Clinical trials: Lipedema
Lower-Limb Lipedema, Lipedema
"Effect of Endermologie-Assisted Physiotherapy on Edema, Pain, and Functional Recovery After Liposuction for Lower-Limb Lipedema"
Lipedema is a chronic condition that mainly affects women and causes abnormal fat accumulation, pain, heaviness, tenderness, swelling, and difficulty with movement, especially in the lower limbs.
- Trial name
- NCT07618065
- Testing
- Endermologie-Assisted Physiotherapy, Standard Postoperative Physiotherapy
- Where
- 2 sites in Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Lipedema
Telerehabilitation-Supported Exercise in Women With Lipedema
This prospective, single-blind, randomized controlled trial aims to evaluate the effectiveness of a telerehabilitation-supported exercise program in women with lipedema.
- Trial name
- NCT07885241
- Testing
- Telerehabilitation-Supported Exercise, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University
Lipedema, Obesity
Comparison of Segmental Body Composition Characteristics in Lipedema and Obesity
The aim of this study is to compare the total and regional body composition characteristics of women with lipedema and women without lipedema who are matched for age and body mass index, as determined by the TANITA MC-580…
- Conditions
- Lipedema, Obesity, Body Mass Index, Bioelectrical Impedance Analysis
- Trial name
- NCT07878299
- Testing
- Bioelectrical Impedance Analysis, Numeric Rating Scale, Lower Extremity Functional Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Aerobic Exercise, Lipedema
Comparison of Different Exercise Protocols for Diagnosed With Lipedema
This study was designed to compare the effects of high-intensity interval training and moderate-intensity continuous training on functional capacity, muscle strength, and quality of life in patients with lipedema, and to…
- Trial name
- NCT07873541
- Testing
- High-Intensity Interval Aerobic Exercise Group, Moderate Intensity Continuous Group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hitit University
Lipedema, Obesity & Overweight
Ultrasonographic Evaluation and Pedobarographic Correlation of Lower Extremity Muscles in Lipedema Patients
The primary aim of this study is to evaluate the lower extremity muscle structure, lower extremity alignment, and foot posture in lipedema; secondly, to reveal the chain relationship and biomechanical problems that may be…
- Trial name
- PODUSG (NCT07724483)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lipedema
Transcutaneous Auricular Vagus Nerve Stimulation-Enriched Rehabilitation in Individuals With Lipedema
Lipedema is a chronic inflammatory disorder of adipose tissue that predominantly affects women and is associated with estrogen-mediated mechanisms.
- Trial name
- LipoVNS (NCT07857499)
- Testing
- Active taVNS, Aerobic Exercise, Complex Decongestive Therapy (CDT)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Lipedema
The Effect of Mediterranean Diet on Pain Level and Biochemical Parameters in Women With Lipedema
Objective: To evaluate the effects of a 3-month Mediterranean diet-based intervention on anthropometric and metabolic outcomes, pain and central sensitisation-related symptoms in women with lipedema.
- Trial name
- NCT07853833
- Testing
- Mediterranean Diet-Based Nutritional Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Baskent University
Lipedema
Pain, Central Sensitization, and Misophonia in Lipedema
Lipedema is a chronic condition that predominantly affects women and is characterized by disproportionate, usually symmetrical accumulation of subcutaneous fat, particularly in the hips and legs.
- Trial name
- NCT07849634
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Assessment, Lipedema
Physical Therapy in Lipedema Surgery
The goal of this observational study or clinical trial is to know evaluate the effects of a modified Complete Decongestive Therapy protocol using the Godoy Method in the postoperative period following lipedema surgery.
- Conditions
- Assessment, Lipedema, Vascular Diseases, Dermatologic Complication
- Trial name
- NCT05966779
- Testing
- modified CDT physical therapy protocol, based on Godoy's Method
- Where
- Spain
- Volunteers
- 293 people
- Sponsor
- University of Alcala
Dercum's Disease
A Study to Evaluate the Efficacy and Safety of CBL-514 Compared to Placebo in Participants With Dercum's Disease Lipomas
This is a single-blind, placebo-controlled, randomized phase 2 study to evaluate the efficacy and safety of CBL-514 injections in participants with Dercum's Disease lipomas.
