Clinical trials: Levobupivacaine
Endoscopic Sinus Surgery, Fentanyl
Effect of Topically Administered Levobupivacaine- Fentanyl Versus Levobupivacaine- Dexamethasone Combination in the Control of Pain After Endoscopic Sinus Surgery
Chronic sinusitis (CRS) is a high incidence disease characterized by pus, nasal obstruction, olfactory disturbance, headache, and other symptoms, lasting for more than 12 weeks, with severe cases having ocular compression and…
- Trial name
- NCT05145543
- Testing
- Saline 0.9%, Levobupivacaine Hydrochloride, Fentanyl
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Hysterectomy, Laparoscopic Surgery
Transversus Abdominis Plane Block for Laparoscopic Hysterectomy
Purpose To evaluate whether adding a transversus abdominis plane block in patients undergoing elective laparoscopic hysterectomy reduces Patient-controlled analgesia (PCA) morphine requirements during the first 24 hours…
- Trial name
- NCT01552148
- Testing
- USguided bilateral TAP block, Morphine Patient Controlled Analgesia
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Istituti Ospitalieri di Cremona
Breast Tumors, Hypotension
Levobupivacaine and Lidocaine for Paravertebral Block Causes Greater Hemodynamic Oscillations Than Levobupivacaine
The purpose and the goal of this paper is to show whether the application of a combination of two local anesthetics, as opposed to the application of one local anesthetic at paravertebral block changes the hemodynamic variable.
- Conditions
- Breast Tumors, Hypotension, Bradycardia
- Trial name
- NCT02004834
- Testing
- levobupivacaine
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Caesarean Section
Ropivacaine 0.75% Versus Levobupivacaine 0.5% for Conversion of Labour Epidural
The aim of this trial is to compare the local anaesthetic ropivacaine to local anaesthetic levobupivacaine in converting the standard patient controlled labour epidural to provide anaesthesia for an emergency Caesarean section.
- Trial name
- RoLe (NCT01160965)
- Testing
- 0.5% levobupivacaine, 0.75% Ropivacaine
- Where
- United Kingdom
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Post Operative Pain
Intraperitoneal Instillation of Levobupivacaine With Morphine Versus Levobupivacaine With Magnesium Sulfate for Postoperative Analgesia
This is a prospective randomized study that included 60 patients and was divided into two equal groups of patients who were scheduled for LC, Ages 18 and 60 years, both sexes, ASA I-II and BMI 19 - 39.
- Trial name
- NCT05281081
- Testing
- intraperitoneal levobupivacaine and morphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Anesthesia
Comparison of 3 Different Density Levobupivacaine Solutions + Fentanyl for Spinal Anaesthesia for Caesarean Delivery.
The investigator's aim is to compare the efficacy of 3 levobupivacaine solutions with different density on spinal anesthesia for caesarean delivery.
- Trial name
- NCT03956303
- Testing
- Chirocaine %0.5, Chirocaine Heavy 40, Chirocaine Heavy 60
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Postoperative Pain
The Efficacy of Periarticular Single Drug Compared With Multimodal Drug Injection in Controlling Pain After TKA
The purpose of this study is to determine the periarticular multimodal drug injection has more efficacy for controlling pain after TKA than single anaesthetic drug injection.
- Trial name
- TKA (NCT01898052)
- Testing
- single anaesthetic drug, multimodal drug injection
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Thammasat University
Breast Cancer, Post Operative Pain
Dexmedetomidine Versus Dexamethasone as Adjuncts in Erector Spinae Plane Block in Modified Radical Mastectomy
The aim of this study is to evaluate the analgesic efficacy and safety of adding dexmedetomidine versus dexamethasone to levobupivacaine in ultrasound guided ESPB for patients undergoing modified radical mastectomy
- Trial name
- NCT05447949
- Testing
- Adjuncts to levobupivacaine in Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Preeclampsia
Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia
This study aims at evaluating the effect of adding magnesium sulphate epidurally as an adjunct to levobupivacaine on the quality of anesthesia and perioperative pain relief in patients with preeclampsia undergoing elective…
- Trial name
- NCT02699827
- Testing
- Levobupivacaine hydrochloride, Magnesium sulphate, Saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mohamed Sayed Abdelhafez
Analgesia, Epidural
Levobupivacaine for Epidural Analgesia in Labour
In a prospective randomised study involving primiparous women in spontaneous uncomplicated labour with cervical dilatation > 7 cm, epidural analgesia will be given with an initial volume of 20 mL anaesthetic solution, followed by…
- Trial name
- NCT00929682
- Testing
- Randomization between two referenced treatments
- Volunteers
- 136 people
- Sponsor
- University Hospital, Clermont-Ferrand
Vitreoretinal Surgery Under Sub-Tenon's Anesthesia
Dexmedetomidine as an Adjuvant for Sub-Tenon's Anesthesia
The investigator evaluated the motor and sensory block durations and the postoperative analgesic effects of adding dexmedetomidine to levobupivacaine for sub-Tenon's anesthesia in patients undergoing vitreoretinal surgery.
