Clinical trials: Kratom Pharmacodynamics
Kratom Pharmacokinetics, Kratom Pharmacodynamics
Direct Observation Study of Kratom Product Effects Among Regular Consumers
The goal of this observational clinical study is to is to learn more about how commercial kratom products affect healthy adults who consume them regularly. The main questions it aims to answer are: 1.
- Conditions
- Kratom Pharmacokinetics, Kratom Pharmacodynamics, Kratom
- Trial name
- NCT06089980
- Testing
- Effects from acute kratom exposure
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Safety, Pharmacokinetics
Single Ascending Doses of Kratom in Healthy Nondependent Adults With Opioid Experience
Kratom (Mitragyna speciosa) is a plant often used to self-treat conditions such as pain, coughing, diarrhea, anxiety and depression, opioid use disorder, and opioid withdrawal.
- Conditions
- Safety, Pharmacokinetics, Pharmacodynamics
- Trial name
- NCT06072170
- Testing
- Kratom
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Altasciences Company Inc.
Kratom Pharmacodynamics, Kratom Pharmacokinetics
Preliminary Characterization of Commercial Kratom Extract Products
To understand the acute subjective, physiological, and cognitive effects of commercial kratom extract products among US adults who consume these products regularly, and to understand how these products are metabolized by the…
- Trial name
- NCT06640569
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Herbal Interaction
Evaluating a Potential Pharmacokinetic Kratom-oxycodone Interaction Concurrent With Clinical Endpoints
The goal of this study is to investigate whether the botanical product kratom affects how the body processes the opioid drug oxycodone. The main research questions to be answered are two-fold: 1.
- Trial name
- NCT05846451
- Testing
- Kratom, Oxycodone
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Washington State University