Clinical trials: Large for Gestational Age Infant
Body Composition, Feeding; Difficult, Newborn
Role of Body Composition in Large for Gestational Age Infants (LGA) With Oral Feeding Difficulty
Large for Gestational Age (LGA) infants have excess fat-mass (FM) proportion secondary to prolonged in utero exposure to an energy-rich environment.
- Conditions
- Body Composition, Feeding; Difficult, Newborn, Nutrition Disorder, Infant
- Trial name
- NCT04599010
- Testing
- Dietary intervention
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Childhood Overweight
Effects of Lifestyle Intervention on Childhood Outcomes in LGA Infants
Large-for-gestational-age (LGA) infants have a higher risk of metabolic disease later in life, and their postnatal growth in early childhood may be associated with long-term adverse outcomes.
- Trial name
- NCT04661449
- Testing
- Comprehensive lifestyle intervention
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Small for Gestational Age Infant, Large for Gestational Age Infant
"Fetal gRowth AbnorMality dEtection Trial"
The present trial intends to assess the diagnostic accuracy of symphysis fundal height (SFH) as opposed to SFH combined with point of care ultrasound to measure the fetal abdominal circumference (POC-US-AC) in identifying small…
- Conditions
- Small for Gestational Age Infant, Large for Gestational Age Infant, Oligohydramnios, Polyhydramnios
- Trial name
- FRAME (NCT05043753)
- Testing
- Point of care ultrasound to measure the fetal abdominal circumference (POC-US-AC)
- Where
- 3 sites in Italy
- Volunteers
- 1,566 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Large for Gestational Age Baby, Macrosomia, Fetal
A First Trimester Prediction Model for Large for Gestational Age Infants: a Preliminary Study
Large for gestational age infants (LGA) have increased risks of adverse short-term perinatal outcomes. This study aims to develop a multivariable prediction model for the risk of giving birth to a LGA baby, by using biochemical…
- Trial name
- PreMoLGA (NCT04838431)
- Testing
- Blood sample and ultrasound at first trimester
- Where
- Italy
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Small for Gestational Age at Delivery, Post-term Infant, Not Heavy-for-dates
Breast Milk Zinc Transfer to Appropriate- and Small-for-gestational-age Bangladeshi Infants
Data collected from this study will provide information on the breast milk zinc concentration, maternal and infant zinc status, and transfer of zinc from mothers breast milk to infants during first six months of life.
- Trial name
- NCT01728766
- Testing
- Small for gestational age at delivery, Post-term Infant, Not Heavy-for-dates
- Where
- Bangladesh
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Gestational Diabetes Mellitus in Pregnancy, Macrosomia, Fetal
Late Gestational Diabetes Mellitus Diagnosis in Obese Women
In the current work, we aim to perform a prospective study that will investigate the relationship between maternal obesity (BMI >30 kg/m2) and morbid obesity (BMI >35 kg/m2) with a late GDM diagnosis (>32 weeks), with an emphasis…
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Macrosomia, Fetal, Dystocia, Shoulder, Neonatal Jaundice
- Trial name
- NCT05510518
- Testing
- oral glucose tolerance test (OGTT)
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Western Galilee Hospital-Nahariya
Neonatal Hypoglycemia, Infant, Small for Gestational Age
Effect of Tahneek on Hypoglycemia in Newborn Infants
Tahneek is an Arabic word which means putting something sweet such as dates, in the infant's mouth after the birth. Neonatal hypoglycemia is common in the first few days after birth.
- Conditions
- Neonatal Hypoglycemia, Infant, Small for Gestational Age, Macrosomia, Fetal, Intrauterine Growth Restriction
- Trial name
- THIN (NCT03726697)
- Testing
- Tahneek
- Where
- Saudi Arabia
- Volunteers
- 324 people
- Sponsor
- King Abdullah International Medical Research Center
Maternal Obesity Complicating Pregnancy, Birth,or Puerperium, Gestational Diabetes Mellitus
An Early-customized Low Glycaemic-index (GI) Diet Prevents LGA Babies in Overweight/Obese Pregnant Women
High pre-pregnancy body mass index (BMI) and excessive gestational weight gain (GWG) are associated with many unfavourable maternal and neonatal outcomes.
- Conditions
- Maternal Obesity Complicating Pregnancy, Birth,or Puerperium, Gestational Diabetes Mellitus, Birthweight, Large for Gestational Age (LGA)
- Trial name
- NCT02750774
- Testing
- Low-glycemic index group, Standard Care Group
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Neonatal Morbidity and Mortality, Intrauterine Growth Disorders (IUGR and Macrosomia)
Analysis on the Health of Newborns in Three Hospitals, 2008-2024
The objective of this observational study is to analyze the factors associated with neonatal morbidity and mortality in three hospitals in Quito, Ecuador, from January 2008 to June 2024.
- Conditions
- Neonatal Morbidity and Mortality, Intrauterine Growth Disorders (IUGR and Macrosomia), Prematurity Complications, Neonatal Infections
- Trial name
- NCT06758622
- Where
- Ecuador
- Volunteers
- 40,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA
Hypoglycemia, Infant, Small for Gestational Age
Dextrose Gel Does Not Prevent Neonatal Hypoglycemia
This was a quasi-experimental pilot study comparing blood glucose values 30 minutes after feeding alone or feeding + dextrose gel in newborns at risk for transient neonatal hypoglycemia.
