Clinical trials: Lipid Disorders and Lipid Measurement
Tear, Dry Eye Syndromes
Effect of ADDE on Tear Interferometry
Importance: Lipid layer thickness (LLT) reflects the lipid components of tear film, but is affected by the mucocutaneous components.
- Trial name
- NCT05456061
- Testing
- 3% diquafosol eyedrops, Silicone punctal plug insertion
- Where
- South Korea
- Volunteers
- 152 people
- Sponsor
- Yonsei University
Cardiovascular Diseases, Hyperlipidemias
The Mixed Meal Challenge Study
The purpose of this study is to assess sample collection conditions for various dietary challenges (fat, sugar, and mixed) and determine the optimal fasting and post-meal sample collection time points for future studies on a…
- Trial name
- NCT05087823
- Testing
- Lipid Challenge, Glucose Challenge, Mixed Meal Challenge
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Emory University
Cardiovascular Diseases
Lipid Challenge in Adults
Participants in this study will have one visit to the Emory University Hospital Clinical Research Unit. Participants will consume, over 5 minutes, a single standardized fat challenge (100 grams), using a commercially available…
- Trial name
- NCT03948295
- Testing
- Lipid Challenge
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Emory University
Obesity, Childhood, Obesity, Adolescent
PROBESITY-2: Synbiotics in Pediatric Obesity
The global obesity epidemic presents an unprecedented challenge to the public health worldwide. The factors associated with obesity are complex, and include health behaviours, such as eating habits and daily physical activity…
- Trial name
- PROBESITY-2 (NCT05162209)
- Testing
- Synbiotic
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Major Depressive Disorder, Bipolar Disorder
Naturalistic Study of Ketamine in the Treatment of Depression
This study aims to examine the effect of ketamine in decreasing the risk of suicide in patients with depression and its effectiveness as an antidepressant agent.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Bipolar Depression, Bipolar I Disorder
- Trial name
- NCT05249309
- Testing
- Ketamine
- Where
- 2 sites in Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Insulin Resistance, Oxidative Stress
Microencapsulated Fish Oil or Conjugated Linoleic Acid in Metabolic Syndrome
Our aim was to assess the effects of a hypocaloric diet, including diet fruit jelly with microencapsulated fish oil or conjugated linoleic acid or placebo, on anthropometry, body composition, insulin resistance and lipid profile…
- Conditions
- Insulin Resistance, Oxidative Stress, Lipid Profile, Blood Pressure
- Trial name
- NCT02183922
- Testing
- microencapsulated conjugated linoleic acid, microencapsulated fish oil, light fruit jam
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Type 2 Diabetes Mellitus
The Effect of Chlorella Supplementation on Patients With Type 2 Diabetes Mellitus
Diabetes is a chronic disease and the prevalence of diabetes mellitus is rapidly increasing as a result of population ageing, urbanization and associated lifestyle changes.
- Trial name
- NCT03625856
- Testing
- Chlorella Vulgaris
- Where
- Iran
- Volunteers
- 84 people
- Sponsor
- Dr. Behnood Abbasi
Mucopolysaccharidosis, Fabry Disease
Non-invasive Assessment of Intraocular Pressure in MPS by Use of the Ocular Response Analyzer.
The aim of the present study is to compare intraocular pressure (IOP) values assessed with Ocular Response Analyzer to the classical gold standard of IOP measurement, to Goldmann applanation tonometry by mucopolysacchyridosis…
- Trial name
- MPSORA (NCT01695161)
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Type 2 Diabetes Mellitus
Is There a Metabolic Effect of Cinnamon on HbA1c, Blood Pressure and Serum Lipids in Type 2 Diabetes Mellitus?
The aim of the study is to assess whether dietary supplementation of cinnamon (cinnamon cassia) has the potential to improve HbA1c, blood pressure and serum lipid measurements in patients with type 2 diabetes mellitus.
- Trial name
- cinnamon (NCT00846898)
- Testing
- cinnamon 2g per day for 12 weeks
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- Thames Valley University
Overweight, Obesity
Safety & Efficacy of Omega-3 Fish Oil in Overweight Children & Adolescents
Children with an excess in body weight, increase the risk of obesity-related co-morbidities and cardiovascular diseases. Childhood obesity may be due to diets laden with fat and lack of physical activity.
- Trial name
- NCT00447291
- Testing
- Supplement: Omega-3 Fish Oil, Multi-Disciplinary Nutrition & Exercise program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Heart Center
Metabolic Syndrome
The Effects of Nanomicelles Curcumin on Glycemic Control, Serum Lipid Profile ,Blood Pressure and Anthropometric Measurements in Patients With Metabolic Syndrome
Metabolic syndrome is a condition which is recognized by abdominal obesity, dyslipidemia, hyperglycemia, and hypertension. Curcumin has beneficial effects such as antioxidant and anti-inflammatory effects.
- Trial name
- NCT03534024
- Testing
- nanomicielle curcumin
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Nutrition and Food Technology Institute
Hypercholesterolemia, Dyslipidemia
Lipid Biomarker Study in Men With Dyslipidemia After Simvastatin Treatment (Study MK-0000-140)(COMPLETED)
The purpose of this study was to provide human lipidomics standards with simvastatin treatment that were to be used for comparison with similar preclinical studies.
- Trial name
- NCT00935259
- Testing
- Simvastatin
- Volunteers
- 31 people
- Sponsor
- Merck Sharp & Dohme LLC
Gaucher Disease Type 1
Comparison of BMD Measurement by DEXA to BeamMed Speed-of-Sound Measurement at Forearm in Patients With Gaucher Disease
The purpose of this study is to compare the accuracy and comparability and secondarily to assess the values achieved by measurement of the forearm BMD by DXA and SOS by BeamMed, relative to standard DXA evaluations at the FN and…
- Trial name
- NCT02067247
- Testing
- BeamMed Speed-of-Sound bone strength test at forearm
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Chronic Disease
Smart Watch, Heart Rate and So2 in Chronic Patients
Background: Apple watch validity to measure the heart rate (HR) and oxygen saturation (Spo2) in healthy subjects has been investigated, but its accuracy and validity for patients with chronic non-communicable diseases such as…
- Trial name
- NCT05271864
- Testing
- Apple Watch
- Where
- Saudi Arabia
- Volunteers
- 41 people
- Sponsor
- Umm Al-Qura University
Dry Eye
Comparative Assessment of Lipid Layer Thickness Measurements
This study compares ocular lipid layer thickness (LLT) measurements obtained from three commonly used clinical diagnostic devices to evaluate their agreement and consistency.
- Trial name
- NCT07579130
- Testing
- LipiView, Omnicad, Bruder Ocular Surface Analyzer
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana University
Metabolic Syndrome
Green Coffee Extract and Metabolic Syndrome
Metabolic syndrome (Mets) is an assemblage of risk factors which can increase the risk of developing type 2 diabetes mellitus and cardiovascular disease.
- Trial name
- NCT02764957
- Testing
- green coffee extract
- Where
- Iran
- Volunteers
- 43 people
- Sponsor
- National Nutrition and Food Technology Institute
High Blood Cholesterol Level
The Effect of Plant Sterol Supplement on Blood Cholesterol
The purpose of this study is to determine whether supplement of plant sterol could lower blood cholesterol.
- Trial name
- NCT00485095
- Testing
- Intake of plant sterols
- Where
- 2 sites in Norway
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Obesity
Effects of Spirulina Supplementation on Overweight or Obese Adults
In this double-blind Randomized Controlled Clinical Trial investigators are going to study the effects of Spirulina supplementation on anthropometric measurements, lipid profile, appetite, liver enzymes, inflammatory and glycemic…
- Trial name
- NCT02993627
- Testing
- Spirulina, diet therapy
- Where
- Iran
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
HIV, HIV-Infections
The Visceral Adiposity Measurement and Observation Study
The Visceral Adiposity Measurement and Observation Study
- Conditions
- HIV, HIV-Infections, HIV-1-infection, HIV I Infection
- Trial name
- VAMOS (NCT05383456)
- Testing
- Diagnostic Test, HIV Anti-retroviral Background Therapy
- Where
- 8 sites in United States
- Volunteers
- 196 people
- Sponsor
- Theratechnologies
Generalised Lipodystrophy, Partial Lipodystrophy
MEASuRE: Metreleptin Effectiveness And Safety Registry
The study is a post-authorization, prospective, voluntary registry of patients treated with commercial metreleptin including, but not limited to, patients in the US and EEA.
- Trial name
- MEASuRE (NCT02325674)
- Testing
- Metreleptin
- Where
- 28 sites in United States, France and 3 more
- Volunteers
- 100 people
- Sponsor
- Chiesi Farmaceutici S.p.A.