Clinical trials: Laparoscopic Roux-en-y Gastric Bypass
Anastomosis, Roux-en-Y, Surgical Operation With Anastomosis, Bypass or Graft
Comparison of Laparoscopic Traditional and Knotless Sutures
Background Excess weight and obesity is the fifth leading risk factor for global death. Bariatric surgery is considered as the only effective long-term treatment for morbid obesity.
- Trial name
- NCT02720718
- Testing
- Stratafix, Vicryl
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AZ St.-Dimpna Geel
Morbid Obesity, Postoperative Complications
Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic One Anastomosis Gastric Bypass
This study try to identify differences in cost, length of operation and results between two different bariatric surgical techniques, the laparoscopic Roux-en-Y gastric bypass and the Single anastomosis laparoscopic gastric…
- Conditions
- Morbid Obesity, Postoperative Complications, Weight Loss
- Trial name
- OAGB-vs-LRYGB (NCT02779322)
- Testing
- Minigastric bypass, Gastric bypass
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Puerta de Hierro University Hospital
Diabetes, Gastric Bypass
Glucose Metabolism in the Immediate and Short Term Follow up After Bariatric Surgery
MIDAS involves an assessment of glucose levels obtained before and after bariatric surgery. There are two different procedural tests involved; an oral glucose tolerance test (mixed meal) and a hyperglycemic clamp test.
- Trial name
- MIDAS (NCT00488423)
- Testing
- Mixed Meal Tolerance test, Hyperglycemic clamp
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The Cleveland Clinic
Pain, Obesity
Pain Relieving Efficacy of TAP Block in Patients After Laparoscopic Gastric Bypass.
The purpose of this study is to determine whether injection of bupivacaine into the TAP is effective in the treatment of post operative pain after laparoscopic gastric bypass
- Conditions
- Pain, Obesity, Surgery, Neuromuscular Inhibition
- Trial name
- NCT01308554
- Testing
- Marcaine
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Funch-Jensen, Peter, M.D., D.M.Sc.
Diabetes, Interleukins
Randomized Controlled Trial of Laparoscopic Gastric Bypass Plus Omentectomy Versus Laparoscopic Gastric Bypass Alone in Improving Diabetic Indices
To see if removing the omentum in addition to a gastric bypass improves diabetes is better than just a gastric bypass.
- Conditions
- Diabetes, Interleukins, Cytokines
- Trial name
- NCT00552942
- Testing
- laparoscopic gastric bypass plus omentectomy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Legacy Health System
Pain, Postoperative, Postoperative Pain
Intraperitoneal Aerosolized Delivery of a Local Anesthetic for Post Operative Pain Management. A Double Blind, Randomised Controlled Clinical Trial.
The purpose of this study is to determine the effectiveness of aerosolized pain medication (.5% bupivicaine) delivered into the peritoneal cavity after laparoscopic gastric bypass surgery.
- Conditions
- Pain, Postoperative, Postoperative Pain, Abdominal Pain, Obesity
- Trial name
- NCT00286286
- Testing
- Intraperitoneal Aerosolization System, IntraMyst
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Northgate Technologies
Type 2 Diabetes
Mechanisms of Diabetes Relapse After Bariatric Surgery
The objective of this study is to investigate the different mechanisms by which Gastric Bypass (GBP), laparoscopic adjustable gastric banding (LAGB) and vertical sleeve gastrectomy (VSG) affect glucose control.
- Trial name
- LAF26 (NCT01516320)
- Testing
- Roux-en-Y Gastric Bypass, Laparoscopic adjustable gastric banding, Vertical Sleeve Gastrectomy
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Blandine Laferrere
Diabetes Mellitus, Type 2
Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus With Body Mass Index (BMI) < 35
The aim of this study is to evaluate the effect of Roux-en-y gastric bypass (RYGB) in controlling diabetes in subjects with mild obesity (BMI 26-35).
- Trial name
- NCT00999050
- Testing
- Gastric bypass for diabetic patients <35 BMI
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Type 2 Diabetes, Obesity
Intestinal Remodeling And Reprogramming of Glucose Metabolism Following Laparoscopic Roux-en-Y Gastric Bypass
The purpose of this study is to investigate small intestinal remodeling and reprogramming of glucose metabolism in patients with Type 2 Diabetes Mellitus (T2DM) who undergo laparoscopic Roux-en-Y Gastric Bypass (RYGB).
- Trial name
- NCT02288351
- Testing
- Mix Nutrient Meal, labs, Biopsy
- Sponsor
- Duke University
Obesity, Metabolic Disease
Conventional Vs Tailored Limb Lengths in Laparoscopic Roux-en Y Gastric Bypass Surgery
The study aims to investigate whether tailoring limb lengths based on the 1/3rd and 2/3rd concept improves clinical outcomes in Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) surgery compared to conventional limb lengths.
