detection of Prostate Cancer
We are conducting a randomised trial comparing outcomes of transperineal prostate biopsies under free-hand software assisted MRI/US fusion with transrectal biopsy guide software assisted MRI/US fusion.
- Trial name
- FLAPP (NCT04797078)
- Testing
- Transperineal biopsy, Transrectal biopsy
- Sponsor
- Karolinska Institutet
Postoperative Pain
Postoperative Analgesic Effectiveness of Fascial Plane Blocks in Breast Surgery
This prospective, single-center observational study will compare postoperative pain control in adults undergoing elective breast surgery.
- Trial name
- NCT07830446
- Testing
- Rhomboid intercostal plane block, Serratus posterior superior intercostal plane block, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Anesthesia, Local, Surgery
Effect of Virtual Reality (VR) Therapy on Patients Undergoing Hand Surgery Under Ultrasound-guided Regional Anesthesia
By means of an investigator-initiated, monocentric, single-blinded, prospective, randomized controlled superiority trial, the effect of virtual reality (VR) therapy on patients undergoing ambulatory hand surgery under…
- Conditions
- Anesthesia, Local, Surgery, Hand Injuries
- Trial name
- NCT05183412
- Testing
- The Sedakit Oncomfort VR glasses (30-minutes Aqua program), Ultrasound-guided regional nerve block and hand surgery without VR glasses, Ultrasound-guided regional nerve block and hand surgery with VR glasses
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Jessa Hospital
Infection
Efficacy of Local Powder Prophylactics
Hypothesis: Directly applying antibiotic powder onto the site of surgery along with perioperative intravenous antibiotics, before closing the wound, is more effective than intravenously applied perioperative antibiotics alone in…
- Trial name
- NCT01372371
- Testing
- Vancomycin, Vancomycin and Gentamycin, Cefuroxime
- Where
- India
- Volunteers
- 1,844 people
- Sponsor
- Ganga Hospital
Local Allergic Rhinitis
Subcutaneous Immunotherapy With Dermatophagoides Pteronyssinus in Local Allergic Rhinitis
To evaluate the efficacy of an extract of Dermatophagoides pteronyssinus versus placebo in the treatment of local allergic rhinitis.
- Trial name
- ECRL1 (NCT02123316)
- Testing
- Pangramin Plus D. pteronyssinus
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Miguel Blanca Gomez