Clinical trials: Lactate
Vaginal Candidiasis, Vulvovaginal Candidiasis
Evaluation of VagiVitalAC for Treatment of Candida Vulvovaginitis
Candidiasis is an infection caused by a yeast (a type of fungus) called Candida. Candidiasis in the vagina is commonly called a "vaginal yeast infection." Another names for this infection is "vaginal candidiasis".
- Conditions
- Vaginal Candidiasis, Vulvovaginal Candidiasis, Candidal Vulvovaginitis
- Trial name
- NCT05012852
- Testing
- VagiVitalAC
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- PepTonic Medical AB
MELAS Syndrome
Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome
The purpose of this study is to assesses the efficacy of oral supplementation with glutamine over three months on several amino acids and lactate concentration measured in cerebrospinal fluid and cerebral lactate measured by…
- Trial name
- NCT04948138
- Testing
- Glutamine oral supplementation
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- Jesús González de la Aleja Tejera
Mitochondria, Metformin
Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. Metformin Monotherapy
he goal of this clinical trial is to compare the mitochondrial redox effects of imeglimin versus metformin monotherapy in adults with newly diagnosed Type 2 diabetes mellitus who are treatment-naive.
- Trial name
- MIRROR-DM (NCT07436182)
- Testing
- Imeglimin, Metformin 1000 mg Oral Tablet
- Where
- Egypt
- Volunteers
- 176 people
- Sponsor
- Mansoura University
Severe Chronic Obstructive Pulmonary Disease, Dyspnea
The Effectiveness Pulmonary Telerehabilitation and Cognitive Telerehabilitation in COPD Patients
The aim of our study is to compare the effectiveness of the supervized pulmonary telerehabilitation program and the cognitive telerehabilitation method, which includes pulmonary telerehabilitation methods, in patients with severe…
- Conditions
- Severe Chronic Obstructive Pulmonary Disease, Dyspnea, Muscle Weakness, Fatigue
- Trial name
- NCT05222295
- Testing
- Supervised Pulmonary Telerehabilitation, Cognitive Telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Saglik Bilimleri Universitesi
Septic Shock, Sepsis
Discordance Between Capillary Refill Time and Oxygen Extraction Ratio in Septic Shock
In septic shock, restoring large-vessel (macrocirculatory) perfusion-reflected by a normal capillary refill time (CRT)-does not always mean that oxygen use at the tissue level has recovered.
- Trial name
- DISCO-SHOCK (NCT07774962)
- Testing
- Capillary refill time (CRT), Oxygen extraction ratio (O₂ER) assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Hygiene
Lactacyd Radiance (Lactic Acid) Prophetic Patch Test
Primay objective: To evaluate the potential of the products in eliciting adverse skin reaction.
- Trial name
- NCT00679562
- Testing
- Lactic Acid, Distilled water
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sanofi
Heart Arrest
Oxidative Stress and Cardiac Arrest
Cardiac arrest is a major health problem reaching 375000 cases in Europe each year. Only 5 to 31 % survive after an out of hospital cardiac arrest (OHCA). The main complication after OHCA is the anoxic encephalopathy.
- Trial name
- NCT00888966
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Institut d'Anesthesiologie des Alpes Maritimes
Severe Sepsis, Septic Shock
Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation
The purpose of this study is to determine if there is equivalence between two different methods of treating patients with severe bloodstream infection called sepsis.
- Trial name
- LactATES (NCT00372502)
- Testing
- Modified EGDT, Standard EGDT
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Fluid and Electrolyte Imbalance
Volume Kinetics of Fluid Resuscitation in Early Sepsis
The recommended volume resuscitation for patients with early sepsis-induced hypoperfusion is at least 30 ml/kg of crystalloid administered within the first three hours.
- Trial name
- NCT06499701
- Testing
- Ringer's Lactate
- Where
- 2 sites in Romania
- Volunteers
- 13 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
Athletic Performance, Physical Endurance
Event-Specific Adaptations to CrossFit and Running-Based HIIT in Elite Distance Runners at Moderate Altitude
The goal of this clinical trial is to compare the effects of two high-intensity training programs on physical performance and physiological adaptations in elite male middle- and long-distance runners aged 25 to 35 years who live…
- Conditions
- Athletic Performance, Physical Endurance, Altitude Training Adaptation, Aerobic Capacity
- Trial name
- NCT07675577
- Testing
- Running-Based High-Intensity Interval Training (HIIT), CrossFit-Based High-Intensity Training (CF)
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Septic Shock, Hyperlactatemia
Early Goal Directed Therapy Using a Physiological Holistic View. The ANDROMEDA-SHOCK Study
Septic shock is a highly lethal condition associated with a mortality risk of 30 to 60%. Optimizing tissue perfusion and oxygenation is the aim to decrease mortality and morbidity in septic shock patients.
- Conditions
- Septic Shock, Hyperlactatemia, Peripheral Perfusion
- Trial name
- ANDROMEDA (NCT03078712)
- Testing
- Peripheral Perfusion guided resuscitation, Lactate guided resuscitation
- Where
- Chile
- Volunteers
- 424 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Hygiene
Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower - Compatibility
The purpose of this study is to demonstrate the absence of irritation potential (primary dermical irritability and cumulated dermical irritability) and allergy (sensibilization) of the product Dermacyd PHDETINBACK Sweet Flower.
- Trial name
- NCT00785681
- Testing
- Dermacyd PH_DETINBACK (Lactic Acid)
- Where
- Brazil
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Sanofi
Skin Laxity, Facial Aging
RESTRUCTURING THE MANDIBULAR ANGLE IN FACIAL AGING: A NOVEL TECNIQUE USING POLY-L-LACTIC ACID
Skin laxity is a common complaint among patients seeking aesthetic dermatological interventions, affecting the facial contour, especially in the mandibular angle, due to bone aging and the loss of tissue support in the lower…
- Trial name
- NCT06948045
- Testing
- PLLA application to the mandibular angle
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Doris Hexsel
Coronary Artery Disease
Association Between Intraoperative Pulse Pressure Variation and Postoperative Lactate Clearance in Cardiac Surgery
This study aims to evaluate the relationship between intraoperative pulse pressure variation (PPV) and postoperative lactate clearance in adult patients undergoing elective cardiac surgery.
- Trial name
- NCT07871188
- Testing
- No Study-Specific Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Elzem SEN
Hygiene
Dermacyd PH_DETINLYN (Lactic Acid) Sweet Flower - Photo Evaluation.
To demonstrate the absence of photoirritation and photosensitization potential of the product Dermacyd PHDETINLYN Sweet Flower.
- Trial name
- NCT00785590
- Testing
- Dermacyd PH_DETINLYN (Lactic Acid)
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Sanofi
Dietary Supplements, Heart Rate/Drug Effects
Caffeine and Sodium Citrate Ingestion
A positive ergogenic effect of sodium citrate and caffeine ingestion in a short-term, high-intensity exercise task was shown by several studies. These studies were conducted with healthy, able-bodied subjects.
- Conditions
- Dietary Supplements, Heart Rate/Drug Effects, Lactic Acid/Metabolism, Physical Education and Training/Methods
- Trial name
- NCT01591226
- Testing
- Caffeine, Sodium Citrate, Mannitol
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Sepsis, Sepsis Bacterial
A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor
The overall purpose of this study is to demonstrate the usability of a clinical-grade device in the form of a finger clasp similar to a pulse oximeter for monitoring lactate values, by comparing its performance in reading…
- Conditions
- Sepsis, Sepsis Bacterial, Lactate Blood Increase, Infectious Disease
- Trial name
- NCT04796285
- Testing
- Lab Clasp
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Surgery Stress
The Effects of Erector Spinae Plane (ESP) Block on Surgery-related Stress Response in Cardiac Surgery With ERAS
Surgery-induced pain reveals its own metabolic and inflammatory responses, resulting in a further increase in noxious pathways that are already occurring.
- Trial name
- NCT04924335
- Testing
- Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara City Hospital Bilkent
Lactate Values During Labour in Women Receiving Neuraxial Anaesthesia
Lactate Values During Labour and Their Correlation With Maternal and Foetal Outcome
Postpartum haemorrhage (PPH) represents a significant cause of morbidity in the obstetric population, with a mortality rate of 140,000 women per year, and the predominant cause of PPH (70%) is uterine atony.
- Trial name
- NCT06807255
- Testing
- Lactate levels were assessed via a venous blood gas test utilising an IV cannula already placed in the woman's limb upon admission
- Where
- Italy
- Volunteers
- 303 people
- Sponsor
- Papa Giovanni XXIII Hospital
Hygiene
Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid) - Safety.
The purpose of this study is to prove the safety in normal conditions of useof the product Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid).
- Trial name
- NCT00783939
- Testing
- Lactic Acid
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sanofi