- Conditions
- Obesity, Metabolic Disease, Bariatric Surgery Candidate, Metabolic Surgery
- Trial name
- TAILO-R-YGB (NCT06756789)
- Testing
- Laparoscopic Roux-en Y Gastric bypass (RYGB)- Conventional approach, Laparoscopic Roux-en Y Gastric bypass (RYGB)- Tailored approach
- Where
- India
- Volunteers
- 40 people
- Sponsor
- GEM Hospital & Research Center
Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass
Laparoscopic Revision of Jejunoileal Bypass to Gastric Bypass
This study objectives are the following. To describe the updated clinical presentation, indications, and multidisciplinary medical management of patients with a failed and/or complicated jejunoileal bypass (JIB).
- Conditions
- Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass, Nutritional Complications After Jejunoileal Bypass, Obesity Recidivism
- Trial name
- JIB-to-RYGB (NCT01040533)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Postoperative Complications, Operative Time
Eliminating Learning Curve Related Morbidity in Fast Track Laparoscopic Roux-en-Y Gastric Bypass
Background: Laparoscopic Roux en Y gastric bypass (LRYGB) is associated with a significant learning curve. We report the results of a systematic training programme from a high volume bariatric center measuring the outcome by…
- Conditions
- Postoperative Complications, Operative Time, Surgical Volume
- Trial name
- NCT01257789
- Testing
- laparoscopic gastric bypass
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Private Hospital Moelholm
Type 2 Diabetes Mellitus, Obesity
Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes
There is substantial clinical evidence regarding the safety and efficacy of currently practiced bariatric surgical techniques to improve metabolic control and/or resolve type 2 diabetes (T2DM) in clinically severe obese patients…
- Trial name
- SLIMM-T2D (NCT01073020)
- Testing
- Allergan Adjustable Gastric Band Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group, Roux-en-Y Gastric Bypass (RYGB) Surgery
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- Joslin Diabetes Center
Laparoscopic Sleeve Gastrectomy, Sleeve Gastrectomy
A Retrospective Multicenter Comparison of Laparoscopic and Robotic-Assisted Roux-en-Y Gastrectomy
The prevalence of obesity has tripled in the last 50 years with presently about 1.7 billion of the world population aged 18 years and over either overweight or obese.1 In the US alone, 35% of the population is obese.2 Although…
- Trial name
- NCT05224791
- Testing
- Roux-en-Y Gastric Bypass, Sleeve Gastrectomy
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Methodist Health System
Bone Loss, Bone Density
Bone Loss After Laparoscopic Roux-en-Y Gastric Bypass
The objective of this study is to assess changes bone mineral density and bone metabolism after laparoscopic Roux-en-Y gastric bypass surgery.
- Conditions
- Bone Loss, Bone Density, Gastric Bypass, Bariatric Surgery
- Trial name
- NCT00975013
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Gundersen Lutheran Medical Foundation
Benchmark, Bariatric Surgery
Defining Benchmarks in Bariatric Surgery
Aim: To define benchmark outcomes in minimally-invasive primary bariatric surgery. Design: Multicenter retrospective cohort study.
- Conditions
- Benchmark, Bariatric Surgery, Roux-en-y Gastric Bypass, Sleeve Gastrectomy
- Trial name
- BBenchmarks (NCT03440138)
- Testing
- bariatric surgery (RYGB or SG)
- Where
- Switzerland
- Volunteers
- 5,741 people
- Sponsor
- Marco Bueter
Obesity
Randomized Trial Comparing Laparoscopic Roux-en-y Gastric Bypass to Micro-laparoscopic Roux-en-y Gastric Bypass
Background Laparoscopy is the preferred surgical approach for a number of different diseases as it allows for diagnosis and treatment in the setting of a safe and feasible method offering enhanced cosmesis.
- Trial name
- NCT01183273
- Testing
- Microlaparoscopic gastric bypass, Laparoscopic Surgery
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Suzanne J. Rose
Obesity, Morbid
Comparing a Randomised Controlled Intervention With Observational Data.
Comparison of participants in a randomised controlled trial (RCT) with observational data from patients operated in Sweden during the same period of time.
- Trial name
- NCT02763501
- Testing
- closure of mesenteric defects, non-closure of mesenteric defects
- Volunteers
- 10,992 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Reflux Disease, Gastro-Esophageal, Vomiting, Postoperative
Antireflux Suture In One Anastomsis Gastric Bypass
To prevent refulx symptoms in a type of bariatric surgery, a suture is taken.there is no enough evidence in support of or against the suture.
- Trial name
- NCT07148492
- Testing
- Antireflux suture, No Antireflux suture
- Where
- Pakistan
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Khyber Teaching Hospital
Steatohepatitis, Morbid Obesity
Transoral Endoscopic Liver Biopsy During Laparoscopic Gastric Bypass
This research is being done to evaluate the ability to obtain a liver sample using upper endoscopy rather than through a laparoscopic procedure.
- Trial name
- NCT00512512
- Testing
- Transoral Endoscopic Liver Biopsy
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University