Clinical trials: Kidney Transplant Candidates
Latent Tuberculosis, End Stage Renal Disease
One-month Latent Tuberculosis Treatment for Renal Transplant Candidates
This is a prospective, single-center, single-arm, open-label study investigating the safety, compliance and pharmacokinetics of 1-month treatment of Isoniazid, Rifapentine and Vitamin B6 in renal transplant candidates.
- Conditions
- Latent Tuberculosis, End Stage Renal Disease, Renal Transplant Candidate for Right Kidney, Renal Transplant Candidate for Left Kidney
- Trial name
- NCT05411744
- Testing
- 1 month Rifapentine, Isoniazid and Vitamin B6
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
End Stage Renal Disease, Kidney Transplantation
Desensitization of Renal Transplant Candidates
Trial of the use of Myfortic to reduce anti-HLA alloantibody in patients waiting for renal transplantation.
- Trial name
- NCT00298883
- Testing
- Myfortic
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Florida
Kidney Failure, Chronic, Frailty
Evolution of Physical Frailty and Patient-Reported Outcome Measures in Kidney Transplant Candidates: A Mixed-Methods Longitudinal Study Protocol
This study looks at how the physical and emotional health of people changes while they wait for a kidney transplant. Waiting for an organ can take a long time.
- Conditions
- Kidney Failure, Chronic, Frailty, Quality of Life, Kidney Transplantation
- Trial name
- NCT07607041
- Testing
- Longitudinal Frailty Assessment, Electronic Patient-Reported Outcome Measures (ePROMs)
- Volunteers
- 150 people
- Sponsor
- Hospital del Mar
Frailty, Kidney Transplant; Complications
Frailty Assessment Among Kidney Transplant Candidates
Frailty is common among chronic kidney disease patients who are on the kidney transplant (KT) waiting list. The aim of this study is to assess frailty according to different frailty tools among KT candidates and to establish…
- Trial name
- Mar-Kid (NCT04811417)
- Volunteers
- 500 people
- Sponsor
- Parc de Salut Mar
End Stage Liver Disease, End Stage Renal Disease
Transplant and Addiction Project (TAP) - 1
The purpose of this study is to test a novel distance-based (telephone) intervention to help transplant candidates with current or recent substance abuse to stay "clean and sober" both prior and following transplant surgery.
- Conditions
- End Stage Liver Disease, End Stage Renal Disease, Substance-Related Disorders
- Trial name
- NCT00249652
- Testing
- TAP, TAU
- Where
- 3 sites in United States
- Volunteers
- 41 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
HHV8, HHV8 Infection
HHV8 and Solid Organ Transplantation
Solid organ transplant candidates will undergo serological screening for HHV8 at time of listing and transplantation. In the event of a recipient/donor mismatch R-/D+ or in the presence of a seropositive recipient (R+), blood…
- Conditions
- HHV8, HHV8 Infection, HHV8-Related Malignant Neoplasm, Kaposi Sarcoma
- Trial name
- NCT05081141
- Testing
- Diagnostic test for HHV8 exposure
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Chronic Kidney Disease 5D, Chronic Kidney Disease Stage 5
Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant.
- Conditions
- Chronic Kidney Disease 5D, Chronic Kidney Disease Stage 5, Kidney Failure, Kidney Failure,Chronic
- Trial name
- KINETIC (NCT07446296)
- Testing
- Exercise Rehabilitation Program with Physical Activity Tracker, Active control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Kidney Transplant
Pilot Social Support Counseling Intervention for Kidney Transplant Candidates
Feasibility pilot social support counseling intervention for kidney transplant candidates
- Trial name
- NCT04363515
- Testing
- Social support network counseling intervention
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Allyson Hart
Chronic Kidney Failure, Frailty
Systemic Activation of Inflammasomes and Frailty in Older Candidates to Kidney Transplantation
Kidney transplantation (KT) benefit-risk ratio assessment is a challenge in a growing population of older patients with end-stage kidney disease.
- Conditions
- Chronic Kidney Failure, Frailty, Aging, Inflammation
- Trial name
- INTRA (NCT06887075)
- Testing
- Blood sample, Geriatric assessment standardized
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Bordeaux
Kidney Transplant, Living-Donor Kidney Transplant
Enhancing Education Regarding Living Donor Transplant Among Kidney Transplant Candidates
The primary purpose of this study is to test different methods by which kidney transplant centers can educate potential transplant candidates about living donor kidney transplant (LDKT).
