Clinical trials: Labor (Obstetrics)--Complications
Labor (Obstetrics)--Complications
Uterocervical Angle Versus Cervical Length as a Predictor of Labor Induction in Term Singleton Pregnancy
Induction of labor is frequently performed in all obstetric clinics. Failed IOL has been defined in many different ways.Bishop scoring, which is a traditional and subjective method, is more frequently evaluated with cervical…
- Trial name
- NCT06558500
- Testing
- Uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Pregnancy Complications
Impact of Age at Conization on Obstetrical Outcome: A Case-Control Study
The maternity ward attached to the colposcopy clinic was also the obstetrical referral center for the region and carried out approximately 2500 deliveries per year.
- Trial name
- OBSTETRICON (NCT05765188)
- Testing
- loop electrosurgical excision procedure
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Obstetric Labor Complications
MRI Pseudo-CT Sequences for Obstetrical Pelvimetry.
It is possible to perform a pelvimetry by MRI as a substitute to pelvimetry by CT, hence sparing the patient from a dose of irradiation.
- Trial name
- Pelvi-MRI (NCT06485323)
- Testing
- MRI pelvimetry
- Where
- Belgium
- Volunteers
- 95 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Other Specified Complications of Labor and Delivery
Vaginal Delivery Debrief Checklist to Improve Team Communication
This study is to determine if using a standardized debrief checklist after vaginal delivery improves communication between the vaginal delivery health care team members and if using the checklist increases a sense of enhanced…
- Trial name
- VDD (NCT01822158)
- Testing
- Vaginal Delivery Debrief Checklist
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Providence Health & Services
Periodontitis, Infant, Premature
Obstetrics and Periodontal Therapy (OPT) Study
The purpose of this study is to determine if non-surgical periodontal (gum) treatment can reduce the incidence of preterm birth and low birth weight babies in mothers with periodontitis (gum disease).
- Trial name
- OPT (NCT00066131)
- Testing
- Periodontal scaling and root planing, Scaling and root planing
- Where
- United States
- Volunteers
- 823 people
- Sponsor
- University of Minnesota
Pregnant With Complication, Preeclampsia
Developing & Evaluating Models for Early Predicting Obstetrical Diseases in Pregnant Women by Non-invasive Prenatal Test
This is Observational study, aiming to investigate the potentiality of cffDNA and cfRNA by a non-invasive test, in combination with clinical characteristics, to establish models for early screening and predicting high-risk…
- Conditions
- Pregnant With Complication, Preeclampsia, Preterm Birth, Gestational Diabetes
- Trial name
- NCT06385366
- Where
- Vietnam
- Volunteers
- 1,105 people
- Sponsor
- Gene Solutions
Labor (Obstetrics)--Complications, Labor; Dyscoordinate
Biomarkers of Uterine Muscle Physiology
This observational study characterizes the relationship between amniotic fluid lactate and uterine electromyography during labor in healthy individuals at term planning a vaginal birth.
- Trial name
- BUMP (NCT04251702)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pregnancy Related, Epidural; Anesthesia, Headache
Inertial Sensors for Obstetrical Walking Epidural Tracking
Freedom of movement and the ability to walk are crucial during the first stage of labor, potentially reducing labor duration, cesarean section risk, epidural analgesia use, and bladder catheterization.
- Conditions
- Pregnancy Related, Epidural; Anesthesia, Headache, Labor Complication
- Trial name
- MOTION-EASE (NCT06471790)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Prelabor Rupture of Membranes, Labor (Obstetrics)--Complications
Early V/S Delayed Induction of Labour in Patients With Prelabour Rupture of Membranes
To compare the effects of early V/s delayed induction of labour and its outcomes in patients presenting with PROM without labour.
- Conditions
- Prelabor Rupture of Membranes, Labor (Obstetrics)--Complications, Induction of Labor
- Trial name
- PROM (NCT07261332)
- Testing
- 0.5mg PGE2 gel
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Laiba Qamar
Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary
Magnesium for Neonatal Neuroprotection and Mothers
Magnesium is a treatment for mothers to protect brains of babies born early. This study investigates combined effects of magnesium and spinal or epidural anesthesia on mothers having cesareans.
- Conditions
- Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary, Respiratory Depression
- Trial name
- MnMs (NCT01482078)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Analgesia, Obstetrical, Post-Dural Puncture Headache
Intrathecal Catheter Placement Versus Resiting Epidural Catheter After Dural Puncture in Obstetric Patients
Epidural anesthesia represents the most popular method for pain relief during labour. Unintentional dural puncture (UDP) occurs in 0.4-1.5% of labour epidural analgesia, representing therefore the most common complication.
- Trial name
- ItaREVI (NCT05977361)
- Testing
- Resiting Epidural Catheter, Intrathecal Catheter Placement
- Volunteers
- 181 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
PPH - Postpartum Hemorrhage, Eclampsia
Comparing Simulated Patients and Manikin Based Simulation in Obstetrics
The aim of this randomized study is to compare a live, trained simulated patient with a high-fidelity manikin in obstetric emergency team training using two standardized scenarios.
- Trial name
- NCT07857551
- Testing
- Trained, standardized patient, MamaAnne Patient Simulator
- Where
- Austria
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Parturition, Analgesia, Obstetrical
Neuraxial Labor Analgesia and the Incidence of Postpartum Depression
Postpartum depression (PPD) affects approximately 15% of women during the first year after giving birth, and is common across cultures. The etiology of postpartum depression is not totally clear.
- Conditions
- Parturition, Analgesia, Obstetrical, Depression, Postpartum
- Trial name
- NCT02823418
- Testing
- No neuraxial labor analgesia, Neuraxial labor analgesia
- Volunteers
- 599 people
- Sponsor
- Peking University First Hospital
Labor Dystocia, Labor Complication
The Norwegian World Health Organisation Labour Care Guide Trial (NORWEL)
Appropriate and timely care during birth is critical to the survival and health of women and their babies. In 2020, the World Health Organization (WHO) presented the Labour Care Guide (LCG) as the new recommended tool for…
- Conditions
- Labor Dystocia, Labor Complication, Labor Onset and Length Abnormalities, Labor (Obstetrics)--Complications
- Trial name
- NORWEL (NCT05791630)
- Testing
- the labour care guide (LCG)
- Where
- 10 sites in Norway
- Volunteers
- 23,650 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Pregnancy, Preterm Labor
Biomarkers in Obstetrical Complications
Objective: To study the natural history of normal pregnancy and the most frequent pregnancy complications responsible for the excessive rate of perinatal morbidity and mortality, in order to develop models to predict the…
- Conditions
- Pregnancy, Preterm Labor, Maternal Fetal Factors, Preterm Birth
- Trial name
- NCT03480139
- Where
- United States
- Volunteers
- 746 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hemorrhage, Postpartum
Haemorrhagia Postpartum: an Implementation Study on the NVOG Guidelines and MOET Instructions
The objectives of this study is first to asses to what extent the guidelines of the Dutch Society of Obstetrics and Gynaecology (NVOG) and the MOET (Management of Obstetric and Emergencies and Trauma) instructions for…
- Trial name
- Fluxim (NCT00928863)
- Testing
- implementation aids
- Where
- Netherlands
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- ZonMw: The Netherlands Organisation for Health Research and Development
Obstetric Labor Complications, Prolonged Pregnancy
Study of the Effect of Eicosanoids on Contractile Activity of Pregnant Human Myometrium in Pathological Situation
Recent studies show that EET and 20-HETE have important biological effects, particularly in the vascular system. The investigators studied the effect of eicosanoids on the gravid rat uterus.
- Trial name
- EAU2 (NCT00939744)
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- Université de Sherbrooke
Postpartum Hemorrhage, Cesarean Section Complications
Tranexamic Acid in Patients for Caesarian Delivery.
This is a prospective, double-blinded, randomized placebo-controlled trial. The study will be approved by the DUHS institutional review board (IRB) and the trial will be registered at clinical trial registry.
- Conditions
- Postpartum Hemorrhage, Cesarean Section Complications, Obstetric Anesthesia Problems
- Trial name
- TXA; CD (NCT05759156)
- Testing
- Tranexamic acid injection
- Where
- Pakistan
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Postpartum Hemorrhage, Uterine Atony
Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage
The objective of the study is to demonstrate whether cooling the uterine smooth muscle during cesarean section (following delivery of the fetus) will promote better uterine contraction and involution resulting in lower blood…
- Trial name
- NCT02229513
- Testing
- Uterine Cooling
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Obstetrical Complications, Hemorrhage
Tranexamic Acid for the Prevention of Obstetrical Hemorrhage After Cesarean
A randomized placebo-controlled trial of 11,000 women to assess whether tranexamic acid as prophylaxis lowers the risk of postpartum hemorrhage in women undergoing a cesarean delivery.
- Conditions
- Obstetrical Complications, Hemorrhage, Labor and Delivery
- Trial name
- TXA (NCT03364491)
- Testing
- Tranexamic Acid
- Where
- 12 sites in United States
- Volunteers
- 11,000 people
- Sponsor
- The George Washington University Biostatistics Center