Clinical trials: Laparoscopic Gastrectomy
Early Gastric Cancer, Adenocarcinoma of the Stomach
SPADE Clinical Trial.
Purpose: This multicenter, prospective, single-arm phase 2 clinical trial aims to evaluate the safety, feasibility, and clinical outcomes of the SPADE operation (Spade-Shaped Anastomosis) in patients undergoing laparoscopic or…
- Conditions
- Early Gastric Cancer, Adenocarcinoma of the Stomach, Proximal Gastric Cancer, SPADE Operation
- Trial name
- SPADE (NCT07892183)
- Testing
- Spade-Shaped Anastomosis after Laparoscopic or Robotic Proximal Gastrectomy Using Double Suture Anchoring between the Posterior Wall of the Esophagus and the Anterior Wall of the Stomac
- Where
- South Korea
- Volunteers
- 159 people
- Sponsor
- National Cancer Center, Korea
Laparoscopic Sleeve Gastrectomy
Comparison of Staple Line Suturing in Laparoscopic Sleeve Gastrectomy
Sleeve gastrectomy (SG) involves the creation of small gastric reservoir based on lesser curvature of the stomach, which is fashioned by a longitudinal gastrectomy that preserves the antrum and pylorus together with its vagal…
- Trial name
- NCT04323696
- Testing
- Staple line suturing reinforcement methods - Plication and Over-sewing
- Sponsor
- Universiti Putra Malaysia
Laparoscopic Sleeve Gastrectomy
Efficacy of Ultrasound-guided External Oblique Intercostal Plane Block Versus Port-site Local Anesthetic Infiltration for Postoperative Analgesia and Pulmonary Function After Laparoscopic Sleeve Gastrectomy
Obesity poses severe global health risks and induces complex cardiorespiratory alterations, making perioperative care critical. For patients with morbid obesity, Laparoscopic Sleeve Gastrectomy (LSG) is the most effective…
- Trial name
- NCT07816055
- Testing
- Port-Site Local Anesthetic Infiltration, External Oblique Intercostal Block
- Volunteers
- 54 people
- Sponsor
- Assiut University
Obesity, Bariatric Surgery
Comparison of Epidural and Intravenous Analgesia in Laparoscopic Sleeve Gastrectomy Patients
This retrospective observational study aimed to compare the effects of epidural analgesia and intravenous analgesia on early postoperative pulmonary function in patients undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy
- Trial name
- EAvs IV in LSG (NCT07712224)
- Testing
- Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution), Intravenous analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Obesity, Bariatric Surgery
Eating Behavior, Nutritional Status and Appetite Hormones After Bariatric Surgery
This study aims to evaluate changes in eating behavior attitudes, nutritional status, and appetite-regulating hormonal parameters in individuals who have undergone Laparoscopic Sleeve Gastrectomy (LSG).
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Eating Behavior
- Trial name
- BCKYL-YDB (NCT07636239)
- Testing
- Anthropometric Measurements and Dietary Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Özlem ÖZPAK AKKUŞ
Ondansetron, Laparoscopic
Intravenous Versus Perineural Ondansetron for Laparoscopic Sleeve Gastrectomy
This prospective randomized non-inferiority study will be conducted to compare the analgesic anti-emetic effects of intravenous ondansetron versus perineural ondansetron in patients undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Ondansetron, Laparoscopic, Gastrectomy
- Trial name
- NCT06810882
- Testing
- Perineural ondansetron, Intravenous ondansetron
- Where
- Egypt
- Volunteers
- 482 people
- Sponsor
- Tanta University
Ultrasound, External Oblique Intercostal Plane Block
Ultrasound-Guided External Oblique Intercostal Plane Block Versus Subcostal Transversus Abdominis Plane Block For Perioperative Analgesia in Laparoscopic Sleeve Gastrectomy
This study aims to compare the analgesic efficacy, duration of analgesia, and overall opioid consumption between the external oblique intercostal plane (EOIP) block and subcostal transversus abdominis plane (TAP) block in…
- Conditions
- Ultrasound, External Oblique Intercostal Plane Block, Subcostal Transversus Abdominis Plane Block, Perioperative Analgesia
- Trial name
- NCT07366138
- Testing
- External oblique intercostal plane block, Subcostal transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Laparoscopic Sleeve Gastrectomy (LSG), Thoracic Lung Resection Procedure
A Study of ECHELON 3000 (Next Generation Powered Stapler) in General Abdominal and Thoracic Lung Resection Procedures
The purpose of this study is to assess the safety and performance of the ECHELON 3000 Stapler (next generation powered stapler) and reload system in participants undergoing laparoscopic sleeve gastrectomy or lung resection…
- Trial name
- NCT05519215
- Testing
- ECHELON 3000 Stapler
- Where
- 8 sites in United States
- Volunteers
- 244 people
- Sponsor
- Ethicon Endo-Surgery
Laparoscopic Sleeve Gastrectomy (LSG), Erector Spinae Plane Block
Comparing Perioperative Analgesia After Ultrasound Guided Bilateral Erector Spinae Plane Block and Thoracic Paravertebral Block in Laparoscopic Sleeve Gastrectomy Patients
The aim of this study is to compare the efficacy of ultrasound-guided bilateral erector spinae plane block and thoracic paravertebral block on perioperative analgesic control for 24 hours postoperative and fast recovery of…
- Conditions
- Laparoscopic Sleeve Gastrectomy (LSG), Erector Spinae Plane Block, Thoracic Paravertebral Block
- Trial name
- NCT06798103
- Testing
- Erector Spinae Plane Block, Thoracic paravertebral block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Pain, Postoperative, Obesity, Morbid
Effect of Bilateral Rectointercostal Fascial Plane Block on Postoperative Pain After Laparoscopic Sleeve Gastrectomy
This randomized controlled study aims to evaluate the effectiveness of the bilateral rectointercostal fascial plane (RIB) block for postoperative pain management in patients undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Pain, Postoperative, Obesity, Morbid, Laparoscopic Sleeve Gastrectomy (LSG), Opioid Use
- Trial name
- NCT07253610
- Testing
- Bilateral Rectointercostal Fascial Plane Block, Intravenous Patient-Controlled Analgesia (IV PCA) with Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Samsun University
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Postoperative Nausea and Vomiting, Postoperative Pain After Laparoscopic Sleeve Gastrectomy
Paragastric Block for Pain and PONV in Sleeve Gastrectomy
This single-center, prospective, randomized, double-blind controlled trial aims to evaluate the effects of intraoperative paragastric block (PGBLOCK) on early postoperative visceral pain, postoperative nausea and vomiting (PONV)…
- Trial name
- BLOCK-SG (NCT07274215)
- Testing
- Bupivacaine 0.5%, Isotonic Saline (0.9% NaCl)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Umraniye Education and Research Hospital
Gastric Adenocarcinoma, Laparoscopic Gastrectomy
Feasibility of Enhanced Recovery After Surgery Without Prophylactic Abdominal Drainage Tubes After Laparoscopic Distal Gastrectomy For Gastric Cancer
This study aims to compare the effects of using prophylactic abdominal drainage tubes during Enhanced Recovery After Surgery (ERAS) in patients undergoing Laparoscopic Distal Gastrectomy (LDG) for gastric cancer through a…
