Clinical trials: Linked Color Imaging
Gastritis, Helicobacter Pylori Associated Gastritis
Linked Color Imaging to Differentiate H. Pylori Associated Gastritis and Gastric Atrophy
H. pylori infection plays a very important role in gastric carcinogenesis, progressing from chronic gastritis through atrophic gastritis, intestinal metaplasia, dysplasia and finally cancer. It is difficult to diagnose H.
- Conditions
- Gastritis, Helicobacter Pylori Associated Gastritis, Atrophic Gastritis
- Trial name
- NCT02724280
- Testing
- WLE and then LCI, LCI and then WLE
- Where
- China
- Volunteers
- 253 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Ulcerative Colitis (UC)
The Fecal Immunoassay Occult Blood Test Combined With Calprotectin Sequential Linkage Imaging Endoscopy Screening Strategy for Monitoring Tumor Changes Associated With Long-duration Ulcerative Colitis
Ulcerative colitis (UC) is a chronic inflammatory bowel disease associated with an increased risk of colorectal cancer, known as UC-associated neoplasia (UCAN).
- Trial name
- DETECT-UCAN (NCT07742410)
- Volunteers
- 250 people
- Sponsor
- Qilu Hospital of Shandong University
Colonic Polyps, Adenomatous Polyps
Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate
Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate, but considering the long…
- Conditions
- Colonic Polyps, Adenomatous Polyps, Adenoma Detection Rate, Chromoendoscopy
- Trial name
- NCT06961149
- Testing
- Chromoendoscopy with indigo carmine solution spray, Linked-color imaging endoscopy
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Shandong University
Small Colon Polyps, Linked Color Imagimg
The Characterization of Small and Diminutive Colonic Polyps in LCI
Colorectal cancer is a maior cause of morbidity and mortality worldwide.Colonoscopy and removal of all adenomas is the most efficient method to prevent colorectal cancer.The most colorectal polyps detected are small(<10mm) and…
- Conditions
- Small Colon Polyps, Linked Color Imagimg, Diminutive Colon Polyps
- Trial name
- NCT03351257
- Testing
- observation of surface patterns and colors of polyps
- Where
- 2 sites in China
- Volunteers
- 300 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Helicobacter Pylori Infection
Diagnosis Ability of Linked Color Imaging for Helicobacter Pylori Infection Compared With White Light Imaging
There are lack of endoscopic criteria for diagnosing Helicobacter pylori (H. pylori) infection by conventional white light imaging (WLI).
- Trial name
- NCT03011437
- Testing
- Esophagogastroduodenoscopy
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kashgar 1st People's Hospital
Colon Adenoma, Colonic Polyp
Linked Color Imaging (LCI) for Colorectal Adenoma Detection
Linked color imaging (LCI) is newly developed image-enhancing endoscopy technology that differentiates the red color spectrum more effectively than white light imaging thanks to its optimal pre-process composition of light…
- Trial name
- NCT03690297
- Testing
- Linked Color Imaging
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Valduce Hospital
CAG - Chronic Atrophic Gastritis, EGC - Early Gastric Cancer
LCI in Chronic Atrophic Gastritis and Early Gastric Cancer
Color change is a useful marker for the endoscopic identification of chronic atrophic gastritis (CAG) and gastric cancer (GC). Several histopathological studies have suggested a correlation between certain gastrointestinal…
- Trial name
- NCT06152263
- Testing
- Compare color information and mucosal microvascular density
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Polyp of Colon
Linked Color Imaging Versus White Light Endoscopy for the Evaluation of Scars of Non-pedunculated Polyps. LCI Scar Study.
Careful inspection and evaluation of the post-polipectomy scars of polyps greater than 20 mm looking for residual polyp is mandatory. LCI has demonstrated to improve polyp and adenoma detection rate in previous studies.
- Trial name
- LCIScar (NCT04899700)
- Testing
- Linked Color Imaging, White light endoscopy
- Where
- 2 sites in Spain
- Volunteers
- 173 people
- Sponsor
- Hospital Clinic of Barcelona
Colorectal Polyp, Linked Color Imaging
Computer-assisted Diagnosis System Based on Linked Colour Imaging
Linked color imaging (LCI)，a new endoscopy modality, creates clear and bright images by using short wavelength narrow band laser light. LCI can make red area appear redder and white areas appear whiter.
- Conditions
- Colorectal Polyp, Linked Color Imaging, Computer-aided Diagnosis
- Trial name
- NCT03359343
- Where
- 2 sites in China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Early Gastric Cancer, Barrett Esophagus
Linked Color Imaging vs White Light Imaging for Detection of Gastric Cancer Precursors
This study aims to examine the use of Linked Color Imaging in detection of gastric cancer precursors, as well as oesophageal and duodenal lesions.
- Trial name
- NCT03990025
- Testing
- Linked Color Imaging, White Light Imaging
- Where
- 2 sites in Singapore
- Volunteers
- 90 people
- Sponsor
- Changi General Hospital
Gastroesophageal Reflux Disease, Minimal Change Disease
Diagnostic Value of Linked Color Imaging for Minimal Change Esophagitis in Nonerosive Reflux Esophagitis and GERD
Linked color imaging(LCI),a new system for endoscopy modality,creates clear and bright endoscopic images by using short-wavelength narrow-band laser light combined with white laser light on the basis of magnifying blue laser…
- Conditions
- Gastroesophageal Reflux Disease, Minimal Change Disease, Non-Reflux Esophagitis
- Trial name
- NCT03068572
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Colonic Polyp
Linked-color Imaging for the Detection of Colorectal Flat Lesions
Linked color imaging (LCI) was recently developed and uses a laser endoscopic system (Fujifilm Co, Tokyo, Japan) that acquires images by simultaneously using narrow-band short-wavelength light and white-light (WL) in an…
- Trial name
- NCT03272945
- Testing
- Linked-color imaging
- Where
- Japan
- Volunteers
- 400 people
- Sponsor
- Showa Inan General Hospital
Ulcerative Colitis
Linked Color Imaging vs. White Light for Colorectal Dysplasia in Ulcerative Colitis
The purpose of the study is to determine whether a new colonoscopic viewing technique called Linked color imaging(LCI) helps endoscopists detect more dysplasia lesions in ulcerative colitis patients than conventional colonoscopy…
- Trial name
- NCT02772406
- Testing
- Linked Color Imaging, white light imaging
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Gastric Disease
Linked Color Imaging Based CMV Diagnosis for Gastric Mucosal Lesions
The newly developed linked color imaging (LCI) system (FUJIFILM Co.) creates clear and bright endoscopic images by using short-wavelength narrow-band laser light combined with white laser light on the basis of BLI technology.
- Trial name
- NCT03092414
- Testing
- WLE and then LCI, LCI and then WLE
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Adenoma Colon Polyp
LCI (Linked Color Imaging) for Adenoma Detection in the Right Colon
Although colonoscopy with polypectomy can prevent up to 80% of colorectal cancers, a significant adenoma miss rate still exists, particularly in the right colon.
- Trial name
- NCT03279783
- Testing
- LCI (Linked color imaging)
- Where
- Italy
- Volunteers
- 752 people
- Sponsor
- Valduce Hospital
Adenoma Colon, Colon Polyp
COmparison of White Light and Linked COlor Imaging for Detection of RIght COlon Polyps
Comparison of the number of adenomas missed by the first exploration of the right colon by LCI (linked color imaging) or by white light during a colonoscopy, according to the order of randomization.
- Conditions
- Adenoma Colon, Colon Polyp, Colonoscopy
- Trial name
- COCORICO (NCT04112563)
- Testing
- exploration in white light (WLI), Exploration in LCI
- Where
- France
- Volunteers
- 686 people
- Sponsor
- Société Française d'Endoscopie Digestive
Colorectal Adenoma, Colorectal Adenomatous Polyp
Analysis of New Endoscopic Features and Variable Stiffness in Colonoscopy: Prospective Randomised Trial
The aim of the present study is to develop and evaluate a computer-based methods for automated and improved detection and classification of different colorectal lesions, especially polyps.
- Trial name
- ELUFIBLI (NCT03234725)
- Where
- Hungary
- Volunteers
- 1,000 people
- Sponsor
- Bács-Kiskun County Teaching Hospital
Early Gastric Cancer
Application of Linked Color Imaging（LCI） in Diagnosis of Early Gastric Cancer(EGC)
the purpose of this study is to evaluate application value of LCI in the diagnosis of early gastric cancer.
- Trial name
- NCT03661671
- Testing
- LCI+white light
- Where
- China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Sessile Colonic Polyp, Serrated Lesion
Computer-Aided Water Exchange Colonoscopy With and Without Linked-Color Imaging for Detection of Clinically Significant Serrated Lesions
The goal of this clinical trial is to compare the detection rate of clinically significant serrated lesions (CSSL) in participants undergoing water exchange (WE) colonoscopy with artificial intelligence (AI)-based computer-aided…
- Conditions
- Sessile Colonic Polyp, Serrated Lesion, Sessile Serrated Lesion, Colon Adenomas
- Trial name
- NCT07127471
- Testing
- Water exchange with AI-assisted detection, Water exchange with AI-assisted detection and LCI
- Where
- 4 sites in Canada, Italy and 2 more
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- Evergreen General Hospital, Taiwan
Lynch Syndrome, Colonoscopy
Linked Color Imaging Versus High-definition White Light Endoscopy for the Detection of Polyps in Patients With Lynch Syndrome (LCI-LYNCH)
The aim of the present study is to compare polyp detection rates of LCI with high-definition white light endoscopy (HD-WLE) in patients with Lynch syndrome in a parallel, international, multicenter, randomized controlled…
- Trial name
- NCT03344289
- Testing
- Colonoscopy
- Where
- Netherlands
- Volunteers
- 357 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)