Clinical trials: Kidney Stones, open to volunteers
Kidney Stones
CaOx Stone Prevention
This single-center randomized controlled trial at Mount Sinai West will enroll 80 patients undergoing percutaneous nephrolithotomy for calcium oxalate stones.
- Trial name
- NCT07225764
- Testing
- Chlorthalidone, Low oxalate diet
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pediatric Renal Stones
Efficacy and Safety of Flexible Ureteroscopy With Flexible Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheath
Mini-percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) are both effective treatment modalities for renal calculi measuring up to 2.5 cm in pediatric patients, demonstrating similar efficacy and…
- Trial name
- NCT07763743
- Testing
- Flexible Ureteroscopy
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Urolithiasis, Kidney Stones
Pain Control During ESWL Using Non-Opioid Analgesics
This prospective randomized controlled trial aims to compare the analgesic efficacy of three non-opioid analgesics (ibuprofen, paracetamol, and tenoxicam) during extracorporeal shock wave lithotripsy (ESWL).
- Conditions
- Urolithiasis, Kidney Stones, Ureteral Stones
- Trial name
- ESWL-PAIN (NCT07512297)
- Testing
- Ibuprofen (Brufen®), Paracetamol (drug), Tenoxicam
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- University of Gaziantep
Urolithiasis, Renal Stones
Predicting the Success of Flexible Ureterorenoscopy for Kidney and Upper Ureter Stones
This observational study aims to test how well a specific medical scoring tool, called a nomogram, can predict the success of a common minimally invasive surgery for kidney stones.
- Conditions
- Urolithiasis, Renal Stones, Upper Ureteric Stones, Urinary Stone Disease
- Trial name
- NCT07753096
- Volunteers
- 70 people
- Sponsor
- Assiut University
Kidney Stones, Urolithiasis
DISON I - Directly Integrated Suction and Optics System for the Treatment of Nephrolithiasis
A single-arm, multicenter, international, prospective interventional study designed to evaluate the safety and performance of an investigational device during retrograde intrarenal surgery for the treatment of renal calculi.
- Conditions
- Kidney Stones, Urolithiasis, Nephrolithiasis
- Trial name
- DISON I (NCT07712861)
- Testing
- RIRS with Investigational Device
- Where
- 5 sites in Argentina, Canada and 3 more
- Volunteers
- 75 people
- Sponsor
- Ventaris Surgical Incorporated
Renal Stones
Ureteroscopic Lithotripsy for Renal Stones Using a Sheathless Approach or Using a Flexible and Navigable Ureteral Access Sheath (FANS)
The primary aim of the study is to compare stone free rates following ureteroscopic (URS) lithotripsy for renal stones with Thulium Fiber Laser (TFL) using a sheathless approach (low power laser settings) or using a flexible and…
- Trial name
- NCT07741084
- Testing
- Sheathless URS, FANS, low power, FANS, high power
- Where
- Norway
- Volunteers
- 225 people
- Sponsor
- Haukeland University Hospital
Urinary Stone
2D:4D Digit Ratio and Urinary Stone Disease
This prospective observational case-control study will investigate whether the 2D:4D digit ratio is associated with urinary stone disease.
- Trial name
- NCT07736924
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Emrah Kızılay
Urolithiasis, Stones, Kidney
Trial of Ureteroscopy vs Steerable Continuous Flow Aspiration Technology
The goal of this clinical trial is to compare Steerable Ureteroscopic Renal Evacuation (SURE) using the CVAC System and standard ureteroscopy (URS) with laser lithotripsy for the treatment of urolithiasis.
- Conditions
- Urolithiasis, Stones, Kidney, Renal Stones, Kidney Stones
- Trial name
- TRUST (NCT07101809)
- Testing
- Steerable Ureteroscopic Renal Evacuation (SURE) using the CVAC System, Standard Ureteroscopy (URS)
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Calyxo, Inc.
Urolithiasis, Kidney Stone
Effects of Virtual Reality Education on Anxiety and Learning in Patients Undergoing Urolithiasis Surgery
This randomized controlled trial aims to evaluate the effects of two-tier virtual reality-based preoperative education on anxiety, learning knowledge, self-care ability, and cognitive load in patients undergoing urolithiasis…
- Conditions
- Urolithiasis, Kidney Stone, Ureter Stones
- Trial name
- VR-URO (NCT07620873)
- Testing
- VR Education, Two-Tier VR Education
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Wei-Lin, Huang
Kidney Stones, Nephrolithiasis
Comparison of Different Ventilation Modes for Reducing Kidney Motion During Retrograde Intrarenal Surgery
This randomized clinical trial will compare four ventilation strategies during retrograde intrarenal surgery performed under general anesthesia.
