Clinical trials: Lipoma
Liposarcomas, Dedifferentiated, Liposarcoma - Well Differentiated
A Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma
The purpose of this study is to determine whether ribociclib are effective and safe in the treatment of progressive well/dedifferentiated liposarcoma (WDL/DDL).
- Conditions
- Liposarcomas, Dedifferentiated, Liposarcoma - Well Differentiated, Liposarcoma; Mixed Type, Soft-Tissue Sarcoma
- Trial name
- NCT03096912
- Testing
- Ribociclib
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Nevus, Seborrheic Keratosis (SK)
Optimizing the Timing for Facial Surgical Dressing Removal
What is this study about? You are being invited to participate in a clinical research study because you are scheduled to undergo a facial skin surgery for your health condition.
- Conditions
- Nevus, Seborrheic Keratosis (SK), Cyst, Lipoma
- Trial name
- NCT07441538
- Testing
- sterile gauze dressing
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lipoma
RFA for Superficial Lipomas
Lipomas are non-cancerous growths of fatty tissue that develop under the skin in approximately 1 in 1000 people, though this number may be higher.
- Trial name
- NCT06903208
- Testing
- STARMed VIVA Combo RF System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Columbia University
Soft Tissue Sarcoma, Lipoma
Incisional Negative Pressure Wound Therapy for Resection of Soft Tissue Tumors
This study is aimed to examine the value of incisional negative pressure therapy after resection of soft tissue tumors. Its a prospective randomized trial comparing incisional negative pressure to standard wound dressings.
- Conditions
- Soft Tissue Sarcoma, Lipoma, Tumor
- Trial name
- NCT03900078
- Testing
- Incisional negative pressure wound therapy, Wound dressing with adhesive tapes
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Ruhr University of Bochum
Lipoma
Association of Beta-2 Adrenergic Agonist and Corticosteroid Injection in the Treatment of Lipomas
The purpose of this study is to test whether injected medications will increase the amount of fat released by a fat cell. We will compare prednisolone (a synthetic cortisone) combined with isoproterenol (a drug given for asthma)…
- Trial name
- NCT00624416
- Testing
- Prednisolone synthetic cortisone and Isoproterenol together
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Tethered Spinal Cord, Including Thickened Filum, Lipomas, Myelomeningocele and Meningocele
Inflammatory Response in Children Suffering From Tethered Cord
Embryologic phenomenons that lead to dysraphisms are known, but pathophysiology remains questioned. It is supposed not to be a simple mechanistic dysfunction, and other biological phenomenons are implied in spinal cord damaging.
- Trial name
- TETHERIC (NCT07611058)
- Testing
- CSF sampling during surgery
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Lille
Dercum's Disease
A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With Dercum's Disease Lipomas
This Phase 2 study will be an open-label and randomized study to assess the efficacy and safety of CBL-514 in participants with Dercum's Disease lipomas.
- Trial name
- NCT05387733
- Testing
- 10 mg CBL-514 per injection, 15 mg CBL-514 per injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
Lipoma
Deoxycholic Acid Injection for the Treatment of Superficial Lipomas
The purpose of this research is to compare the safety and effectiveness of 4 different concentrations of deoxycholic acid injection against a placebo in the treatment of superficial lipomas.
- Trial name
- NCT00422188
- Testing
- Deoxycholic Acid Injection
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Kythera Biopharmaceuticals
Lipomas
Ultra-sounded Guided Regional Blockade for Lipoma Excision
There is limited information on using the ultrasonography for block placement concerning lipoma excision. A new type of regional blockade, performed under ultrasound, can ensure proper block placement with accurate local…
- Trial name
- NCT02753361
- Testing
- Ultrasound guidance
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Suez Canal University
Lipoma of Spinal Cord
Developing a Biomarker for Monitoring Clinical Outcomes in Children With Spinal Lipoma.
'Spinal lipoma' is a condition, present from before birth, in which fatty tissue (lipoma) is attached to the lower end of the spinal cord, tethering it within the vertebral canal.