- Trial name
- Precedex (NCT02327156)
- Testing
- dexmedetomidine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Magrabi Eye & Ear Hospital
Neuromuscular Block
Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee Arthroplasty
The present study is designed to evaluate and compare the efficacy of intrathecal dexmedetomidine (DEX) as an adjuvant to Levobupivacaine in spinal anaesthesia and DEX's intravenous administration, without loading dose…
- Trial name
- NCT02966249
- Testing
- Levobupivacaine, Dexmetomidine intravenously, Normal Saline added intrathecally
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- KAT General Hospital
Laparoscopic Cholecystectomy, Postoperative Pain
Local Infiltration With Levobupivacaine During Laparoscopic Cholecystectomy
Randomized controlled trial on laparoscopic cholecystectomy. Interventional group: preincisional infiltration with levobupivacaine. Control group: no local infiltration.
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Local Infiltration, Levobupivacaine
- Trial name
- NCT04697329
- Testing
- Preincisional infiltration with levobupivacaine
- Where
- Spain
- Volunteers
- 233 people
- Sponsor
- Hospital Universitario de Móstoles
Recovery After Cleft Palate Surgery
Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate Surgery
A cleft deformity of the lip and/or palate is one of the commonest major birth defects. Primary surgery of cleft palates (CP) varies according to the different surgical teams.
- Trial name
- NCT02923869
- Testing
- Levobupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Arm Injuries, Anesthesia
Ultrasound-guided Supraclavicular Brachial Plexus Block in Elderly
The aim of this study is to determine the minimum effective volume of local anesthetic (50:50 mixture of 0.5% levobupivacaine and 2% lidocaine) required to produce an effective US-SCB for surgical anesthesia in 50% of patients…
- Trial name
- US-SCB (NCT01467596)
- Testing
- Elderly population, Middle aged population
- Where
- 2 sites in Croatia
- Volunteers
- 44 people
- Sponsor
- Šarić, Jadranka Pavičić, M.D.
Outpatient Rhinoplasty
Facial Block for Outpatient Rhinoplasty Analgesia
A bilateral facial block (infraorbital and infratrochlear) will be performed immediately after intubation in patients undergoing outpatient rhinoplasty with 2.5% levobupivacaine (intervention group) or saline as control.
- Trial name
- FABLORA (NCT01872728)
- Testing
- Bilateral facial block after general anesthesia before surgery
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Vitreoretinal Surgery, Cognitive Function Abnormal
The Effect of Retrobulbar Block for Eye Surgery on Brain Oxygenation and Cognitive Functions in Elderly Patients
The investigators measured changes in cerebral oxygen saturation (rSO2) and MMSE scores after retrobulbar block performed with levobupivacaine and lidocaine in patients undergoing vitreoretinal surgery.A total of 66 patients over…
- Conditions
- Vitreoretinal Surgery, Cognitive Function Abnormal, Intraoperative Monitoring
- Trial name
- NCT03189329
- Testing
- 2% lidocaine hydrochloride, 0.5% levobupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Cengiz KAYA
Fracture of Lower Limb
Comparing Heavy Levobupivacaine With Enantiomeric Excess of 50% and Heavy Racemic Bupivacaine.
The purpose of this study is to compare the non-inferiority between Heavy Levobupivacaine with Enantiomeric Excess of 50% and Heavy Racemic Bupivacaine During Spinal Anesthesia for Orthopedic Procedures in the Lower Limbs.
- Trial name
- NCT01308047
- Testing
- Bupivacaine
- Where
- 2 sites in Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Triple-negative Breast Cancer
Peritumoral and Periganglionic Infiltration of Levobupivacaine Prior to Conservative Surgery for Triple-negative Breast Cancer
Breast cancer is one of the most common cancers among women. One in eight women in France will develop breast cancer during their lifetime (Inca).
- Trial name
- EPPIL (NCT07458204)
- Testing
- LVB infiltration
- Where
- France
- Volunteers
- 760 people
- Sponsor
- Institut Jean-Godinot