- Conditions
- Kidney Transplant, Living-Donor Kidney Transplant, Chronic Kidney Disease, End-stage Renal Disease
- Trial name
- NCT01261910
- Testing
- Intensive initial education
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- St. Barnabas Medical Center
Diabetes, Type 1
Hybrid Closed-Loop Insulin Delivery System in Type 1 Diabetes Candidates for a Living Donor Kidney Transplant
The investigators' primary aim is to determine the impact of using hybrid closed-loop (HCL) system in patients with type 1 diabetes (T1D) and end stage renal disease (ESRD) prior to kidney transplantation.
- Trial name
- NCT03494010
- Testing
- Observation
- Where
- United States
- Sponsor
- Yale University
Kidney Transplant Candidates
Imlifidase in Living Donor Renal Transplantation Highly Sensitized Recipients
This is a Phase II, pilot, prospective, unicentric trial, to evaluate Imlifidase could improve the transplantability of the highly sensitized patients with good outcomes respect to survival and functionality of the graft.
- Trial name
- LIVEDES (NCT06461546)
- Testing
- Imlifidase
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Kidney Transplant
Social Support Counseling Intervention for Kidney Transplant Candidates
Virtual Coaching for Potential Kidney Transplant Patients
- Trial name
- JtT (NCT06147076)
- Testing
- Social Support Network Counseling Intervention
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Hennepin Healthcare Research Institute
End Stage Renal Disease
Pharmacokinetics of Immunosuppressants in Renal Transplant Candidates Who Have Undergone Laparoscopic Sleeve Gastrectomy
The purpose of this study is to evaluate how quickly and to what extent different immunosuppressants are absorbed into the blood (this is called pharmacokinetics) in renal transplant candidates who have undergone a laparoscopic…
- Trial name
- NCT02221583
- Testing
- Astagraf XL, Prograf, Mycophenolate mofetil
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Cincinnati
Chronic Kidney Disease (CKD), Kidney Transplant
Remote vs In-Person Prehabilitation for Kidney Transplant Candidates
Patients with advanced chronic kidney disease awaiting deceased-donor kidney transplantation frequently experience progressive functional decline, frailty, reduced mobility, and poor quality of life while on the transplant…
- Conditions
- Chronic Kidney Disease (CKD), Kidney Transplant, Frailty, Prehabilitation
- Trial name
- KIDFIT (NCT07701382)
- Testing
- In-Person Multimodal Prehabilitation, Remote Multimodal Prehabilitation
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Hospital Clinic of Barcelona
Prehabilitation, Kidney Transplant Candidates
PREhabilitation of Candidates for REnal Transplantation
In this study a personalized, multi modal prehabilitation intervention will be offered to n = 64 patients on the kidney transplant waiting-list. The control group (n = 64) will receive care as usual.
- Conditions
- Prehabilitation, Kidney Transplant Candidates, Frailty
- Trial name
- PreCareTx (NCT05489432)
- Testing
- Exercise
- Where
- Netherlands
- Volunteers
- 128 people
- Sponsor
- University Medical Center Groningen
Kidney Transplantation, Frailty
Prehabilitation for Kidney Transplant Candidates
This interventional trial seeks to determine the feasibility of wearable sensors to provide data from patients while undergoing supervised exercise.
- Conditions
- Kidney Transplantation, Frailty, Chronic Kidney Insufficiency
- Trial name
- NCT06886256
- Testing
- Polar H10 Heart Rate Monitor, Empatica EmbracePlus, Apple Watch Ultra 2
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Methodist Hospital Research Institute
Renal Transplantation
The Effect of Simvastatin on Desensitization of Panel-Positive Kidney Transplant Candidates
Patients with panel reactive antibodies have many difficulties to find a crossmatch-negative kidney for transplantation and are at the risk of post transplantation rejection more than other transplanted patients.
- Trial name
- NCT00693576
- Testing
- simvastatin
- Where
- Iran
- Volunteers
- 82 people
- Sponsor
- Shiraz University of Medical Sciences
Transplant
Simultaneous Prospective Kidney Transplant Assessment in Combined Liver Kidney Candidates
The purpose of the study is to determine how much a persons kidney function recovers after receiving a simultaneous liver kidney transplant.
- Trial name
- RECOVERY (NCT05717842)
- Testing
- Nuclear Medicine Scan
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Indiana University
Chronic Kidney Diseases, Hyperparathyroidism, Secondary
Analysis of Bone Microarchitecture With HR-pQCT of Patients With Chronic Kidney Disease (CKD) Candidates for Renal Transplantation
While the duration of renal transplant function has increased over the last decade kidney transplanted patients (KTP) still exhibit a fracture risk 4 times higher than in the general population.
- Trial name
- TRANSBONE (NCT02523209)
- Testing
- HR-pQCT, DEXA
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne