Clinical trials: Labor Onset and Length Abnormalities
Labor Onset and Length Abnormalities, 37 or More Completed Weeks of Gestation
Comparative Study Between Using WHO Labour Care Guide & Modified WHO Partograph
This randomized clinical trial is based on comparing the efficiency of modified WHO partographs vs. the new WHO labour care guide in monitoring and assessing the outcome of labour.
- Conditions
- Labor Onset and Length Abnormalities, 37 or More Completed Weeks of Gestation, First Birth
- Trial name
- NCT06537089
- Testing
- Supportive care measures, LCG guided labour interference
- Where
- Egypt
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hend Mahmoud Abdelghany
Labor Onset and Length Abnormalities, First Birth
Use of Cinnamomum Verum for Induction of Labor. Double Blind Randomized Clinical Trial
The purpose of the research protocol is to evaluate the effectiveness of Cinnamomum verum extract for the initiation of labor. Cinnamaldehyde ((E)-3-Phenylprop-2-enal) is an α, β unsaturated aromatic aldehyde, derived from…
- Trial name
- CINNALAB (NCT06164613)
- Testing
- Cinnamomum Verum oil extract
- Where
- Honduras
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Labor Onset and Length Abnormalities
Effect of Tafoxiparin on Cervical Ripening and Induction of Labor in Term Pregnant Women With an Unripe Cervix
The study is designed as a randomized, Double-Blind, Placebo-Controlled, Parallel-Group Proof of Concept Study (section A) with a conditional dose finding follow up (Section B) to Evaluate the Efficacy on Cervical ripening…
- Trial name
- NCT04000438
- Testing
- DF01, PL1
- Where
- 7 sites in Finland, Sweden
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Dilafor AB
Labor Onset and Length Abnormalities, Pregnancy Related
LaPPS: Labor Podcast for Patient Satisfaction
Patients will be enrolled at 28w0d-36w0d. Randomized to one of two arms: 1. Labor podcasts - Seven labor podcasts that can be downloaded for any podcast app 2. Usual care
- Trial name
- LaPPS (NCT04933708)
- Testing
- Labor Podcast
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Labor Dystocia, Labor Complication
The Norwegian World Health Organisation Labour Care Guide Trial (NORWEL)
Appropriate and timely care during birth is critical to the survival and health of women and their babies. In 2020, the World Health Organization (WHO) presented the Labour Care Guide (LCG) as the new recommended tool for…
- Conditions
- Labor Dystocia, Labor Complication, Labor Onset and Length Abnormalities, Labor (Obstetrics)--Complications
- Trial name
- NORWEL (NCT05791630)
- Testing
- the labour care guide (LCG)
- Where
- 10 sites in Norway
- Volunteers
- 23,650 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Induced; Birth, Labor Onset and Length Abnormalities
Papaverine and Oxytocin vs Oxytocin Alone in Labor Induction
This study aims to evaluate the efficacy and safety of combining papaverine with oxytocin for labor induction compared to oxytocin alone
- Trial name
- NCT06547437
- Testing
- Papaverine, normal saline
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Labor Onset and Length Abnormalities, Induced; Birth
Comparison of Misoprostol Ripening Efficacy With Dilapan
The purpose of this study is to find out if Dilapan works as well as Misoprostol for preparing the mouth of the uterus (cervix) for inducing labor in women who need to undergo this procedure.
- Trial name
- COMRED (NCT03670836)
- Testing
- Dilapan, Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Columbia University
Pregnancy Related, Obesity
Misoprostol Dosing in BMI Greater Than 30
The investigators are performing a randomized controlled-trial investigating if 50mcg (compared to 25 mcg) of vaginal misoprostol reduces the time from induction start to delivery in obese women.
- Conditions
- Pregnancy Related, Obesity, Labor Onset and Length Abnormalities
- Trial name
- MD30 RCT (NCT05262738)
- Testing
- 50 Micrograms Vaginal Misoprostol (Intervention), 25 Micrograms Vaginal Misoprostol (Control)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Texas at Austin
Labor; Forced or Induced, Affecting Fetus or Newborn, Labor Onset and Length Abnormalities
Clinical Evaluation of Cervical Ripening in the Outpatient Setting
A randomized controlled trial of mifepristone 200mg vs balloon catheter for cervical ripening.
- Trial name
- NCT04271722
- Testing
- Cervical ripening
- Where
- Portugal
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar Lisboa Norte
Labor Onset and Length Abnormalities
Misoprostol Versus Oxytocin for Induction of Labour in Parturients With Spontaneous Rupture of Fetal Membranes at Term
Intravenous oxytocin titration has a prime position as a choice agent for induction of labour following term PROM as it has been shown to be efficacious for such purpose.
- Trial name
- NCT06343480
- Testing
- Labour Induction
- Where
- 2 sites in Nigeria
- Volunteers
- 120 people
- Sponsor
- Federal Teaching Hospital Abakaliki
Labor Onset and Length Abnormalities
Laminaria Tents Versus Vaginal Prostaglandin in Cervical Ripening
Mechanical methods used for induction of labor received a great attention nowadays due to the serious side effects of the pharmacological methods. Hygroscopic dilators are considered important subtype of these mechanical methods.
- Trial name
- NCT06151925
- Testing
- Laminaria, Vaginal prostaglandin
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Labor Onset and Length Abnormalities
Breath Metabolomics in the Laboring Parturient
This is primarily a feasibility study to determine whether quantitative measurement of volatile organic compounds (VOCs) in the breath of parturients undergoing labor is possible.
- Trial name
- NCT04564196
- Testing
- Breath Sample
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Stanford University
Obesity, Labor Onset and Length Abnormalities
Ambulation With Labor Epidural in Obese Women
The purpose of this study is to determine if ambulation with a labor epidural in place is associated with decreased rate of cesarean delivery in obese patients.
- Trial name
- NCT04504682
- Testing
- Ambulation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Labor Onset and Length Abnormalities
Goal-directed Labor Epidural Analgesia Maintenance
The GLEAM trial is a multicenter, pragmatic, cluster-randomized trial to assess the effects of programmed intermittent epidural bolus versus continuous epidural infusion on the rate of spontaneous vaginal delivery and several…
- Trial name
- GLEAM (NCT05255263)
- Testing
- PIEB, CEI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Labor Onset and Length Abnormalities, Prolonged Labor
Quantifying the Impact of the Peanut Ball on the Duration of the Active Stage of Labor
Prolonged labor is associated with adverse maternal and fetal outcomes including infection, postpartum hemorrhage and increased NICU admission. One of the most common indications for cesarean section in the US is prolonged labor.
- Conditions
- Labor Onset and Length Abnormalities, Prolonged Labor, Labor Long, Labor; Poor
- Trial name
- NCT05489315
- Testing
- Positioning with peanut ball, Traditional positioning
- Where
- 4 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Labor Onset and Length Abnormalities, Uterine Rupture
Breast Stimulation vs. Low Dose Oxytocin Augmentation for Labor Induction
To find the preferred method of labor induction (birth augmentation) for women with a history of one prior cesarean section scar and in grandmultiparas, the difference in time interval from augmentation to delivery will be…
- Conditions
- Labor Onset and Length Abnormalities, Uterine Rupture, Birth; Induced
- Trial name
- NCT05510310
- Testing
- Breast stimulation, Oxytocin
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Western Galilee Hospital-Nahariya
Labor Onset and Length Abnormalities
Engagement of Fetal Head as a Predictor of a Successful Vaginal Delivery in Primigravidas Presented in Early Labor.
In primigravida, Delayed engagement of fetal head has been theorized that it is more likely in women with a possible cephalo-pelvic disproportion, so far they are associated with higher risk of cervical dystocia, which led to…
- Trial name
- NCT05084326
- Testing
- Engagement of fetal head as a predictor of a successful vaginal delivery
- Where
- Egypt
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- mohamed abosena
Obesity Complicating Childbirth, Obesity
The MODE Trial: Planned Caesarean Section Versus Induction of Labour for Women With Class III Obesity
Canadian guidelines recommend that women with a pre-pregnancy body mass index (BMI) at or above 40 kg/m2 deliver by their due date.
- Conditions
- Obesity Complicating Childbirth, Obesity, Labor Onset and Length Abnormalities, Pregnancy, High Risk
- Trial name
- MODE (NCT03985618)
- Testing
- Caesarean section, Induction of Labour
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ottawa Hospital Research Institute
Labor Onset and Length Abnormalities
Effect Mobility During Induction of Labor on Time to Delivery. A Randomized Controlled Trial
this is a andomized controlled trial the evaluates the effect of enhanced mobility, controlled via electronic pedometers, during induction of labor by extra amniotic balloon on time to delivery.
- Trial name
- NCT03784092
- Testing
- feedback
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Labour Onset and Length Abnormalities, Labor; Forced or Induced, Affecting Fetus or Newborn
Dilapan-S/Dilasoft E-Registry in Induction of Labor
International Observational E-Registry on the use of DILAPAN-S® osmotic dilator / DILASOFT® osmotic dilator for cervical ripening prior to labour induction.
- Trial name
- DSREGISTRYIL (NCT02318173)
- Testing
- Dilapan-S
- Where
- 11 sites in United States, Czechia and 5 more
- Volunteers
- 444 people
- Sponsor
- Medicem International CR s.r.o.