Clinical trials: Labor, Induced
Preeclampsia, Obstetric Labor Complications
Pravastatin to Prevent Preeclampsia
This study is a double-blind randomized placebo-controlled trial of 1,550 high-risk women to assess whether daily treatment with pravastatin administered early in pregnancy reduces the rate of a composite outcome of preeclampsia…
- Conditions
- Preeclampsia, Obstetric Labor Complications, Hypertension in Pregnancy
- Trial name
- Pravastatin (NCT03944512)
- Testing
- Pravastatin
- Where
- 12 sites in United States
- Volunteers
- 102 people
- Sponsor
- The George Washington University Biostatistics Center
Labor, Induced, Patient Preference
Should I Have an Elective Induction?
The goal of the proposed study is to perform a pilot test of a patient-centered decision support tool to help pregnant people and providers work together in making informed, shared decisions regarding whether or not to opt for…
- Trial name
- SELECTION (NCT05838313)
- Testing
- Elective Induction of Labor Decision Support Tool
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Labor Onset and Length Abnormalities, Induced; Birth
Comparison of Misoprostol Ripening Efficacy With Dilapan
The purpose of this study is to find out if Dilapan works as well as Misoprostol for preparing the mouth of the uterus (cervix) for inducing labor in women who need to undergo this procedure.
- Trial name
- COMRED (NCT03670836)
- Testing
- Dilapan, Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Columbia University
Labor, Induced, Cervix Uteri-Diseases
Comparing Outpatient to Inpatient Cervical Ripening Using Dilapan-S®
The target population for our study is women who present for induction of labor. If there is a decision by the obstetrical team to place a mechanical dilator for cervical ripening, the obstetrical team will notify the research…
- Trial name
- HOMECARE (NCT03665688)
- Testing
- Outpatient Dilapan-S, Inpatient Dilapan-S
- Where
- 2 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Obesity, Labor, Induced
Oxytocin Dosage to Decrease Induction Duration
This is a randomized controlled trial in which women are allocated either 'high dose' or 'low dose' oxytocin infusions for induction of labour. The randomization is stratified by maternal body mass index.
- Conditions
- Obesity, Labor, Induced, Oxytocin
- Trial name
- OPS (NCT03140488)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Arizona
Labor; Forced or Induced, Affecting Fetus or Newborn, Pregnancy
A Comparison of Oral Misoprostol and Vaginal Misoprostol for Cervical Ripening and Induction of Labor
The purpose of this study is to study if misoprostol administered orally is at least as effective as misoprostol administered vaginally for cervical ripening and the induction of labor.
- Trial name
- NCT02777190
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Labor; Forced or Induced, Affecting Fetus or Newborn
Is More Than One Dose of Misoprostol Needed to Expedite Vaginal Delivery in a Patient With an Unripe Cervix?
The goal of this study is to determine whether inducing labor with just one dose of misoprostol, followed by treatment with oxytocin, will still be effective enough to increase the chances of having a successful vaginal delivery…
- Trial name
- NCT02680314
- Testing
- Misoprostol
- Volunteers
- 243 people
- Sponsor
- Montefiore Medical Center
Pregnancy, Labor, Induced
Foley Bulb With Oral Misoprostol for Induction of Labor
Induction of labor is associated with increased cesarean delivery rates, particularly in women with an unfavorable cervix. Both pharmacologic and mechanical methods are utilized for cervical ripening and labor induction.
- Trial name
- NCT03407625
- Testing
- Foley bulb plus Oral Misoprostol, Oral Misoprostol
- Where
- United States
- Volunteers
- 2,227 people
- Sponsor
- University of Texas Southwestern Medical Center
Labor, Induced, Cervical Ripening
Prehospital Cervical Ripening Before Induction and the Maternal Experience
This is a randomized study evaluating the impact of pre-hospital cervical ripening with a transcervical Foley balloon before labor induction in full-term pregnancies on the length of inpatient labor induction and maternal…
- Trial name
- "PRIME" (NCT01641601)
- Testing
- Outpatient transcervical Foley balloon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
Labor; Forced or Induced, Affecting Fetus or Newborn
Foley With Oxytocin Versus Foley no Oxytocin for Induction of Labor
The overall purpose of this study is to determine if adding oxytocin to a Foley catheter for induction of labor will increase the rate of delivery within 24 hours stratified by parity.
- Trial name
- NOFOX (NCT02273115)
- Testing
- Oxytocin, Transcervical Foley catheter
- Where
- 2 sites in United States
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Fetal Membranes, Premature Rupture, Labor, Induced/IS
Foley Catheter for Labor Induction in Women With Term and Near Term Membrane Rupture
In women undergoing labor induction for membrane rupture at or near term, we are investigating the addition of a foley catheter placed in the cervix to standard therapy (oxytocin administration) to decrease the time from the…
- Trial name
- NCT00290199
- Testing
- Transcervical Foley catheter
- Where
- 3 sites in United States
- Volunteers
- 169 people
- Sponsor
- University of Alabama at Birmingham
Pregnancy, Labor, Induced
Study of Ultrasound Imaging to Predict Time and Outcome in Pregnancies With Induced Labor
The aim of the study was to evaluate any possible associations between engagement and position of the fetal head and the outcome of labor in women with induced labor, and to compare the value of ultrasound measurements in…
- Trial name
- NCT00465998
- Where
- Norway
- Volunteers
- 250 people
- Sponsor
- Helse Stavanger HF
Cervical Ripening, Labor, Induced
Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor
The purpose of this study is to determine whether the misoprostol vaginal insert (50 mcg and 100 mcg) can safely and effectively speed time to vaginal delivery compared to Cervidil (R) in women who need to have cervical ripneing…
- Trial name
- NCT00308711
- Testing
- Misoprostol vaginal insert 100 mcg, Misoprostol vaginal insert 50 mcg, Dinoprostone vaginal insert (Cervidil)
- Where
- 52 sites in United States, Canada
- Volunteers
- 1,308 people
- Sponsor
- Ferring Pharmaceuticals