Clinical trials: Limb Edema
Total Knee Arthroplasty, Edema
The Effects of Manual Lymphatic Drainage and Kinesiotaping on Lower Extremity Edema
Significant trauma and muscular tightness often result during Total Knee Arthroplasty (TKA) surgery and thus act to restrict tissue fluid movement resulting with lower extremity edema.
- Conditions
- Total Knee Arthroplasty, Edema, Exercise
- Trial name
- NCT04164927
- Testing
- Manual Lymphatic Drainage, Kinesio Taping, Control
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Lymphedema, Lower Limb, Lymphedema
Detecting the Undetected: Heart Failure Screening at the Lymphoedema Point of Care
Heart failure affects more people than the four most common cancers combined. When identified early, management is more straightforward, preventing complications, hospitalisations, and fatalities.
- Conditions
- Lymphedema, Lower Limb, Lymphedema, Heart Failure, Heart Failure (for Example, Fluid Overload)
- Trial name
- NCT07498868
- Where
- United Kingdom
- Volunteers
- 618 people
- Sponsor
- Swansea Bay University Health Board
Edema, Chronic Venous Insufficiency
Validation of a New Method of Limb Volumetry
Volumetry is essential for the diagnosis and follow-up of patients with limb edema. The objective of this project is the validation of real-time reconstruction and calculation of limb volume using a 3D laser scanner.
- Conditions
- Edema, Chronic Venous Insufficiency, Lymphedema
- Trial name
- NCT01574911
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Edema
Oedematous Lower Limb Subcutaneous Drainage in Palliative Care
Background : Edema of lower extremities is a concern ranging from 19 % to 60% of palliative cancer patients. Lymphedema decreases mobility, induces pain, impacts daily activities, esthetic and behavior.
- Trial name
- DSOPAL (NCT02473744)
- Testing
- subcutaneous drainage
- Where
- 7 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Limoges
Healthy Subject
Effect of Pneumatic Tourniquet on Arm Swelling After Lymph Node Removal
The purpose of the proposed study is to evaluate the acute impact of swelling caused by low-pressure tourniquet use in the setting of ipsilateral prior axillary lymph node dissection and the change in swelling reduction following…
- Trial name
- NCT03584100
- Testing
- Tourniquet 8000
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Stanford University
Heart Failure
HF-TRACK: A UK RCT of an Passive Heart Failure Monitoring and Tracking Device
The objective of our research is to evaluate the effectiveness of an innovative medical device designed to measure foot and lower leg sizes in detecting early indications of deteriorating heart failure.
- Trial name
- HF-TRACK (NCT06334822)
- Testing
- Heartfelt Device installed, Standard care, Questionnaires
- Where
- 11 sites in United Kingdom
- Volunteers
- 186 people
- Sponsor
- Heartfelt Technologies
Chronic Lower Limb Edema With Unclear Etiology
A Large Series of Clinical and Imaging Investigation to Patients With Chronic Lower Limb Edema With Unclear Etiology
Patients with chronic lower limb edema commonly suffered from extremities edema, pain, varicosities, venous stasis changes, and deep venous thrombosis.
- Trial name
- NCT01208623
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Taipei Medical University WanFang Hospital
Oedema
Does NMES Help Relieve Lower Limb Oedema and Improve Joint Mobility and Skin Tissue Oxygenation Levels?
Neuromuscular Electrical Stimulation (NMES) will be facilitated through the use of a stimulator, with the patient in a semi recumbent position, using UltraStim electrodes.
- Trial name
- NCT01936155
- Testing
- Custom-built, two-channel stimulator
- Where
- Ireland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Breast Cancer Lymphedema
Effect of the Axillary Lymphatic /Vein Reflux Ratio on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
The purpose of this study is to compare the difference in the incidence of upper limb edema and dysfunction between the Preponderant lymphatic reflux group (high ratio of axillary lymphatic reflux to axillary vein reflux) and the…
- Trial name
- PLEDGE-R (NCT05246592)
- Testing
- Branches Sparing, None Branches Sparing
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Xiangyun Zong
Limb Volume, Measuring Edema
Measuring Volume Using a 3D Scanner and iPad to Grade the Swelling of Legs
We used a new and easy-to-measure iPad 3D scanner to measure swelling in lower limbs because current technology is not easily available or affordable.
- Trial name
- NCT06944041
- Testing
- STO3 sensor (Structure Inc., Boulder, CO)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The RANE Center for Venous and Lymphatic Diseases at St. Dominic's Hospital
Pregnancy Complications, Edema Leg
Efficacy of Percussion Massage Therapy Applied to the Lower Extremity on Pain, Edema in Pregnant Women
This study aim is to examine the effect of percussion massage therapy applied to lower extremity on pain, edema, fatigue and quality of life in pregnant women.
- Conditions
- Pregnancy Complications, Edema Leg, Physiotherapy
- Trial name
- NCT06338254
- Testing
- percussion massage therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Limb Salvage
Limb Salvage Post Venous Injury:Case Series
The venous injury diagnosis depends on history of trauma with symptoms and signs suggestive of venous injuries and color flow duplex study is of increasing value as a screen for detection of an occult venous injuries.
- Trial name
- NCT05223283
- Volunteers
- 75 people
- Sponsor
- Jabir Ibn Hayyan Medical University
Lipedema
Effects of Exercise in Patients with Lipedema
Lipedema is a chronic progressive disease characterized by symmetrical, disproportionate swelling of subcutaneous adipose tissue, which is common in women and mostly seen in the lower extremities and to a lesser extent in the…
- Trial name
- NCT06811961
- Testing
- Exercise, Physical activity
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ilke Keser
Breast Cancer Lymphedema
Effect of ALND With Vein Branches Reservation on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
The purpose of this study is to compare the effects of axillary lymph node dissection with or without axillary vein branches reservation on the affected upper limb edema and dysfunction in breast cancer patients, and to explore…
- Trial name
- PLEDGE-Surgery (NCT05120180)
- Testing
- axillary lymph node dissection with vein branches reservation, axillary lymph node dissection without vein branches reservation
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Xiangyun Zong
Heart Failure; With Decompensation, Lower Extremity Edema
Above-Knee-High Application of Lower Limb Compression and Its Impact on Clinical Outcome in Patients Hospitalized With Heart Failure Exacerbation.
Heart failure (HF) remains one of the most common causes of hospitalization with high morbidity and mortality, and its worldwide prevalence is increasing.
- Conditions
- Heart Failure; With Decompensation, Lower Extremity Edema, Heart Failure，Congestive
- Trial name
- A-KHALIFE (NCT05467735)
- Testing
- Application of compression to bilateral lower extremities of patients using appropriately-sized elastic compression stockings.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Stroke
Robot-assisted Rehabilitation of Hand by Paralysis of the Upper Limb After Stroke
The investigators evaluate the effectiveness of the application of continuous passive motion device for hand rehabilitation in two classes of patients: with a residual active motion and without a residual active motion.
- Trial name
- NCT01936298
- Testing
- A-ROM Continuous Passive Rehabilitation, P-ROM Continuous Passive Rehabilitation
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Chiara Mulé
Leg Injuries, Fracture
Soft Part Management for Surgical Fractures of the Lower Limb
The assessment consists in comparing corticoids injection versus placebo in surgery of lower limb fractures The aim of study is to assess (state cutaneous, efficacy, safety) corticoids injection on a prospective, randomized…
- Conditions
- Leg Injuries, Fracture, Edema
- Trial name
- ICOMI (NCT03915223)
- Testing
- leg fracture
- Where
- France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Clermont-Ferrand
Lymphedema, Edema
Surgical Evaluation for Upper Extremity Lymphedema (BioBridge)
To investigate whether the addition of Fibralign's BioBridge® Collagen Matrix (BioBridge) devices to the standard surgery for vascularized lymph node transfer will improve the outcome of surgical treatment in lymphedema of the…
- Trial name
- NCT05695924
- Testing
- BioBridge® Collagen Matrix, Vascularized Lymph Node Transfer (VLNT)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Fibralign Corporation
Hand Injuries and Disorders, Upper Extremity Problem
Pain, Range of Motion, Edema, Sensibility, Strength (PRESS) & Self-reported Function Create a Comprehensive Score
The aim of this study is to examine the development of a conceptual framework and provide evidence for reliability of a comprehensive hand therapy evaluation score.
- Trial name
- PRESS (NCT06155617)
- Testing
- Upper Extremity Rehabilitation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Howard University
Chronic Edema, Lymphedema
Boosted Compression for Lower Limb Chronic Edema
Patients: Patients targeted in this proposal comprise individuals afflicted by chronic edema/lymphedema of the lower limbs. Intervention: The intervention entails the incorporation of boosted compression alongside standard care…
- Trial name
- BECOME (NCT07708662)
- Testing
- Conservative edema treatment (complex decongestive therapy), Conservative edema treatment with boosted compression therapy
- Where
- 4 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- Universiteit Antwerpen