Clinical trials: Language Development Disorders
Stuttering/ Developmental
The Effect of the Non-invasive Brain Stimulation on the Speech Fluency Enhancement
The aim of this study is to determine the effectiveness of concurrent transcranial direct current stimulation (tDCS) and fluency training in adults with developmental stuttering.
- Trial name
- NCT03990168
- Testing
- Anodal tDCS, fluency intervention/ Delayed Auditory Feedback
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Iran University of Medical Sciences
Autism Spectrum Disorders
A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism
Background: Some children with autism spectrum disorders (ASD) do not have normal sleep cycles. Some of these children spend very little time in the rapid eye movement (REM) stage of sleep.
- Trial name
- NCT01887132
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Mental Health (NIMH)
Developmental Stuttering
Effectiveness of Digital Manipulation of Thyroid Cartilage and Fluency Shaping Therapy for the Management of Stuttering in Adult
This study was conducted to determine the effectiveness of digital manipulation of thyroid cartilage for the management of stuttering in adult.There were three groups,Group A received Digital Manipulation of Thyroid cartilage…
- Trial name
- NCT03628755
- Testing
- Digital Manipulation of Thyroid cartilage, Fluency Shaping Therapy, combination Group
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Isra University
Developmental Language Disorder, Speech Sound Disorder
A Framework For Linking Sequential Pattern Rules in DLD: Perception in Adults
This broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning.
- Conditions
- Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
- Trial name
- NCT04996472
- Testing
- Sensitivity to phonological rules: Adults, Sensitivity to semantic category cues: Adults
- Where
- 2 sites in United States
- Volunteers
- 933 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Autism Spectrum Disorder
Combination Treatment for Augmenting Language in Children With ASD
The study will consist of two main elements: the enrollment of 72 children aged 6-11 years with ASD and low language competency to receive a thrice-weekly one hour language intervention for 12 weeks; and, beginning at the same…
- Trial name
- PIII (NCT02574741)
- Testing
- Behavioral Therapy, Aripiprazole
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of California, Los Angeles
Asperger's Syndrome, Dyslexia
My Scrivener® - Measuring Effectiveness and Dose Response in Children
This study will assess whether a computer haptic peripheral device programmed to provide repetitive motion training is as effective as the same repetitive motion training provided by a human being.
- Conditions
- Asperger's Syndrome, Dyslexia, Cerebral Palsy, Attention Deficit Disorder
- Trial name
- NCT00919906
- Testing
- My Scrivener(R)
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Obslap Research LLC
Autism Spectrum Disorder, Depression - Major Depressive Disorder
Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models
This study investigates whether AI-driven analysis of speech can accurately predict clinical diagnoses and assess risk for various mental or behavioral health conditions, including attention-deficit/hyperactivity disorder (ADHD)…
- Conditions
- Autism Spectrum Disorder, Depression - Major Depressive Disorder, Anxiety, Generalized, Bipolar Disorder (BD)
- Trial name
- MINDAIM (NCT06792175)
- Testing
- Solicue Machine Learning Models, Mercuria Machine Learning Models
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Psyrin Inc.
Developmental Dyslexia
V5/MT Stimulation on Reading and Reading-related Measures in Developmental Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial direct current stimulation…
- Trial name
- NCT05972200
- Testing
- Active HD-tDCS over V5/MT, Active HD-tDCS over V1
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Language Development Disorders, Down Syndrome
Strategies for Teaching Verbs
This study is designed to evaluate whether children with Down syndrome and children with typical development exhibit different levels of accuracy demonstrating novel verbs taught under three conditions: semantic cues (perform…
- Conditions
- Language Development Disorders, Down Syndrome, Child Language
- Trial name
- NCT03441685
- Testing
- Semantic cues (perform action), syntactic cues (sentence frame), or combined semantic and syntactic cues
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Autism Spectrum Disorder, Autism Spectrum Disorder With Absence of Functional Language
Aut-CARE Intervention to Improve Cognitive and Emotional Functioning in Young Adults on the Autism Spectrum
Currently, many autistic youths struggle to adapt to academic programs or the workforce, often turning to third-sector organizations such as specialized associations and foundations.
- Trial name
- Aut-CARE (NCT07041502)
- Testing
- Aut-CARE
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Language Delay, Language; Developmental Disorder, Expressive
Intranasal Inhalations of M2 Macrophage Soluble Factors in Children With Developmental Speech Disorders
The investigators have designed an innovative proof-of-concept trial designed to provide data as to whether the speech difficulties in children with developmental dysphasia (DD) are improved with intranasal inhalations of…
- Conditions
- Language Delay, Language; Developmental Disorder, Expressive, Language; Developmental Disorder, Receptive, Autism Spectrum Disorder
- Trial name
- NCT04689282
- Testing
- Bioactive Factors, Produced by M2 Type Macrophages (M2-BFs).
- Where
- Russia
- Volunteers
- 14 people
- Sponsor
- Russian Academy of Medical Sciences
Deafness, Bilateral
Parent-Child Early Approaches to Raising Language Skills (PEARLS) Intervention
The purpose of this research study is to develop and evaluate a parent training program, which aims to improve language. The study is being conducted to see if teaching parents positive parenting techniques and behavior…
- Trial name
- PEARLS (NCT03260062)
- Testing
- Parent-Child Early Approaches to Raising Language Skills, Standard Care Speech therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Miami
Cerebral Palsy Children, Children With Traumatic Brain Injury
Cerebrolysin Neural Repair Therapy in Children With Traumatic Brain Injury and Cerebral Palsy
Cerebral palsy (CP) is the most frequent cause of motor handicap among children. The economic burden of CP in USA includes $1.18 billion in direct medical costs, $1.05 billion in direct non-medical costs, and an additional $9.24…
- Conditions
- Cerebral Palsy Children, Children With Traumatic Brain Injury, Mental Handicap, Delayed Speech Development
- Trial name
- NCT02116348
- Testing
- Cerebrolysin (Nerve growth factor)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Autism Spectrum Disorder
Tool for Evaluating the Effectiveness of the DENVER Protocol
Early remediation of the communicative and social difficulties of children with autism spectrum disorders (ASD) is central. However, from the age of 6-8 months, children with ASD show a lack of attention to social stimuli such as…
- Trial name
- FACECOM (NCT06253793)
- Where
- 3 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Autism Spectrum Disorder, Developmental Language Disorder
Efficacy of a Pragmatic Intervention to Improve Adaptation to Context and Interlocutor
Patients with Developmental Language Disorder (DLD) or Autism Spectrum Disorder (ASD) have communicational difficulties to adapt their language to context and to interlocutors.
- Trial name
- NCT05127863
- Testing
- social communication intervention (pragmatic)
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Université Catholique de Louvain
Dyslexia, Developmental
Poly-unsaturated Fatty Acids and Developmental Dyslexia
Poly-unsaturated fatty acids (PUFAs) represent a component of lipids that covers a relevant role in human diet and biological functions such as provision of energy, functionality of cell membranes and tissue metabolism.
- Trial name
- NCT04287530
- Testing
- Poly-unsaturated fatty acids supplementation, Neuropsychological intervention
- Where
- 2 sites in Italy
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Developmental Language Disorder and Language Impairment, Anxiety Disorders and Symptoms
Reducing Anxiety Problems Among Children Indicated to Have Developmental Language Disorder
This study aims to pilot a world-first intervention, a mental health intervention augmented for children indicated with developmental language disorder (DLD).
- Trial name
- RAP-iDLD (NCT05552365)
- Testing
- Adapted Cognitive Behavioural, Treatment as Usual
- Where
- Singapore
- Volunteers
- 9 people
- Sponsor
- Nanyang Technological University
ADHD, Dyslexia
Dual Executive Function Training Package
Executive function (EF) refers to the cognitive processes that enable goal-directed regulation of thoughts, emotions, and behaviours.
- Conditions
- ADHD, Dyslexia, Autism
- Trial name
- NCT07262853
- Testing
- Executive Function Training
- Where
- Hong Kong
- Volunteers
- 288 people
- Sponsor
- Education University of Hong Kong
Autism, Mental Retardation
MR Scanning of Very Young Children With Severe Developmental Disorders
The specific is to study the MR morphologic and spectroscopic brain correlates and predictors of development in children with severe developmental disorders (autistic spectrum disorders and/or mental retardation and/or language…
- Conditions
- Autism, Mental Retardation, Language Disorder
- Trial name
- NCT00156221
- Where
- Netherlands
- Sponsor
- UMC Utrecht
Autism Spectrum Disorder (ASD)
Navigating the Transition to Adulthood: A Dual Language Mobile App for Latino Youth With ASD and Their Families
The purpose of this study is to determine useability and satisfaction characteristics,product usage data,methodological feasibility parameters and feasibility metrics of the mHealth app adapted intervention on the mental health…
- Trial name
- NCT07170163
- Testing
- ¡Iniciando! mHealth App
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston