Clinical trials: Lactic Acid
Lactic Acidosis
Remote Ischemic Preconditioning During Cardiopulmonary Bypass
The objective of study is to detect effect of remote ischemic preconditioning on serum lactate levels during and after cardiac surgery with cardiopulmonary bypass in addition to its effect on cardiac and renal clinical outcomes.
- Trial name
- RIPC (NCT03723993)
- Testing
- Inflated cuff, Non inflated cuff
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fayoum University
Hip Replacement Arthroplasty
Comparison Between Two Techniques of Volemic Expansion in Hip Replacement Arthroplasty
Currently the most use solution to volemic reposition in hip replacement arthroplasty is the crystalloid solution. This trial intends to compare two different volemic replacements: HES and Ringer's lactate.
- Trial name
- NCT00542516
- Testing
- Hydroxyethyl Starch, Ringer's lactate
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Wrinkles in Decolletage
An Open-label Study of Poly-l-lactic Acid for Correction of Wrinkles in the décolletage Area
This is a prospective open-label study to evaluate safety and effectiveness of two different reconstitution volumes of poly-l-lactic acid (PLLA) for correction of wrinkles in the décolletage area.
- Trial name
- NCT05538728
- Testing
- poly-l-lactic acid (Sculptra)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Trauma
Surgical Stress Measured by Microdialysis
Paraspinal muscle damage is inevitable during conventional posterior lumbar fusion surgery. Minimal invasive surgery is postulated to result in less muscle damage and better outcome.
- Trial name
- NCT01495143
- Testing
- Posterolateral lumbar fusion surgery
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark
Post-exercise Sport Students
THE EFFECT OF ACUPUNCTURE ON THE BLOOD LACTIC ACID LEVELS
Background: In sports, recovery after exercise is a very important process for athletes. Several studies have shown that the rate of disease associated with athlete's recovery can be increased by several modalities, one of which…
- Trial name
- NCT04892784
- Testing
- Press tack needle acupuncture
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Hygiene
Dermacyd PH_DETINLYN Tangerine Mix (Lactic Acid) - Photo Evaluation
The purpose of this study is to demonstrate the absence of photoirritation and photosensitization potential of the product Dermacyd PHDETINLYN Tangerine Mix (Lactic Acid).
- Trial name
- NCT00784056
- Testing
- Lactic Acid (Dermacyd PH_DETINLYN Tangerine Mix)
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Sanofi
Hyponatremia
Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children
In children fluids are supplemented during surgery to provide volume, to maintain blood glucose levels, electrolyte balance and to meet the ongoing fluid losses during surgery.
- Trial name
- NCT02936167
- Testing
- Ringer Lactate, Plasmalyte
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Type 2 Diabetes, Obesity
Lactate and Glycerol Contribution to Gluconeogenesis
A major cause of increased blood glucose levels in type 2 diabetes (T2D) is increased hepatic gluconeogenesis (GNG), as the liver converts various substrates into glucose.
- Conditions
- Type 2 Diabetes, Obesity, Healthy
- Trial name
- NCT06955130
- Testing
- Glycerol, Lactate, Glucose
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Episiotomy, Wound Healing
Use of Lactic Acid Gel for Intravaginal Use, 7 Applicators x 5ml, Bayer to Reduce Post-episiotomy Discomfort
This prospective controlled study evaluates the efficacy of topical lactic acid gel in enhancing episiotomy wound healing and improving postpartum sexual quality of life.
- Conditions
- Episiotomy, Wound Healing, Postpartum Period
- Trial name
- LA30051990 (NCT06978049)
- Testing
- Topical Lactic Acid Gel (BAYER)
- Where
- Romania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta
Exercise Physiology, Nutritional Supplementation
Effects of Pre-Run Nutritional Supplements During a Fixed-Pace 5 km Treadmill Run
This study will examine how three commonly used pre-run nutritional supplements-caffeine, L-citrulline, and an exogenous ketone supplement-affect physiological and perceptual responses during a fixed-pace 5 km treadmill run in…
- Trial name
- NCT07854223
- Testing
- Caffeine, L-Citrulline, Exogenous Ketone (Beta-Hydroxybutyrate)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Circadian Rhythm
Effect of Circadian Rhythm on Brain NAD Measured by Phosphorus Magnetic Resonance Spectroscopy at 7 Tesla
The Discovery of the circadian clock first established a genetic basis for behavior, and our understanding of circadian rhythm (CIR) has since expanded to provide molecular insights into physiology and disease.
- Trial name
- ChronoBrain (NCT05093088)
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Cellulite
Safety and Effectiveness of Poly-l-lactic Acid (PLLA) for the Improvement in Appearance of Cellulite
This pilot study has been designed to evaluate the safety and effectiveness of PLLA as a single regimen for the improvement in appearance of cellulite after changes in reconstitution procedure.
- Trial name
- NCT05064761
- Testing
- Sculptra new dilution
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Energy Expenditure, Body Composition
The Energy Cost of 1-Hour Football Training
This study aims at investigating the energy expenditure following a single Football trainning session in middle aged males. The participants will perform a soccer training session [A single training session including 60 minutes…
- Conditions
- Energy Expenditure, Body Composition, Resting Metabolic Rate, Overweight and Obesity
- Trial name
- FAM (NCT06477705)
- Testing
- FAM
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Metabolic Disturbance
Isothiocyanates and Metabolic Health
Many sprouts, for example broccoli sprouts, contain substances that have shown to have protective effects, both against oxidative stress and against carcinogenic substances.
- Trial name
- IMH (NCT05070585)
- Testing
- Isothiocyanate rich sprouts
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The Swedish School of Sport and Health Sciences
Atrophic Acne Scarring
Poly-L-Lactic Acid in Atrophic Acne Scars
Background: Management of atrophic acne scars remains challenging due to their heterogeneous morphology and suboptimal response to conventional therapies.
- Trial name
- NCT07523217
- Testing
- injectable PLLA, PLLA threads
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
HIIT
Effect of Different Work-to-rest Ratios During Simulated Taekwondo Combat on Blood Lactate, Heart Rate and Perceptual Responses in Elite Taekwondo Athletes
This randomized cross-over study measured physiological and perceptual responses of taekwondo athletes following a free combat and combats with different W:R ratios. This study was carried out with 4 visits.
- Trial name
- NCT07395414
- Testing
- Free combat, 1:2 work to rest ratio, 2:1 work to rest ratio
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Critical Illness, D-Lactate
Diagnostic And Prognostic Value Of D-Lactate And Scube-1 Levels In Critically Ill Patients
The investigators aimed to investigate the diagnostic and prognostic levels of D-Lactate and SCUBE-1 in critically ill patients being admitted to the emergency department.
- Conditions
- Critical Illness, D-Lactate, SCUBE-1
- Trial name
- NCT06704438
- Testing
- D-Lactate
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Central Venous Oxygen Saturation, Anaemia
Transfusion Practices in Intensive Care Units: a Hungarian Nationwide Survey
The aim of our data analysis-based questionnaire study is to assess the daily transfusion practices used in the care of critically ill patients in intensive care units in Hungary.
- Conditions
- Central Venous Oxygen Saturation, Anaemia, Lactate, Transfusion
- Trial name
- NCT07532772
- Testing
- Survey using a questionnaire.
- Where
- Hungary
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Pest County Flór Ferenc Hospital
Irisin, Lactate
Temporal Dynamics of Irisin
Purpose The purpose of this study was to determine the peak point of irisin following exercises of different intensities. Method This randomized crossover controlled trial aimed to examine the acute effects of three experimental…
- Conditions
- Irisin, Lactate, Exercise Intensity
- Trial name
- TIDIER (NCT07191015)
- Testing
- Low-Intensity Continuous Exercise, Moderate Intensity Interval Exercise, High-Intensity Interval Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aksaray University Training and Research Hospital
Hygiene
Dermacyd Silver Frutal (Lactic Acid) - Acceptability.
Primary Objective: To prove the safety of the gynecological formulation in normal conditions of use.
- Trial name
- NCT00933413
- Testing
- LACTIC ACID(ND)
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sanofi