Clinical trials: Laparoscopic Surgery, active
Dexmedetomidine, Total Intravenous Anesthesia
The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption
Opioids analgesic are the gold standard for intraoperative pain management. Their short- and long-term adverse effect motivate anesthesiologists to explore opioid sparing strategies.
- Conditions
- Dexmedetomidine, Total Intravenous Anesthesia, Remifentanil Consumption, Remifentanil
- Trial name
- DEXREM (NCT06684197)
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Laparoscopic Surgery, Visceral Pain, Postoperative
Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery
Visceral pain following laparoscopic surgery is frequently underestimated, yet it is associated with a range of adverse outcomes.
- Conditions
- Laparoscopic Surgery, Visceral Pain, Postoperative, Anrikefon, Patient-controlled Intravenous Analgesia
- Trial name
- NCT07525986
- Testing
- High-dose anrikefon, Medium-dose anrikefon, Low-dose anrikefon
- Where
- 4 sites in China
- Volunteers
- 140 people
- Sponsor
- Peking University First Hospital
Intravenous Lidocaine, Laparoscopic Surgery
Intravenous Lidocaine Plus Port-Site Ropivacaine for Recovery After Laparoscopic Surgery
This randomized controlled trial evaluates whether perioperative intravenous lidocaine infusion, combined with port-site ropivacaine infiltration, improves postoperative recovery after laparoscopic abdominal surgery.
- Conditions
- Intravenous Lidocaine, Laparoscopic Surgery, Post Operative Recovery, Local Anaesthetic Systemic Toxicity
- Trial name
- LivQor (NCT07414706)
- Testing
- Procedure/Standard care, ropivacaine, Lidocaine (intravenous infusion, perioperative)
- Where
- France
- Volunteers
- 182 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Appendectomy, Laparoscopic, Acute Appendicitis
Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children. Despite the widespread adoption of laparoscopic appendectomy, postoperative care still varies widely between institutions, with prolonged fasting, opioid-based…
- Conditions
- Appendectomy, Laparoscopic, Acute Appendicitis, Pediatric Surgery, ERAS
- Trial name
- NCT07643285
- Testing
- Comprehensive 20-Item Pediatric ERAS Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ahmet Burak Doğan, MD
Abdominal Laparoscopic Surgery
Application of the Maestro Surgical System for Surgical Assistance in Laparoscopic Abdominal Surgery
This study is designed to evaluate the application of the Maestro Robotic Platform for surgical assistance in laparoscopic abdominal surgery.
- Trial name
- MAESTRO (NCT07858929)
- Testing
- Any abdominal laparoscopic surgery with the usage of the Maestro Platform.
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Retrolaminar Block, TAP Block
Ultrasound Guided Retrolaminar Block Versus Transverse Abdominis Plane Block in Laparoscopic Upper Abdominal Surgeries
This study aims to compare and evaluate the safety and efficacy of ultrasound guided retrolaminar block versus transverse abdominis plane block in laparoscopic upper abdominal surgeries.
- Conditions
- Retrolaminar Block, TAP Block, Laparoscopic Abdominal Surgeries
- Trial name
- NCT07720817
- Testing
- Ultrasound-guided Retrolaminar Block group, Transverses Abdominis Plane (TAP) Block Group
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Laparoscopic Surgery, Post Operative Pain, Acute
Maneuvers to Reduce Laparoscopic Pain
Laparoscopic surgery has revolutionized surgical care by reducing morbidity and improving post operative recovery. Laparoscopic surgery involves the use of carbon dioxide for insufflation to achieve optimal visualization.
- Conditions
- Laparoscopic Surgery, Post Operative Pain, Acute, Pneumoperitoneum
- Trial name
- NCT07583433
- Testing
- Smoke Evacuation Group, Recruitment Breath Group, Control Group
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Patients Undergoing Major Laparoscopic Abdominal Surgery
Intrathecal Morphine for Postoperative Analgesia in Major Laparoscopic Abdominal Surgery, a IMPACT-Scope Trial
The goal of this clinical trial is to learn the clinical and cost effectiveness of intrathecal morphine (ITM) in addition to usual care as a postoperative pain relief strategy following major laparoscopic abdominal surgery…
- Trial name
- IMPACT-Scope (NCT06666985)
- Testing
- ITM + Usual Care
- Where
- China
- Volunteers
- 700 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Hysterectomy, Laparoscopic Surgery
Ureterolysis in Laparoscopic Total Hysterectomy: Routine Approach
This randomized controlled trial will compare routine bilateral ureterolysis with selective ureterolysis during total laparoscopic hysterectomy for benign gynecological conditions.
- Trial name
- ULTRA (NCT07774858)
- Testing
- Routine Ureterolysis, Selective Ureterolysis
- Where
- Egypt
- Volunteers
- 35,000 people
- Sponsor
- ClinAmygate
Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Increase
Assessment of Optic Sheat Diameter (ONSD) and Eyeball Transverse Diameter (ETD) Ratio Measurement From Ocular Ultrasound
The aim of this study is to evaluate the effects of different carbon dioxide gas insufflation pressures on the ultrasound-guided optic nerve sheath diameter in patients undergoing laparoscopic cholecystectomy and to determine the…
- Conditions
- Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Increase, Laparoscopic Cholecystectomy Surgery
- Trial name
- ONSD ETD (NCT07784361)
- Testing
- Low Pressure Group, High Pressure Group
- Volunteers
- 68 people
- Sponsor
- Gaziantep City Hospital
Pelvic Organ Prolapse (POP), Genital Prolapse
Safety and Performance of a Pelvic Floor Mesh Implant (LatGYNious)
The purpose of the clinical investigation is to verify that the investigational device (LatGYNious) is appropriate to significantly improve the pelvic organ prolapse in patients.
- Conditions
- Pelvic Organ Prolapse (POP), Genital Prolapse, Uterus Prolapse, Laparoscopic Surgery
- Trial name
- NCT07066761
- Testing
- Laparoscopic lateral suspension with surgical mesh (LatGYNious)
- Where
- 5 sites in Austria, Germany
- Volunteers
- 85 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Laparoscopic Gynecological Surgery
EEG and ANI Guided Anesthesia and Quality of Recovery
This study aims to assess whether electroencephalogram (EEG) and nociception level-guided anesthesia can improve quality of recovery after laparoscopic gynecological surgery compared with standard care.
- Trial name
- NCT05936671
- Testing
- EEG-and-ANI-guided anesthesia, standard anesthesia, Sevoflurane and remifentanil
- Where
- 2 sites in South Korea
- Volunteers
- 126 people
- Sponsor
- Gangnam Severance Hospital
Cholecystitis, Acute, Cholecystectomy, Laparoscopic
Implementation of RICA (ERAS) Guidelines in Grade II Acute Cholecystitis Undergoing Early Laparoscopic Cholecystectomy
Background Acute cholecystitis (sudden gallbladder inflammation, usually due to gallstones) is a highly frequent surgical emergency.
- Conditions
- Cholecystitis, Acute, Cholecystectomy, Laparoscopic, Enhanced Recovery After Surgery
- Trial name
- COLERICA II (NCT07695922)
- Testing
- RICA Perioperative Care Pathway
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Hospital d'Igualada
Postoperative Nausea and Vomiting (PONV), Enhanced Recovery After Surgery
Efficacy and Safety Between Tegileridine and Sufentanil in Laparoscopic Surgery Patients at High Risk of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) is one of the most common and distressing perioperative adverse events in patients undergoing laparoscopic surgery.1 Although laparoscopic procedures are minimally invasive, PONV can still…
- Conditions
- Postoperative Nausea and Vomiting (PONV), Enhanced Recovery After Surgery, Laparoscopic Surgery
- Trial name
- NCT07691086
- Testing
- analgesic drugs and methods
- Volunteers
- 800 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postoperative Analgesia, Transversus Abdominis Plane (TAP) Block
Transversalis Fascia Plane Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Children
This prospective clinical study aims to compare the postoperative analgesic efficacy of the ultrasound-guided transversalis fascia plane block (TFPB) and the transversus abdominis plane (TAP) block in pediatric patients…
- Conditions
- Postoperative Analgesia, Transversus Abdominis Plane (TAP) Block, Transversalis Fascia Plane Block, Pediatric Surgical Procedures
- Trial name
- NCT07242196
- Testing
- Postoperative analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Bowel Diseases, Inflammatory, Bowel Surgery
Use of Dexmedetomidine to Improve Pain Control and Recovery After Laparocopic-Assisted Bowel Surgery in Adults
This study is testing whether continuing a medication called dexmedetomidine after surgery can improve quality of recovery for adults undergoing laparoscopic-assisted bowel surgery.
- Conditions
- Bowel Diseases, Inflammatory, Bowel Surgery, Laparoscopic Abdominal Surgeries
- Trial name
- PODEX (NCT07434310)
- Testing
- Dexmedetomidine infusion
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Dr. Naveed Siddiqui
Laparoscopic Surgery, Laparoscopic Cholecystectomy
Pre-incisional Infiltration With Ropivacaine Plus Triamcinolone for Relieving Postoperative Pain After Laparoscopic Surgery
Incisional infiltration is the simplest, safest, and most effective anesthesia method for preventing incision pain after laparoscopic surgery, but even using long-acting local anesthetics, the effectiveness of postoperative…
- Conditions
- Laparoscopic Surgery, Laparoscopic Cholecystectomy, Appendectomy, Laparoscopic, Hernia Repair
- Trial name
- NCT07591233
- Testing
- Pre-incisional infiltration with ropivacaine plus triamcinolone, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tiantan Hospital
Laparoscopic Surgery, Laparoscopic Appendectomy
Pre-incisional Infiltration With Ropivacaine Plus Diprospan for Relieving Postoperative Pain After Laparoscopic Surgery
Incisional infiltration is the simplest, safest, and most effective anesthesia method for preventing incision pain after laparoscopic surgery, but even using long-acting local anesthetics, the effectiveness of postoperative…
- Conditions
- Laparoscopic Surgery, Laparoscopic Appendectomy, Laparoscopic Cholecystectomy, Laparoscopic Hernia Repair Surgery
- Trial name
- NCT07626463
- Testing
- Pre-incisional infiltration with ropivacaine and diprospan, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tiantan Hospital
Elderly Patients, Laparoscopic Surgery
Transnasal Microstream EtCO2 Reduces Hypoxemia During Emergence in Aged Post-Abdomen Surgery
This prospective, randomized controlled study aims to investigate whether transnasal microstream end-tidal carbon dioxide (EtCO₂) monitoring in the post-anesthesia care unit (PACU) reduces the incidence of postoperative hypoxemia…
- Conditions
- Elderly Patients, Laparoscopic Surgery, Postoperative Hypoxemia, Capnography
- Trial name
- NCT07652385
- Testing
- EtCO₂ Monitoring, Routine Monitoring
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Obesity, Bariatric Surgery
Eating Behavior, Nutritional Status and Appetite Hormones After Bariatric Surgery
This study aims to evaluate changes in eating behavior attitudes, nutritional status, and appetite-regulating hormonal parameters in individuals who have undergone Laparoscopic Sleeve Gastrectomy (LSG).
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Eating Behavior
- Trial name
- BCKYL-YDB (NCT07636239)
- Testing
- Anthropometric Measurements and Dietary Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Özlem ÖZPAK AKKUŞ