Clinical trials: Knee Cartilage Lesions, open to volunteers
Knee Injuries, Joint Surface Knee Lesions
A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee
The purpose of the study is to support market adoption and global market access via collection of long-term effectiveness, safety, and radiographic data.
- Trial name
- NCT06916728
- Testing
- Marketed Product - MP01, Surgical Standard of Care
- Where
- 8 sites in United States, Belgium and 4 more
- Volunteers
- 170 people
- Sponsor
- Smith & Nephew, Inc.
Focal Cartilage Lesions of the Knee
Management of Focal Cartilage Lesions of the Knee: The Benefits of an Autograft Procedure
Cartilage is a tissue whose primary function is to transmit and distribute loads when joints are under stress. It acts as a buffer between bones at the joints.
- Trial name
- CART-MCI Knee (NCT07641868)
- Testing
- Management of focal cartilage lesions of the knee: micro-fracture, Minced Cartilage Implantation (MCI)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Louis Pasteur Santé Lorraine
Knee Pain Chronic, Knee Osteoarthritis
BioPoly® Partial Resurfacing Knee Implant IDE
The goal of this randomized controlled clinical trial is to demonstrate the safety and effectiveness of the BioPoly® Partial Resurfacing Knee Implant for the treatment of cartilage defects of the distal femur in adult patients…
- Conditions
- Knee Pain Chronic, Knee Osteoarthritis, Cartilage Damage, Cartilage Defects of the Knee
- Trial name
- NCT06915363
- Testing
- BioPoly, surgical standard of care (SSOC)
- Where
- 5 sites in United States
- Volunteers
- 152 people
- Sponsor
- BioPoly LLC
Knee Cartilage Defects
Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis
This study will test whether CARTISTEM is safe and works better than debridement (a surgery that cleans out damaged tissue) for people with knee cartilage damage and osteoarthritis.
- Trial name
- CARTISTEM23-01 (NCT07339111)
- Testing
- CARTISTEM® + Debridement, Debridement
- Where
- 37 sites in United States
- Volunteers
- 300 people
- Sponsor
- Medipost, Inc.
Knee Cartilage Lesions
Nanochon Chondrograft First in Human (FIH) Early Feasibility Study (EFS) - Canada
The goal of this First in Human study is to learn if the Nanochon Chondrograft Implant is a safe primary surgical treatment for participants with cartilage lesions in the knee.
- Trial name
- NCT07249489
- Testing
- Nanochon Chondrograft
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- Nanochon, Inc.
Bone Lesion, Cartilage Degeneration
Efficacy of Bioceramic Materials for Bone Defects Repair
The purpose of this study is to demonstrate the effect of bioceramic implants on the repair of human bone defects, and to explore the application of bioceramic materials in bone defects, bone implantation, and bone fusion.
- Conditions
- Bone Lesion, Cartilage Degeneration, Osteo Arthritis Knee, Bone Fracture
- Trial name
- NCT06249906
- Testing
- Commercial bone implant product Group, Mirco-structured Bioceramic Group
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Knee Injuries, Joint Surface Knee Lesions
Knee Cartilage Repair Registry
This registry is designed to collect information on how different surgical procedures are used and how well they work in treating knee cartilage damage.
- Trial name
- C-SHORE (NCT07786207)
- Testing
- Marketed Product - MP01, Other Surgical Treatments
- Where
- 6 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Smith & Nephew, Inc.
Lipedema, Knee Osteoarthritis
The Effect of Lipedema on Knee Osteoarthritis
This study will be one of the few to examine the effect of lipedema on knee osteoarthritis in a comparative manner with a control group within the same osteoarthritis context.
- Conditions
- Lipedema, Knee Osteoarthritis, Knee Acute and Chronic Pain, Knee
- Trial name
- NCT07575555
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Izmir Democracy University
Knee Cartilage Lesions
Nanochon Chondrograft First in Human (FIH) Early Feasibility Study (EFS) - Panama
The goal of this First in Human study is to learn if the Nanochon Chondrograft Implant is a safe primary surgical treatment for participants with cartilage lesions in the knee.
- Trial name
- NCT07542184
- Testing
- Nanochon Chondrograft
- Where
- Panama
- Volunteers
- 5 people
- Sponsor
- Nanochon, Inc.
Chondral Lesion of the Knee, Meniscal Injuries
Impact of Bone-Marrow Aspirate Injections in Knee Arthroscopy
This study will examine whether using bone marrow aspirate (BMA) during knee arthroscopy surgery can improve patient outcomes. The investigators will enroll 50 patients who need knee arthroscopy surgery for meniscus injuries or…
- Conditions
- Chondral Lesion of the Knee, Meniscal Injuries, Cartilage Defects of the Knee, Osteoarthritis (OA) of the Knee
- Trial name
- BMA (NCT06893302)
- Testing
- Bone Marrow Aspirate (BMA), Arthroscopic Debridement Surgery, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Cartilage Lesion
Effectiveness and Safety of Knee Cartilage Lesion Treatment Using CartiONE: 1-to-13 Year Follow-up.
CartiONE is a technique used in autologous articular-chondrocyte-based treatments for symptomatic focal articular-cartilage lesions of the knee.
- Trial name
- ICONIC (NCT06809231)
- Where
- 5 sites in Belgium, Poland and 1 more
- Volunteers
- 100 people
- Sponsor
- Cartilage Repair Systems BV