- Conditions
- Hypoglycemia, Infant, Small for Gestational Age, Premature Birth of Newborn, Fetal Macrosomia
- Trial name
- NCT02523222
- Testing
- 40% Dextrose gel
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Baylor College of Medicine
Fetal Macrosomia, Obesity Complicating Childbirth
Investigating the Relationship Between Triglycerides and Fetal Overgrowth in Gestational Diabetes
This is a prospective, observational study which examines the association between maternal triglycerides in the antepartum period and fetal overgrowth in pregnancies complicated by gestational diabetes.
- Conditions
- Fetal Macrosomia, Obesity Complicating Childbirth, Gestational Diabetes
- Trial name
- NCT06067685
- Testing
- Observation
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Macrosomia, Induction of Labor
Induction of Labor Versus Expectant Management of Large for Gestational Age/Macrosomic Babies at Term. A Multi-center Trial
The equipoise whether to Induce pregnant women with suspected large for gestational babies or suspected macrosomia babies at term pregnancy is not solved yet.
- Conditions
- Macrosomia, Induction of Labor, Expectant Management, Shoulder Dystocia
- Trial name
- IOLEMMT (NCT02315820)
- Testing
- Induction of labor group (Group I)
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Preterm Birth, Preeclampsia
The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health
The 'Standard of Care Plus' ('PLUS') model in the ROOT Study consists of analyzing select micronutrient and gene variants of pregnant females to construct trimester-specific and personalized nutrition and lifestyle…
- Conditions
- Preterm Birth, Preeclampsia, Gestational Diabetes Mellitus (GDM), Small for Gestational Age (SGA)
- Trial name
- ROOT (NCT07559773)
- Testing
- 'Standard of Care PLUS'
- Volunteers
- 500 people
- Sponsor
- GrowBaby Life Project
Obesity, Pregnancy
Weight Management for Improved Pregnancy Outcomes
This study will examine the safety and effectiveness of a dietary intervention in pregnant women. Women who are obese will be invited to participate.
- Trial name
- Healthy Moms (NCT00950235)
- Testing
- Weight Management, Usual Care
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Macrosomia
Accuracy of 5D LB Ultrasound in Prediction of Birth Weight in Macrosomic Babies : A Pilot Study
5D and 2D ultrasounds will be done for pregnant women with macrosomic fetuses to determine estimated fetal weight using hadlock formula. The accuracy of fetal weight obtained by ultrasound will be compared to actual birth weight.
- Trial name
- NCT02396667
- Testing
- 5D ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Gestational Diabetes, Other "Heavy-For-Dates" Infants
Pregnancy Outcomes and Maternal Insulin Sensitivity
The PROMIS study will focus on maternal insulin sensitivity thourghout pregnancy and postpartum in a moderate to high risk population (BMI ≥25 kg/m2) in developing adverse pregnancy outcomes.
- Conditions
- Gestational Diabetes, Other "Heavy-For-Dates" Infants, Small for Gestational Age Infant, Diabetes Mellitus, Type 2
- Trial name
- PROMIS (NCT04315545)
- Testing
- meal tolerance test
- Where
- 2 sites in Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Overweight, Pregnancy
A Low Glycemic Load Diet During Pregnancy in Overweight Women
This study will compare the effects of a low glycemic load versus standard diet for pregnancy on outcomes related to risk for obesity, diabetes, and heart disease in both mother and infant.
- Trial name
- NCT00364403
- Testing
- Low glycemic load, Low fat diet
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
Pregnancy Complications, Obesity
Metformin in Obese Non-diabetic Pregnant Women
Obesity is on the rise in all developed countries. Of particular concern is that more young people including children are being recognised as being overweight or obese.
- Trial name
- MOP (NCT01273584)
- Testing
- Metformin
- Where
- 3 sites in United Kingdom
- Volunteers
- 450 people
- Sponsor
- Epsom and St Helier University Hospitals NHS Trust
Overweight and Obesity, Weight Loss
PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus
The study is a single site parallel randomized controlled study. The study will be assessing the effect of a 10% pre-conceptional weight loss intervention vs a control group among healthy couples where the prospective mother is…
- Conditions
- Overweight and Obesity, Weight Loss, Pregnancy Related, Child Nutrition Sciences
- Trial name
- PREPARE CHILD (NCT05798494)
- Testing
- Weight loss intervention
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ulla Kampmann Opstrup
Gestational Diabetes, Pregnancy Complications
Timing of Ambulation and Infant Birth Weight in Gestational Diabetes
This is a randomized controlled trial to assess the effect of routine exercise counseling compared to the recommendation for postprandial ambulation on infant birthweight among pregnant people with gestational diabetes mellitus.
- Conditions
- Gestational Diabetes, Pregnancy Complications, Pregnancy in Diabetic, Fetal Macrosomia
- Trial name
- NCT06157684
- Testing
- Postprandial ambulation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Women and Infants Hospital of Rhode Island