- Trial name
- RIRS-VENT (NCT07705646)
- Testing
- Standard Ventilation, Hypoventilation, Intermittent Apnea Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Pediatric Renal Stone
Retrograde Intrarenal Surgery Versus Mini Percutaneous Nephrolithotomy
Pediatric nephrolithiasis accounts for approximately 2-3% of all stone disease cases, with recent reports indicating a rising prevalence of up to 10.6%. This increasing incidence poses a growing public health concern.
- Trial name
- NCT07700251
- Testing
- Retrograde Intrarenal Surgery
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Valley University
Kidney Stones, Complex Renal Calculi
Modified Mini-PCNL Versus Standard PCNL for Complex Kidney Stones
Kidney stones that are large or complex are often treated with percutaneous nephrolithotomy, also called PCNL. Standard PCNL uses a larger access tract and is effective for removing complex kidney stones, but it may be associated…
- Trial name
- MIMIC-PCNL (NCT07697677)
- Testing
- 20 Fr Modified Mini Percutaneous Nephrolithotomy, 24 Fr Standard Percutaneous Nephrolithotomy
- Where
- China
- Volunteers
- 1,380 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stones, Nephrolithiasis
Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)
This research study is being conducted to assess the ability and efficiency of two laser systems to break up kidney stones during ureteroscopy with laser lithotripsy for kidney stone treatment.
- Trial name
- NCT06721975
- Testing
- Thulio pulsed Thulium:YAG (p-Tm:YAG), Thulium Laser Fiber (TFL)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Kidney Stone, Stone, Kidney
Kidney Stone Inflammation
This observational study aims to look at the connections between kidney stones, insulin resistance, and inflammation. The researchers hypothesize that people who form calcium kidney stones and have insulin resistance may have…
- Trial name
- NCT06436235
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Kidney Calculi, Kidney Stones
Comparison of Vacuum-Assisted and Conventional Ureteral Access Sheath in Retrograde Intrarenal Surgery
This study aims to compare the efficacy and safety, the ratio of stone-free rates, and complications of two types of access sheaths used in retrograde intrarenal surgery to treat upper urothelial stones.
- Trial name
- NCT06684756
- Testing
- Retrograde intrarenal surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Namik Kemal University
Pediatric Urolithiasis, Kidney Stone
Standard Versus Flexible and Navigable Suction Ureteral Access Sheath in Pediatric Flexible Ureterorenoscopy for Renal Stones < 2 cm
This randomized controlled trial aims to compare the efficacy and safety of a Flexible and Navigable Suction Ureteral Access Sheath (FANS) versus a standard ureteral access sheath during flexible ureterorenoscopy (FURS) in…
- Conditions
- Pediatric Urolithiasis, Kidney Stone, Nephrolithiasis
- Trial name
- FANS-UAS (NCT07689565)
- Testing
- Standard Ureteral Access Sheath (Boston Scientific)., Flexible and Navigable Suction UAS (ClearPetra).
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Kidney Stones, Urine Specimen Collection
The Effect of Apple Cider Vinegar Supplementation on 24-hour Urine Chemistry in Adults
This is a single-center prospective cohort study to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.
- Trial name
- NCT07389226
- Testing
- Apple Cider Vinegar
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Thulium Fiber Laser, Fans
Fragmentation Vs Dusting With FANS for Renal Stones Less Than 2cm: A Randomized Controlled Study
The use of FANS has changed the operative landscape of RIRS by allowing continuous active suction-assisted clearance of ablated stone material in real time.
- Conditions
- Thulium Fiber Laser, Fans, Lithotripsy, Laser, Renal Stone
- Trial name
- NCT07639385
- Testing
- Dusting, Fragmentation
- Volunteers
- 86 people
- Sponsor
- Bir Hospital
Kidney Stone
Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis
The purpose of this study is to compare two variations of the mini-PCNL procedure using either a vacuum-assisted sheath or standard sheath which are both used for the surgical treatment of kidney stones.
- Trial name
- NCT05993546
- Testing
- vacuum assisted sheath, passive suction via conventional sheath
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- The Cleveland Clinic
Kidney Stones, Urolithiasis
PMCF Investigation of MODULITH® SLX-F2 With StorM-Track in Patients With Kidney Stones
Extracorporeal shockwave lithotripsy (ESWL) is a non-invasive standard treatment for kidney stones. This study will be conducted to evaluate the effectiveness of ESWL using MODULITH® SLX-F2 with stone tracking, compared to…
- Trial name
- NCT07272720
- Testing
- ESWL with kidney stone tracking (StorM-Track), Standard ESWL without stone tracking (StorM-Track disabled)
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- Storz Medical AG