Clinical trials: Lens Diseases
Wrinkle, Rosacea
Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Evaluate the Cutera excel V™ Laser with Green Genesis and a Micro-Lens Array (MLA) Attachment
- Conditions
- Wrinkle, Rosacea, Scarring
- Trial name
- NCT03424304
- Testing
- Excel V™ Laser With Green Genesis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Cataract
Tobramycin-Dexamethasone Versus Tobramycin-Dexamethasone Plus Ketorolac After Phacoemulsification Surgery
This randomized controlled trial compares two regimens of topical therapy: tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon), one drop four times/day combination of tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon)…
- Trial name
- NCT00992355
- Testing
- Tobramycin 0.3% - Dexamethasone 0.1%, Tobramycin 0.3% - Dexamethasone 0.1% plus Ketorolac tromethamine 0.5%
- Where
- Greece
- Volunteers
- 97 people
- Sponsor
- Veroia General Hospital
Cataract
Comparison of Postoperative Visual Acuity and Spectacle Independence Between the Tecnis Multifocal Intraoculer Lens (IOL) and the Crystalens Accommodating IOL
Comparison of postoperative visual acuity and spectacle independence between the Tecnis Multifocal Intraoculer Lens (IOL) and the crystalens Accommodating IOL
- Trial name
- NCT01275118
- Testing
- Tecnis Multifocal IOL, crystalens Accommodating IOL
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Mark Packer, MD, FACS
Diabetic Macular Edema
IVI Aflibercept Before and After Phaco in DME.
To study whether or not cataract surgery should be deferred until treating the co-existing diabetic macular edema (DME) using intravitreal (IVI) anti-vascular endothelial growth factor (anti-VEGF).
- Trial name
- NCT05731089
- Testing
- Phacoemulsification with IVI of aflibercept
- Where
- Kuwait
- Volunteers
- 40 people
- Sponsor
- Al Hadi Hospital
Myopia, Myopia; Refractive Error
Efficacy and Visual Quality of Orthokeratology Lenses With Different Designs
Orthokeratology (ortho-k) lens is very effective in slowing down axial elongation in myopic children by 30% to 63% when compared to children wearing single-vision spectacles or contact lenses.
- Trial name
- NCT06825585
- Testing
- Orthokeratology with 5.0mm back optical zone diameter, Orthokeratology with a 6.2 mm back optical zone diameter
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Yang
Cataract
Evaluation of the Rotational Stability
To evaluate rotational stability of the investigational device implanted after cataract surgery.
- Trial name
- NCT03247751
- Testing
- intraocular lens
- Volunteers
- 95 people
- Sponsor
- Nidek Co. LTD.
Aphakia, Presbyopia
Post-Market Clinical Study of the PanOptix Intraocular Lens (IOL) in a Chinese Population
The primary objective of this clinical study is to assess the clinical performance of the PanOptix IOL in a Chinese population.
- Trial name
- NCT04755231
- Testing
- AcrySof IQ PanOptix Presbyopia Correcting IOL, Cataract surgery
- Where
- 9 sites in China
- Volunteers
- 181 people
- Sponsor
- Alcon Research
Cataract, Glaucoma
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- NCT07218796
- Testing
- Bimatoprost Implant System, SpyGlass IOL, Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- SpyGlass Pharma, Inc.
Presbyopia
Comparison of Two Soft Bifocal Contact Lenses
The purpose of the study is to compare the visual performance of two soft bifocal contact lenses.
- Trial name
- NCT00724945
- Testing
- balafilcon A, senofilcon A
- Where
- 6 sites in United States
- Volunteers
- 113 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Tunnel Construction Course Pilot Assessment of Simulation-based Training Effectiveness
TCC-PASTE is a randomised controlled trial comparing a simulation based training curriculum with standard training for ophthalmology residents learning to perform tunnel construction in manual small incision cataract surgery.
- Trial name
- TCC-PASTE (NCT04450420)
- Testing
- Simulation based curriculum, Standard training
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- HelpMeSee Inc.
Cataract; Complicata, Posterior Capsule Tear
CT Lucia 601 IOL Implantation in the Sulcus
To perform a retrospective investigation of the CT Lucia 601 IOL implantation in the sulcus
- Conditions
- Cataract; Complicata, Posterior Capsule Tear, Lens Dislocation
- Trial name
- CLUS (NCT04796662)
- Where
- Belgium
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Respiratory Tract Diseases, Respiratory Hypersensitivity
Effects Of Ciclesonide And Beclomethasone On Lens Opacification In Adult Subjects With Moderate To Severe Persistent Asthma
The primary objective is to demonstrate the non-inferiority of ciclesonide compared to beclomethasone-HFA in the occurrence of Class 1 lens event for nuclear (NO), cortical (C), or posterior subcapsular (P) lens opacification…
- Conditions
- Respiratory Tract Diseases, Respiratory Hypersensitivity, Asthma
- Trial name
- NCT00254956
- Testing
- ciclesonide (XRP1526)
- Where
- France
- Volunteers
- 1,568 people
- Sponsor
- Sanofi
Cataract
To Compare Early Rotation of Two Extended Depth of Focus Intraocular Lenses
To demonstrate that the Carl Zeiss Meditec (CZM) Extended depth of focus (EDOF) Intraocular lens (IOL) is superior to the competitor EDOF IOL with respect to Rotational Stability.
- Trial name
- VENUStoric (NCT03839420)
- Testing
- CZM IOL, Competitor IOL
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Carl Zeiss Meditec AG
Presbyopia Correction, Presbyopia
Presbyopic Wear Experience With Multifocal Lenses Compared to Single Vision Lenses and Reading Glasses
The purpose of the study is to assess participant experience when wearing multifocal contact lenses compared to spherical contact lenses with reading glasses.
- Trial name
- NCT07218731
- Testing
- Multifocal contact lenses, Spherical contact lenses
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Aphakia, Cataract
Registry Study on Intraocular Lenses Manufactured by Teleon Surgical B.V.
This is a retrospective, observational (Registry) study aiming to collect safety and performance data on the use of intraocular lenses (IOLs) manufactured by Teleon Surgical B.V. according to routine practice.
- Conditions
- Aphakia, Cataract, Clear Lens Exchange, Refractive Lens Exchange
- Trial name
- NCT05290870
- Testing
- Posterior-chamber intraocular lens
- Where
- Netherlands
- Volunteers
- 2,183 people
- Sponsor
- Teleon Surgical B.V.
Ametropia
Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Hexafocon A
This will be an up to six months, subject-masked, contralateral, parallel-group, randomised, daily wear study. All subjects will wear the Test lens in one eye and the Control lens in the other eye.
- Trial name
- NCT04525170
- Testing
- HPT treatment, untreated
- Where
- 2 sites in Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Contamac Ltd
Cataract
Zeiss® IOLMaster 700 Corneal Topography Module Comparison With Schwind's Sirius Corneal Topography®
In order to determine the intraocular lens to be implanted during cataract surgery, keratometry and axial length must be measured in preoperative. The axial length is obtained by ocular ultrasound mode B.
- Trial name
- VIMECT (NCT05414773)
- Testing
- measurement of axial length and keratometry by sonographers with a topographic module
- Volunteers
- 100 people
- Sponsor
- Edouard KOCH
Myopia
Pilot Study on the Adaptation and Tolerance of Essilor® Myopia-control Spectacle Lenses
This observational pilot study aims to evaluate the adaptation and tolerance of Essilor® Stellest® myopia-control spectacle lenses in children with progressive myopia.
- Trial name
- STELLAR (NCT07340931)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Nantes University Hospital
Cataract With Pre-existing Regular Corneal Astigmatism
Influence of Implantation Technique on Rotational Stability of a Frosted-Haptic Toric Intraocular Lens: A Prospective Contralateral-Eye Study
This prospective, randomized contralateral-eye study evaluates whether the implantation technique influences the rotational stability and refractive outcomes of the TECNIS Eyhance™ Toric II intraocular lens (IOL) during cataract…
- Trial name
- NCT07768722
- Testing
- OVD-assisted Implantation, BSS-assisted hydroimplantation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Inflammation, Pain
Efficacy and Safety of XG-102 in Reduction of Post-cataract Surgery Intraocular Inflammation
The purpose of this study is to evaluate the clinical efficacy and safety of XG-102 (900µg) compared to vehicle in the treatment of subjects with inflammation and pain following cataract surgery.
- Conditions
- Inflammation, Pain, Cataract
- Trial name
- NCT02235272
- Testing
- XG-102
- Where
- United States
- Volunteers
- 339 people
- Sponsor
- Xigen SA
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