Clinical trials: Laparoscopic Hysterectomy
Cervical Cancer
German-funded Laparoscopic Approach to Cervical Cancer
The G-LACC trial is a prospective, interventional, multicenter, open-label, randomized and controlled non-inferiority operative trial.
- Trial name
- G-LACC (NCT06489795)
- Testing
- Laparoscopic or robot-assisted radical/simple hysterectomy, Abdominal radical/simple hysterectomy
- Where
- 14 sites in Germany
- Volunteers
- 756 people
- Sponsor
- Hannover Medical School
Hysterectomy
vNOTES vs Laparoscopic Hysterectomy: Randomized Trial on Pain and Recovery"
This study is a prospective, randomized controlled trial comparing two different minimally invasive hysterectomy techniques: vaginal natural orifice transluminal endoscopic surgery (vNOTES) and conventional total laparoscopic…
- Trial name
- VNOTES-TLH (NCT07306507)
- Testing
- vNOTES Hysterectomy, Total Laparoscopic Hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Musculoskeletal Diseases or Conditions
Ergonomic Benefits From Robotically Assisted Laparoscopy for Hysterectomies and Other Indications
This is a prospective, single-center, observational clinical trial at the Department of Women's Health of the University Hospital Tübingen.
- Trial name
- ERCON (NCT06109753)
- Testing
- Robotically Assisted Laparoscopic Surgery, Conventional Laparoscopic Surgery
- Where
- Germany
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Intracranial Pressure Increase
Evaluation of the Effect of Trendelenburg Position Duration on Intracranial Pressure
The Lloyd Davies position is a position used in laparoscopic hysterectomies where the head is lowered 45 degrees and the legs are bent from the knee area.It is a version of the Trendelenburg position.
- Trial name
- NCT06048900
- Testing
- ultrasound guided optic nerve sheath diameter measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Dilek Cetinkaya
Hysterectomy, Vaginal
Hysterectomy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery Versus or Laparoscopic Hysterectomy
In France, there are approximately 62,000 hysterectomies per year, 70% of which are benign. It is the most frequent surgical procedure in gynecology.
- Trial name
- vNOTESHC (NCT05884658)
- Testing
- vNOTES : natural vaginal orifice transluminal endoscopic system for hysterectomies, laparoscopic hysterectomy
- Where
- 6 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Patients Undergoing Total Laparoscopic Hysterectomy
Effect of Intraoperative Nociception Control Based on Analgesia Nociception Index (ANI) Monitoring on Stress Response During Total Laparoscopic Hysterectomy
The "Analgesia Nociception Index" (ANI; MetroDoloris Medical Systems, Lille, France), derived from an electrocardiogram (ECG) trace, has been proposed as a noninvasive guide to analgesia.
- Trial name
- NCT04343638
- Testing
- conventional nociception control, ANI monitor guided nociception control
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Yonsei University
Postoperative Pain
Clinical Effectiveness and Safety of Intraoperative Methadone in Patients Undergoing Laparoscopic Hysterectomy
The role of a single-dose of intraoperative methadone on postoperative pain and opioid consumption in patients undergoing hysterectomy remains scarcely explored.
- Trial name
- NCT03908060
- Testing
- Methadone, Morphine
- Where
- Denmark
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Surgical Wound Dehiscence
Vaginal Cuff Dehiscence at Total Laparoscopic Hysterectomy
The aim of this study is to assess a major complication of total laparoscopic hysterectomy, vaginal dehiscence, with two different colpotomy techniques.
- Trial name
- NCT02879487
- Testing
- Monopolar needle electrode
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Benign Gynecological Disease
Laparoscopic vs Vaginal Hysterectomy for Benign Gynaecological Disease
This study is designed to compare laparoscopic and vaginal hysterectomy in women with benign gynaecological disease in Ain Shams University Maternity Hospital.
- Trial name
- NCT03692832
- Testing
- LH, VH
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Inflammatory Response, Pain, Postoperative
Dexamethasone and Robotic-assisted Hysterectomy
Robotic-assisted hysterectomy is an alternative to laparoscopic surgery as part of a minimal invasive regimen. Several treatment strategies are followed to improve the overall outcome and minimize surgical stress.
- Conditions
- Inflammatory Response, Pain, Postoperative, Nausea, Postoperative, Incontinence
- Trial name
- NCT04762381
- Testing
- Dexamethasone phosphate
- Where
- Denmark
- Volunteers
- 109 people
- Sponsor
- Herning Hospital
Uterine Myoma, Uterine Adenomyosis
Study of Different Pain Scores in Single-Port Access (SPA) Laparoscopic Hysterectomy Versus Conventional Laparoscopic Hysterectomy
Purpose: The attempt to further reduce the operative trauma in laparoscopic hysterectomy led in new technique such as Single-Port Access (SPA) laparoscopic surgery.
- Trial name
- NCT01064128
- Testing
- conventional laparoscopic hysterectomy, SPA laparoscopic hysterectomy
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Gynecologic Surgery
Safety, Efficacy and Operability of Using the New Tissue Containment System During Laprascopic Hysterectomy
The study is designed to evaluate the safety, operability and efficacy of performing the new tissue containment system during laparoscopic hysterectomy. Pre- and perimenopausal women undergoing laparoscopic hysterectomy.
- Trial name
- NCT04423172
- Testing
- the new tissue containment system
- Volunteers
- 120 people
- Sponsor
- Jing Liang
Post Operative Pain, Gynecologic Cancer
Pilot: Intraoperative TAP Block and Post-operative Pain Control for Minimally Invasive Hysterectomy for Endometrial Cancer
Modern postoperative pain management aims to optimizing pain relief while minimizing opiate usage. While opiates are effective for pain relief, they result in common adverse effects such as nausea, constipation, and urinary…
- Trial name
- NCT05763667
- Testing
- Liposomal bupivacaine, Bupivacain
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Tufts Medical Center
Bladder Injury, Ureter Injury
Comparison of Standard Cystoscopy With Carbon Dioxide Cystoscopy
For the evaluation of the lower urinary tract after laparoscopic hysterectomy, routine standard saline cystoscopy and carbon dioxide cystoscopy will be compared.
- Conditions
- Bladder Injury, Ureter Injury, Surgical Injury, Complication of Surgical Procedure
- Trial name
- NCT06278753
- Testing
- carbon dioxide cystoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 540 people
- Sponsor
- Tepecik Training and Research Hospital
Hysterectomy, Laparoscopy
Abdominal Versus Vaginal Bisection in Laparoscopic Hysterectomy
Large uteri present a challenge during Total lap.hysterectomy and its extraction is another challenge. This study addressees and compare 2 methods of retrieval of large uteri
- Conditions
- Hysterectomy, Laparoscopy, Uterine Bisection, Large Uteri
- Trial name
- TLH-Bisection (NCT04904822)
- Testing
- Vaginal bisection, Abdominal bisection
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Tanta University
Intertransverse Process Block, Mtapa Block
Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Hysterectomy
This randomized clinical trial aims to evaluate and compare the analgesicefficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients…
- Conditions
- Intertransverse Process Block, Mtapa Block, Laparoscopic Hysterectomy, Postoperative Pain
- Trial name
- NCT07599787
- Testing
- Intertransverse Process Block, M-TAPA Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Anxiety, Pain, Postoperative
Music Therapy Pathway in Patients Undergoing Total Laparoscopic Hysterectomy
Music therapy is a non-invasive, safe, and inexpensive intervention that can be easily and successfully delivered. it has been shown that music therapy might reduce the postoperative pain in patients undergoing cesarean section…
- Trial name
- NCT04243967
- Testing
- Music therapy, Control
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Hysterectomy
ESP Block VS TAP in Laparoscopic Hysterectomy
The purpose of this study is to compare the difference between two different pain control methods in patients who will be having a hysterectomy surgery.
- Trial name
- NCT04003987
- Testing
- Liposomal bupivacaine, bupivacaine, 0.125%
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Indiana University
Total Laparoscopic Hysterectomy With Myoma Screw
Myoma Screw in Manipulation of Large Uterus in Total Laparoscopic Hysterectomy
To compare between myoma screw and uterine manipulator in manipulation of large uterus in total laparoscopic hysterectomy
- Trial name
- NCT06976905
- Testing
- Total laparoscopic hysterectomy
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Laparoscopic Surgery, Intraocular Pressure
The Effect of the Steep Trendelenburg Position on Intraocular Pressure
A total of 50 patients aged between 18-60 years, classified as American Society of Anesthesiologists (ASA) I-II, undergoing elective total laparoscopic hysterectomy in the steep trendelenburg position (STP) will be included in…
- Trial name
- NCT06440642
- Testing
- tonopen
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital