Clinical trials: Living Kidney Donation
End Stage Renal Disease
Assessment of Poles' Attitudes Towards Living Kidney Donation
The main goal of the project is to examine the public opinion on living kidney donation and to assess the knowledge of Poles in this field.
- Trial name
- NCT04789122
- Testing
- Attitude assessment
- Where
- Poland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
Renal Insufficiency, Chronic
Multi-parametric MRI Evaluation of Renal Graft Performance After Living Donor Donation.
The selection of kidneys from living donors is based on strict glomerular filtration rate (GFR) values, in the setting of the increasing proportion of older donors.
- Trial name
- DOVIMIR (NCT06047106)
- Testing
- multiparametric MRI, kidney graft biopsy, blood samples
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Addison Disease, Hypoaldosteronism
Adrenal Function After Living Kidney Donation
The success of kidney transplantation is hampered by the shortage of organs. One attractive strategy is the use of kidneys from living donors.
- Trial name
- NCT00251836
- Testing
- Laparoscopic hand-assisted donor nephrectomy
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Kidney Transplantation
Living Donation and Kidney Transplantation Information
The purpose of this study is to increase awareness and knowledge regarding the risks and benefits of kidney transplantation and living donation amongst patients seeking kidney transplantation and their family and friends in…
- Trial name
- KIDNEYTIME (NCT04285203)
- Testing
- Educational Video Intervention
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- State University of New York at Buffalo
Kidney Transplantation
Medical Economic Evaluation and of Quality of Life of the Kidney Living Donors.
The main objective of this multicentre study is to conduct the evaluation of cost-efficiency of various techniques of kidney taking with regard the quality of life of the kidney living donors.
- Trial name
- DOVIREIN (NCT02830568)
- Testing
- open donor nephrectomy, standard and hand-assisted laparoscopic donor nephrectomy, laparoscopic robotic-assisted nephrectomy
- Where
- 24 sites in France
- Volunteers
- 268 people
- Sponsor
- Central Hospital, Nancy, France
Chronic Kidney Diseases, Apolipoprotein L1
APOL1 Genetic Testing Program for Living Donors
Living donor (LD) kidney transplantation is the optimal treatment for patients with end-stage kidney disease (ESKD). However, LDs take on a higher risk of future ESKD themselves.
- Conditions
- Chronic Kidney Diseases, Apolipoprotein L1, Kidney Transplantation
- Trial name
- NCT04910867
- Testing
- Components of Genetic Counseling, APOL1 genetic testing, EHR integration
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- Northwestern University
Atelectasis, Postoperative, Pulmonary Complication
Evaluation of Perioperative Lung Ultrasound Scores (LUS) in Living Donor Nephrectomy Surgeries
Living donor nephrectomy surgeries can be performed in lateral position with laparoscopic technique which necessitates pneumoperitoneum. Considering the position and the pneumoperitoneum, lungs can be affected macroscopically.
- Trial name
- NCT05815888
- Testing
- Lung Ultrasound Score
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Living Kidney Donation
eHealth Usability in Living Kidney Donation
Several web portals for patients are available, but an assessment of their performance is scarce. This is of particular interest among candidates for kidney living donation.
- Trial name
- NCT04791670
- Testing
- survey study
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Postoperative Pain, Analgesics, Opioid
The Effects of TFPB on Opioid Consumption in Patients Undergoing HLDN
This study aims to evaluate whether a regional anesthesia technique called the transversalis fascia plane block (TFPB) can improve pain control after hand-assisted laparoscopic donor nephrectomy (HALDN), a minimally invasive…
- Conditions
- Postoperative Pain, Analgesics, Opioid, Pain Management, Anesthesia Regional
- Trial name
- NCT07396753
- Testing
- Ultrasound-guided transversalis fascia plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Koç University
Living Kidney Donation, Preoperative Anxiety
Preoperative Psychotherapy and Its Effects on Anxiety, Hemodynamics, and Pain in Living Kidney Donors
Chronic kidney failure is a condition in which the kidneys progressively lose their ability to filter waste, maintain fluid and electrolyte balance, and support essential physiological functions.
- Conditions
- Living Kidney Donation, Preoperative Anxiety, Postoperative Pain
- Trial name
- PREPSY-KD (NCT07261917)
- Testing
- Preoperative Psychiatric Consultation, No Intervention: Standard Preoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Living Kidney Donation, Hypertension
Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy
The goal of this observational study is to learn if PRAT thickness is a marker of visceral obesity and its influence on donors' kidney function and blood pressure in living kidney donors.