- Conditions
- Gastric Adenocarcinoma, Laparoscopic Gastrectomy, Complications
- Trial name
- NCT07029269
- Testing
- ERAS-tubeless group, ERAS-tube group
- Where
- 6 sites in China
- Volunteers
- 454 people
- Sponsor
- Zuoyi Jiao
Post Operative Pain, Laparoscopic Sleeve Gastrectomy
Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy
This will be a prospective, obesity-registry based, single-blind randomized controlled trial with a 1:1 allocation ratio. Specific inclusion criteria are all patients eligible to undergo a Laparoscopic sleeve gastrectomy (LSG)…
- Conditions
- Post Operative Pain, Laparoscopic Sleeve Gastrectomy, Robotic Sleeve Gastrectomy, Obesity
- Trial name
- EARLY (NCT06425016)
- Testing
- Laparoscopic Sleeve Gastrectomy (LSG), Robotic Sleeve Gastrectomy (RSG)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Ricard Corcelles
Gastric Cancer (Diagnosis), Gastric Cancer Patient
Peri-habilitation for Patients With Gastric Cancer
This study aims to evaluate the clinical applicability of a peri-habilitation program in patients with gastric cancer by applying nutritional intervention for approximately two weeks before surgery and a combined exercise and…
- Conditions
- Gastric Cancer (Diagnosis), Gastric Cancer Patient, Gastric Cancer Patients Undergoing Gastrectomy, Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy
- Trial name
- NCT07201857
- Testing
- nutrition education plus active supplement, Exercise
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Korea University Anam Hospital
Morbid Obesity, Surgical Management by Laparoscopic Sleeve Gastrectomy
Kinematics of Obese Patients Perambulation
The aim of this study is to evaluate the consequences of sleeve gastrectomy on functional parameters of patients perambulation.
- Trial name
- MARCHOBESE (NCT01774682)
- Testing
- 6-minute walk test
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Obesity and Obesity-related Medical Conditions, Laparoscopic Sleeve Gastrectomy
Postoperative Gastroesophageal Reflux Symptoms After Laparoscopic Sleeve Gastrectomy Based on the Presence of Preoperative Symptoms
This study aims to investigate the patterns of reflux symptoms after laparoscopic sleeve gastrectomy based on the presence or absence of preoperative gastroesophageal reflux symptoms.
- Conditions
- Obesity and Obesity-related Medical Conditions, Laparoscopic Sleeve Gastrectomy, Gastro-oesophageal Reflux
- Trial name
- NCT06835933
- Testing
- Laparoscopic sleeve gastrectomy
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Korea University Anam Hospital
Gastric Cancer (GC), Gastrectomy
Feasibility and Safety of Laparoscopic Purse-string Suture Clamp and Multi-functional Seal Cap for Totally Laparoscopic Radical Total Gastrectomy
Currently, there are three main methods for endoscopic esophagojejunostomy: circular, linear, and hand-sewn anastomosis, but no universally accepted optimal approach has been established.
- Conditions
- Gastric Cancer (GC), Gastrectomy, Anastomosis, Roux-en-Y, Laparoscopic
- Trial name
- NCT07117812
- Testing
- Laparoscopic purse-string forceps and multifunctional sealing ring
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Gastric Adenocarcinoma Patients, Who Are Scheduled for Laparoscopic Radical Gastrectomy
Comparison of Safety and Clinical Effects of Straight and Articulated Instruments (ArtiSential) in Laparoscopic Gastrectomy for Gastric Cancer Patients, a Prospective Randomized Study
In patients with gastric cancer, gastrectomy can be performed via laparoscopic/robotic or open surgery. It is crucial to completely remove the tumor along with an adequate extent of lymph node dissection.
- Trial name
- NCT07100431
- Testing
- Articulating (experimental group), Control (control group)
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Gangnam Severance Hospital
Gastrectomy for Gastric Cancer, Robotic Surgical Procedures
Assessment of Robotic Versus Laparoscopic Gastrectomy for GC Patients With Intraoperative Technical Complexity
While robotic gastrectomy (RG) is increasingly used in gastric cancer surgery, its potential advantages over laparoscopic gastrectomy (LG) in Intraoperative technical complexity (ITC) cases remain debated.
- Conditions
- Gastrectomy for Gastric Cancer, Robotic Surgical Procedures, Laparoscopic Surgical Procedures
- Trial name
- NCT06752538
- Where
- China
- Volunteers
- 3,534 people
- Sponsor
- Fujian Medical University