Clinical trials: Knee Swelling Pain
Total Knee Replacement
Influence of Manual Lymph Drainage During Hospitalization on Swelling, Function and Pain in Patients After Total Knee Replacement
To investigate the effects of lymphatic drainage massage performed immediately after total knee replacement in relation to reduction of limb circumference, pain reduction and functional improvement.
- Trial name
- NCT01657149
- Testing
- Lymphatic massage and individual physiotherapy, individual physiotherapy only
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Rabin Medical Center
Knee Osteoarthritis, Knee Arthritis
Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity
- Trial name
- NCT04234282
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jennifer Moreno Clinic
Medial Compartment Osteoarthritis of the Knee
High Tibial Osteotomy (HTO) With or Without Arthroscopy of the Knee Joint
Participants will be randomized to undergo a High Tibial Osteotomy (HTO) with or without a knee scope. Patients will be tested in the Gait Lab, will fill out quality-of-life questionnaires, and have a clinical evaluation done…
- Trial name
- NCT01614288
- Testing
- knee Arthroscopy, No arthroscopy
- Where
- Canada
- Sponsor
- University of Western Ontario, Canada
Knee Pain Swelling
Painful Total Knee Replacement (TKA) and I-one Therapy
Arthroplasty operations are very frequent and their number is constantly increasing. The success of prosthetic surgery is linked to surgical factors (prosthesis type, prosthesis design, prosthesis material, surgical hand) and…
- Trial name
- NCT06330454
- Testing
- I-ONE
- Where
- 7 sites in Italy
- Volunteers
- 237 people
- Sponsor
- University Hospital of Ferrara
Osteo Arthritis Knee, Knee Osteoarthritis
Knee Arthritis Treatment With Autologous Fragmented Adipose Tissue and PRP - Comparison of Two Treatment Methods
This is a prospective, randomized, controlled study. The purpose of this study is to assess functional and clinical changes among patients with symptomatic knee OA treated with intra-articular injections of autologous adipose…
- Conditions
- Osteo Arthritis Knee, Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT04321629
- Testing
- autologous adipose tissue transfer, PRP injections
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Rehasport Clinic
Knee Osteoarthritis, Knee Pain Chronic
Genicular Artery Embolization (GAE) for Osteoarthritic Knee Pain
The objective of this investigation is to evaluate the safety of the geniculate artery embolization (GAE) procedure with HydroPearl® Microspheres in 30 patients with knee pain caused by osteoarthritis with 24 months follow-up.
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Pain Swelling, Knee Arthritis
- Trial name
- NCT04472091
- Testing
- Genicular artery embolization (GAE)
- Where
- United States
- Sponsor
- Andrew Picel
Knee Pain Chronic, Knee Swelling Pain
Genicular Artery Embolization (GAE) for the Treatment of Chronic Post Knee Arthroplasty Pain
This study seeks to evaluate the safety and efficacy of genicular artery embolization (GAE) as a treatment for patients with chronic pain following primary total knee arthroplasty (TKA) or revision TKA at 6 months as measured by…
- Conditions
- Knee Pain Chronic, Knee Swelling Pain, Arterial Occlusion
- Trial name
- NCT05248308
- Testing
- Embozene Microspheres
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Foreign-Body Reaction, Inflammation
IMPACT: Safety and Feasibility of a Single-stage Procedure for Focal Cartilage Lesions of the Knee.
Articular cartilage defects in the knee have a poor intrinsic healing capacity and may lead to functional disability and osteoarthritis.
- Conditions
- Foreign-Body Reaction, Inflammation, Effusion (L) Knee, Knee Pain Swelling
- Trial name
- IMPACT (NCT02037204)
- Testing
- Cartilage repair surgery
- Where
- Netherlands
- Volunteers
- 35 people
- Sponsor
- UMC Utrecht
Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear
Clinical Efficacy of Exosome in Degenerative Meniscal Injury
Comparison of intra-articular administration of synovial fluid-derived mesenchymal stem cells-derived exosomes with synovial fluid-derived mesenchymal stem cells on the same patient.
- Conditions
- Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear, Meniscus Lesion, Meniscus; Degeneration
- Trial name
- KNEEXO (NCT05261360)
- Testing
- SF-MSC-EX, SF-MSC
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
Osteoarthritis, Knee, Osteoarthritis
A Study of the Feasibility of Using the Dietary Supplement "ARTNEO" in Patients With Osteoathritis
The goal of this clinical study is to evaluate the effectiveness of the properties that support the functional state of the joints and the safety of the dietary supplement for food ARTNEO®, oral capsules, in patients with stage…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT05975879
- Testing
- undenaturated collagen type II, methylsulfonylmethane, boswellia serrata, vitamin D3 (cholecalciferol), vitamin C (ARTNEO)
- Where
- 12 sites in Russia
- Volunteers
- 212 people
- Sponsor
- NPO Petrovax
Knee Osteoarthritis (OA)
Clinical Study on the Combination of Xiaoyu Zhitong Formula and Lymphatic Drainage Technique to Improve the Symptoms of Knee Pain and Swelling in Cold Dampness Obstruction Type
This research project applies a combination of blood stasis relieving and pain relieving formula and lymphatic drainage technique to treat patients with cold dampness obstruction type knee joint pain.
- Trial name
- NCT06911437
- Testing
- treatment group, control group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- tang jie
Total Knee Arthroplasty Recovery
Effects of Progressive Restricted Blood Flow Exercises in Post Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a commonly performed procedure for advanced knee osteoarthritis. Despite successful surgery, many patients experience postoperative impairments including pain, reduced range of motion (ROM)…
- Trial name
- TKA PBFR (NCT07601906)
- Testing
- Blood Flow Restriction Exercises and Conventional Physical Therapy, Conventional Physical Therapy alone
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Knee Osteoarthritis, Knee Discomfort
IMAGES: Identifying Metabolic Imaging Association With Genicular Artery Embolization Success
Several clinical trials on genicular artery embolization (GAE) show significant clinical benefit for the majority of patients. However, a proportion of patients do not benefit from GAE, and responses vary across individual…
- Conditions
- Knee Osteoarthritis, Knee Discomfort, Knee Pain Chronic, Knee Swelling Pain
- Trial name
- NCT07494838
- Testing
- Embolization
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Lucas R. Cusumano, MD
Degenerative Disease, Meniscus Tear
The Open Kinetic Chain and Closed Kinetic Chain Strengthening Exercises in Degenerative Meniscus Tears
This randomized-controlled trial aims to compare the effect of open kinetic chain and closed kinetic chain strengthening exercises on pain, function, and health-related quality of life in degenerative meniscus tears.
- Conditions
- Degenerative Disease, Meniscus Tear, Knee Pain Swelling
- Trial name
- NCT06447142
- Testing
- Open kinetic chain strengthening exercise, Closed kinetic chain strengthening exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Edema
Effect of Compression Therapy on Postoperative Swelling and Pain After Total Knee Arthroplasty
The number of severely obese patients who has knee replacement surgery is rising. Obesity increases the risk of the postoperative swelling.
- Trial name
- NCT03490409
- Testing
- Thigh compression stocking
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Naestved Hospital
Osteoarthritis
To Study Generic Diclofenac Sodium Topical Gel 1% in the Treatment of Osteoarthritis of the Knee (Degenerative Joint Disease Presented as Joint Pain, Stiffness, Swelling and Restricted Motion).
This is a Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Multiple-Site Clinical Study to Evaluate the Therapeutic Equivalence of Diclofenac Sodium Gel, 1% (Glenmark Pharmaceuticals Ltd) to Voltaren® Gel…
- Trial name
- NCT02596451
- Testing
- Diclofenac Sodium gel, 1%, Voltaren® Gel
- Where
- 44 sites in United States
- Volunteers
- 1,164 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Total Knee Arthroplasty, Venous Insufficiency of Leg
Efficacy of Diosmin and Hesperidin on Early Rehabilitation After Total Knee Arthroplasty
The goal of this clinical trial is to find out the efficacy of diosmin and hesperidin on postoperative early rehabilitation after primary total knee arthroplasty.
- Trial name
- NCT06753448
- Testing
- Diosmin and Hesperidin Combination
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people
- Sponsor
- Ankara Etlik City Hospital
Blood Loss
Fibrin Sealant in Bilateral Simultaneous Total Knee Arthroplasty With Focus on Blood Loss, Pain, Swelling and Strength
The purpose of this study is to measure the effect of fibrin sealant on reducing blood loss, pain and swelling when operated for bilateral total knee arthroplasty.
- Trial name
- NCT01472913
- Testing
- Fibrin sealant, Saline water
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Osteoarthritis of Knee, Edema
Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery
The purpose of this study is to determine if patients undergoing a total knee arthroplasty (TKA) experience a clinically significant reduction in healing time when treated post operatively with a specific form of micro and…
- Conditions
- Osteoarthritis of Knee, Edema, Wounds and Injuries
- Trial name
- NCT02623660
- Testing
- ODIN1, Standard Care, Diagnostic Device Testing
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bioelectric Research Corporation
Knee Pain Swelling
Knee Swelling Under Use of Compression Stockings After Outpatient Surgery
Outpatients who undergo knee surgery are designated two different clinical study groups. Group A receives common wrapping after surgery to the first postsurgical day and will be provided with compression stockings for the…
- Trial name
- NCT02096562
- Testing
- Patients use compression stockings for 10 days after surgery, normal therapy - no compression stockings
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- University of Rostock