Clinical trials: Levobupivacaine
Hysterectomy, Laparoscopic Surgery
Transversus Abdominis Plane Block for Laparoscopic Hysterectomy
Purpose To evaluate whether adding a transversus abdominis plane block in patients undergoing elective laparoscopic hysterectomy reduces Patient-controlled analgesia (PCA) morphine requirements during the first 24 hours…
- Trial name
- NCT01552148
- Testing
- USguided bilateral TAP block, Morphine Patient Controlled Analgesia
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Istituti Ospitalieri di Cremona
Patients Undergoing Lower Limb Surgery
Comparative Study of the Effects of Two Local Anesthetics Administered Intrathecally: 0.5% Levobupivacaine and Ropivacaine 0.5%
This is a Biomedical Research, prospective, randomized, double blind, controlled monocentric, phase IV comparison of the effects of two local anesthetics intrathecally: 0.5% levobupivacaine and ropivacaine 0.5%.
- Trial name
- ROPI-LEVO (NCT01935596)
- Testing
- ropivacaïne, lévobupivacaïne
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
164 Boys for Hypospadias Surgery Under General Anesthesia With Caudal Block
Caudal Dexmedetomidine Analgesia in Pediatrics .
Dexmedetomidine (DEXM) is a highly selective α2-adrenoceptor agonist that has been used increasingly in pediatric anesthesia. This prospective double blinded randomized comparative study is designed to evaluate the analgesic…
- Trial name
- NCT03791879
- Testing
- Caudal dexamedatomidine analgesia
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Musculoskeletal Diseases or Conditions
Minimum Effective Local Anesthetic Volume for Ultrasound Guided Superior Trunk Block
The objective of this study is to identify the minimum effective dosage of a commonly used local anaesthetic drug "levobupivacaine" required to produce an effective ultrasound guided (USG) superior trunk block (STB) in at least…
- Trial name
- NCT04941664
- Testing
- 0.5% levobupivacaine
- Where
- Hong Kong
- Volunteers
- 25 people
- Sponsor
- Chinese University of Hong Kong
Diaphragmatic Paralysis, Brachial Plexus Block
Diaphragmatic Paralysis Comparison Between Local Anesthetic Volumen Doses After Interscalene Block
Arthroscopic shoulder surgery involves dynamic and severe postoperative pain. Interscalene brachial plexus block (IBPB) provides adequate analgesia but the spread of local anaesthetics administered causes a phrenic nerve block…
- Trial name
- REDOLEV-2019 (NCT04385966)
- Testing
- Interscalene brachial plexus block, Levobupivacaine Hydrochloride 2.5 MG/ML
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Spermatic Cord Block
Addition of Neostigmine to Levobupivacaine
Using the spermatic cord block has been of great advantage, as it has been cost saving, efficient technique whether used inon its own or combination with a sedative or .
- Trial name
- NCT04492319
- Testing
- Control Test, Neostigmine
- Where
- Egypt
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia, Regional
Comparison of an Interscalene Nerve Block With or Without Stellate Ganglion Block for Shoulder Surgery
This study describes the difference of analgesic effect of levobupivacaine 0.5% administered through an interscalene nerve block with or without a stellate ganglion block.
- Trial name
- NCT02879916
- Testing
- Levobupivacaine, NaCl 0.9%
- Volunteers
- 30 people
- Sponsor
- University Hospital, Antwerp
Pain, Postoperative
Intraperitoneal Atomization of Levobupivacaine During Gynaecological Laparoscopic Procedures ; Impact on Pain, Opioid Use and Length of Recovery Room Stay (IPLA).
In this study, we will compare 3 treatments. The first group of patients will receive the standard treatment (paracetamol, diclofenac and an opioid if necessary) with infiltration of the portal sites with the local anesthetic …
- Trial name
- IPLA (NCT01886352)
- Testing
- Standard Injection of Levobupivacaine in portal sites., Additional injection of 0,5% levobupivacaine., Intraperitoneal atomization of levobupivacaine.
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- University Hospital, Ghent
Arm Injuries, Anesthesia
Ultrasound-guided Supraclavicular Brachial Plexus Block in Elderly
The aim of this study is to determine the minimum effective volume of local anesthetic (50:50 mixture of 0.5% levobupivacaine and 2% lidocaine) required to produce an effective US-SCB for surgical anesthesia in 50% of patients…
- Trial name
- US-SCB (NCT01467596)
- Testing
- Elderly population, Middle aged population
- Where
- 2 sites in Croatia
- Volunteers
- 44 people
- Sponsor
- Šarić, Jadranka Pavičić, M.D.
General Anesthesia
Effect of Thoracic Epidural Analgesia on Intravenous Closed-Loop Anesthesia
The association of general anesthesia and of thoracic epidural anesthesia is used in thoracic surgery with a demonstrated benefit on the risk of postoperative respiratory complications.
- Trial name
- Drone-APDT (NCT00627081)
- Testing
- remifentanil
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hopital Foch
Normal Pregnancy
Comparative Affect of a Continuous Epidural Infusion of Clonidine During Labour. Prospective Double Blind Randomized Trial
Addition of clonidine to an epidural mixture of local anaesthetic and morphine improves analgesia and reduces the frequency of motor blockade during epidural analgesia.
- Trial name
- NCT00437996
- Testing
- Clonidine, Levobupivacaine, Sufentanil
- Where
- 2 sites in France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pain
Analgesic Effect of Levobupivacaine in Breast Augmentation
The purpose of this study is to determine whether levobupivacaine is effective in the acute postoperative pain treatment in periprosthetic breast augmentation
- Trial name
- NCT02465008
- Testing
- Levobupivacaine
- Volunteers
- 66 people
- Sponsor
- General University Hospital of Valencia
Postoperative Analgesia, Hand Strength
Long-term Outcomes of Breast Cancer Patients After Wound Infiltration Analgesia
In the study that was conducted from 05.01.2009 - 31.12.2012. 120 patients were examined. By drawing random numbers, the patients were randomized into 3 groups for postoperative analgesia: 1. Diclofenac 2 mg/kg/day - control, 2.
- Conditions
- Postoperative Analgesia, Hand Strength, Health Related Quality of Life, Chronic Shoulder Pain
- Trial name
- NCT05829707
- Testing
- Diclofenac Sodium, Levobupivacaine bolus analgesia, Levobupivacaine PCA group
- Volunteers
- 120 people
- Sponsor
- Osijek University Hospital
Hernia Inguinal
Pilot Study on the Effectiveness of a TAP-block for Inguinal Hernia Repair
An prospective double blinded randomised trial,whether the use of an perioperative echoguided unilateral TAP block has an superior effect on postoperative pain after open hernia inguinal repair compared to wound infiltration with…
- Trial name
- NCT01793571
- Testing
- TAP block
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dijklander Ziekenhuis
Thoracic Surgery
Epidural Levobupivacaine-sufentanil Versus Epidural Levobupivacaine and Intravenous Ketamine
Thoracic epidural analgesia is often proposed to thoracotomized patients. A local anesthetic and an opioid are generally associated to produce an epidural analgesia.
- Trial name
- NCT01320475
- Testing
- Sufentanil, Ketamine
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Hopital Foch
Pain
Study : LEVOBUPIVACAINE Versus Placebo
The locoregional anaesthesia is increasingly important in surgical practice, often allowing to simplify per- and post-operative analgesia.
- Trial name
- LEVOBU (NCT00621907)
- Testing
- chirocaine (Levobupivacaine), sodium chloride
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anesthetics Complications, Anesthetic Toxicity
PK/PD Levobupivacaine with and Without Epinephrine After Ultrasound Guided ESP Block
Currently there is no standardized management or single technique to manage postoperative pain after Video-assisted thoracic surgery (VATS), there are many options available ranging from intravenous opioids, morphine or fentanyl…
- Conditions
- Anesthetics Complications, Anesthetic Toxicity, Bupivacaine Overdose, Nerve Block
- Trial name
- NCT04799184
- Testing
- Levobupivacaine 0.25% with epinephrine 5 ug/ml, Levobupivacaine 0.25% without epinephrine 5 ug/ml
- Where
- Chile
- Volunteers
- 38 people
- Sponsor
- Pontificia Universidad Catolica de Chile
INFERTILITY
Analgesic Efficacy of Dexamethasone in Different Routes of Administration in Transverse Abdominis Plane Block
Transverse abdominis plane (TAP) block is a regional anaesthesia technique that provides analgesia to the parietal peritoneum as well as skin and muscles of the anterior abdominal wall.
- Trial name
- AEDDATB (NCT02838719)
- Testing
- Perineural Dexamethasone acetate, Intravenous dexamethasone acetate
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Preeclampsia
Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia
This study aims at evaluating the effect of adding magnesium sulphate epidurally as an adjunct to levobupivacaine on the quality of anesthesia and perioperative pain relief in patients with preeclampsia undergoing elective…
- Trial name
- NCT02699827
- Testing
- Levobupivacaine hydrochloride, Magnesium sulphate, Saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mohamed Sayed Abdelhafez
Upper Tracheal Resection, Tracheal Reconstruction Surgery
Local Wound Infiltration for Tracheal Reconstruction
Tracheal resection and reconstruction (TRR) is the treatment of choice for most patients with tracheal stenosis or tracheal tumors .The postintubation tracheal stenosis is the common indication for (TRR).The immediate…
- Trial name
- NCT02949661
- Testing
- Superficial cervical plexus block, Local wound infiltration
- Sponsor
- Mansoura University