Clinical trials: Knee Joint Function
Osteoarthritis, Knee
An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect
In this proposal, we plan to dynamically investigate brain response to verum acupuncture (of two different "doses") and placebo acupuncture, using a paradigm that approximates clinical acupuncture practice across multiple…
- Trial name
- NCT01079390
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Massachusetts General Hospital
Pes Anserine Bursitis
Comparison of Bracing and Eccentric Loading Exercises on Pain Modulation and Functional Improvement in Acute Pes Anserine Bursitis Patients
This study aims to compare the effects of knee bracing and eccentric loading exercises on pain and functional ability in adults with acute pes anserine bursitis.
- Trial name
- NCT07881913
- Testing
- Medial-Support Knee Brace, Eccentric Loading Exercise
- Where
- 2 sites in Pakistan
- Volunteers
- 32 people
- Sponsor
- Dr Aneeqa Sultan
Arthroplasty, Overweight and Obesity
Healthy Living After Knee Replacement
The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to…
- Trial name
- NCT05190666
- Testing
- PACE Weight Loss program, Chronic Disease Self-Management
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Total Knee Arthroplasty, Total Knee Replacement
Assessing Function and Pain After Total Knee Arthroplasty With Combined Femoral and Popliteal Nerve Block
The goal of this interventional study is to examine whether a pain management technique of combined femoral and popliteal nerve block is effective in total knee arthroplasty patients.
- Conditions
- Total Knee Arthroplasty, Total Knee Replacement, Total Knee Replacement Surgery, Arthritis Knee
- Trial name
- NCT06196359
- Testing
- Combined Femoral and Popliteal nerve block
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- University of Haifa
Anterior Knee Pain Syndrome, Patellofemoral Pain Syndrome
The Immediate Effects of Passive Hip Joint Mobilization on Hip Muscle Strength in Patients With Anterior Knee Pain
The aim of the study is to assess the immediate effects of passive hip joint mobilisation (in comparison to a sham mobilisation) on eccentric hip abductor/external rotator muscle strength on the basis of manual muscle testing…
- Trial name
- NCT03771495
- Testing
- Joint Mobilization, Laying on of Hands
- Where
- Austria
- Volunteers
- 18 people
- Sponsor
- Sheffield Hallam University
Knee Osteoarthritis
Kinesiophobia, Pain, Functional Status and Self-Efficacy in Patients With Knee Osteoarthritis
Objective: The aim of this study is to examine the relationship between kinesiophobia, pain, functional status and self efficacy in patients with knee osteoarthritis.
- Trial name
- NCT05036551
- Testing
- Kellgren Lawrence classification
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hacettepe University
Knee Osteoarthritis, Genicular Nerve Block
Phenol Neurolysis Versus Local Anesthetic Plus Steroid Genicular Nerve Block in Knee Osteoarthritis
This study aims to evaluate two different ultrasound-guided procedures for patients with knee osteoarthritis (gonarthrosis) who did not benefit from conservative treatments.
- Trial name
- NCT07267039
- Testing
- Phenol Injection, Bupivacaine + Triamcinolone Acetonide Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Salim Sencar
Patellar Instability
Computational Simulation of Patellar Instability
Computational simulation will be performed to represent motion of knees with a dislocating kneecap. Common surgical treatment methods will be simulated and anatomical parameters commonly associated with the dislocation will be…
- Trial name
- NCT02998372
- Testing
- patellar stabilization
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Cleveland Clinic Akron General
Knee Osteoarthritis
Comparison of Functional Outcomes of Three Surgical Approaches in Knee Arthroplasty
A functional outcomes comparison study of three surgical techniques using minimally invasive surgery mini-incision (MIS) for total knee arthroplasty (TKA), standard para-patellar TKA and the unicompartmental knee arthroplasty…
- Trial name
- NCT00983762
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoarthritis of the Knee, Coagulopathy
Trial to See if Topical Pennsaid for Knee Pain Affects Coagulation Values in Patients Who Are Also Taking Anticoagulants
The purpose of this study is to see if using a topical nonsteroidal antiinflammatory drug (Pennsaid) to treat osteoarthritis knee pain will affect coagulation values in patients who are also taking anticoagulant or antithrombotic…
- Trial name
- ATCCTCP-1 (NCT01511939)
- Testing
- Pennsaid
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Nathan Wei, MD, FACP, FACR:
Arthrosis of the Knee
Study on Personalized Total Knee Arthroplasty (TKA) Rehabilitation Using Telemedicine and Psychoeducation
The aim of this clinical study is to evaluate the effectiveness of a telemedicine approach in improving treatment adherence and functional outcomes in patients recently underwent total knee replacement for primary osteoarthritis.
