Clinical trials: Levobupivacaine
Postoperative Pain, Inguinal Hernia Unilateral
Levobupivacaine and Postoperative Pain Relief
The study analysed direct levobupivacaine instillation in surgical wound and its effectiveness in postoperative pain control. Half participants received 0,5 % levobupivacaine and the other half received 0,9% saline solution
- Trial name
- NCT04869046
- Testing
- Instillation of levobupivacaine in surgical wound
- Where
- 2 sites in Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mother and Child Health Institute of Serbia Dr Vukan Cupic
Inguinal Hernia, Spinal Anesthesia
The Effect of Local Anesthetic and Clonidine on the Cutaneous Silent Period During Spinal Anesthesia
The cutaneous silent period is a non-invasive technique that gives insight into the function of thin A delta fibers and as such can be a complement to conventional electrophysiological methods used to study the peripheral nerves.
- Trial name
- NCT03121261
- Testing
- levobupivacaine, clonidine
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Elective Caesarean Section Surgeries
Intrathecal Levobupivacaine With Opioids for Caesarean Section
In this prospective, randomized, double-blind, controlled study, the aim was to compare the effect of adding fentanyl (10 µg) or sufentanil (2.5 µg) to levobupivacaine (2.2±0.2 ml 0.5%) on the intraoperative anesthesia quality…
- Trial name
- NCT01858090
- Testing
- Control Group Chirocaine, Group Fentanyl, Group sufentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Baskent University
Musculoskeletal Diseases or Conditions
Prospective RCT Lidocaine & Levobupivacaine on Block Dynamics After Subparaneural Popliteal Sciatic Nerve Block
Sciatic nerve block at the popliteal fossa is indicated for foot or ankle surgery, and the introduction of ultrasound guidance (USG) has improved the ease and accuracy of the performance of this block.
- Trial name
- NCT04397484
- Testing
- 0.5% Levobupivacaine, 2% Xylocaine with adrenaline 1:200,000
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Breast Cancer, Post Operative Pain
Dexmedetomidine Versus Dexamethasone as Adjuncts in Erector Spinae Plane Block in Modified Radical Mastectomy
The aim of this study is to evaluate the analgesic efficacy and safety of adding dexmedetomidine versus dexamethasone to levobupivacaine in ultrasound guided ESPB for patients undergoing modified radical mastectomy
- Trial name
- NCT05447949
- Testing
- Adjuncts to levobupivacaine in Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Total Hip Arthroplasty, Analgesia
Spinal Nalbuphine for Analgesia in Total Hip Arthroplasty
60 patients ASA I-III, undergoing total hip arthroplasty were randomly assigned, into one of two groups, namely group E (n=30), where levobupivacaine will be administeral intrathecally ; and group N (n=30), where levobupivacaine…
- Trial name
- NCT06577155
- Testing
- Levobupivacaine, Levobupivacaine plus nalbuphine
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Asklepieion Voulas General Hospital
Spermatic Cord Block
Addition of Neostigmine to Levobupivacaine
Using the spermatic cord block has been of great advantage, as it has been cost saving, efficient technique whether used inon its own or combination with a sedative or .
- Trial name
- NCT04492319
- Testing
- Control Test, Neostigmine
- Where
- Egypt
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Cairo University
Regional Anesthesia
Tramadol Versus Dexamethasone as Adjuvant to Levobupivacaine Supraclavicular Block
The investigator's aim will be to compare the efficacy of perineural tramadol and dexamethasone added to levobupivacaine in prolonging postoperative analgesia in patient undergoing open reduction and internal fixation for forearm…
- Trial name
- NCT04551833
- Testing
- Levobupivacaine
- Volunteers
- 60 people
- Sponsor
- Assiut University
Pain
Intraperitoneal Application of Levobupivacaine During Laparoscopic Surgery in Kids.
Pain after laparoscopic surgery has been associated with surgical manipulations, including intraperitoneal insufflation of carbon dioxide (CO2), resulting in peritoneal stretching, diaphragmatic irritation, changes in…
- Trial name
- NCT02037711
- Testing
- Levobupivacaine 0.5%, Normal saline
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Outpatients, General Surgery
Comparing the Effects of Levobupivacaine and Bupivacaine in Saddle Spinal Anesthesia
İn this study; it was aimed to investigate the effects of equipotent doses of hyperbaric bupivacaine and hyperbaric levobupivacaine in outpatient anorectal surgery under saddle block.
- Conditions
- Outpatients, General Surgery, Anorectal Disorder, Anesthesia
- Trial name
- NCT04245774
- Testing
- Levobupivacaine (as Levobupivacaine Hydrochloride) 75 Mg/10 mL Solution for Injection Ampoule, Bupivacaine/Dextrose
- Volunteers
- 60 people
- Sponsor
- Gazi University
Caesarean Section
Ropivacaine 0.75% Versus Levobupivacaine 0.5% for Conversion of Labour Epidural
The aim of this trial is to compare the local anaesthetic ropivacaine to local anaesthetic levobupivacaine in converting the standard patient controlled labour epidural to provide anaesthesia for an emergency Caesarean section.
- Trial name
- RoLe (NCT01160965)
- Testing
- 0.5% levobupivacaine, 0.75% Ropivacaine
- Where
- United Kingdom
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Hemodynamic Instability, Epidural
Evaluate Efficacy Levobupivacaine 0.125% Versuss Ropivacaine 0.2% in Hemodynamic Alterations in Labor and Fetal Repercussions
INTRODUCTION: Most studies on analgesia in pregnant women in labor mainly evaluate the effect of anesthetics on pain, mentioning hypotension as a side effect without investigating its impact on fetal well-being.
- Conditions
- Hemodynamic Instability, Epidural, Pregnancy, Fetal Cardiac Disorder
- Trial name
- NCT05877131
- Testing
- Levobupivacaine, Ropivacaine
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Hernia Inguinal
Pilot Study on the Effectiveness of a TAP-block for Inguinal Hernia Repair
An prospective double blinded randomised trial,whether the use of an perioperative echoguided unilateral TAP block has an superior effect on postoperative pain after open hernia inguinal repair compared to wound infiltration with…
- Trial name
- NCT01793571
- Testing
- TAP block
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dijklander Ziekenhuis
Hypotension Drug-Induced, Cesarean Section Complications
Spinal Anesthesia in Caesarean Section
Spinal anesthesia is a safe technique, widely used and tested in the gynecological field, so as to be considered the first choice technique in cesarean section, which allows to quickly obtain a valid sensor and motor block.
- Conditions
- Hypotension Drug-Induced, Cesarean Section Complications, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Bradycardia
- Trial name
- NCT03743870
- Testing
- Levobupivacaine, Bupivacaine
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele
Tizanididne, Levobupicaine
Comparison of Analgesic Efficacy of Intrathecal Levobupivacaine With and Without Oral Tizanidine in Lower Limb Surgeries: A Prospective Randomized Study
Tizanidine, alpha-2 adrenergic receptor agonist, provides analgesic and hemodynamic benefits, which could enhance the efficacy of local anaesthetics.
- Conditions
- Tizanididne, Levobupicaine, Lower Limb Surgery, Pain, Chronic
- Trial name
- NCT07310628
- Testing
- Tizanidine
- Where
- India
- Volunteers
- 64 people
- Sponsor
- All India Institute of Medical Sciences
Pain, Postoperative
Postoperative Analgesic Effects of Infraorbital Nerve Block in Cleft Palate Surgery
Cleft palate repair is a common surgery in children.. As such children with cleft palate tend to have a compromised airway due to associated congenital anomalies like Pierre Robin syndrome, Treacher Collins syndrome etc.
- Trial name
- NCT04212611
- Testing
- INFRA ORBITAL BLOCK
- Where
- India
- Volunteers
- 80 people
- Sponsor
- All India Institute of Medical Sciences, Rishikesh
Post Operative Analgesia
Postoperative Pain Control Using ON-Q Painbuster Pump
This study is a blinded randomised study of slow release levobupivacaine vs saline for women undergoing day case operative pelvic laparoscopy.
- Trial name
- NCT01184794
- Testing
- levobupivacaine
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Ashford and St. Peter's Hospitals NHS Trust
INFERTILITY
Analgesic Efficacy of Dexamethasone in Different Routes of Administration in Transverse Abdominis Plane Block
Transverse abdominis plane (TAP) block is a regional anaesthesia technique that provides analgesia to the parietal peritoneum as well as skin and muscles of the anterior abdominal wall.
- Trial name
- AEDDATB (NCT02838719)
- Testing
- Perineural Dexamethasone acetate, Intravenous dexamethasone acetate
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Postoperative Pain, Caudal Anesthesia
Effect of Intravenous Versus Caudal Dexmedetomidine on Perfusion Index and Hemodynamic Responses in Children Undergoing Infraumbilical Surgery
Caudal anesthesia is widely used to provide pain relief for children undergoing surgery below the navel (infraumbilical surgery).
- Conditions
- Postoperative Pain, Caudal Anesthesia, Peripheral Perfusion, Pediatric Surgery
- Trial name
- NCT07852039
- Testing
- Caudal Dexmedetomidine, Intravenous Dexmedetomidine
- Volunteers
- 100 people
- Sponsor
- Assiut University
Anesthesia, Conduction, Surgery
A Randomised Comparison on the Dose Requirement Between, Levobupivacaine, Ropivacaine and Bupivacaine in Intrathecal Anaesthesia
To determine and compare the effective intrathecal dose of levobupivacaine, ropivacaine and bupivacaine for 50% of patients in lower limb surgery
- Trial name
- NCT00636974
- Testing
- Combined spinal epidural anaesthesia
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Hospital Authority, Hong Kong