- Conditions
- Living Kidney Donation, Hypertension, Nephrectomy
- Trial name
- ProActive (NCT06886087)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chronic Pain, Living Kidney Donor
The Effect of Quadratus Lumborum (QL) Block on the Incidence of Chronic Neuropathic Pain After Retroperitoneal Laparoscopic Donor Nephrectomy: A Study on Neuroinflammation and Neurophysiology
To analyze the relationship of anterior subcostal quadratus lumborum (QL) block compared with control block on the incidence of chronic neuropathic pain at three months post-laparoscopic retroperitoneal living kidney donor.
- Conditions
- Chronic Pain, Living Kidney Donor, Quadratus Lumborum Block, Laparoscopic Donor Nephrectomy
- Trial name
- NCT07037992
- Testing
- injection of local anesthesia solution, Injection of normal saline
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Living-Kidney Donors
Dietary Interventions During Living Kidney Donations
Monocentre, non-randomized, non-blinded, open-label interventional study to identification of relevant changes in molecular biology in proteome, phosphoproteome, lipidome, epigenome and transcriptome in pretransplant kidney…
- Trial name
- DILKID (NCT05709600)
- Testing
- Fasting mimicking diet, Ketogenic diet, Dietary restriction of sulfur containing amino acids
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cologne
Nephrectomy,Kidney Donation
A Comparison of Kidney Function After Nephrectomy in Living Donors Under Sevoflurane and Desflurane Anesthesia
Living-donor kidney transplantation has been considered as the best treatment for patients with end-stage renal disease (ESRD). Kidney donation from living donors has been performed widely under their noble humanity and a belief…
- Trial name
- NCT01549990
- Testing
- Sevoflurane, desflurane
- Where
- South Korea
- Volunteers
- 236 people
- Sponsor
- Yonsei University
Kidney Transplant Candidates
Increasing Communication About Live Donor Kidney Transplant
This study will test the efficacy of a communication intervention intended to increase and improve kidney transplant candidates' communication about live donor kidney transplantation.
- Trial name
- NCT01855438
- Testing
- Living Donor Transplant Education
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Virginia Commonwealth University
End-stage Renal Disease
Network Interventions to Reduce Disparities in Living Kidney Donation
For this current phase of the larger project, the investigators will survey transplant candidates as well as the participants family and friends to understand the barriers to volunteering and evaluation.
- Trial name
- NCT05255757
- Testing
- Script Intervention, Search Intervention
- Where
- 2 sites in United States
- Volunteers
- 164 people
- Sponsor
- Penn State University
HIV Infections
Prospective Clinical Trial of HIV+ Living Donor Kidney Donation for HIV+ Recipients
Prospective Clinical Trial of HIV+ Living Donor Kidney Donation for HIV+ Recipients
- Trial name
- NCT03408106
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Johns Hopkins University
Kidney Failure, Surgery
Effect of Lost Wage Reimbursement to Kidney Donors on Living Donation Rates
The study is designed as a randomized controlled trial. The investigators hypothesize that kidney transplant recipient candidates whose donors are offered reimbursement of lost wages (treatment arm) will have a higher probability…
- Conditions
- Kidney Failure, Surgery, Renal Failure
- Trial name
- NCT03350269
- Testing
- Information provision
- Where
- 6 sites in United States
- Volunteers
- 1,310 people
- Sponsor
- Arbor Research Collaborative for Health
Chronic Kidney Disease
Culturally Sensitive Behavioral Interventions to Enhance Living Kidney Donation / Living Kidney Transplantation
Title: Culturally tailored behavioral interventions to enhance living kidney donation/living kidney transplantation Applicants: Johns Hopkins Medical Institutions, National Kidney Foundation of Maryland Principal Investigator…
- Trial name
- TALK (NCT00932334)
- Testing
- TALK PLUS, TALK Standard, Usual Care
- Volunteers
- 145 people
- Sponsor
- Johns Hopkins University
Pain, Postoperative, Donor Site Complication
Pain Management in Laparoscopic Living-donor Nephrectomy: The Impact of Erector Spinae Plane Block (ESPB) on Perioperative Period
Laparoscopic living donor nephrectomy (LLDN) is a safe procedure and rapid wound healing, affecting the quality of life. The physiology of postoperative pain after LLDN has been attributed to reasons such as tissue damage…
- Trial name
- NCT04867070
- Testing
- NAS score
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Akdeniz University