- Trial name
- NCT06303570
- Testing
- CBL-514 injection, 0.9% Sodium chloride
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
Lipedema
Validity and Reliability of the Turkish Duke Activity Status Index in Women With Lipedema
This study aims to evaluate the validity and reliability of the Turkish version of the Duke Activity Status Index (DASI) in women with lipedema.
- Trial name
- DASI-LIP (NCT07803913)
- Testing
- Duke Activity Status Index (DASI)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Lipedema
Manual and Self-Lymphatic Drainage Combined With Exercise in Women With Lipedema
This randomized controlled study aims to compare the effects of two physiotherapy approaches in women with lipedema. Participants will be assigned to either manual lymphatic drainage combined with supervised aerobic exercise or…
- Trial name
- LipoMOVE (NCT07803926)
- Testing
- Manual Lymphatic Drainage, Aerobic Exercise, Self-Lymphatic Drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Merve SEVINC GUNDUZ
Lipedema, Hypermobility, Joint
Joint Hypermobility and Associated Factors in Patients With Lipedema
The aim of this observational study is to determine the prevalence of joint hypermobility in female patients with lipedema compared to healthy volunteers.
- Trial name
- LIP-HYP (NCT07808242)
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Lipedema, Sarcopenia
Sarcopenia and Related Factors in Lipedema
Lipedema is a common disease of subcutaneous adipose tissue. The most common complaint of patients with swelling in the affected extremity is pain.
- Conditions
- Lipedema, Sarcopenia, Musculoskeletal Diseases
- Trial name
- NCT05739279
- Testing
- STAR-Sonographic Thigh Adjustment Ratio, Hand Grip Strength, Chair Stand Test
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Lipedema, Inflamation
Investigation of Systemic Inflammation Markers in Lipedema
The aim of this study is to evaluate systemic inflammation in individuals with lipedema using hematological and biochemical inflammation indices and to examine the relationship between these indices and clinical findings.
- Conditions
- Lipedema, Inflamation, Inflammation Biomarkers, Obesity & Overweight
- Trial name
- NCT07787234
- Testing
- Clinical parameters, Laboratory parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Lipedema, Magnesium
Serum Magnesium Levels in Patients Diagnosed With Lipedema
Female patients diagnosed with lipedema will be divided into two groups based on their Pittsburgh Sleep Quality Index (PSQI) scores: PSQI ≤ 5 and PSQI > 5.
- Trial name
- NCT07779577
- Testing
- Magnesium
- Volunteers
- 128 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lipedema, Osteoporosis
The Relationship Between Lipedema and Osteoporosis
The purpose of this study is to evaluate the relationship between lipedema and osteoporosis and to examine factors that may be associated with osteoporosis in individuals with lipedema.
- Trial name
- NCT07779603
- Testing
- DXA
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lipedema
Aquatic Versus Land-Based Exercise in Women With Lipedema
To evaluate optimal workout environments, a 12-week study assigned women with moderate-to-severe lipedema to three distinct protocols: supervised pool workouts, equivalent land-based training, or basic standard monitoring.
- Trial name
- NCT07756463
- Testing
- aquatic therapy, land- based exercise, usual care
- Volunteers
- 60 people
- Sponsor
- Cairo University
Lipedema
Validity and Reliability of the 2-Minute Step Test in Patients With Lipedema
Lipedema is a chronic, progressive adipose tissue disorder that predominantly affects women and is characterized by symmetric, disproportionate subcutaneous fat accumulation in the lower extremities, pain, tenderness, and easy…
- Trial name
- NCT07752017
- Volunteers
- 55 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lipedema
Efficacy of Complex Decongestive Therapy, Exercise and Diet in Women With Lipedema
The purpose of this study is to compare the effectiveness of standard physical therapy methods (Complex Decongestive Therapy, Pneumatic Compression, and Exercise) combined with two different nutritional approaches (personalized…
- Trial name
- NCT07667270
- Testing
- Anti-inflammatory Diet and Physical Therapy, Standard Diet and Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Balikesir University