Clinical trials: Lens Diseases
Cataract
NPI-002 Intravitreal Implant for the Delay of Cataract Progression
This study will examine the safety and efficacy NPI-002 intravitreal implants post vitrectomy.
- Trial name
- NCT05026632
- Testing
- NPI-002 Intravitreal Implant
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- Nacuity Pharmaceuticals, Inc.
Myopia
Study of ACUVUE® ADVANCE® PLUS Contact Lenses.
The purpose of this study is to compare ACUVUE® ADVANCE® Plus contact lenses made prior to process qualification (prePQ) against the ACUVUE® ADVANCE® Plus lenses made after the process qualification (postPQ).
- Trial name
- NCT01244893
- Testing
- Acuvue Advance Plus prePQ, Acuvue Advance Plus postPQ
- Where
- 3 sites in United States
- Volunteers
- 44 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Astigmatism
Clinical Evaluation of Two Monthly Replacement Silicone Hydrogel Contact Lenses
The purpose of this study is to evaluate differences in the comfort at the end of the month between Air Optix® lenses versus Biofinity® lenses in habitual daily wear symptomatic soft contact lens wearers.
- Trial name
- NCT01629693
- Testing
- Lotrafilcon B contact lenses, Comfilcon A contact lenses
- Volunteers
- 398 people
- Sponsor
- Alcon Research
Presbyopia
CLEAR CARE® PLUS for Presbyopic Contact Lens Wearers
The purpose of this study is to evaluate CLEAR CARE® PLUS (CCP) compared to non-HYDRAGLYDE® multi-purpose contact lens solutions in presbyopes currently wearing soft contact lenses and experiencing symptoms of dryness.
- Trial name
- NCT02965833
- Testing
- 3% hydrogen peroxide solution with HydraGlyde® Moisture Matrix, Habitual Multi-Purpose Contact Lens Solution, Habitual Contact Lenses
- Volunteers
- 126 people
- Sponsor
- Alcon, a Novartis Company
Cataract, Lens Opacities
PMCF Retrospective Study Outcomes of a Monofocal Toric Intraocular Lens
This is a monocentric retrospective, open-label clinical study in patients after unilateral or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC and executed only with standard of care…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- NCT05055076
- Testing
- PODEYE TORIC
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Beaver-Visitec International, Inc.
Myopia
Fitting Evaluation of Hydrogel and Silicone Hydrogel Sphere Design Contact Lenses
The aim of this non-dispensing fitting study is to evaluate the short term lens fit, vision performance of three monthly replacement sphere lenses.
- Trial name
- NCT03098745
- Testing
- Omafilcon A, Somofilcon A, Omafilcon A - Proclear (PC)
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
BIOCLEAN MPS (Multi-Purpose Solution) VII in Combination With Biofinity Lens: A Two Week Crossover Study
Two week, Open Label, randomized, bilateral, crossover, 1 week of daily wear in each combination (lens / disinfecting cleaning system).
- Trial name
- NCT02537730
- Testing
- Bioclean MPS VII, Aosept Clearcare, comfilcon A
- Where
- 3 sites in Japan
- Volunteers
- 33 people
- Sponsor
- CooperVision, Inc.
Astigmatism, Ametropia
Optimization for Toric Contact Lenses
The aim of this study is to evaluate the agreement between subjective and objective toric lens prescriptions.
- Trial name
- NCT07557030
- Testing
- Lens 1 ( stenfilcon A ), Lens 2 ( comfilcon A )
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- CooperVision International Limited (CVIL)
Cataract
DisCoVisc Versus DuoVisc, Healon5 and AmVisc Plus
A comparison of the ability of DisCoVisc to that of other ophthalmic viscosurgical devices (OVDs) (DuoVisc, Healon5 or Amvisc PLUS) regarding endothelial protection and anterior chamber space maintenance during non-eventful…
- Trial name
- NCT00712244
- Testing
- DisCoVisc, DuoVisc, Healon5
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Myopia
Dispensing Evaluation of Printed Etafilcon A With Polyvinylpyrrolidone (PVP)
The purpose of this study is to evaluate the lens fit (mechanical and cosmetic lens fit) of the printed etafilcon A with polyvinylpyrrolidone (PVP).
- Trial name
- NCT01180777
- Testing
- etafilcon A (A), etafilcon A (B), etafilcon A (C)
- Where
- 6 sites in United States
- Volunteers
- 95 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Allergic Conjunctivitis
Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers
The purpose of this study is to evaluate the safety of a novel contact lens in healthy normal volunteers
- Trial name
- NCT00569777
- Testing
- K-Lens (generic name not established) and Ketotifen
- Where
- 3 sites in United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Vistakon Pharmaceuticals
Astigmatism
Orientation Characteristics of Daily Disposable Toric Contact Lenses
Brief summary: Approximately 30 soft toric contact lens adapted subjects will be enrolled in this feasibility, bilateral, randomized, double-masked (subject and investigator), repeated measures insertion study.
- Trial name
- NCT06069609
- Testing
- kalifilcon A Daily Disposable Toric, Acuvue Oasys 1-Day for Astigmatism
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Cataracts, Meibomian Gland Dysfunction (MGD)
A Post-Market Evaluation of LipiFlow Treatment in Cataract Surgery Practice
This is a post-market, prospective, randomized, multi-center, bilateral, open-label, cross-over, comparative clinical study. Study group will undergo preoperative LipiFlow treatment and Control group will not receive preoperative…
- Trial name
- NCT03708367
- Testing
- LipiFlow Thermal Pulsation System
- Where
- 5 sites in United States
- Volunteers
- 117 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Refractive Error
Evaluation of Vision Effects of a Cosmetic Tinted Hydrogel Contact Lens
Subjects will wear 2 of 2 study contact lenses for a wearing time of approximately three to four hours at each of the visits in order to take measurements on binocular functional visual performance.
- Trial name
- NCT02886923
- Testing
- Hioxifilcon A Test, Hioxifilcon A With Cosmetic Ring Control
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Clinical Performance of Existing Wearers of Avaira Sphere Following a Refit With Clariti Elite Sphere
The aim of this dispensing study is to evaluate the clinical performance of existing wearers of Avaira sphere lenses following a refit with Clariti Elite sphere over 4 weeks of daily wear.
- Trial name
- NCT02248727
- Testing
- somofilcon A
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Cataract
Evaluation of Clinical Outcomes Following Implantation of a Sub-2mm Hydrophilic MICS Intraocular Lens
The objective of this study is to evaluate clinical outcomes following sub-2 mm micro-incision cataract surgery (MICS) and intraocular lens (IOL) implantation.
- Trial name
- NCT01615861
- Testing
- IOL implantation
- Where
- France
- Volunteers
- 103 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Refractive Error
Multi-Center Clinical Evaluation of Two Daily Disposable Contact Lenses
The purpose of this study is to compare the subjective performance of two daily disposable contact lenses with respect to comfort and handling.
- Trial name
- NCT01898260
- Testing
- Ultrafilcon B contact lens, Stenfilcon A contact lens
- Where
- United Kingdom
- Volunteers
- 89 people
- Sponsor
- Alcon Research
Cataracts, Presbyopia
Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens
The purpose of this study is to evaluate the safety and performance of the SBL-3 intraocular lens.
- Trial name
- NCT02487160
- Testing
- SBL-3 multifocal intraocular lens, Control monofocal intraocular lens
- Where
- 13 sites in United States
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Presbyopia
A Study to Evaluate the Feasibility of a High Add Multi Focal Contact Lens
The objective of this study is to evaluate the product performance of the investigational multifocal high add soft contact lens compared with PureVision Multi-focal contact lens on a daily wear basis.
- Trial name
- NCT01518868
- Testing
- Investigational contact lens, PureVision contact lens
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
Quantification of the Visual Benefits of Soft Toric Contact Lenses Compared to Soft Spherical Contact Lenses
The aim of this work is to undertake a range of vision-related measures with soft toric contact lenses soft spherical contact lenses and spectacle lens correction across a range of levels of astigmatism.
- Trial name
- NCT04613882
- Testing
- Soft Toric Custom Made Contact lens, Soft Spherical Contact Lenses, Spectacle Correction
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
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