- Trial name
- TKA (NCT07032805)
- Testing
- personalized outpatient rehabilitation treatment after TKA, standard outpatient rehabilitation treatment after TKA
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Laura Belinda Rizzo
Total Knee Arthroplasty (TKA)
Total Knee Arthroplasty Biomechanics
In total knee arthroplasty (TKA), the relationship between implant design, soft tissue balance, neuromuscular contributions, and rehabilitation strategies on patient satisfaction and functional outcomes is highly complex and…
- Trial name
- NCT03671954
- Testing
- Home Strengthening Exercises, Standard Physical Therapy, Preoperative Assessments
- Where
- 4 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Florida
Osteoarthritis Knee
Effect of Mesenchymal Stem Cells in Primary Knee Osteoarthritis
Osteoarthritis (OA) is the most prevalent chronic joint disorder worldwide and is associated with significant pain and disability. Incidence and prevalence of osteoarthritis rise with increasing age.
- Trial name
- NCT05783154
- Testing
- Autologous Adipose Tissue-Derived Mesenchymal Stem Cell
- Where
- Bangladesh
- Volunteers
- 84 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Knee Osteoarthritis
ADDITIVE BENEFITS of KALTENBORN SUSTAINED STRETCH JOINT MOBILIZATION with RESISTANCE EXERCISE TRAINING in KNEE OSTEOARTHRITIS
to determine the supplementary effects of Kaltenborn sustained stretch mobilization when combined with resistance training in the management of knee osteoarthritis.
- Trial name
- NCT06211387
- Testing
- Resistance Exercise Training, Joint Mobilization
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Foundation University Islamabad
Osteoarthritis, Knee
Outcome Following Hylan F- 20 (Synvisc) + Corticosteroid Injections for the Treatment of Osteoarthritis of the Knee
The goal of viscosupplementation is to replenish synovial fluid, which will improve patient symptoms and mobility. Viscosupplementation of the knee with hyaluronic acid injections has been shown to improve symptoms in patients…
- Trial name
- NCT00312533
- Testing
- Hylan F- 20
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Steadman Hawkins Research Foundation
Osteoarthritis, Knee
Cryotherapy Effectiveness in Individuals With End Stage Knee Osteoarthritis - a Case Series
The purpose of this case series will be to provide a detailed description of a standardized short-term cryotherapy application protocol using validated functional outcome measures in individuals with end stage KOA
- Trial name
- NCT03582644
- Testing
- Cryotherapy
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Universidade Federal de Sao Carlos
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Vibration on Patellofemoral Joint Pain After ACLR
Anterior cruciate ligament (ACL) injury is a prevailing problem among sports participants, especially in non-contact sports. Studies have reported that 70-84% of ACL injuries are non-contact in nature, and movements like changing…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Patellofemoral Pain
- Trial name
- NCT05501210
- Testing
- WBV, PEMF
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis
Effects of Shock Absorbing Insoles on Knee Pain and Walking in Persons With Knee Osteoarthritis
Osteoarthritis (OA) is a progressive, chronic disease affecting more than 20 million Americans. There is no known cure for OA and management includes pain control and prevention of functional decline.
- Trial name
- NCT02018380
- Testing
- Shock Absorbing Insole (SofSole Athletes Plus)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Winston Salem State University
Knee Osteoarthritis, Arthropathy of Knee Joint
Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia
Previous retrospective database studies suggest that total knee arthroplasty (TKA) surgery under spinal anesthesia has less complications than when performed under general anesthesia.
- Conditions
- Knee Osteoarthritis, Arthropathy of Knee Joint, Knee Pain Chronic, Rheumatoid Arthritis
- Trial name
- NCT03364088
- Testing
- Spinal anesthesia with tourniquet, Spinal anesthesia without tourniquet, General anesthesia with tourniquet
- Where
- Finland
- Volunteers
- 402 people
- Sponsor
- Riku Antero Palanne
Knee Osteoarthritis
Effect of Retro Walking Versus Isometric Multi-angular Exercises on Pain and Functional Performance in Knee Osteoarthritis in Geriatric Population
Osteoarthritis is a leading musculoskeletal cause of disability in elderly persons all over the world and a major cause of physical limitations and reduced quality of life (1).
- Trial name
- NCT06274346
- Testing
- Multiangular Isometric exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology