Clinical trials: Leg Elevation
Post Induction Hypotension
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) is widely used in thoracic surgery due to small incisions, low stress response, and high patient tolerance.
- Trial name
- NCT07374458
- Testing
- Esketamine, Bilateral Lower Limb Elevation
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Maternal Hypotension Associated With Spinal Anesthesia During Cesarean Section
The Effect of Compression Stockings and Leg Elevation on Hemodynamic Stability in Elective Cesarean Sections Under Spinal Anesthesia: A Single-Blind Randomized Controlled Trial
Aim: This study aimed to evaluate the effects of compression stockings and leg elevation on maternal intraoperative hypotension, vasopressor requirement, and neonatal well-being parameters in women undergoing elective cesarean…
- Trial name
- NCT07534891
- Testing
- compression stockings, Leg elevation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Seçil Yavaş
Healthy Adult, Cardiac Output
Effect of Systematic and Sequential Leg Elevation on Cardiac Output in Healthy Volunteers
Passive leg raising (PLR) transiently increases venous return and cardiac preload and is commonly used to predict fluid responsiveness in critically ill patients.
- Conditions
- Healthy Adult, Cardiac Output, Hemodynamic, Passive Leg Raising
- Trial name
- SYSLE-1 (NCT07860515)
- Testing
- Passive Leg Raising, Non-Invasive Ventilation
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Acute Ischemic Stroke
LEG-UP Feasibility Study: Elevated Leg Positioning For Acute Moderate Ischemic Stroke
Augmentation of penumbral perfusion through nonpharmacological hemodynamic interventions such as patient positioning may offer a pragmatic approach to improve outcomes in acute ischemic stroke (AIS).
- Trial name
- LEG-UP (NCT07483580)
- Testing
- Elevated Leg Positioning
- Where
- Philippines
- Volunteers
- 50 people
- Sponsor
- Bonifacio C. Pedreogsa II
Peripheral Arterial Disease
Near Infrared Spectroscopy Imaging of Change in Tissue Oxygenation to Assess Peripheral Artery Disease
This is a proof-of-concept study with exploratory objective to assess whether superficial tissue oxygenation patterns measured by Snapshot NIRS, in conjunction with the Provocative Elevation Maneuver of the Lower Extremity…
- Trial name
- NCT07397494
- Testing
- Observational study only.
- Volunteers
- 200 people
- Sponsor
- Kent Imaging Inc
Leg Edema, Venous; Return (Anomaly)
Elevate to Alleviate Evidence Based Study
Venous return in the circulatory system of lower limbs results from the interaction of several mechanisms, and reflects the balance between blood inflow and outflow.
- Conditions
- Leg Edema, Venous; Return (Anomaly), Leg Elevation
- Trial name
- ETA (NCT04514939)
- Testing
- Elevation of the legs during bed rest
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Catanzaro
Intraoperative Hypotension, Cerebral Ischemia
Effect of Leg Elevation on Prevention of Intraoperative Hypotension During Beach Chair Position
The aim of this study is to evaluate the effect of leg elevation on the prevention of intraoperative hypotension during shoulder surgery in the Beach-chair position.
- Conditions
- Intraoperative Hypotension, Cerebral Ischemia, Shoulder Disease
- Trial name
- NCT03393559
- Testing
- leg elevation
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Leukodystrophy, White Matter Disease
The Myelin Disorders Biorepository Project
The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects.
- Conditions
- Leukodystrophy, White Matter Disease, Leukoencephalopathies, 4H Syndrome
- Trial name
- MDBP (NCT03047369)
- Where
- 23 sites in United States
- Volunteers
- 12,000 people
- Sponsor
- Children's Hospital of Philadelphia
Infants or Children Undergoing Open Heart Surgery
The Influence of Passive Leg Elevation on the Cross-sectional Area of the Internal Jugular Vein in Infants or Young Children Undergoing Open Heart Surgery
The trendelenburg position is usually applied to increase the cross-sectional area of the IJV. However, trendelenburg position requires a tilt table to place the head in the down position.