- Trial name
- NCT02722681
- Testing
- Blood and urine sampling, Cerebrospinal fluid sampling
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Institute of Child Health
Vesico-Ureteral Reflux, Filum Terminale Lipoma
Effects of Parental Holding on Pain Response in Young Children During Cystometry
Cystometry is essential for diagnosis and treatment plans by identifying the causes of lower urinary tract symptoms and objectively evaluating bladder functions in diseases such as neurogenic bladder, voiding dysfunction, and…
- Trial name
- NCT05864131
- Testing
- Lying, Holding
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Yonsei University
Buccal Cavity Cancer, Labial Lipoma
Buccal Evaluation of Mobile Beach Workers
Tumors in the oral region occur more frequently in men over 40, but can affect people of both gender and all ages, even children.
- Trial name
- NCT04236700
- Testing
- Oral clinical exam
- Where
- 2 sites in Brazil
- Volunteers
- 300 people
- Sponsor
- Universidade Metropolitana de Santos
Lipoma
Double Blind Study to Evaluate the Efficacy of Collagenase Histolyticum in the Treatment of Lipoma
The purpose of this study is to determine whether collagenase is effective in reducing the surface area of a subcutaneous benign lipoma.
- Trial name
- NCT02249052
- Testing
- AA4500
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Gerut, Zachary, M.D.
Lipoma
Lipomas Treated With Subcutaneous Injections of Cooled or Warmed Sodium Chloride
Lipomas are benign tumors composed of mature adipose tissue. While harmless, these are the most common type of soft tissue growths with some patients developing numerous lipomas.
- Trial name
- NCT06820164
- Testing
- Cooled Sodium Chloride Injection, Warmed Sodium Chloride Injection
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Lipedema, Dercum's Disease
Insight Into Subcutaneous Adipose Tissue Disorders
The INSIGHT study aims to phenotype individuals with subcutaneous adipose tissue (SAT) disorders specifically lipedema and Dercum's disease with an aim to find a cure for the SAT in these disorders that is resistant to diet and…
- Conditions
- Lipedema, Dercum's Disease, Familial Multiple Lipomatosis, Madelung's Disease
- Trial name
- INSIGHT (NCT02838277)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Dercum's Disease Lipomas
RZL-012 for Dercum's Disease Lipomas
Thirty-eight (38) subjects will be included in the study. Subjects will be randomized in a ration of 1:1 to be treated with RZL-012 or placebo.
- Trial name
- NCT04229030
- Testing
- RZL-012, Vehicle
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Raziel Therapeutics Ltd.
Lipoma, Submental Fullness
Intralesional Ronkyla Plus Injection for the Treatment of Superficial Lipoma
This study aims to evaluate the safety, efficacy, and pharmacokinetics of Ronkyla Plus, a combinational drug that forms a hydrogel at the injection site, promising a better experience of lipolysis injection for the treatment of…
- Trial name
- NCT07237425
- Testing
- Ronkyla Plus, Kybella
- Where
- 3 sites in Taiwan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Glonova Pharma Co., Ltd
Spinal Cord Tumors
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment
In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue.
- Trial name
- NCT05957679
- Testing
- Magnetic Resonance Elastography, Assessment and Recording
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Lipoma
Evaluating the Efficacy and Safety of Embella (Deoxycholic Acid, Produced by Espad Pharmed Co.) Injection in the Management of Superficial Lipomas
Lipoma is a relatively common, slow-growing mesenchymal neoplasm originating from adipose tissue. Patients seek treatment for lipomas for various reasons, such as concerns about their growth and spread, aesthetic issues, or…
- Trial name
- NCT07014163
- Testing
- Embella (Deoxycholic acid, produced by Espad Pharmed Co.)
- Where
- 2 sites in Iran
- Volunteers
- 10 people
- Sponsor
- Espad Pharmed
Lipoma
A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma
The purpose of this research is to evaluate the safest and most effective dose of a Food and Drug Administration (FDA) approved drug (XIAFLEX) in the treatment of lipoma (fatty tumors of varying sizes that occur commonly in the…
- Trial name
- NCT01613313
- Testing
- Collagenase Clostridium Histolyticum
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Zachary Gerut