Clinical trials: LSG
Vomiting, Postoperative
Staple Line Inversion vs Buttressing on Postoperative Vomits After LSG
Patients undergoing laparoscopic sleeve gastrectomy will be randomized into 2 groups. In one group, a staple line inversion with a running suture of Polypropylene will be performed.
- Trial name
- NCT03104023
- Testing
- Staple line inversion, Staple line buttressing
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital General Universitario Elche
Non-alcoholic Steatohepatitis (NASH)
Efficacy and Safety of Endoscopic Sleeve Gastroplasty Versus Laparoscopic Sleeve Gastrectomy in Obese Subjects With NASH
The primary objectives of this study are to evaluate the effect of ESG with OverStitch® system (Apollo Endosurgery, Austin, TX, USA) compared to LSG on 1) histological improvement in NASH; 2) all-cause mortality and liver-related…
- Trial name
- TESLA-NASH (NCT04060368)
- Testing
- Endoscopic Sleeve Gastroplasty (ESG) with OverStitch® system + Lifestyle modifications, Laparoscopic Sleeve Gastrectomy (LSG) + Lifestyle modifications
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Sleeve Gastrectomy
Powered Handle Primary Sleeve Gastrectomy Study
The objective of this prospective, single arm, single-center study is to evaluate patients who are undergoing primary sleeve gastrectomy procedures and are surgically treated with the AEON Endoscopic Powered Handle Stapler and…
- Trial name
- NCT06474637
- Testing
- AEON Endoscopic Powered Stapler Handle and Reload
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lexington Medical Inc.
Morbid Obesity
Laparoscopic Gastric Bypass Versus Sleeve Gastrectomy to Treat Morbid Obesity
Bariatric surgery in the treatment of morbid obesity is associated with long-term weight-loss and decreased overall mortality. Long-term results have been reported for laparoscopic gastric bypass procedures but the long-term…
- Trial name
- SLEEVEPASS (NCT00793143)
- Where
- 4 sites in Finland
- Volunteers
- 240 people
- Sponsor
- Turku University Hospital
Diabetes Mellitus
Diabetes Resolution and Hormone Changes After BPDLL and LSG
To evaluate and compare prospectively the effects of Biliopancreatic Diversion Long Limb (BPDLL) and Laparoscopic Sleeve Gastrectomy (LSG) on resolution of diabetes mellitus type 2.
- Trial name
- NCT01481675
- Where
- 2 sites in Greece
- Volunteers
- 24 people
- Sponsor
- University of Patras
To Compare the Difference of AHI Variation Between LSG and Combined Surgery
Effects of Combined Surgery on Obstructive Sleep Apnea in Obese Patients: an Open-label Randomized Controlled Clinical Trial
This research is created for compare the difference of AHI variation between LSG and combined surgery on obstructive sleep apnea in obese patients , evaluate the risk of combined surgery and explore the correlative factor of the…
- Trial name
- NCT03227939
- Testing
- Laparoscopic sleeve gastrectomy（LSG）, Uvulopalatopharyngoplasty(UPPP) and Adenoidectomy/Tonsillectomy
- Volunteers
- 100 people
- Sponsor
- Bing Wang
Obesity, Morbid, Hernia Incisional
TROCAR SITE HERNIA AFTER LSG
Today, laparoscopic sleeve gastrectomy (LSG) has become the most frequently performed bariatric surgical method. One of the complications seen after LSG is trocar site hernia (TSH).
- Trial name
- NCT04849403
- Testing
- CTSP
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Obesity, Childhood, Bariatric Surgery Candidate
Long-Term Outcomes of LSG in Pediatric Patients
This project aims to assess the short- and long-term safety and efficacy of bariatric surgery in children and adolescents compared to adults.
- Conditions
- Obesity, Childhood, Bariatric Surgery Candidate, Cardiovascular Risk Factor
- Trial name
- NCT04136704
- Testing
- Sleeve gastrectomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Saud University
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
GERD, Bariatric Surgery
Endoscopic Cardiac Band Ligation for the Management of Refractory GERD After Laparoscopic Sleeve Gastrectomy
GERD is a prevalent condition worldwide, estimated to be around 20-30 % in North America. Obesity is rapidly increasing with an estimated prevalence of 66% in the adult population in the United States.
- Conditions
- GERD, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy
- Trial name
- CLEAR (NCT04771247)
- Testing
- Cardia Band Ligation
- Sponsor
- Johns Hopkins University
Laparoscopic Sleeve Gastrectomy (LSG), Erector Spinae Plane Block
Comparing Perioperative Analgesia After Ultrasound Guided Bilateral Erector Spinae Plane Block and Thoracic Paravertebral Block in Laparoscopic Sleeve Gastrectomy Patients
The aim of this study is to compare the efficacy of ultrasound-guided bilateral erector spinae plane block and thoracic paravertebral block on perioperative analgesic control for 24 hours postoperative and fast recovery of…
- Conditions
- Laparoscopic Sleeve Gastrectomy (LSG), Erector Spinae Plane Block, Thoracic Paravertebral Block
- Trial name
- NCT06798103
- Testing
- Erector Spinae Plane Block, Thoracic paravertebral block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Endoscopic Sleeve Gastroplasty, Laparoscopic Sleeve Gastrectomy
ESG vs LSG: Short-term Nutritional Outcomes
To assess endoscopic sleeve gastroplasty in comparison to laparoscopic sleeve gastrectomy before and 3 months after the procedure in terms of multiple nutrition-related factors, quality of life, weight and other related…
- Conditions
- Endoscopic Sleeve Gastroplasty, Laparoscopic Sleeve Gastrectomy, Obesity
- Trial name
- NCT04264364
- Testing
- Laparoscopic sleeve gastrectomy, Endoscopic sleeve gastroplasty
- Where
- Saudi Arabia
- Volunteers
- 57 people
- Sponsor
- King Saud University
Obesity, Postoperative Pain
Pregabalin in the Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy (LSG).
The aim of this clinical trial is to assess preemptive oral pregabalin administration in the obese patients undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Obesity, Postoperative Pain, Postoperative Nausea and Vomiting, Opioid Use
- Trial name
- NCT05804591
- Testing
- Pregabalin 150mg
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Warsaw
Pain, Postoperative, Obesity, Morbid
Effect of Bilateral Rectointercostal Fascial Plane Block on Postoperative Pain After Laparoscopic Sleeve Gastrectomy
This randomized controlled study aims to evaluate the effectiveness of the bilateral rectointercostal fascial plane (RIB) block for postoperative pain management in patients undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Pain, Postoperative, Obesity, Morbid, Laparoscopic Sleeve Gastrectomy (LSG), Opioid Use
- Trial name
- NCT07253610
- Testing
- Bilateral Rectointercostal Fascial Plane Block, Intravenous Patient-Controlled Analgesia (IV PCA) with Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Samsun University
Obesity, Morbid, Bariatric Surgery Candidate
Comparison of the Effect of Traditional Method and Eras Protocol in Obesity Surgery
This study was conducted to compare the effectiveness of care based on the "Accelerated Recovery After Surgery (ERAS) Protocol" and the traditional method in bariatric surgery and demonstrate the difference the two methods based…
- Conditions
- Obesity, Morbid, Bariatric Surgery Candidate, Obesity Adult Onset, Obesity Associated Disorder
- Trial name
- NCT05790317
- Testing
- Surgical Procedure with ERAS Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
GERD, Gastroesophageal Reflux Disease
RELIEF Europe Study
The purpose of this study is to evaluate the LINX device in patients who have previously undergone laparoscopic sleeve gastrectomy (LSG) for obesity and have chronic gastroesophageal reflux disease (GERD).
- Conditions
- GERD, Gastroesophageal Reflux Disease, Obesity, LSG
- Trial name
- NCT02762487
- Testing
- The LINX® Reflux Management System
- Where
- 4 sites in Germany, Italy
- Volunteers
- 7 people
- Sponsor
- Torax Medical Incorporated
GERD, Gastroesophageal Reflux Disease
LINX Reflux Management System in Subjects With GERD Who Have Previously Undergone a Laparoscopic Sleeve Gastrectomy
The purpose of this study is to evaluate the LINX device in patients who have previously undergone laparoscopic sleeve gastrectomy (LSG) for obesity and have chronic gastroesophageal reflux disease (GERD).
- Trial name
- RELIEF (NCT02429830)
- Testing
- LINX device
- Where
- 12 sites in United States
- Volunteers
- 30 people
- Sponsor
- Torax Medical Incorporated
Laparoscopic Sleeve Gastrectomy (LSG), Thoracic Lung Resection Procedure
A Study of ECHELON 3000 (Next Generation Powered Stapler) in General Abdominal and Thoracic Lung Resection Procedures
The purpose of this study is to assess the safety and performance of the ECHELON 3000 Stapler (next generation powered stapler) and reload system in participants undergoing laparoscopic sleeve gastrectomy or lung resection…
- Trial name
- NCT05519215
- Testing
- ECHELON 3000 Stapler
- Where
- 8 sites in United States
- Volunteers
- 244 people
- Sponsor
- Ethicon Endo-Surgery
GERD
Study Comparing the Effect of Ligamentum Teres Cardiopexy on de Novo GERD Post LSG
The aim of this study is to investigate the effect of ligamentum teres cardiopexy on incidence of de Novo GERD.
- Trial name
- NCT04652336
- Testing
- laparoscopic sleeve gastrectomy, ligamentum teres cardiopexy with sleeve gastrectomy
- Volunteers
- 100 people
- Sponsor
- GEM Hospital & Research Center
Excision Margin
Incidental Finding of Gastrointestinal Stromal Tumors (GISTs) During Laparoscopic Sleeve Gastrectomy, How to Deal? How Much Safety Margin
LSG is thought to be the best choice for obese patients with conincidental GISTs, as a tumour can be resected along with resecting the stomach within the same procedure.
- Trial name
- NCT04344847
- Testing
- Laparoscopic sleeve gastrectomy
- Where
- Saudi Arabia
- Volunteers
- 338 people
- Sponsor
- Bassem Mohamed Sieda