- Trial name
- NCT01401920
- Testing
- leg elevation, Trendelenburg position, Trendelenburg position + passive leg elevation
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Leukodystrophy, White Matter Disease
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophies, and other heritable disorders of the white matter of the brain, were previously resistant to genetic characterization, largely due to the extreme genetic heterogeneity of molecular causes.
- Conditions
- Leukodystrophy, White Matter Disease, 4H Syndrome, Adrenoleukodystrophy
- Trial name
- NCT02699190
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Philadelphia
Hip Fracture
Troponin Elevation in the Elderly Patient With Hip Fracture
Elevated troponin is powerful and independent adverse prognostic marker in patient with ACS. However, non specific (non cardiac) troponin elevation is a common finding among hospitalized patients and worse prognosis too.
- Trial name
- NCT00647309
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Hypotension, Labor Complication
Leg Elevation to Prevent Hypotension During Labor
When hypotension is related to epidural placement, this can occur within 15-60 minutes after placement. The purpose of this study is to build upon this preliminary work and to use a randomized controlled trial to examine the…
- Trial name
- NCT05674838
- Testing
- Leg Elevation
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
STEMI - ST Elevation Myocardial Infarction
Noninvasive Artificial Venous Stasis for Reperfusion in STEMI
This prospective, randomized study was designed to evaluate whether the noninvasive artificial venous stasis / RE-START procedure, administered prior to primary percutaneous coronary intervention, increases the frequency of…
- Trial name
- RE-START (NCT07689591)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Firat University
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Leg Elevation for Prevention of Post Spinal Hypotension in Cesarean Section
Prospective trial including full term parturients scheduled for a cesarean section under spinal anesthesia. patients are being randomly assigned into 2 groups: LE group: will be positioned in 15° left tilt with leg elevation with…
- Trial name
- NCT03488277
- Testing
- leg elevation
- Where
- Tunisia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Hip Fracture
Troponin Elevation in Consecutive Patients With Hip Fracture
The aims of this study is to study the occurrence of the troponin elevations, ECG changes, and cardiac symptoms in unselected consecutive patients with hip fracture. Followup will be carried out up to one year period.
- Trial name
- NCT01015105
- Testing
- observation
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Turku University Hospital
Propofol Induced Hypotension
Comparison of Leg Elevation and Leg Wrapping in the Prevention of Propofol Induced Hypotension
Propofol is an intravenous anaesthetic agent used for both induction and maintenance of anaesthesia. An important adverse effect is the significant fall in blood pressure.
- Trial name
- NCT02845921
- Testing
- leg elevation, leg wrapping, control
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Nitte University
Post Induction Hypotension
Lower Extremity Elevation to Minimize Hemodynamic Instability During Induction of General Anesthesia
The purpose of this study is to determine if lower extremity elevation (LEE) will reduce the incidence of postinduction hypotension, to compare the utilization of vasoactive medications after induction in patients with LEE and…
- Trial name
- NCT06513169
- Testing
- Group 1: LEE
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hip Fracture
Troponin T Elevation in Patient Undergoing Hip Fracture Surgery
Background: Patients undergoing hip fracture surgery are elderly and usually have co-morbidities; hence they are at risk for perioperative MI.
- Trial name
- NCT01352754
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Post-induction Hypotension
Comparison of the Hemodynamic Effect of Three Positions During Induction of Anesthesia
The most common methods for prevention of post-induction hypotension are preoperative fluid loading and vasopressors. Leg elevation induces an intrinsic transfusion of 150 mL blood from the lower limbs to the central fluid…
- Trial name
- NCT03996213
- Testing
- head down position, leg elevation position
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Cairo University
Spinal Hypotension, Hypoperfusion
The Influence of Leg Elevation on Noradrenaline Requirements During Cesarean Delivery
Spinal anesthesia is a widely chosen technique in obstetric theaters due to several advantages, however sympathetic block results in hypotension that carry several consequences on maternal and fetal health, thus early prediction…
- Trial name
- NCT06822699
- Testing
- Leg elevation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University